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An Empirical Method of Detecting Time-Dependent Confounding: An Observational Study of Next Day Delirium in a Medical ICU.

International journal of statistics in medical research

Murphy TE, Van Ness PH, Araujo KL, Pisani MA.
PMID: 26798411
Int J Stat Med Res. 2016;5(1):41-47. doi: 10.6000/1929-6029.2016.05.01.4. Epub 2016 Jan 08.

Longitudinal research on older persons in the medical intensive care unit (MICU) is often complicated by the time-dependent confounding of concurrently administered interventions such as medications and intubation. Such temporal confounding can bias the respective longitudinal associations between concurrently...

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Murphy TE, Van Ness PH, Araujo KL, et al. An Empirical Method of Detecting Time-Dependent Confounding: An Observational Study of Next Day Delirium in a Medical ICU. Int J Stat Med Res. 2016;5(1):41-47doi: 10.6000/1929-6029.2016.05.01.4.
Murphy, T. E., Van Ness, P. H., Araujo, K. L., & Pisani, M. A. (2016). An Empirical Method of Detecting Time-Dependent Confounding: An Observational Study of Next Day Delirium in a Medical ICU. International journal of statistics in medical research, 5(1), 41-47. https://doi.org/10.6000/1929-6029.2016.05.01.4
Murphy, T E, et al. "An Empirical Method of Detecting Time-Dependent Confounding: An Observational Study of Next Day Delirium in a Medical ICU." International journal of statistics in medical research vol. 5,1 (2016): 41-47. doi: https://doi.org/10.6000/1929-6029.2016.05.01.4
Murphy TE, Van Ness PH, Araujo KL, Pisani MA. An Empirical Method of Detecting Time-Dependent Confounding: An Observational Study of Next Day Delirium in a Medical ICU. Int J Stat Med Res. 2016;5(1):41-47. doi: 10.6000/1929-6029.2016.05.01.4. Epub 2016 Jan 08. PMID: 26798411; PMCID: PMC4718607.
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Modifications in Organic Acid Profiles During Fruit Development and Ripening: Correlation or Causation?.

Frontiers in plant science

Batista-Silva W, Nascimento VL, Medeiros DB, Nunes-Nesi A, Ribeiro DM, Zsögön A, Araújo WL.
PMID: 30524461
Front Plant Sci. 2018 Nov 20;9:1689. doi: 10.3389/fpls.2018.01689. eCollection 2018.

The pivotal role of phytohormones during fruit development and ripening is considered established knowledge in plant biology. Perhaps less well-known is the growing body of evidence suggesting that organic acids play a key function in plant development and, in...

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Batista-Silva W, Nascimento VL, Medeiros DB, et al. Modifications in Organic Acid Profiles During Fruit Development and Ripening: Correlation or Causation?. Front Plant Sci. 2018;9:1689doi: 10.3389/fpls.2018.01689.
Batista-Silva, W., Nascimento, V. L., Medeiros, D. B., Nunes-Nesi, A., Ribeiro, D. M., Zsögön, A., & Araújo, W. L. (2018). Modifications in Organic Acid Profiles During Fruit Development and Ripening: Correlation or Causation?. Frontiers in plant science, 91689. https://doi.org/10.3389/fpls.2018.01689
Batista-Silva, Willian, et al. "Modifications in Organic Acid Profiles During Fruit Development and Ripening: Correlation or Causation?." Frontiers in plant science vol. 9 (2018): 1689. doi: https://doi.org/10.3389/fpls.2018.01689
Batista-Silva W, Nascimento VL, Medeiros DB, Nunes-Nesi A, Ribeiro DM, Zsögön A, Araújo WL. Modifications in Organic Acid Profiles During Fruit Development and Ripening: Correlation or Causation?. Front Plant Sci. 2018 Nov 20;9:1689. doi: 10.3389/fpls.2018.01689. eCollection 2018. PMID: 30524461; PMCID: PMC6256983.
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Spatio-temporal characterization of the fruit metabolism in contrasting accessions of Macauba (Acrocomia aculeata).

