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Showing 325 to 331 of 331 entries
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Trajectory of Viral RNA Load Among Persons With Incident SARS-CoV-2 G614 Infection (Wuhan Strain) in Association With COVID-19 Symptom Onset and Severity.

JAMA network open

Stankiewicz Karita HC, Dong TQ, Johnston C, Neuzil KM, Paasche-Orlow MK, Kissinger PJ, Bershteyn A, Thorpe LE, Deming M, Kottkamp A, Laufer M, Landovitz RJ, Luk A, Hoffman R, Roychoudhury P, Magaret CA, Greninger AL, Huang ML, Jerome KR, Wener M, Celum C, Chu HY, Baeten JM, Wald A, Barnabas RV, Brown ER.
PMID: 35006245
JAMA Netw Open. 2022 Jan 04;5(1):e2142796. doi: 10.1001/jamanetworkopen.2021.42796.

IMPORTANCE: The SARS-CoV-2 viral trajectory has not been well characterized in incident infections. These data are needed to inform natural history, prevention practices, and therapeutic development.OBJECTIVE: To characterize early SARS-CoV-2 viral RNA load (hereafter referred to as viral load)...

A semi-Markov model comparing the lifetime cost-effectiveness of mesh prophylaxis to prevent parastomal hernia in patients undergoing end colostomy creation for rectal cancer.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

Mohiuddin S, Reeves BC, Smart NJ, Hollingworth W.
PMID: 34331840
Colorectal Dis. 2021 Nov;23(11):2967-2979. doi: 10.1111/codi.15848. Epub 2021 Aug 12.

AIM: Parastomal hernia (PSH) is a common problem following colostomy. Using prophylactic mesh during end colostomy creation may reduce PSH incidence, but concerns exist regarding the optimal type of mesh, potential long-term complications, and cost-effectiveness of its use. We...

Compression of amorphous solid dispersions prepared by hot-melt extrusion, spray drying and vacuum drum drying.

International journal of pharmaceutics: X

Schönfeld BV, Westedt U, Wagner KG.
PMID: 34877525
Int J Pharm X. 2021 Nov 03;3:100102. doi: 10.1016/j.ijpx.2021.100102. eCollection 2021 Dec.

The present study explored vacuum drum drying (VDD) as an alternative technology for amorphous solid dispersions (ASDs) manufacture compared to hot-melt extrusion (HME) and spray drying (SD) focusing on downstream processability (powder properties, compression behavior and tablet performance). Ritonavir...

Effects of Selenium Supplementation on Sperm Parameters and DNA-Fragmentation Rate in Patients with Chronic Autoimmune Thyroiditis.

Journal of clinical medicine

Cannarella R, Condorelli RA, Calogero AE, Bagnara V, Aversa A, Greco EA, Brunetti A, La Vignera S.
PMID: 34442049
J Clin Med. 2021 Aug 23;10(16). doi: 10.3390/jcm10163755.

BACKGROUND: Selenium (Se) is an essential component of selenoenzymes, which have catalytic and antioxidant functions. A low Se status has been reported in patients with chronic autoimmune thyroiditis (AT) who benefit from Se supplementation. The role of Se in...

Oedipality and oedipal complexes reconsidered: On the incest taboo as key to the universality of the human condition.

The International journal of psycho-analysis

Barratt BB.
PMID: 33945713
Int J Psychoanal. 2019 Feb;100(1):7-31. doi: 10.1080/00207578.2018.1489704.

Oedipality is generally understood as the individual's journey through eroticized attachments with those performing maternal and paternal functions. This has evoked understandable resistance, and also unnecessary, yet sometimes scholarly, opposition. This paper briefly reviews the voluminous literature on oedipality,...

The exploration of hot nuclear matter.

Science (New York, N.Y.)

Jacak BV, Müller B.
PMID: 22822143
Science. 2012 Jul 20;337(6092):310-4. doi: 10.1126/science.1215901.

When nuclear matter is heated beyond 2 trillion degrees, it becomes a strongly coupled plasma of quarks and gluons. Experiments using highly energetic collisions between heavy nuclei have revealed that this new state of matter is a nearly ideal,...

Investments in the future of behavioral science: The University of California, San Francisco, Visiting Professors Program.

Dolcini MMargaret, Reznick OlgaAGrinstead, Marín BarbaraV.
UIID-AD: 1641
2009;99. doi: 10.2105/AJPH.2007.121301.

A need exists for the promotion of diversity in the scientific workforce to better address health disparities. In response to this need, funding agencies and institutions have developed programs to encourage ethnic-minority and early-career scientists to pursue research careers....

Showing 325 to 331 of 331 entries