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Showing 25 to 36 of 112 entries
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The allergenic activity and clinical impact of individual IgE-antibody binding molecules from indoor allergen sources.

The World Allergy Organization journal

Caraballo L, Valenta R, Puerta L, Pomés A, Zakzuk J, Fernandez-Caldas E, Acevedo N, Sanchez-Borges M, Ansotegui I, Zhang L, van Hage M, Abel-Fernández E, Karla Arruda L, Vrtala S, Curin M, Gronlund H, Karsonova A, Kilimajer J, Riabova K, Trifonova D, Karaulov A.
PMID: 32373267
World Allergy Organ J. 2020 Apr 29;13(5):100118. doi: 10.1016/j.waojou.2020.100118. eCollection 2020 May.

A large number of allergens have been discovered but we know little about their potential to induce inflammation (allergenic activity) and symptoms. Nowadays, the clinical importance of allergens is determined by the frequency and intensity of their IgE antibody...

Breast cancer glycan biomarkers: their link to tumour cell metabolism and their perspectives in clinical practice.

Expert review of proteomics

Bertok T, Pinkova Gajdosova V, Bertokova A, Svecova N, Kasak P, Tkac J.
PMID: 34711108
Expert Rev Proteomics. 2021 Oct;18(10):881-910. doi: 10.1080/14789450.2021.1996231. Epub 2021 Nov 18.

INTRODUCTION: Breast cancer (BCa) is the most common cancer type diagnosed in women and 5AREAS COVERED: In this review paper, we aim to cover some basic aspects regarding cellular metabolism and signalling in BCa behind altered glycosylation. We also...

TNFRSF12A and CD38 Contribute to a Vicious Circle for Chronic Obstructive Pulmonary Disease by Engaging Senescence Pathways.

Frontiers in cell and developmental biology

Dong Y, Cao H, Cao R, Baranova A.
PMID: 32537452
Front Cell Dev Biol. 2020 May 27;8:330. doi: 10.3389/fcell.2020.00330. eCollection 2020.

Pathogenesis of chronic obstructive pulmonary disease (COPD) is dependent on chronic inflammation and is hypothesized to represent organ-specific senescence phenotype. Identification of senescence-associated gene drivers for the development of COPD is warranted. By employing automated pipeline, we have compiled...

Patient-specific apparent diffusion maps used to model nutrient availability in degenerated intervertebral discs.

JOR spine

Shalash W, Ahrens SR, Bardonova LA, Byvaltsev VA, Giers MB.
PMID: 35005445
JOR Spine. 2021 Nov 22;4(4):e1179. doi: 10.1002/jsp2.1179. eCollection 2021 Dec.

INTRODUCTION: In this study, magnetic resonance imaging data was used to (1) model IVD-specific gradients of glucose, oxygen, lactate, and pH; and (2) investigate possible effects of covariate factors (i.e., disc geometry, and mean apparent diffusion coefficient values) on...

Whisker trimming during infanthood modifies the development of spike-wave discharges and behavioral sequences in IntelliCage impulsivity paradigm in adult WAG/Rij rats.

Behavioural brain research

Esmaeili A, Antonova A, Sitnikova E, Smirnov K.
PMID: 34648796
Behav Brain Res. 2022 Feb 10;418:113627. doi: 10.1016/j.bbr.2021.113627. Epub 2021 Oct 11.

Whisker system in rats undergoes rapid development during the first postnatal weeks. Neonatal whisker trimming increases excitability in the somatosensory cortex and affects exploratory behavior at adult ages. WAG/Rij rats are genetically predisposed to develop absence seizures in adulthood,...

Shared Genetic Liability and Causal Associations Between Major Depressive Disorder and Cardiovascular Diseases.

Frontiers in cardiovascular medicine

Zhang F, Cao H, Baranova A.
PMID: 34859065
Front Cardiovasc Med. 2021 Nov 11;8:735136. doi: 10.3389/fcvm.2021.735136. eCollection 2021.

Major depressive disorder (MDD) is phenotypically associated with cardiovascular diseases (CVD). We aim to investigate mechanisms underlying relationships between MDD and CVD in the context of shared genetic variations. Polygenic overlap analysis was used to test genetic correlation and...

Detection of .

Food and waterborne parasitology

Bartosova B, Koudela B, Slana I.
PMID: 34169159
Food Waterborne Parasitol. 2021 Apr 26;23:e00124. doi: 10.1016/j.fawpar.2021.e00124. eCollection 2021 Jun.

The current trend for a healthy lifestyle corresponds with a healthy diet, which is associated with regular and frequent consumption of raw fruit and vegetables. However, consumption of ready-to-eat (RTE) food without heat treatment or sufficient washing may pose...

Shared genetic liability and causal effects between major depressive disorder and insomnia.

Human molecular genetics

Baranova A, Cao H, Zhang F.
PMID: 34761251
Hum Mol Genet. 2021 Nov 11; doi: 10.1093/hmg/ddab328. Epub 2021 Nov 11.

Deciphering the genetic relationships between major depressive disorder (MDD) and insomnia may facilitate understanding biological mechanisms as well as inform more effective treatment regimens for these conditions. Here we attempted to investigate mechanisms underlying relationships between MDD and insomnia...

Absolute Quantification of the Central Carbon Metabolome in Eight Commonly Applied Prokaryotic and Eukaryotic Model Systems.

Metabolites

Røst LM, Brekke Thorfinnsdottir L, Kumar K, Fuchino K, Eide Langørgen I, Bartosova Z, Kristiansen KA, Bruheim P.
PMID: 32093075
Metabolites. 2020 Feb 19;10(2). doi: 10.3390/metabo10020074.

Absolute quantification of intracellular metabolite pools is a prerequisite for modeling and in-depth biological interpretation of metabolomics data. It is the final step of an elaborate metabolomics workflow, with challenges associated with all steps-from sampling to quantifying the physicochemically...

Correction: Multi-trait analysis for genome-wide association study of five psychiatric disorders.

Translational psychiatry

Wu Y, Cao H, Baranova A, Huang H, Li S, Cai L, Rao S, Dai M, Xie M, Dou Y, Hao Q, Zhu L, Zhang X, Yao Y, Zhang F, Xu M, Wang Q.
PMID: 32665544
Transl Psychiatry. 2020 Jul 14;10(1):234. doi: 10.1038/s41398-020-00924-0.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

End-User Feedback on a Low-Cost Portable Air Quality Sensor System-Are We There Yet?.

Sensors (Basel, Switzerland)

Robinson JA, Kocman D, Horvat M, Bartonova A.
PMID: 30400374
Sensors (Basel). 2018 Nov 04;18(11). doi: 10.3390/s18113768.

Low-cost sensors are a current trend in citizen science projects that focus on air quality. Until now, devices incorporating such sensors have been tested primarily for their technical capabilities and limitations, whereas their usability and acceptability amongst the public...

Analysis of optical recording stability using wavelet entropy of action potentials.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference

Provaznik I, Bardonova J, Novakova M, Vesely Z, Blaha M.
PMID: 17271690
Conf Proc IEEE Eng Med Biol Soc. 2004;2006:377-9. doi: 10.1109/IEMBS.2004.1403172.

A method based on wavelet entropy is presented for analysis of optically recorded action potentials to assess stability of the experiment. The action potentials are recorded using fluorescent voltage-sensitive dye di-4-ANEPPS by optical means. The acquired signals are preprocessed...

Showing 25 to 36 of 112 entries