Plant physiology and biochemistry : PPB

Sá ACDS, Omena-Garcia RP, Pereira GL, Rodrigues-Salvador A, Araújo WL, Motoike SY, Nunes-Nesi A.
PMID: 34968988
Plant Physiol Biochem. 2021 Dec 24;171:14-25. doi: 10.1016/j.plaphy.2021.12.020. Epub 2021 Dec 24.

Although Macauba (Acrocomia aculeata) has been highlighted by its high-quality oil to fit edible and nonedible purposes, data addressing carbon and nitrogen metabolism underlying development and ripening of fruits remain scarce. In addition, accessions of Macauba exibit varied oil...

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Sá ACDS, Omena-Garcia RP, Pereira GL, et al. Spatio-temporal characterization of the fruit metabolism in contrasting accessions of Macauba (Acrocomia aculeata). Plant Physiol Biochem. 2021;171:14-25doi: 10.1016/j.plaphy.2021.12.020.
Sá, A. C. D. S., Omena-Garcia, R. P., Pereira, G. L., Rodrigues-Salvador, A., Araújo, W. L., Motoike, S. Y., & Nunes-Nesi, A. (2021). Spatio-temporal characterization of the fruit metabolism in contrasting accessions of Macauba (Acrocomia aculeata). Plant physiology and biochemistry : PPB, 17114-25. https://doi.org/10.1016/j.plaphy.2021.12.020
Sá, Ana Carolina Dos Santos, et al. "Spatio-temporal characterization of the fruit metabolism in contrasting accessions of Macauba (Acrocomia aculeata)." Plant physiology and biochemistry : PPB vol. 171 (2021): 14-25. doi: https://doi.org/10.1016/j.plaphy.2021.12.020
Sá ACDS, Omena-Garcia RP, Pereira GL, Rodrigues-Salvador A, Araújo WL, Motoike SY, Nunes-Nesi A. Spatio-temporal characterization of the fruit metabolism in contrasting accessions of Macauba (Acrocomia aculeata). Plant Physiol Biochem. 2021 Dec 24;171:14-25. doi: 10.1016/j.plaphy.2021.12.020. Epub 2021 Dec 24. PMID: 34968988.
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Convolutional Neural Network-Based Clinical Predictors of Oral Dysplasia: Class Activation Map Analysis of Deep Learning Results.

Cancers

Camalan S, Mahmood H, Binol H, Araújo ALD, Santos-Silva AR, Vargas PA, Lopes MA, Khurram SA, Gurcan MN.
PMID: 33799466
Cancers (Basel). 2021 Mar 14;13(6). doi: 10.3390/cancers13061291.

Oral cancer/oral squamous cell carcinoma is among the top ten most common cancers globally, with over 500,000 new cases and 350,000 associated deaths every year worldwide. There is a critical need for objective, novel technologies that facilitate early, accurate...

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Camalan S, Mahmood H, Binol H, et al. Convolutional Neural Network-Based Clinical Predictors of Oral Dysplasia: Class Activation Map Analysis of Deep Learning Results. Cancers (Basel). 2021;13(6)doi: 10.3390/cancers13061291.
Camalan, S., Mahmood, H., Binol, H., Araújo, A. L. D., Santos-Silva, A. R., Vargas, P. A., Lopes, M. A., Khurram, S. A., & Gurcan, M. N. (2021). Convolutional Neural Network-Based Clinical Predictors of Oral Dysplasia: Class Activation Map Analysis of Deep Learning Results. Cancers, 13(6), . https://doi.org/10.3390/cancers13061291
Camalan, Seda, et al. "Convolutional Neural Network-Based Clinical Predictors of Oral Dysplasia: Class Activation Map Analysis of Deep Learning Results." Cancers vol. 13,6 (2021). doi: https://doi.org/10.3390/cancers13061291
Camalan S, Mahmood H, Binol H, Araújo ALD, Santos-Silva AR, Vargas PA, Lopes MA, Khurram SA, Gurcan MN. Convolutional Neural Network-Based Clinical Predictors of Oral Dysplasia: Class Activation Map Analysis of Deep Learning Results. Cancers (Basel). 2021 Mar 14;13(6). doi: 10.3390/cancers13061291. PMID: 33799466; PMCID: PMC8001078.
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Corrigendum to: Thioredoxin-mediated regulation of (photo)respiration and central metabolism.

