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Showing 1165 to 1166 of 1166 entries
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KRAS G12C fragment screening renders new binding pockets.

Small GTPases

Mathieu M, Steier V, Fassy F, Delorme C, Papin D, Genet B, Duffieux F, Bertrand T, Delarbre L, Le-Borgne H, Parent A, Didier P, Marquette JP, Lowinski M, Houtmann J, Lamberton A, Debussche L, Alexey R.
PMID: 34558391
Small GTPases. 2022 Jan;13(1):225-238. doi: 10.1080/21541248.2021.1979360. Epub 2021 Sep 24.

KRAS genes belong to the most frequently mutated family of oncogenes in cancer. The G12C mutation, found in a third of lung, half of colorectal and pancreatic cancer cases, is believed to be responsible for a substantial number of...

Dietary Mediators of the Genetic Susceptibility to Obesity-Results from the Quebec Family Study.

The Journal of nutrition

Jacob R, Bertrand C, Llewellyn C, Couture C, Labonté MÈ, Tremblay A, Bouchard C, Drapeau V, Pérusse L.
PMID: 34610139
J Nutr. 2022 Jan 11;152(1):49-58. doi: 10.1093/jn/nxab356.

BACKGROUND: Recent studies showed that eating behaviors such as disinhibition, emotional and external eating, and snacking mediate genetic susceptibility to obesity. It remains unknown if diet quality and intake of specific food groups also mediate the genetic susceptibility to...

Showing 1165 to 1166 of 1166 entries