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Showing 25 to 36 of 200 entries
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ZBTB32 performs crosstalk with the glucocorticoid receptor and is crucial in glucocorticoid responses to starvation.

iScience

Van Wyngene L, Vanderhaeghen T, Petta I, Timmermans S, Corbeels K, Van der Schueren B, Vandewalle J, Van Looveren K, Wallaeys C, Eggermont M, Dewaele S, Catrysse L, van Loo G, Beyaert R, Vangoitsenhoven R, Nakayama T, Tavernier J, De Bosscher K, Libert C.
PMID: 34337361
iScience. 2021 Jun 28;24(7):102790. doi: 10.1016/j.isci.2021.102790. eCollection 2021 Jul 23.

The hypothalamic-pituitary-adrenal (HPA) axis forms a complex neuroendocrine system that regulates the body's response to stress such as starvation. In contrast with the glucocorticoid receptor (GR), Zinc finger and BTB domain containing 32 (ZBTB32) is a transcription factor with...

Response of an Afro-Palearctic bird migrant to glaciation cycles.

Proceedings of the National Academy of Sciences of the United States of America

Thorup K, Pedersen L, da Fonseca RR, Naimi B, Nogués-Bravo D, Krapp M, Manica A, Willemoes M, Sjöberg S, Feng S, Chen G, Rey-Iglesia A, Campos PF, Beyer R, Araújo MB, Hansen AJ, Zhang G, Tøttrup AP, Rahbek C.
PMID: 34949638
Proc Natl Acad Sci U S A. 2021 Dec 28;118(52). doi: 10.1073/pnas.2023836118. Epub 2021 Dec 23.

Migration allows animals to exploit spatially separated and seasonally available resources at a continental to global scale. However, responding to global climatic changes might prove challenging, especially for long-distance intercontinental migrants. During glacial periods, when conditions became too harsh...

Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice.

The Journal of experimental medicine

Pieters T, T'Sas S, Vanhee S, Almeida A, Driege Y, Roels J, Van Loocke W, Daneels W, Baens M, Marchand A, Van Trimpont M, Matthijssens F, Morscio J, Lemeire K, Lintermans B, Reunes L, Chaltin P, Offner F, Van Dorpe J, Hochepied T, Berx G, Beyaert R, Staal J, Van Vlierberghe P, Goossens S.
PMID: 34406363
J Exp Med. 2021 Oct 04;218(10). doi: 10.1084/jem.20202280. Epub 2021 Aug 18.

Mantle cell lymphoma (MCL) is an aggressive B cell lymphoma with poor long-term overall survival. Currently, MCL research and development of potential cures is hampered by the lack of good in vivo models. MCL is characterized by recurrent translocations...

Bonding properties of third-generation zirconia CAD-CAM blocks for monolithic restorations to composite and resin-modified glass-ionomer cements.

Journal of prosthodontic research

Eldafrawy M, Bekaert S, Nguyen JF, Sadoun M, Mainjot A.
PMID: 34853211
J Prosthodont Res. 2021 Dec 02; doi: 10.2186/jpr.JPR_D_21_00044. Epub 2021 Dec 02.

PURPOSE: To compare the interfacial fracture toughness (IFT) of two MDP-based composite cements and a resin-modified glass-ionomer cement (RMGIC) with third-generation zirconia CAD-CAM restorations using two different airborne-particle abrasion (AB) pressures.METHODS: Blocks were cut into prisms (n=60), split and...

Reprogramming of glucocorticoid receptor function by hypoxia.

EMBO reports

Vanderhaeghen T, Timmermans S, Watts D, Paakinaho V, Eggermont M, Vandewalle J, Wallaeys C, Van Wyngene L, Van Looveren K, Nuyttens L, Dewaele S, Vanden Berghe J, Lemeire K, De Backer J, Dirkx L, Vanden Berghe W, Caljon G, Ghesquière B, De Bosscher K, Wielockx B, Palvimo JJ, Beyaert R, Libert C.
PMID: 34699114
EMBO Rep. 2022 Jan 05;23(1):e53083. doi: 10.15252/embr.202153083. Epub 2021 Oct 26.

Here, we investigate the impact of hypoxia on the hepatic response of glucocorticoid receptor (GR) to dexamethasone (DEX) in mice via RNA-sequencing. Hypoxia causes three types of reprogramming of GR: (i) much weaker induction of classical GR-responsive genes by...