Journal of experimental botany

da Fonseca-Pereira P, Souza PVL, Fernie AR, Timm S, Daloso DM, Araújo WL.
PMID: 34878538
J Exp Bot. 2021 Dec 08; doi: 10.1093/jxb/erab446. Epub 2021 Dec 08.

No abstract available.

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da Fonseca-Pereira P, Souza PVL, Fernie AR, et al. Corrigendum to: Thioredoxin-mediated regulation of (photo)respiration and central metabolism. J Exp Bot. 2021;doi: 10.1093/jxb/erab446.
da Fonseca-Pereira, P., Souza, P. V. L., Fernie, A. R., Timm, S., Daloso, D. M., & Araújo, W. L. (2021). Corrigendum to: Thioredoxin-mediated regulation of (photo)respiration and central metabolism. Journal of experimental botany, . https://doi.org/10.1093/jxb/erab446
da Fonseca-Pereira, Paula, et al. "Corrigendum to: Thioredoxin-mediated regulation of (photo)respiration and central metabolism." Journal of experimental botany vol. (2021). doi: https://doi.org/10.1093/jxb/erab446
da Fonseca-Pereira P, Souza PVL, Fernie AR, Timm S, Daloso DM, Araújo WL. Corrigendum to: Thioredoxin-mediated regulation of (photo)respiration and central metabolism. J Exp Bot. 2021 Dec 08; doi: 10.1093/jxb/erab446. Epub 2021 Dec 08. PMID: 34878538.
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Sensitivity of Guillain-Barre Syndrome Surveillance in the Brazilian Federal District, using the Capture-Recapture Method.

Journal of infection in developing countries

De Morais Oliveira AF, Gallo LG, Bastos MM, Abrahão AA, Rufalco-Moutinho P, Malta JMAS, Garcia KKS, Matos LM, Araújo WN.
PMID: 34780374
J Infect Dev Ctries. 2021 Oct 31;15(10):1507-1514. doi: 10.3855/jidc.13457.

INTRODUCTION: Guillain-Barre Syndrome (GBS) is an acute immune-mediated polyneuropathy that compromises the peripheral and cranial nerves. It is characterized by rapid-onset paresthesia accompanied by progressive weakness in the lower extremities followed by symmetric ascending paralysis.METHODOLOGY: assessment of sensitivity to...

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De Morais Oliveira AF, Gallo LG, Bastos MM, et al. Sensitivity of Guillain-Barre Syndrome Surveillance in the Brazilian Federal District, using the Capture-Recapture Method. J Infect Dev Ctries. 2021;15(10):1507-1514doi: 10.3855/jidc.13457.
De Morais Oliveira, A. F., Gallo, L. G., Bastos, M. M., Abrahão, A. A., Rufalco-Moutinho, P., Malta, J. M. A. S., Garcia, K. K. S., Matos, L. M., & Araújo, W. N. (2021). Sensitivity of Guillain-Barre Syndrome Surveillance in the Brazilian Federal District, using the Capture-Recapture Method. Journal of infection in developing countries, 15(10), 1507-1514. https://doi.org/10.3855/jidc.13457
De Morais Oliveira, Ana Flavia, et al. "Sensitivity of Guillain-Barre Syndrome Surveillance in the Brazilian Federal District, using the Capture-Recapture Method." Journal of infection in developing countries vol. 15,10 (2021): 1507-1514. doi: https://doi.org/10.3855/jidc.13457
De Morais Oliveira AF, Gallo LG, Bastos MM, Abrahão AA, Rufalco-Moutinho P, Malta JMAS, Garcia KKS, Matos LM, Araújo WN. Sensitivity of Guillain-Barre Syndrome Surveillance in the Brazilian Federal District, using the Capture-Recapture Method. J Infect Dev Ctries. 2021 Oct 31;15(10):1507-1514. doi: 10.3855/jidc.13457. PMID: 34780374.
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Epidermal growth factor receptor and K-Ras in non-small cell lung cancer-molecular pathways involved and targeted therapies.

