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Showing 181 to 189 of 189 entries
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Does experiencing inattentional blindness for crime influence eyewitness recall?.

Memory (Hove, England)

Cullen HJ, Paterson HM, van Golde C.
PMID: 34783643
Memory. 2021 Nov 16;1-11. doi: 10.1080/09658211.2021.2002906. Epub 2021 Nov 16.

Witnesses may not notice crimes occurring when their attention is elsewhere, which may affect their memory. In this study, 174 participants completed an attention-demanding task while viewing a video containing an assault. Whether participants noticed the assault or experienced...

Slip/Stick Viscosity Models of Nanoconfined Liquids: Solvent-Dependent Rotation in Metal-Organic Frameworks.

The Journal of organic chemistry

Jellen MJ, Jiang X, Benders S, Adams A, Garcia-Garibay MA.
PMID: 34878273
J Org Chem. 2021 Dec 08; doi: 10.1021/acs.joc.1c02218. Epub 2021 Dec 08.

Artificial molecular machines are expected to operate in environments where viscous forces impact molecules significantly. With that, it is well-known that solvent behaviors dramatically change upon confinement into limited spaces as compared to bulk solvents. In this study, we...

pH-responsive oleic acid based nanocarriers: Melanoma treatment strategies.

International journal of pharmaceutics

Rinaldi F, Forte J, Pontecorvi G, Hanieh PN, Carè A, Bellenghi M, Tirelli V, Ammendolia MG, Mattia G, Marianecci C, Puglisi R, Carafa M.
PMID: 34923052
Int J Pharm. 2021 Dec 16;613:121391. doi: 10.1016/j.ijpharm.2021.121391. Epub 2021 Dec 16.

Numerous clinical observations indicate that, despite novel therapeutic approaches, a high percentage of melanoma patients is non-responder or suffers of severe drug-related toxicity. To overcome these problems, we considered the option of designing, preparing and characterizing nanoemulsions and niosomes...

Rare deleterious de novo missense variants in Rnf2/Ring2 are associated with a neurodevelopmental disorder with unique clinical features.

Human molecular genetics

Luo X, Schoch K, Jangam SV, Bhavana VH, Graves HK, Kansagra S, Jasien JM, Stong N, Keren B, Mignot C, Ravelli C, Bellen HJ, Wangler MF, Shashi V, Yamamoto S.
PMID: 33864376
Hum Mol Genet. 2021 Jun 26;30(14):1283-1292. doi: 10.1093/hmg/ddab110.

The Polycomb group (PcG) gene RNF2 (RING2) encodes a catalytic subunit of the Polycomb repressive complex 1 (PRC1), an evolutionarily conserved machinery that post-translationally modifies chromatin to maintain epigenetic transcriptional repressive states of target genes including Hox genes. Here,...

Enhanced Gearing Fidelity Achieved Through Macrocyclization of a Solvated Molecular Spur Gear.

Journal of the American Chemical Society

Jellen MJ, Liepuoniute I, Jin M, Jones CG, Yang S, Jiang X, Nelson HM, Houk KN, Garcia-Garibay MA.
PMID: 33998231
J Am Chem Soc. 2021 May 26;143(20):7740-7747. doi: 10.1021/jacs.1c01885. Epub 2021 May 17.

Molecular spur gear dynamics with high gearing fidelity can be achieved through a careful selection of constituent molecular components that favorably position and maintain the two gears in a meshed configuration. Here, we report the synthesis of a new...

Property activity refinement of 2-anilino 4-amino substituted quinazolines as antimalarials with fast acting asexual parasite activity.

Bioorganic chemistry

Ashton TD, Ngo A, Favuzza P, Bullen HE, Gancheva MR, Romeo O, Parkyn Schneider M, Nguyen N, Steel RWJ, Duffy S, Lowes KN, Sabroux HJ, Avery VM, Boddey JA, Wilson DW, Cowman AF, Gilson PR, Sleebs BE.
PMID: 34689083
Bioorg Chem. 2021 Dec;117:105359. doi: 10.1016/j.bioorg.2021.105359. Epub 2021 Sep 21.

Malaria is a devastating disease caused by Plasmodium parasites. Emerging resistance against current antimalarial therapeutics has engendered the need to develop antimalarials with novel structural classes. We recently described the identification and initial optimization of the 2-anilino quinazoline antimalarial...

Context Matters: Social Psychological Factors That Underlie Academic Performance across Seven Institutions.

CBE life sciences education

Salehi S, Berk SA, Brunelli R, Cotner S, Creech C, Drake AG, Fagbodun S, Hall C, Hebert S, Hewlett J, James AC, Shuster M, St Juliana JR, Stovall DB, Whittington R, Zhong M, Ballen CJ.
PMID: 34767460
CBE Life Sci Educ. 2021 Dec;20(4):ar68. doi: 10.1187/cbe.21-01-0012.

To enhance equity and diversity in undergraduate biology, recent research in biology education focuses on best practices that reduce learning barriers for all students and improve academic performance. However, the majority of current research into student experiences in introductory...

Teaching the Tough Topics: Fostering Ideological Awareness through the Inclusion of Societally Impactful Topics in Introductory Biology.

CBE life sciences education

Beatty AE, Driessen EP, Gusler T, Ewell S, Grilliot A, Ballen CJ.
PMID: 34767458
CBE Life Sci Educ. 2021 Dec;20(4):ar67. doi: 10.1187/cbe.21-04-0100.

While science has profound social impacts, we often teach biology as removed from societally debated issues. Here, we address this gap in biology education through the implementation of novel materials that promote ideological awareness (IA). Using mixed-method analyses, we...

Enhancing diversity in undergraduate science: self-efficacy drives performance gains with active learning.

Ballen CJ, Wieman C, Salehi S, Searle JB, Zamudio KR.
UIID-AD: 4768
2017; doi: 10.1187/cbe.16-12-0344.

Efforts to retain underrepresented minority (URM) students in science, technology, engineering, and mathematics (STEM) have shown only limited success in higher education, due in part to a persistent achievement gap between students from historically underrepresented and well-represented backgrounds. To...

Showing 181 to 189 of 189 entries