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Showing 349 to 358 of 358 entries
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Fusion of multi-scale bag of deep visual words features of chest X-ray images to detect COVID-19 infection.

Scientific reports

Sitaula C, Shahi TB, Aryal S, Marzbanrad F.
PMID: 34903792
Sci Rep. 2021 Dec 13;11(1):23914. doi: 10.1038/s41598-021-03287-8.

Chest X-ray (CXR) images have been one of the important diagnosis tools used in the COVID-19 disease diagnosis. Deep learning (DL)-based methods have been used heavily to analyze these images. Compared to other DL-based methods, the bag of deep...

Draft Genome Sequence of the Sattazolin-Producing Strain .

Microbiology resource announcements

Aryal N, Aziz S, Rajbhandari P, Gross H.
PMID: 33707315
Microbiol Resour Announc. 2021 Mar 11;10(10). doi: 10.1128/MRA.00007-21.

Here, we report a 6.2-Mbp draft genome sequence of the bacterium

What lessons do the first Nationally Determined Contribution (NDC) formulation process and implementation outcome provide to the enhanced/updated NDC? A reality check from Nepal.

The Science of the total environment

Laudari HK, Aryal K, Bhusal S, Maraseni T.
PMID: 33198995
Sci Total Environ. 2021 Mar 10;759:143509. doi: 10.1016/j.scitotenv.2020.143509. Epub 2020 Nov 11.

Nationally Determined Contributions (NDCs) are the foundation of the Paris Agreement. So far, 190 Parties have submitted their NDCs. But how the NDC can be made comprehensive, unanimous and implementable so that the Paris climate goals can be achieved...

An invaginated pancreaticogastrostomy following subtotal stomach-preserving pancreaticoduodenectomy: A prospective observational study.

Asian journal of surgery

Komokata T, Nuruki K, Tada N, Imada R, Aryal B, Kaieda M, Sane S.
PMID: 33865665
Asian J Surg. 2021 Apr 14; doi: 10.1016/j.asjsur.2021.03.017. Epub 2021 Apr 14.

BACKGROUND/OBJECTIVE: Postoperative pancreatic fistula (POPF) leads to life-threatening complications after pancreaticoduodenectomy (PD). Pancreaticogastrostomy (PG) often adopted as a reconstruction technique after PD to prevent POPF. Delayed gastric emptying (DGE) following PD is the most common complication that compromises the...

Lung Transplantation of COVID-19 Patients.

Chest

King CS, Mannem H, Kukreja J, Aryal S, Tang D, Singer JP, Bharat A, Behr J, Nathan SD.
PMID: 34418410
Chest. 2021 Aug 19; doi: 10.1016/j.chest.2021.08.041. Epub 2021 Aug 19.

The COVID-19 pandemic has caused acute lung injury in millions of individuals worldwide. Some patients develop COVID-related acute respiratory distress syndrome (CARDS) and cannot be liberated from mechanical ventilation. Others may develop post-COVID fibrosis, resulting in substantial disability and...

Popliteal artery thrombosis as a rare complication of paroxysmal nocturnal hemoglobinuria (PNH): A case report.

International journal of surgery case reports

Bhusal K, Kadel PB, Bhandari K, Aryal S, Gyawali N, Kushwaha A, Shrestha KR, Shrestha A.
PMID: 34607268
Int J Surg Case Rep. 2021 Oct;87:106445. doi: 10.1016/j.ijscr.2021.106445. Epub 2021 Sep 24.

INTRODUCTION AND IMPORTANCE: Popliteal artery thrombosis a rare but life-threatening complication of Paroxysmal Nocturnal Hemoglobinuria caused due to hemolysis. Complications of further thrombotic event are common after initial management.CASE PRESENTATION: A 38 years old male, known case of PNH...

Targeting Bfl-1 via acute CDK9 inhibition overcomes intrinsic BH3-mimetic resistance in lymphomas.

Blood

Boiko S, Proia T, San Martin M, Gregory GP, Wu MM, Aryal N, Hattersley M, Shao W, Saeh JC, Fawell SE, Johnstone RW, Drew L, Cidado J.
PMID: 33259592
Blood. 2021 May 27;137(21):2947-2957. doi: 10.1182/blood.2020008528.

BH3 mimetics like venetoclax target prosurvival Bcl-2 family proteins and are important therapeutics in the treatment of hematological malignancies. We demonstrate that endogenous Bfl-1 expression can render preclinical lymphoma tumor models insensitive to Mcl-1 and Bcl-2 inhibitors. However, suppression...

Characterization and management of human-wildlife conflicts in mid-hills outside protected areas of Gandaki province, Nepal.

PloS one

Baral K, Sharma HP, Rimal B, Thapa-Magar K, Bhattarai R, Kunwar RM, Aryal A, Ji W.
PMID: 34797885
PLoS One. 2021 Nov 19;16(11):e0260307. doi: 10.1371/journal.pone.0260307. eCollection 2021.

With the intent to better management human wildlife conflict (HWC) and wildlife conservation in mid-hills outside protected areas of Gandaki province, Nepal, we analyzed the patterns and drivers of HWC. Using data collected from literature, government records and questionnaire...

High-throughput mediation analysis of human proteome and metabolome identifies mediators of post-bariatric surgical diabetes control.

Nature communications

Dreyfuss JM, Yuchi Y, Dong X, Efthymiou V, Pan H, Simonson DC, Vernon A, Halperin F, Aryal P, Konkar A, Sebastian Y, Higgs BW, Grimsby J, Rondinone CM, Kasif S, Kahn BB, Foster K, Seeley R, Goldfine A, Djordjilović V, Patti ME.
PMID: 34845204
Nat Commun. 2021 Nov 29;12(1):6951. doi: 10.1038/s41467-021-27289-2.

To improve the power of mediation in high-throughput studies, here we introduce High-throughput mediation analysis (Hitman), which accounts for direction of mediation and applies empirical Bayesian linear modeling. We apply Hitman in a retrospective, exploratory analysis of the SLIMM-T2D...

Experience of Treating COVID-19 With Remdesivir and Convalescent Plasma in a Resource-Limited Setting: A Prospective, Observational Study.

Open forum infectious diseases

Koirala J, Gyanwali P, Gerzoff RB, Bhattarai S, Nepal B, Manandhar R, Jha R, Sharma S, Sharma YR, Bastola A, Murphy H, Acharya S, Adhikari P, Rajkarnikari M, Vaidya KM, Panthi CL, Bista B, Giri G, Aryal S, Pant S, Pokharel A, Karki S, Basnet S, Koirala B, Dhimal M.
PMID: 34430672
Open Forum Infect Dis. 2021 Aug 21;8(8):ofab391. doi: 10.1093/ofid/ofab391. eCollection 2021 Aug.

BACKGROUND: Convalescent plasma therapy (CPT) and remdesivir (REM) have been approved for investigational use to treat coronavirus disease 2019 (COVID-19) in Nepal.METHODS: In this prospective, multicentered study, we evaluated the safety and outcomes of treatment with CPT and/or REM...

Showing 349 to 358 of 358 entries