World journal of clinical oncology

de Mello RA, Marques DS, Medeiros R, Araújo AM.
PMID: 22087435
World J Clin Oncol. 2011 Nov 10;2(11):367-76. doi: 10.5306/wjco.v2.i11.367.

Lung cancer is currently the leading cause of cancer death in Western nations. Non-small cell lung cancer (NSCLC) represents 80% of all lung cancers, and adenocarcinoma is the predominant histological type. Despite the intensive research carried out on this...

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de Mello RA, Marques DS, Medeiros R, et al. Epidermal growth factor receptor and K-Ras in non-small cell lung cancer-molecular pathways involved and targeted therapies. World J Clin Oncol. 2011;2(11):367-76doi: 10.5306/wjco.v2.i11.367.
de Mello, R. A., Marques, D. S., Medeiros, R., & Araújo, A. M. (2011). Epidermal growth factor receptor and K-Ras in non-small cell lung cancer-molecular pathways involved and targeted therapies. World journal of clinical oncology, 2(11), 367-76. https://doi.org/10.5306/wjco.v2.i11.367
de Mello, Ramon Andrade, et al. "Epidermal growth factor receptor and K-Ras in non-small cell lung cancer-molecular pathways involved and targeted therapies." World journal of clinical oncology vol. 2,11 (2011): 367-76. doi: https://doi.org/10.5306/wjco.v2.i11.367
de Mello RA, Marques DS, Medeiros R, Araújo AM. Epidermal growth factor receptor and K-Ras in non-small cell lung cancer-molecular pathways involved and targeted therapies. World J Clin Oncol. 2011 Nov 10;2(11):367-76. doi: 10.5306/wjco.v2.i11.367. PMID: 22087435; PMCID: PMC3215775.
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Defocused high-power diode laser accelerates skin repair in a murine model through REDOX state modulation and reepithelization and collagen deposition stimulation.

Journal of photochemistry and photobiology. B, Biology

Mármora BC, Brochado FT, Schmidt TR, Santos LG, Araújo AA, Medeiros CACX, Ribeiro SB, Martins MAT, Pilar EFS, Wagner VP, Martins MD.
PMID: 34653929
J Photochem Photobiol B. 2021 Dec;225:112332. doi: 10.1016/j.jphotobiol.2021.112332. Epub 2021 Oct 09.

Skin wounds represent a burden in healthcare. Our aim was to investigate for the first time the effects of defocused high-power diode laser (DHPL) on skin healing in an animal experimental model and compare it with gold standard low-level...

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Mármora BC, Brochado FT, Schmidt TR, et al. Defocused high-power diode laser accelerates skin repair in a murine model through REDOX state modulation and reepithelization and collagen deposition stimulation. J Photochem Photobiol B. 2021;225:112332doi: 10.1016/j.jphotobiol.2021.112332.
Mármora, B. C., Brochado, F. T., Schmidt, T. R., Santos, L. G., Araújo, A. A., Medeiros, C. A. C. X., Ribeiro, S. B., Martins, M. A. T., Pilar, E. F. S., Wagner, V. P., & Martins, M. D. (2021). Defocused high-power diode laser accelerates skin repair in a murine model through REDOX state modulation and reepithelization and collagen deposition stimulation. Journal of photochemistry and photobiology. B, Biology, 225112332. https://doi.org/10.1016/j.jphotobiol.2021.112332
Mármora, Belkiss Câmara, et al. "Defocused high-power diode laser accelerates skin repair in a murine model through REDOX state modulation and reepithelization and collagen deposition stimulation." Journal of photochemistry and photobiology. B, Biology vol. 225 (2021): 112332. doi: https://doi.org/10.1016/j.jphotobiol.2021.112332
Mármora BC, Brochado FT, Schmidt TR, Santos LG, Araújo AA, Medeiros CACX, Ribeiro SB, Martins MAT, Pilar EFS, Wagner VP, Martins MD. Defocused high-power diode laser accelerates skin repair in a murine model through REDOX state modulation and reepithelization and collagen deposition stimulation. J Photochem Photobiol B. 2021 Dec;225:112332. doi: 10.1016/j.jphotobiol.2021.112332. Epub 2021 Oct 09. PMID: 34653929.
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Is there a dose-response of medial wedge insoles on lower limb biomechanics in people with pronated feet during walking and running?.

