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Showing 25 to 36 of 176 entries
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Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study.

Diabetologia

Downie CG, Dimos SF, Bien SA, Hu Y, Darst BF, Polfus LM, Wang Y, Wojcik GL, Tao R, Raffield LM, Armstrong ND, Polikowsky HG, Below JE, Correa A, Irvin MR, Rasmussen-Torvik LJF, Carlson CS, Phillips LS, Liu S, Pankow JS, Rich SS, Rotter JI, Buyske S, Matise TC, North KE, Avery CL, Haiman CA, Loos RJF, Kooperberg C, Graff M, Highland HM.
PMID: 34951656
Diabetologia. 2021 Dec 24; doi: 10.1007/s00125-021-05635-9. Epub 2021 Dec 24.

AIMS/HYPOTHESIS: Type 2 diabetes is a growing global public health challenge. Investigating quantitative traits, including fasting glucose, fasting insulin and HbAMETHODS: We conducted a GWAS of fasting glucose (n = 52,267), fasting insulin (n = 48,395) and HbARESULTS: Four...

Do Genetic Variants Modify the Effect of Smoking on Risk of Preeclampsia in Pregnancy?.

American journal of perinatology

Bauer AE, Avery CL, Shi M, Weinberg CR, Olshan AF, Harmon QE, Luo J, Yang J, Manuck T, Wu MC, Klungsøyr K, Trogstad L, Magnus P, Engel SM.
PMID: 34839469
Am J Perinatol. 2021 Nov 28; doi: 10.1055/s-0041-1740072. Epub 2021 Nov 28.

OBJECTIVE:  Maternal smoking is associated with as much as a 50% reduced risk of preeclampsia, despite increasing risk of other poor pregnancy outcomes that often co-occur with preeclampsia, such as preterm birth and fetal growth restriction. Researchers have long...

An aggressive CD4.

Veterinary and comparative oncology

Frankhouse KA, Rout ED, Hughes KL, Labadie JD, Yoshimoto JA, Lana SE, Avery PR, Avery AC.
PMID: 34792269
Vet Comp Oncol. 2021 Nov 18; doi: 10.1111/vco.12787. Epub 2021 Nov 18.

T-cell leukemia/lymphoma accounts for roughly 30% of all types of lymphoproliferative neoplasia in dogs. Two forms of T-cell lymphoma (T-zone and peripheral T-cell lymphoma) exhibit breed-specific predilections. During the course of routine immunophenotyping, we observed a breed-specific presentation of...

Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study.

Diabetologia

Downie CG, Dimos SF, Bien SA, Hu Y, Darst BF, Polfus LM, Wang Y, Wojcik GL, Tao R, Raffield LM, Armstrong ND, Polikowsky HG, Below JE, Correa A, Irvin MR, Rasmussen-Torvik LJF, Carlson CS, Phillips LS, Liu S, Pankow JS, Rich SS, Rotter JI, Buyske S, Matise TC, North KE, Avery CL, Haiman CA, Loos RJF, Kooperberg C, Graff M, Highland HM.
PMID: 34951656
Diabetologia. 2021 Dec 24; doi: 10.1007/s00125-021-05635-9. Epub 2021 Dec 24.

AIMS/HYPOTHESIS: Type 2 diabetes is a growing global public health challenge. Investigating quantitative traits, including fasting glucose, fasting insulin and HbAMETHODS: We conducted a GWAS of fasting glucose (n = 52,267), fasting insulin (n = 48,395) and HbARESULTS: Four...

Contribution of common chronic conditions to midlife physical function decline: The Study of Women's Health Across the Nation.

Women's midlife health

Lange-Maia BS, Karavolos K, Avery EF, Strotmeyer ES, Karvonen-Gutierrez CA, Appelhans BM, Janssen I, Dugan SA, Kravitz HM.
PMID: 32742664
Womens Midlife Health. 2020 Jul 28;6:6. doi: 10.1186/s40695-020-00053-0. eCollection 2020.

BACKGROUND: Chronic conditions are associated with worse physical function and commonly develop during midlife. We tested whether the presence of 8 chronic conditions, or the development of these conditions, is associated with declines in physical function among midlife women...

Anterior hippocampal dysfunction in early psychosis: a 2-year follow-up study.

Psychological medicine

McHugo M, Avery S, Armstrong K, Rogers BP, Vandekar SN, Woodward ND, Blackford JU, Heckers S.
PMID: 33875028
Psychol Med. 2021 Apr 20;1-10. doi: 10.1017/S0033291721001318. Epub 2021 Apr 20.

BACKGROUND: Cross-sectional studies indicate that hippocampal function is abnormal across stages of psychosis. Neural theories of psychosis pathophysiology suggest that dysfunction worsens with illness stage. Here, we test the hypothesis that hippocampal function is impaired in the early stage...

Hungry scale worms: Phylogenetics of .

ZooKeys

Hatch AS, Liew H, Hourdez S, Rouse GW.
PMID: 32476973
Zookeys. 2020 May 12;932:27-74. doi: 10.3897/zookeys.932.48532. eCollection 2020.

