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A new plasmid vector for DNA delivery using lactococci.

Genetic vaccines and therapy

Guimarães V, Innocentin S, Chatel JM, Lefèvre F, Langella P, Azevedo V, Miyoshi A.
PMID: 19208231
Genet Vaccines Ther. 2009 Feb 10;7:4. doi: 10.1186/1479-0556-7-4.

BACKGROUND: The use of food-grade lactococci as bacterial carriers to DNA delivery into epithelial cells is a new strategy to develop live oral DNA vaccine. Our goal was to develop a new plasmid, named pValac, for antigen delivery for...

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Guimarães V, Innocentin S, Chatel JM, et al. A new plasmid vector for DNA delivery using lactococci. Genet Vaccines Ther. 2009;7:4doi: 10.1186/1479-0556-7-4.
Guimarães, V., Innocentin, S., Chatel, J. M., Lefèvre, F., Langella, P., Azevedo, V., & Miyoshi, A. (2009). A new plasmid vector for DNA delivery using lactococci. Genetic vaccines and therapy, 74. https://doi.org/10.1186/1479-0556-7-4
Guimarães, Valeria, et al. "A new plasmid vector for DNA delivery using lactococci." Genetic vaccines and therapy vol. 7 (2009): 4. doi: https://doi.org/10.1186/1479-0556-7-4
Guimarães V, Innocentin S, Chatel JM, Lefèvre F, Langella P, Azevedo V, Miyoshi A. A new plasmid vector for DNA delivery using lactococci. Genet Vaccines Ther. 2009 Feb 10;7:4. doi: 10.1186/1479-0556-7-4. PMID: 19208231; PMCID: PMC2646724.
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Optic neuritis in an adult patient with chickenpox.

Case reports in ophthalmological medicine

Azevedo AR, Simões R, Silva F, Pina S, Santos C, Pêgo P, Silva F, Teixeira S.
PMID: 23320222
Case Rep Ophthalmol Med. 2012;2012:371584. doi: 10.1155/2012/371584. Epub 2012 Dec 19.

Central nervous system involvement in a patient with primary infection with Varicella zoster virus is rare, especially in the immunocompetent adult. In particular, isolated optic neuritis has been described in a small number of cases. The authors present a...

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Azevedo AR, Simões R, Silva F, et al. Optic neuritis in an adult patient with chickenpox. Case Rep Ophthalmol Med. 2012;2012:371584doi: 10.1155/2012/371584.
Azevedo, A. R., Simões, R., Silva, F., Pina, S., Santos, C., Pêgo, P., Silva, F., & Teixeira, S. (2012). Optic neuritis in an adult patient with chickenpox. Case reports in ophthalmological medicine, 2012371584. https://doi.org/10.1155/2012/371584
Azevedo, Ana Rita, et al. "Optic neuritis in an adult patient with chickenpox." Case reports in ophthalmological medicine vol. 2012 (2012): 371584. doi: https://doi.org/10.1155/2012/371584
Azevedo AR, Simões R, Silva F, Pina S, Santos C, Pêgo P, Silva F, Teixeira S. Optic neuritis in an adult patient with chickenpox. Case Rep Ophthalmol Med. 2012;2012:371584. doi: 10.1155/2012/371584. Epub 2012 Dec 19. PMID: 23320222; PMCID: PMC3535731.
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Effects of kangaroo care during painful procedures in preterm infants: a review.

Revista Brasileira de terapia intensiva

Maia Fde A, Azevedo VM, Gontijo Fde O.
PMID: 23949410
Rev Bras Ter Intensiva. 2011 Sep;23(3):370-3.

Although low-birth neonates are acknowledged to experience pain, many routine procedures continue to be conducted without proper pharmacological or non-pharmacological analgesia. Kangaroo care is a low-cost strategy that can be used in the preterm newborn. Mothers should be encouraged...