Gait & posture

Costa BL, Magalhães FA, Araújo VL, Richards J, Vieira FM, Souza TR, Trede R.
PMID: 34509041
Gait Posture. 2021 Oct;90:190-196. doi: 10.1016/j.gaitpost.2021.09.163. Epub 2021 Sep 06.

BACKGROUND: Although the effects of medial wedge insoles on lower limb biomechanics have been investigated, information about the effects of different magnitudes of medial posting is still lacking.RESEARCH QUESTION: What are the dose-response effects of medial wedge insoles with...

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Costa BL, Magalhães FA, Araújo VL, et al. Is there a dose-response of medial wedge insoles on lower limb biomechanics in people with pronated feet during walking and running?. Gait Posture. 2021;90:190-196doi: 10.1016/j.gaitpost.2021.09.163.
Costa, B. L., Magalhães, F. A., Araújo, V. L., Richards, J., Vieira, F. M., Souza, T. R., & Trede, R. (2021). Is there a dose-response of medial wedge insoles on lower limb biomechanics in people with pronated feet during walking and running?. Gait & posture, 90190-196. https://doi.org/10.1016/j.gaitpost.2021.09.163
Costa, Brunna Librelon, et al. "Is there a dose-response of medial wedge insoles on lower limb biomechanics in people with pronated feet during walking and running?." Gait & posture vol. 90 (2021): 190-196. doi: https://doi.org/10.1016/j.gaitpost.2021.09.163
Costa BL, Magalhães FA, Araújo VL, Richards J, Vieira FM, Souza TR, Trede R. Is there a dose-response of medial wedge insoles on lower limb biomechanics in people with pronated feet during walking and running?. Gait Posture. 2021 Oct;90:190-196. doi: 10.1016/j.gaitpost.2021.09.163. Epub 2021 Sep 06. PMID: 34509041.
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The role of the electron-transfer flavoprotein: ubiquinone oxidoreductase following carbohydrate starvation in Arabidopsis cell cultures.

Plant cell reports

Brito DS, Quinhones CGS, Neri-Silva R, Heinemann B, Schertl P, Cavalcanti JHF, Eubel H, Hildebrandt T, Nunes-Nesi A, Braun HP, Araújo WL.
PMID: 35031834
Plant Cell Rep. 2022 Jan 15; doi: 10.1007/s00299-021-02822-1. Epub 2022 Jan 15.

KEY MESSAGE: The functional absence of the electron-transfer flavoprotein: ubiquinone oxidoreductase (ETFQO) directly impacts electrons donation to the mitochondrial electron transport chain under carbohydrate-limiting conditions without major impacts on the respiration of cell cultures. Alternative substrates (e.g., amino acids)...

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Brito DS, Quinhones CGS, Neri-Silva R, et al. The role of the electron-transfer flavoprotein: ubiquinone oxidoreductase following carbohydrate starvation in Arabidopsis cell cultures. Plant Cell Rep. 2022;doi: 10.1007/s00299-021-02822-1.
Brito, D. S., Quinhones, C. G. S., Neri-Silva, R., Heinemann, B., Schertl, P., Cavalcanti, J. H. F., Eubel, H., Hildebrandt, T., Nunes-Nesi, A., Braun, H. P., & Araújo, W. L. (2022). The role of the electron-transfer flavoprotein: ubiquinone oxidoreductase following carbohydrate starvation in Arabidopsis cell cultures. Plant cell reports, . https://doi.org/10.1007/s00299-021-02822-1
Brito, Danielle S, et al. "The role of the electron-transfer flavoprotein: ubiquinone oxidoreductase following carbohydrate starvation in Arabidopsis cell cultures." Plant cell reports vol. (2022). doi: https://doi.org/10.1007/s00299-021-02822-1
Brito DS, Quinhones CGS, Neri-Silva R, Heinemann B, Schertl P, Cavalcanti JHF, Eubel H, Hildebrandt T, Nunes-Nesi A, Braun HP, Araújo WL. The role of the electron-transfer flavoprotein: ubiquinone oxidoreductase following carbohydrate starvation in Arabidopsis cell cultures. Plant Cell Rep. 2022 Jan 15; doi: 10.1007/s00299-021-02822-1. Epub 2022 Jan 15. PMID: 35031834.
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Metabolic shifts during fruit development in pungent and non-pungent peppers.