Polynoidae Kinberg, 1856 has five branchiate genera:

Updated prevalence, predictors and treatment outcomes for bronchiolitis obliterans syndrome after allogeneic stem cell transplantation.

Respiratory medicine

Pham J, Rangaswamy J, Avery S, Borg B, Martin C, Munsif M, Lin T, Dabscheck E.
PMID: 33383436
Respir Med. 2020 Dec 28;177:106286. doi: 10.1016/j.rmed.2020.106286. Epub 2020 Dec 28.

INTRODUCTION: Bronchiolitis obliterans syndrome (BOS) after allogeneic haemopoietic stem cell transplant (HSCT) is an under-recognised and difficult to treat disease. This occurs in the context of limited clinical research and inconsistent diagnostic criteria.METHOD: Retrospective data was collected on 275...

The expansion of human T-bet.

Science immunology

Keller B, Strohmeier V, Harder I, Unger S, Payne KJ, Andrieux G, Boerries M, Felixberger PT, Landry JJM, Nieters A, Rensing-Ehl A, Salzer U, Frede N, Usadel S, Elling R, Speckmann C, Hainmann I, Ralph E, Gilmour K, Wentink MWJ, van der Burg M, Kuehn HS, Rosenzweig SD, Kölsch U, von Bernuth H, Kaiser-Labusch P, Gothe F, Hambleton S, Vlagea AD, Garcia Garcia A, Alsina L, Markelj G, Avcin T, Vasconcelos J, Guedes M, Ding JY, Ku CL, Shadur B, Avery DT, Venhoff N, Thiel J, Becker H, Erazo-Borrás L, Trujillo-Vargas CM, Franco JL, Fieschi C, Okada S, Gray PE, Uzel G, Casanova JL, Fliegauf M, Grimbacher B, Eibel H, Ehl S, Voll RE, Rizzi M, Stepensky P, Benes V, Ma CS, Bossen C, Tangye SG, Warnatz K.
PMID: 34623902
Sci Immunol. 2021 Oct 15;6(64):eabh0891. doi: 10.1126/sciimmunol.abh0891. Epub 2021 Oct 08.

[Figure: see text].

The expansion of human T-bet.

Science immunology

Keller B, Strohmeier V, Harder I, Unger S, Payne KJ, Andrieux G, Boerries M, Felixberger PT, Landry JJM, Nieters A, Rensing-Ehl A, Salzer U, Frede N, Usadel S, Elling R, Speckmann C, Hainmann I, Ralph E, Gilmour K, Wentink MWJ, van der Burg M, Kuehn HS, Rosenzweig SD, Kölsch U, von Bernuth H, Kaiser-Labusch P, Gothe F, Hambleton S, Vlagea AD, Garcia Garcia A, Alsina L, Markelj G, Avcin T, Vasconcelos J, Guedes M, Ding JY, Ku CL, Shadur B, Avery DT, Venhoff N, Thiel J, Becker H, Erazo-Borrás L, Trujillo-Vargas CM, Franco JL, Fieschi C, Okada S, Gray PE, Uzel G, Casanova JL, Fliegauf M, Grimbacher B, Eibel H, Ehl S, Voll RE, Rizzi M, Stepensky P, Benes V, Ma CS, Bossen C, Tangye SG, Warnatz K.
PMID: 34623902
Sci Immunol. 2021 Oct 15;6(64):eabh0891. doi: 10.1126/sciimmunol.abh0891. Epub 2021 Oct 08.

[Figure: see text].

CoBRA: Containerized Bioinformatics Workflow for Reproducible ChIP/ATAC-seq Analysis.

Genomics, proteomics & bioinformatics

Qiu X, Feit AS, Feiglin A, Xie Y, Kesten N, Taing L, Perkins J, Gu S, Li Y, Cejas P, Zhou N, Jeselsohn R, Brown M, Shirley Liu X, Long HW.
PMID: 34284136
Genomics Proteomics Bioinformatics. 2021 Jul 17; doi: 10.1016/j.gpb.2020.11.007. Epub 2021 Jul 17.

Chromatin immunoprecipitation sequencing (ChIP-seq) and the Assay for Transposase-Accessible Chromatin with high-throughput sequencing (ATAC-seq) have become essential technologies to effectively measure protein-DNA interactions and chromatin accessibility. However, there is a need for a scalable and reproducible pipeline that incorporates...

Changes in physical activity levels and mental health during COVID-19: Prospective findings among adult twin pairs.

PloS one

Duncan GE, Avery AR, Tsang S, Williams BD, Seto E.
PMID: 34807944
PLoS One. 2021 Nov 22;16(11):e0260218. doi: 10.1371/journal.pone.0260218. eCollection 2021.

BACKGROUND: Physical distancing and other COVID-19 pandemic mitigation strategies have negatively impacted physical activity (PA) levels and mental health in cross-sectional studies. The purpose of this study was to investigate associations between changes in PA and mental health outcomes...

Showing 25 to 36 of 176 entries