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Maia Fde A, Azevedo VM, Gontijo Fde O. Os efeitos da posição canguru em resposta aos procedimentos dolorosos em recém-nascidos pré-termo: uma revisão da literatura. Effects of kangaroo care during painful procedures in preterm infants: a review. Rev Bras Ter Intensiva. 2011;23(3):370-3
Maia, F. d. e. . A., Azevedo, V. M., & Gontijo, F. d. e. . O. (2011). Os efeitos da posição canguru em resposta aos procedimentos dolorosos em recém-nascidos pré-termo: uma revisão da literatura. Effects of kangaroo care during painful procedures in preterm infants: a review. Revista Brasileira de terapia intensiva, 23(3), 370-3.
Maia, Fernanda de Almeida, et al. "Os efeitos da posição canguru em resposta aos procedimentos dolorosos em recém-nascidos pré-termo: uma revisão da literatura." Effects of kangaroo care during painful procedures in preterm infants: a review. Revista Brasileira de terapia intensiva vol. 23,3 (2011): 370-3.
Maia Fde A, Azevedo VM, Gontijo Fde O. Os efeitos da posição canguru em resposta aos procedimentos dolorosos em recém-nascidos pré-termo: uma revisão da literatura. Effects of kangaroo care during painful procedures in preterm infants: a review. Rev Bras Ter Intensiva. 2011 Sep;23(3):370-3. Portuguese. PMID: 23949410.
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Zero-inflated Poisson regression models for QTL mapping applied to tick-resistance in a Gyr × Holstein F2 population.

Genetics and molecular biology

Silva FF, Tunin KP, Rosa GJ, da Silva MV, Azevedo AL, da Silva Verneque R, Machado MA, Packer IU.
PMID: 22215960
Genet Mol Biol. 2011 Oct;34(4):575-81. doi: 10.1590/S1415-47572011005000049. Epub 2011 Oct 01.

Now a days, an important and interesting alternative in the control of tick-infestation in cattle is to select resistant animals, and identify the respective quantitative trait loci (QTLs) and DNA markers, for posterior use in breeding programs. The number...

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Silva FF, Tunin KP, Rosa GJ, et al. Zero-inflated Poisson regression models for QTL mapping applied to tick-resistance in a Gyr × Holstein F2 population. Genet Mol Biol. 2011;34(4):575-81doi: 10.1590/S1415-47572011005000049.
Silva, F. F., Tunin, K. P., Rosa, G. J., da Silva, M. V., Azevedo, A. L., da Silva Verneque, R., Machado, M. A., & Packer, I. U. (2011). Zero-inflated Poisson regression models for QTL mapping applied to tick-resistance in a Gyr × Holstein F2 population. Genetics and molecular biology, 34(4), 575-81. https://doi.org/10.1590/S1415-47572011005000049
Silva, Fabyano Fonseca, et al. "Zero-inflated Poisson regression models for QTL mapping applied to tick-resistance in a Gyr × Holstein F2 population." Genetics and molecular biology vol. 34,4 (2011): 575-81. doi: https://doi.org/10.1590/S1415-47572011005000049
Silva FF, Tunin KP, Rosa GJ, da Silva MV, Azevedo AL, da Silva Verneque R, Machado MA, Packer IU. Zero-inflated Poisson regression models for QTL mapping applied to tick-resistance in a Gyr × Holstein F2 population. Genet Mol Biol. 2011 Oct;34(4):575-81. doi: 10.1590/S1415-47572011005000049. Epub 2011 Oct 01. PMID: 22215960; PMCID: PMC3229111.
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Indirect calibration between clinical observers - application to the New York Heart Association functional classification system.

BMC research notes

Severo M, Gaio R, Lourenço P, Alvelos M, Bettencourt P, Azevedo A.
PMID: 21813014
BMC Res Notes. 2011 Aug 03;4:276. doi: 10.1186/1756-0500-4-276.

BACKGROUND: Previous studies showed an inter-observer agreement for the NYHA classification of approximately 55%. The aim of this study was to calibrate the New York Heart Association (NYHA) classification system between observers, increasing its reliability.RESULTS: Among 1136 community-dwellers in...