Food chemistry

Rodrigues-Salvador A, Lana-Costa J, Omena-Garcia RP, Batista-Silva W, Scossa F, Rosado-Souza L, Pérez-Díaz JL, Menezes-Silva PE, DaMatta FM, Sulpice R, Araújo WL, Zsögön A, Fernie AR, Nunes-Nesi A.
PMID: 34953242
Food Chem. 2021 Dec 14;375:131850. doi: 10.1016/j.foodchem.2021.131850. Epub 2021 Dec 14.

Fruit pungency is caused by the accumulation of capsaicinoids, secondary metabolites whose relation to primary metabolism remains unclear. We have selected ten geographically diverse accessions of Capsicum chinense Jacq with different pungency levels. A detailed metabolic profile was conducted...

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Rodrigues-Salvador A, Lana-Costa J, Omena-Garcia RP, et al. Metabolic shifts during fruit development in pungent and non-pungent peppers. Food Chem. 2021;375:131850doi: 10.1016/j.foodchem.2021.131850.
Rodrigues-Salvador, A., Lana-Costa, J., Omena-Garcia, R. P., Batista-Silva, W., Scossa, F., Rosado-Souza, L., Pérez-Díaz, J. L., Menezes-Silva, P. E., DaMatta, F. M., Sulpice, R., Araújo, W. L., Zsögön, A., Fernie, A. R., & Nunes-Nesi, A. (2021). Metabolic shifts during fruit development in pungent and non-pungent peppers. Food chemistry, 375131850. https://doi.org/10.1016/j.foodchem.2021.131850
Rodrigues-Salvador, Acácio, et al. "Metabolic shifts during fruit development in pungent and non-pungent peppers." Food chemistry vol. 375 (2021): 131850. doi: https://doi.org/10.1016/j.foodchem.2021.131850
Rodrigues-Salvador A, Lana-Costa J, Omena-Garcia RP, Batista-Silva W, Scossa F, Rosado-Souza L, Pérez-Díaz JL, Menezes-Silva PE, DaMatta FM, Sulpice R, Araújo WL, Zsögön A, Fernie AR, Nunes-Nesi A. Metabolic shifts during fruit development in pungent and non-pungent peppers. Food Chem. 2021 Dec 14;375:131850. doi: 10.1016/j.foodchem.2021.131850. Epub 2021 Dec 14. PMID: 34953242.
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Toxicometabolomics: Small Molecules to Answer Big Toxicological Questions.

Metabolites

Araújo AM, Carvalho F, Guedes de Pinho P, Carvalho M.
PMID: 34677407
Metabolites. 2021 Oct 09;11(10). doi: 10.3390/metabo11100692.

Given the high biological impact of classical and emerging toxicants, a sensitive and comprehensive assessment of the hazards and risks of these substances to organisms is urgently needed. In this sense, toxicometabolomics emerged as a new and growing field...

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Araújo AM, Carvalho F, Guedes de Pinho P, et al. Toxicometabolomics: Small Molecules to Answer Big Toxicological Questions. Metabolites. 2021;11(10)doi: 10.3390/metabo11100692.
Araújo, A. M., Carvalho, F., Guedes de Pinho, P., & Carvalho, M. (2021). Toxicometabolomics: Small Molecules to Answer Big Toxicological Questions. Metabolites, 11(10), . https://doi.org/10.3390/metabo11100692
Araújo, Ana Margarida, et al. "Toxicometabolomics: Small Molecules to Answer Big Toxicological Questions." Metabolites vol. 11,10 (2021). doi: https://doi.org/10.3390/metabo11100692
Araújo AM, Carvalho F, Guedes de Pinho P, Carvalho M. Toxicometabolomics: Small Molecules to Answer Big Toxicological Questions. Metabolites. 2021 Oct 09;11(10). doi: 10.3390/metabo11100692. PMID: 34677407; PMCID: PMC8539642.
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