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Showing 277 to 286 of 286 entries
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New means, new measures: assessing prescription drug-seeking indicators over 10 years of the opioid epidemic.

Addiction (Abingdon, England)

Perry BL, Odabaş M, Yang KC, Lee B, Kaminski P, Aronson B, Ahn YY, Oser CB, Freeman PR, Talbert JC.
PMID: 34227707
Addiction. 2022 Jan;117(1):195-204. doi: 10.1111/add.15635. Epub 2021 Jul 27.

BACKGROUND AND AIMS: Prescription drug-seeking (PDS) from multiple prescribers is a primary means of obtaining prescription opioids; however, PDS behavior has probably evolved in response to policy shifts, and there is little agreement about how to operationalize it. We...

Systems engineering analysis of diagnostic referral closed-loop processes.

BMJ open quality

Nehls N, Yap TS, Salant T, Aronson M, Schiff G, Olbricht S, Reddy S, Sternberg SB, Anderson TS, Phillips RS, Benneyan JC.
PMID: 34844935
BMJ Open Qual. 2021 Nov;10(4). doi: 10.1136/bmjoq-2021-001603.

BACKGROUND: Closing loops to complete diagnostic referrals remains a significant patient safety problem in most health systems, with 65%-73% failure rates and significant delays common despite years of improvement efforts, suggesting new approaches may be useful. Systems engineering (SE)...

Preventable deaths from SARS-CoV-2 in England and Wales: a systematic case series of coroners' reports during the COVID-19 pandemic.

BMJ evidence-based medicine

Swift B, Heneghan C, Aronson J, Howard D, Richards GC.
PMID: 34933933
BMJ Evid Based Med. 2021 Dec 21; doi: 10.1136/bmjebm-2021-111834. Epub 2021 Dec 21.

OBJECTIVES: To examine coroners' Prevention of Future Deaths (PFDs) reports to identify deaths involving SARS-CoV-2 that coroners deemed preventable.DESIGN: Consecutive case series.SETTING: England and Wales.PARTICIPANTS: Patients reported in 510 PFDs dated between 01 January 2020 and 28 June 2021,...

Challenges and practical solutions for managing secondary genomic findings in primary care.

European journal of medical genetics

Sebastian A, Carroll JC, Vanstone M, Clausen M, Kodida R, Reble E, Mighton C, Shickh S, Aronson M, Eisen A, Elser C, Lerner-Ellis J, Kim RH, Bombard Y.
PMID: 34768014
Eur J Med Genet. 2021 Nov 09;65(1):104384. doi: 10.1016/j.ejmg.2021.104384. Epub 2021 Nov 09.

Primary care providers will increasingly be tasked with managing most secondary findings from genomic sequencing, but literature exploring their capacity to manage findings beyond conventional genetic testing is limited. This study aimed to explore primary care providers' challenges and...

Glycemic Changes and Weight Loss Precede Pancreatic Ductal Adenocarcinoma by up to 3 Years in a Diverse Population.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Brewer MJ, Doucette JT, Bar-Mashiah A, Glickman JW, Kessel E, Aronson A, Lucas AL.
PMID: 34358720
Clin Gastroenterol Hepatol. 2021 Aug 03; doi: 10.1016/j.cgh.2021.07.046. Epub 2021 Aug 03.

BACKGROUND & AIMS: Elevations in fasting blood glucose are observed prior to the development of pancreatic ductal adenocarcinoma (PDAC). Our aim was to describe glycemic and weight changes that occur prior to PDAC diagnosis in a diverse population.METHODS: We...

Brief family history questionnaire to screen for Lynch syndrome in women with newly diagnosed non-serous, non-mucinous ovarian cancers.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Kim SR, Tone A, Kim R, Cesari M, Clarke B, Hart T, Aronson M, Holter S, Lytwyn A, Maganti M, Oldfield L, Gallinger S, Bernardini MQ, Oza AM, Djordjevic B, Lerner-Ellis J, Van de Laar E, Vicus D, Pugh TJ, Pollett A, Ferguson SE, Eiriksson L.
PMID: 35012974
Int J Gynecol Cancer. 2022 Jan 10; doi: 10.1136/ijgc-2021-003082. Epub 2022 Jan 10.

OBJECTIVES: While ovarian cancer is the third most common Lynch syndrome-associated cancer in women, there is no established screening strategy to identify Lynch syndrome in this population. The objective of this study was to assess whether the 4-item brief...

The prognostic value of positron emission tomography in the evaluation of suspected cardiac sarcoidosis.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Patel VN, Pieper JA, Poitrasson-Rivière A, Kopin D, Cascino T, Aaronson K, Murthy VL, Koelling T.
PMID: 34505261
J Nucl Cardiol. 2021 Sep 09; doi: 10.1007/s12350-021-02780-x. Epub 2021 Sep 09.

OBJECTIVES: To assess the prognostic value of positron emission tomography (PET) imaging in patients undergoing evaluation for known or suspected cardiac sarcoidosis (CS) while not on active immunotherapy.BACKGROUND: Previous studies have attempted to identify the value of PET imaging...

Use of Methylene Blue to Track Extensive Perineural Invasion.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]

Aronson A, Maxwell Salmon PJ.
PMID: 34559704
Dermatol Surg. 2021 Oct 01;47(10):1403-1404. doi: 10.1097/DSS.0000000000003191.

No abstract available.

DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells.

Cancer discovery

Chung J, Maruvka YE, Sudhaman S, Kelly J, Haradhvala NJ, Bianchi V, Edwards M, Forster VJ, Nunes NM, Galati MA, Komosa M, Deshmukh S, Cabric V, Davidson S, Zatzman M, Light N, Hayes R, Brunga L, Anderson ND, Ho B, Hodel KP, Siddaway R, Morrissy AS, Bowers DC, Larouche V, Bronsema A, Osborn M, Cole KA, Opocher E, Mason G, Thomas GA, George B, Ziegler DS, Lindhorst S, Vanan M, Yalon-Oren M, Reddy AT, Massimino M, Tomboc P, Van Damme A, Lossos A, Durno C, Aronson M, Morgenstern DA, Bouffet E, Huang A, Taylor MD, Villani A, Malkin D, Hawkins CE, Pursell ZF, Shlien A, Kunkel TA, Getz G, Tabori U.
PMID: 33355208
Cancer Discov. 2021 May;11(5):1176-1191. doi: 10.1158/2159-8290.CD-20-0790. Epub 2020 Dec 18.

Although replication repair deficiency, either by mismatch repair deficiency (MMRD) and/or loss of DNA polymerase proofreading, can cause hypermutation in cancer, microsatellite instability (MSI) is considered a hallmark of MMRD alone. By genome-wide analysis of tumors with germline and...

Stereotype Threat.

Shapiro JR, Aronson J.
UIID-AD: 615
2013;95-117.

No abstract available.

Showing 277 to 286 of 286 entries