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Severo M, Gaio R, Lourenço P, et al. Indirect calibration between clinical observers - application to the New York Heart Association functional classification system. BMC Res Notes. 2011;4:276doi: 10.1186/1756-0500-4-276.
Severo, M., Gaio, R., Lourenço, P., Alvelos, M., Bettencourt, P., & Azevedo, A. (2011). Indirect calibration between clinical observers - application to the New York Heart Association functional classification system. BMC research notes, 4276. https://doi.org/10.1186/1756-0500-4-276
Severo, Milton, et al. "Indirect calibration between clinical observers - application to the New York Heart Association functional classification system." BMC research notes vol. 4 (2011): 276. doi: https://doi.org/10.1186/1756-0500-4-276
Severo M, Gaio R, Lourenço P, Alvelos M, Bettencourt P, Azevedo A. Indirect calibration between clinical observers - application to the New York Heart Association functional classification system. BMC Res Notes. 2011 Aug 03;4:276. doi: 10.1186/1756-0500-4-276. PMID: 21813014; PMCID: PMC3160980.
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Diagnostic value of patterns of symptoms and signs of heart failure: application of latent class analysis with concomitant variables in a cross-sectional study.

BMJ open

Severo M, Gaio AR, Lourenço P, Alvelos M, Gonçalves A, Lunet N, Bettencourt P, Azevedo A.
PMID: 23148342
BMJ Open. 2012 Nov 12;2(6). doi: 10.1136/bmjopen-2012-001510. Print 2012.

OBJECTIVE: The diagnosis of heart failure (HF) requires a compatible clinical syndrome and demonstration of cardiac dysfunction by imaging or functional tests. Since individual symptoms and signs are generally unreliable and have limited value for diagnosing HF, the authors...

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Severo M, Gaio AR, Lourenço P, et al. Diagnostic value of patterns of symptoms and signs of heart failure: application of latent class analysis with concomitant variables in a cross-sectional study. BMJ Open. 2012;2(6)doi: 10.1136/bmjopen-2012-001510.
Severo, M., Gaio, A. R., Lourenço, P., Alvelos, M., Gonçalves, A., Lunet, N., Bettencourt, P., & Azevedo, A. (2012). Diagnostic value of patterns of symptoms and signs of heart failure: application of latent class analysis with concomitant variables in a cross-sectional study. BMJ open, 2(6), . https://doi.org/10.1136/bmjopen-2012-001510
Severo, Milton, et al. "Diagnostic value of patterns of symptoms and signs of heart failure: application of latent class analysis with concomitant variables in a cross-sectional study." BMJ open vol. 2,6 (2012). doi: https://doi.org/10.1136/bmjopen-2012-001510
Severo M, Gaio AR, Lourenço P, Alvelos M, Gonçalves A, Lunet N, Bettencourt P, Azevedo A. Diagnostic value of patterns of symptoms and signs of heart failure: application of latent class analysis with concomitant variables in a cross-sectional study. BMJ Open. 2012 Nov 12;2(6). doi: 10.1136/bmjopen-2012-001510. Print 2012. PMID: 23148342; PMCID: PMC3532992.
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Progression of 'OMICS' methodologies for understanding the pathogenicity of Corynebacterium pseudotuberculosis: the Brazilian experience.

Computational and structural biotechnology journal

Dorella FA, Gala-Garcia A, Pinto AC, Sarrouh B, Antunes CA, Ribeiro D, Aburjaile FF, Fiaux KK, Guimarães LC, Seyffert N, El-Aouar RA, Silva R, Hassan SS, Castro TL, Marques WS, Ramos R, Carneiro A, de Sá P, Miyoshi A, Azevedo V, Silva A.
PMID: 24688721
Comput Struct Biotechnol J. 2013 Oct 13;6:e201303013. doi: 10.5936/csbj.201303013. eCollection 2013.

Since the first successful attempt at sequencing the Corynebacterium pseudotuberculosis genome, large amounts of genomic, transcriptomic and proteomic data have been generated. C. pseudotuberculosis is an interesting bacterium due to its great zoonotic potential and because it causes considerable...