Postural Control in Lyric Singers.

Journal of voice : official journal of the Voice Foundation

Peultier-Celli L, Audouin M, Beyaert C, Perrin P.
PMID: 32456837
J Voice. 2022 Jan;36(1):141.e11-141.e17. doi: 10.1016/j.jvoice.2020.04.019. Epub 2020 May 24.

BACKGROUND: Singers are unique musicians because they use their whole body as a musical instrument. Posture and proprioception are key components for a robust and healthy voice.OBJECTIVE: This study aimed to analyze the postural control of lyric singers in...

Analysis of T cells in mouse lymphoid tissue and blood with flow cytometry.

STAR protocols

Skordos I, Demeyer A, Beyaert R.
PMID: 33665631
STAR Protoc. 2021 Feb 20;2(1):100351. doi: 10.1016/j.xpro.2021.100351. eCollection 2021 Mar 19.

T cells play a key role in adaptive immunity. Defects in specific T cell receptors or signaling proteins can alter their frequency and activation status, which may be associated with immune disease or cancer. Monitoring of T cell frequency...

Involving society in science: Reflections on meaningful and impactful stakeholder engagement in fundamental research.

EMBO reports

Garrison H, Agostinho M, Alvarez L, Bekaert S, Bengtsson L, Broglio E, Couso D, Araújo Gomes R, Ingram Z, Martinez E, Mena AL, Nickel D, Norman M, Pinheiro I, Solís-Mateos M, Bertero MG.
PMID: 34734669
EMBO Rep. 2021 Nov 04;22(11):e54000. doi: 10.15252/embr.202154000.

Open Science calls for transparent science and involvement of various stakeholders. Here are examples of and advice for meaningful stakeholder engagement.

The impact of androgen deprivation therapy on bone mineral density in men treated for paraphilic disorder: A retrospective cohort study.

Andrology

De Landtsheer A, Bekaert L, David K, Marcq P, Jeandarme I, Decallonne B, Antonio L, Vanderschueren D.
PMID: 34914863
Andrology. 2021 Dec 16; doi: 10.1111/andr.13142. Epub 2021 Dec 16.

BACKGROUND: Guidelines suggest treating men with paraphilic disorder with androgen-deprivation therapy (ADT). However, little evidence is available about the long-term impact on bone loss and how to manage this adverse event.OBJECTIVES: The aim of this study is to assess...

Range Sizes of the World's Mammals, Birds, and Amphibians from the Mid-Holocene to the Industrial Period.

Animals : an open access journal from MDPI

Beyer R, Manica A.
PMID: 34944335
Animals (Basel). 2021 Dec 15;11(12). doi: 10.3390/ani11123561.

Anthropogenic land use and climate change in the Industrial age have had substantial impacts on the geographic ranges of the world's terrestrial animal species. How do these impacts compare against those in the millennia preceding the Industrial era? Here,...

Hippocampal sclerosis and epilepsy surgery in neurofibromatosis type 1: case report of a 3-year-old child explored by SEEG and review of the literature.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Sculier C, Taussig D, Aeby A, Blustajn J, Bekaert O, Fohlen M.
PMID: 34508273
Childs Nerv Syst. 2021 Sep 10; doi: 10.1007/s00381-021-05343-0. Epub 2021 Sep 10.

PURPOSE: Epilepsy associated with neurofibromatosis type 1 (NF1) is infrequent and usually controlled with anti-epileptic drugs. However, in some drug-resistant patients a presurgical evaluation should be considered. Hippocampal sclerosis (HS) is one of the rare causes of epilepsy in...

Involving society in science: Reflections on meaningful and impactful stakeholder engagement in fundamental research.

EMBO reports

Garrison H, Agostinho M, Alvarez L, Bekaert S, Bengtsson L, Broglio E, Couso D, Araújo Gomes R, Ingram Z, Martinez E, Mena AL, Nickel D, Norman M, Pinheiro I, Solís-Mateos M, Bertero MG.
PMID: 34734669
EMBO Rep. 2021 Nov 04;22(11):e54000. doi: 10.15252/embr.202154000.

Open Science calls for transparent science and involvement of various stakeholders. Here are examples of and advice for meaningful stakeholder engagement.

Showing 25 to 36 of 200 entries