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Showing 421 to 424 of 424 entries
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Neuronal VCP loss of function recapitulates FTLD-TDP pathology.

Cell reports

Wani A, Zhu J, Ulrich JD, Eteleeb A, Sauerbeck AD, Reitz SJ, Arhzaouy K, Ikenaga C, Yuede CM, Pittman SK, Wang F, Li S, Benitez BA, Cruchaga C, Kummer TT, Harari O, Chou TF, Schröder R, Clemen CS, Weihl CC, McLean R.
PMID: 34289347
Cell Rep. 2021 Jul 20;36(3):109399. doi: 10.1016/j.celrep.2021.109399.

The pathogenic mechanism by which dominant mutations in VCP cause multisystem proteinopathy (MSP), a rare neurodegenerative disease that presents as fronto-temporal lobar degeneration with TDP-43 inclusions (FTLD-TDP), remains unclear. To explore this, we inactivate VCP in murine postnatal forebrain...

Inhibitory control and obesity in adolescents: A prospective cohort study.

Appetite

Mayer MA, Catalani F, Fraire J, Deltetto N, Martín L, Beneitez A, Fischman D, Orden AB.
PMID: 35007663
Appetite. 2022 Jan 07;171:105910. doi: 10.1016/j.appet.2022.105910. Epub 2022 Jan 07.

INTRODUCTION: Inhibitory control (IC) is an executive function that plays a central role in the capability to control one's attention and behavior. Growing evidence suggests that deficits in IC are related to calorie consumption and obesity development. However, there...

Exome sequencing revealed PDE11A as a novel candidate gene for early-onset Alzheimer's disease.

Human molecular genetics

Qin W, Zhou A, Zuo X, Jia L, Li F, Wang Q, Li Y, Wei Y, Jin H, Cruchaga C, Benitez BA, Jia J.
PMID: 33835157
Hum Mol Genet. 2021 May 28;30(9):811-822. doi: 10.1093/hmg/ddab090.

To identify novel risk genes and better understand the molecular pathway underlying Alzheimer's disease (AD), whole-exome sequencing was performed in 215 early-onset AD (EOAD) patients and 255 unrelated healthy controls of Han Chinese ethnicity. Subsequent validation, computational annotation and...

Neuroimaging training among neuropsychologists: a survey of the state of current training and recommendations for trainees.

Benitez A, Hassenstab J, Bangen KJ.
UIID-AD: 2659
2014;28:600-13. doi: 10.1080/13854046.2013.854836.

Neuroimaging has gained widespread use in neuropsychological research and practice. However, there are neither established guidelines on how neuropsychologists might become competent researchers or consumers of neuroimaging data, nor any published studies describing the state of neuroimaging training among...

Showing 421 to 424 of 424 entries