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Dorella FA, Gala-Garcia A, Pinto AC, et al. Progression of 'OMICS' methodologies for understanding the pathogenicity of Corynebacterium pseudotuberculosis: the Brazilian experience. Comput Struct Biotechnol J. 2013;6:e201303013doi: 10.5936/csbj.201303013.
Dorella, F. A., Gala-Garcia, A., Pinto, A. C., Sarrouh, B., Antunes, C. A., Ribeiro, D., Aburjaile, F. F., Fiaux, K. K., Guimarães, L. C., Seyffert, N., El-Aouar, R. A., Silva, R., Hassan, S. S., Castro, T. L., Marques, W. S., Ramos, R., Carneiro, A., de Sá, P., Miyoshi, A., Azevedo, V., & Silva, A. (2013). Progression of 'OMICS' methodologies for understanding the pathogenicity of Corynebacterium pseudotuberculosis: the Brazilian experience. Computational and structural biotechnology journal, 6e201303013. https://doi.org/10.5936/csbj.201303013
Dorella, Fernanda A, et al. "Progression of 'OMICS' methodologies for understanding the pathogenicity of Corynebacterium pseudotuberculosis: the Brazilian experience." Computational and structural biotechnology journal vol. 6 (2013): e201303013. doi: https://doi.org/10.5936/csbj.201303013
Dorella FA, Gala-Garcia A, Pinto AC, Sarrouh B, Antunes CA, Ribeiro D, Aburjaile FF, Fiaux KK, Guimarães LC, Seyffert N, El-Aouar RA, Silva R, Hassan SS, Castro TL, Marques WS, Ramos R, Carneiro A, de Sá P, Miyoshi A, Azevedo V, Silva A. Progression of 'OMICS' methodologies for understanding the pathogenicity of Corynebacterium pseudotuberculosis: the Brazilian experience. Comput Struct Biotechnol J. 2013 Oct 13;6:e201303013. doi: 10.5936/csbj.201303013. eCollection 2013. PMID: 24688721; PMCID: PMC3962224.
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Necrotizing sialometaplasia of palate: a case report.

Case reports in pathology

Garcia NG, Oliveira DT, Faustino SE, Azevedo AL.
PMID: 22957289
Case Rep Pathol. 2012;2012:679325. doi: 10.1155/2012/679325. Epub 2012 Aug 22.

Background. Necrotizing sialometaplasia (NS) is an uncommon benign reactive necrotizing inflammatory process involving minor salivary gland that often mimics malignancy both clinically and histopathologically. Case Report. We report the case of a healthy 26-year-old man with a painless swelling...

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Garcia NG, Oliveira DT, Faustino SE, et al. Necrotizing sialometaplasia of palate: a case report. Case Rep Pathol. 2012;2012:679325doi: 10.1155/2012/679325.
Garcia, N. G., Oliveira, D. T., Faustino, S. E., & Azevedo, A. L. (2012). Necrotizing sialometaplasia of palate: a case report. Case reports in pathology, 2012679325. https://doi.org/10.1155/2012/679325
Garcia, N G, et al. "Necrotizing sialometaplasia of palate: a case report." Case reports in pathology vol. 2012 (2012): 679325. doi: https://doi.org/10.1155/2012/679325
Garcia NG, Oliveira DT, Faustino SE, Azevedo AL. Necrotizing sialometaplasia of palate: a case report. Case Rep Pathol. 2012;2012:679325. doi: 10.1155/2012/679325. Epub 2012 Aug 22. PMID: 22957289; PMCID: PMC3432339.
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The biosimilars journey: current status and ongoing challenges.

Drugs in context

Kos IA, Azevedo VF, Neto DE, Kowalski SC.
PMID: 30302115
Drugs Context. 2018 Oct 01;7:212543. doi: 10.7573/dic.212543. eCollection 2018.

Biosimilar products are already approved and marketed in several countries. The Food and Drug Administration has approved ten different biosimilars, and the European Medicines Agency has approved 40. Even though this scenario has provided important experience with biosimilar products,...

