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Showing 13 to 24 of 200 entries
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Low-loss Ge-rich Si0.2Ge0.8 waveguides for mid-infrared photonics.

Optics letters

Ramirez JM, Vakarin V, Gilles C, Frigerio J, Ballabio A, Chaisakul P, Roux XL, Alonso-Ramos C, Maisons G, Vivien L, Carras M, Isella G, Marris-Morini D.
PMID: 28059186
Opt Lett. 2017 Jan 01;42(1):105-108. doi: 10.1364/OL.42.000105.

We demonstrate low-loss Ge-rich Si0.2Ge0.8 waveguides on Si1-xGex (x from 0 to 0.79) graded substrates operating in the mid-infrared wavelength range at λ=4.6  μm. Propagation losses as low as (1.5±0.5)dB/cm and (2±0.5)dB/cm were measured for the quasi-TE and quasi-TM...

The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells.

Human molecular genetics

Palmisano I, Bagnato P, Palmigiano A, Innamorati G, Rotondo G, Altimare D, Venturi C, Sviderskaya EV, Piccirillo R, Coppola M, Marigo V, Incerti B, Ballabio A, Surace EM, Tacchetti C, Bennett DC, Schiaffino MV.
PMID: 28854565
Hum Mol Genet. 2017 Aug 01;26(15):3028-3029. doi: 10.1093/hmg/ddx131.

No abstract available.

Anorectal gastrointestinal stromal tumor: a case report and literature review.

Case reports in gastrointestinal medicine

Singhal S, Singhal A, Tugnait R, Varghese V, Tiwari B, Arora PK, Malik P, Bharali MD, Dhuria AS, Chauhan P, Singh C, Ballani A, Panwar V.
PMID: 23585972
Case Rep Gastrointest Med. 2013;2013:934875. doi: 10.1155/2013/934875. Epub 2013 Mar 25.

Gastrointestinal stromal tumors or "GIST" are mesenchymal neoplasms expressing KIT(CD117) tyrosine kinase and showing the presence of activating mutations in KIT or PDGFR α (platelet-derived growth factor alpha). GIST of anal canal is an extremely rare tumor, accounting for...

Characterization of integrated waveguides by atomic-force-microscopy-assisted mid-infrared imaging and spectroscopy.

Optics express

Gallacher K, Millar RW, Paul DJ, Frigerio J, Ballabio A, Isella G, Rusconi F, Biagioni P, Giliberti V, Sorgi A, Baldassarre L, Ortolani M.
PMID: 32752485
Opt Express. 2020 Jul 20;28(15):22186-22199. doi: 10.1364/OE.393748.

A novel spectroscopy technique to enable the rapid characterization of discrete mid-infrared integrated photonic waveguides is demonstrated. The technique utilizes lithography patterned polymer blocks that absorb light strongly within the molecular fingerprint region. These act as integrated waveguide detectors...

Ga metal nanoparticle-GaAs quantum molecule complexes for terahertz generation.

Nanotechnology

Bietti S, Basset FB, Scarpellini D, Fedorov A, Ballabio A, Esposito L, Elborg M, Kuroda T, Nemcsics Á, Tóth L, Manzoni C, Vozzi C, Sanguinetti S.
PMID: 29911655
Nanotechnology. 2018 Sep 07;29(36):365602. doi: 10.1088/1361-6528/aacd20. Epub 2018 Jun 18.

A hybrid metal-semiconductor nanosystem for the generation of THz radiation, based on the fabrication of GaAs quantum molecules-Ga metal nanoparticles complexes through a self assembly approach, is proposed. The role of the growth parameters, the substrate temperature, the Ga...

Usefulness of sleep events detection using a wrist worn peripheral arterial tone signal device (WatchPAT™) in a population at low risk of obstructive sleep apnea.

Journal of sleep research

Tondo P, Drigo R, Scioscia G, Ballarin A, Rossi E, Floriani AF, Pauletti A, Foschino Barbaro MP, Lacedonia D.
PMID: 33845515
J Sleep Res. 2021 Dec;30(6):e13352. doi: 10.1111/jsr.13352. Epub 2021 Apr 12.

Due to the high prevalence of obstructive sleep apnea (OSA), it is recommended to use in-laboratory polysomnography (PSG) or a home sleep apnea test (HSAT) in uncomplicated adult subjects at high risk of OSA. The aims of the present...