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Kos IA, Azevedo VF, Neto DE, et al. The biosimilars journey: current status and ongoing challenges. Drugs Context. 2018;7:212543doi: 10.7573/dic.212543.
Kos, I. A., Azevedo, V. F., Neto, D. E., & Kowalski, S. C. (2018). The biosimilars journey: current status and ongoing challenges. Drugs in context, 7212543. https://doi.org/10.7573/dic.212543
Kos, Igor Age, et al. "The biosimilars journey: current status and ongoing challenges." Drugs in context vol. 7 (2018): 212543. doi: https://doi.org/10.7573/dic.212543
Kos IA, Azevedo VF, Neto DE, Kowalski SC. The biosimilars journey: current status and ongoing challenges. Drugs Context. 2018 Oct 01;7:212543. doi: 10.7573/dic.212543. eCollection 2018. PMID: 30302115; PMCID: PMC6172013.
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Whey Protein Isolate-Supplemented Beverage, Fermented by .

Frontiers in microbiology

Cordeiro BF, Oliveira ER, da Silva SH, Savassi BM, Acurcio LB, Lemos L, Alves JL, Carvalho Assis H, Vieira AT, Faria AMC, Ferreira E, Le Loir Y, Jan G, Goulart LR, Azevedo V, Carvalho RDO, do Carmo FLR.
PMID: 30258413
Front Microbiol. 2018 Sep 12;9:2035. doi: 10.3389/fmicb.2018.02035. eCollection 2018.

Mucositis is a clinically important gastrointestinal inflammatory infirmity, generated by antineoplastic drugs cytotoxic effects. The inflammatory process caused by this disease frequently leads to derangements in the alimentary tract and great malaise for the patient. Novel strategies are necessary...

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Cordeiro BF, Oliveira ER, da Silva SH, et al. Whey Protein Isolate-Supplemented Beverage, Fermented by . Front Microbiol. 2018;9:2035doi: 10.3389/fmicb.2018.02035.
Cordeiro, B. F., Oliveira, E. R., da Silva, S. H., Savassi, B. M., Acurcio, L. B., Lemos, L., Alves, J. L., Carvalho Assis, H., Vieira, A. T., Faria, A. M. C., Ferreira, E., Le Loir, Y., Jan, G., Goulart, L. R., Azevedo, V., Carvalho, R. D. O., & do Carmo, F. L. R. (2018). Whey Protein Isolate-Supplemented Beverage, Fermented by . Frontiers in microbiology, 92035. https://doi.org/10.3389/fmicb.2018.02035
Cordeiro, Bárbara F, et al. "Whey Protein Isolate-Supplemented Beverage, Fermented by ." Frontiers in microbiology vol. 9 (2018): 2035. doi: https://doi.org/10.3389/fmicb.2018.02035
Cordeiro BF, Oliveira ER, da Silva SH, Savassi BM, Acurcio LB, Lemos L, Alves JL, Carvalho Assis H, Vieira AT, Faria AMC, Ferreira E, Le Loir Y, Jan G, Goulart LR, Azevedo V, Carvalho RDO, do Carmo FLR. Whey Protein Isolate-Supplemented Beverage, Fermented by . Front Microbiol. 2018 Sep 12;9:2035. doi: 10.3389/fmicb.2018.02035. eCollection 2018. PMID: 30258413; PMCID: PMC6143704.
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Mutation of the Surface Layer Protein SlpB Has Pleiotropic Effects in the Probiotic .

Frontiers in microbiology

do Carmo FLR, Silva WM, Tavares GC, Ibraim IC, Cordeiro BF, Oliveira ER, Rabah H, Cauty C, da Silva SH, Canário Viana MV, Caetano ACB, Dos Santos RG, de Oliveira Carvalho RD, Jardin J, Pereira FL, Folador EL, Le Loir Y, Figueiredo HCP, Jan G, Azevedo V.
PMID: 30174657
Front Microbiol. 2018 Aug 17;9:1807. doi: 10.3389/fmicb.2018.01807. eCollection 2018.

No abstract available.

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do Carmo FLR, Silva WM, Tavares GC, et al. Mutation of the Surface Layer Protein SlpB Has Pleiotropic Effects in the Probiotic . Front Microbiol. 2018;9:1807doi: 10.3389/fmicb.2018.01807.
do Carmo, F. L. R., Silva, W. M., Tavares, G. C., Ibraim, I. C., Cordeiro, B. F., Oliveira, E. R., Rabah, H., Cauty, C., da Silva, S. H., Canário Viana, M. V., Caetano, A. C. B., Dos Santos, R. G., de Oliveira Carvalho, R. D., Jardin, J., Pereira, F. L., Folador, E. L., Le Loir, Y., Figueiredo, H. C. P., Jan, G., & Azevedo, V. (2018). Mutation of the Surface Layer Protein SlpB Has Pleiotropic Effects in the Probiotic . Frontiers in microbiology, 91807. https://doi.org/10.3389/fmicb.2018.01807
do Carmo, Fillipe L R, et al. "Mutation of the Surface Layer Protein SlpB Has Pleiotropic Effects in the Probiotic ." Frontiers in microbiology vol. 9 (2018): 1807. doi: https://doi.org/10.3389/fmicb.2018.01807
do Carmo FLR, Silva WM, Tavares GC, Ibraim IC, Cordeiro BF, Oliveira ER, Rabah H, Cauty C, da Silva SH, Canário Viana MV, Caetano ACB, Dos Santos RG, de Oliveira Carvalho RD, Jardin J, Pereira FL, Folador EL, Le Loir Y, Figueiredo HCP, Jan G, Azevedo V. Mutation of the Surface Layer Protein SlpB Has Pleiotropic Effects in the Probiotic . Front Microbiol. 2018 Aug 17;9:1807. doi: 10.3389/fmicb.2018.01807. eCollection 2018. PMID: 30174657; PMCID: PMC6107788.
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Concomitant myeloproliferative and lymphoproliferative neoplasms, distinct progenitors: A case report and review of the literature.

Molecular and clinical oncology

Mousinho F, Santos PSE, Azevedo AP, Pereira JM, Lemos R, Matos S, Viana JF, Lima F.
PMID: 30155258
Mol Clin Oncol. 2018 Sep;9(3):347-349. doi: 10.3892/mco.2018.1682. Epub 2018 Jul 19.

Patients with a Philadelphia chromosome-negative myeloproliferative neoplasm may develop a lymphoproliferative disorder; however, the clinical and molecular determinants and the chronological onset of the two events remain unknown. We herein report the case of a 64-year-old man with concomitant...

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Mousinho F, Santos PSE, Azevedo AP, et al. Concomitant myeloproliferative and lymphoproliferative neoplasms, distinct progenitors: A case report and review of the literature. Mol Clin Oncol. 2018;9(3):347-349doi: 10.3892/mco.2018.1682.
Mousinho, F., Santos, P. S. E., Azevedo, A. P., Pereira, J. M., Lemos, R., Matos, S., Viana, J. F., & Lima, F. (2018). Concomitant myeloproliferative and lymphoproliferative neoplasms, distinct progenitors: A case report and review of the literature. Molecular and clinical oncology, 9(3), 347-349. https://doi.org/10.3892/mco.2018.1682
Mousinho, Filipa, et al. "Concomitant myeloproliferative and lymphoproliferative neoplasms, distinct progenitors: A case report and review of the literature." Molecular and clinical oncology vol. 9,3 (2018): 347-349. doi: https://doi.org/10.3892/mco.2018.1682
Mousinho F, Santos PSE, Azevedo AP, Pereira JM, Lemos R, Matos S, Viana JF, Lima F. Concomitant myeloproliferative and lymphoproliferative neoplasms, distinct progenitors: A case report and review of the literature. Mol Clin Oncol. 2018 Sep;9(3):347-349. doi: 10.3892/mco.2018.1682. Epub 2018 Jul 19. PMID: 30155258; PMCID: PMC6109675.
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