A lysosome-targeted DNA nanodevice selectively targets macrophages to attenuate tumours.

Nature nanotechnology

Cui C, Chakraborty K, Tang XA, Schoenfelt KQ, Hoffman A, Blank A, McBeth B, Pulliam N, Reardon CA, Kulkarni SA, Vaisar T, Ballabio A, Krishnan Y, Becker L.
PMID: 34764452
Nat Nanotechnol. 2021 Dec;16(12):1394-1402. doi: 10.1038/s41565-021-00988-z. Epub 2021 Nov 11.

Activating CD8

Culturing and Scaling up Stem Cells of Dental Pulp Origin Using Microcarriers.

Polymers

Földes A, Reider H, Varga A, Nagy KS, Perczel-Kovach K, Kis-Petik K, DenBesten P, Ballagi A, Varga G.
PMID: 34833250
Polymers (Basel). 2021 Nov 15;13(22). doi: 10.3390/polym13223951.

Ectomesenchymal stem cells derived from the dental pulp are of neural crest origin, and as such are promising sources for cell therapy and tissue engineering. For safe upscaling of these cells, microcarrier-based culturing under dynamic conditions is a promising...

TFEB regulates lysosomal exocytosis of tau and its loss of function exacerbates tau pathology and spreading.

Molecular psychiatry

Xu Y, Du S, Marsh JA, Horie K, Sato C, Ballabio A, Karch CM, Holtzman DM, Zheng H.
PMID: 32366951
Mol Psychiatry. 2021 Oct;26(10):5925-5939. doi: 10.1038/s41380-020-0738-0. Epub 2020 May 04.

Neurofibrillary tangles (NFTs) composed of hyperphosphorylated and misfolded tau protein are a pathological hallmark of Alzheimer's disease and other tauopathy conditions. Tau is predominantly an intraneuronal protein but is also secreted in physiological and pathological conditions. The extracellular tau...

Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling.

Acta neuropathologica

Nazio F, Po A, Abballe L, Ballabio C, Diomedi Camassei F, Bordi M, Camera A, Caruso S, Caruana I, Pezzullo M, Ferraina C, Milletti G, Gianesello M, Reddel S, De Luca CD, Ceglie D, Marinelli S, Campello S, Papaleo E, Miele E, Cacchione A, Carai A, Vinci M, Velardi E, De Angelis B, Tiberi L, Quintarelli C, Mastronuzzi A, Ferretti E, Locatelli F, Cecconi F.
PMID: 34302498
Acta Neuropathol. 2021 Sep;142(3):537-564. doi: 10.1007/s00401-021-02347-7. Epub 2021 Jul 24.

Medulloblastoma (MB) is a childhood malignant brain tumour comprising four main subgroups characterized by different genetic alterations and rate of mortality. Among MB subgroups, patients with enhanced levels of the c-MYC oncogene (MB

Parsimonious Optimization of Multitask Neural Network Hyperparameters.

Molecules (Basel, Switzerland)

Valsecchi C, Consonni V, Todeschini R, Orlandi ME, Gosetti F, Ballabio D.
PMID: 34885837
Molecules. 2021 Nov 30;26(23). doi: 10.3390/molecules26237254.

Neural networks are rapidly gaining popularity in chemical modeling and Quantitative Structure-Activity Relationship (QSAR) thanks to their ability to handle multitask problems. However, outcomes of neural networks depend on the tuning of several hyperparameters, whose small variations can often...

Emapalumab in primary haemophagocytic lymphohistiocytosis and the pathogenic role of interferon gamma: A pharmacometric model-based approach.

British journal of clinical pharmacology

Jacqmin P, Laveille C, Snoeck E, Jordan MB, Locatelli F, Ballabio M, de Min C.
PMID: 34935183
Br J Clin Pharmacol. 2021 Oct 28; doi: 10.1111/bcp.15133. Epub 2021 Oct 28.

AIM: Primary haemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening, hyperinflammatory syndrome generally occurring in early childhood. The monoclonal antibody emapalumab binds and neutralises interferon γ (IFNγ). This study aimed to determine an emapalumab dosing regimen when traditional dose-finding approaches...

Showing 13 to 24 of 200 entries