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Showing 25 to 36 of 171 entries
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Inferring modes of evolution from colorectal cancer with residual polyp of origin.

Oncotarget

Kim M, Druliner BR, Vasmatzis N, Bae T, Chia N, Abyzov A, Boardman LA.
PMID: 29467928
Oncotarget. 2017 Dec 26;9(6):6780-6792. doi: 10.18632/oncotarget.23687. eCollection 2018 Jan 23.

Besides the classical evolutionary model of colorectal cancer (CRC) defined by the stepwise accumulation of mutations in which normal epithelium transforms through an intermediary polyp stage to cancer, a few studies have proposed alternative modes of evolution (MOE): early...

Multisoliton emission from a nonlinear waveguide.

Physical review. A, General physics

Boardman AD, Moloney JV, Seaton CT, Stegeman GI, Wright EM.
PMID: 9897804
Phys Rev A Gen Phys. 1986 Nov;34(5):4442-4444. doi: 10.1103/physreva.34.4442.

No abstract available.

Early life stress and LPS interact to modify the mouse cortical transcriptome in the neonatal period.

Brain, behavior, & immunity - health

Fitzgerald E, Boardman JP, Drake AJ.
PMID: 34589738
Brain Behav Immun Health. 2021 Feb 13;13:100219. doi: 10.1016/j.bbih.2021.100219. eCollection 2021 May.

INTRODUCTION: Preterm birth (PTB) is closely associated with atypical cerebral cortical development and cognitive impairment. Early exposure to extrauterine life often results in atypical environmental and biological experiences that co-occur, including early life stress (ELS) and systemic inflammation. Understanding...

Altered hypothalamic DNA methylation and stress-induced hyperactivity following early life stress.

Epigenetics & chromatin

Fitzgerald E, Sinton MC, Wernig-Zorc S, Morton NM, Holmes MC, Boardman JP, Drake AJ.
PMID: 34193254
Epigenetics Chromatin. 2021 Jun 30;14(1):31. doi: 10.1186/s13072-021-00405-8.

Exposure to early life stress (ELS) during childhood or prenatally increases the risk of future psychiatric disorders. The effect of stress exposure during the neonatal period is less well understood. In preterm infants, exposure to invasive procedures is associated...

Tracing the potential of networks to improve community cancer care: an in-depth single case study.

Implementation science communications

Ridgeway JL, Boardman LA, Griffin JM, Beebe TJ.
PMID: 34433489
Implement Sci Commun. 2021 Aug 25;2(1):92. doi: 10.1186/s43058-021-00190-1.

BACKGROUND: Despite overall declines in cancer mortality in the USA over the past three decades, many patients in community settings fail to receive evidence-based cancer care. Networks that link academic medical centers (AMCs) and community providers may reduce disparities...

On student unrest.

Annals of internal medicine

Boardman DW.
PMID: 5552128
Ann Intern Med. 1971 Mar;74(3):454. doi: 10.7326/0003-4819-74-3-454_2.

No abstract available.

Effect of Vitamin D Supplementation on Outcomes in People With Early Psychosis: The DFEND Randomized Clinical Trial.

JAMA network open

Gaughran F, Stringer D, Wojewodka G, Landau S, Smith S, Gardner-Sood P, Taylor D, Jordan H, Whiskey E, Krivoy A, Ciufolini S, Stubbs B, Casetta C, Williams J, Moore S, Allen L, Rathod S, Boardman A, Khalifa R, Firdosi M, McGuire P, Berk M, McGrath J.
PMID: 34962559
JAMA Netw Open. 2021 Dec 01;4(12):e2140858. doi: 10.1001/jamanetworkopen.2021.40858.

IMPORTANCE: People with psychotic disorders have an increased risk of vitamin D deficiency, which is evident during first-episode psychosis (FEP) and associated with unfavorable mental and physical health outcomes.OBJECTIVE: To examine whether vitamin D supplementation contributes to improved clinical...

Effect of Vitamin D Supplementation on Outcomes in People With Early Psychosis: The DFEND Randomized Clinical Trial.

JAMA network open

Gaughran F, Stringer D, Wojewodka G, Landau S, Smith S, Gardner-Sood P, Taylor D, Jordan H, Whiskey E, Krivoy A, Ciufolini S, Stubbs B, Casetta C, Williams J, Moore S, Allen L, Rathod S, Boardman A, Khalifa R, Firdosi M, McGuire P, Berk M, McGrath J.
PMID: 34962559
JAMA Netw Open. 2021 Dec 01;4(12):e2140858. doi: 10.1001/jamanetworkopen.2021.40858.

IMPORTANCE: People with psychotic disorders have an increased risk of vitamin D deficiency, which is evident during first-episode psychosis (FEP) and associated with unfavorable mental and physical health outcomes.OBJECTIVE: To examine whether vitamin D supplementation contributes to improved clinical...

Peak Width of Skeletonized Water Diffusion MRI in the Neonatal Brain.

Frontiers in neurology

Blesa M, Galdi P, Sullivan G, Wheater EN, Stoye DQ, Lamb GJ, Quigley AJ, Thrippleton MJ, Bastin ME, Boardman JP.
PMID: 32318015
Front Neurol. 2020 Apr 03;11:235. doi: 10.3389/fneur.2020.00235. eCollection 2020.

Preterm birth is closely associated with cognitive impairment and generalized dysconnectivity of neural networks inferred from water diffusion MRI (dMRI) metrics. Peak width of skeletonized mean diffusivity (PSMD) is a metric derived from histogram analysis of mean diffusivity across...

Understanding the Molecular-Level Interactions of Glucosamine-Glycerol Assemblies: A Model System for Chitosan Plasticization.

ACS omega

Smith DR, Escobar AP, Andris MN, Boardman BM, Peters GM.
PMID: 34632182
ACS Omega. 2021 Sep 23;6(39):25227-25234. doi: 10.1021/acsomega.1c03016. eCollection 2021 Oct 05.

Glycerol is the most widely used plasticizer for the biopolymer chitosan. However, there remains a lack of understanding of the molecular-level interactions between chitosan and glycerol. Here, we describe an in-depth spectroscopic study of the intermolecular interactions between the...

What Is Direct Allorecognition?.

Current transplantation reports

Boardman DA, Jacob J, Smyth LA, Lombardi G, Lechler RI.
PMID: 27909647
Curr Transplant Rep. 2016;3(4):275-283. doi: 10.1007/s40472-016-0115-8. Epub 2016 Oct 07.

Direct allorecognition is the process by which donor-derived major histocompatibility complex (MHC)-peptide complexes, typically presented by donor-derived 'passenger' dendritic cells, are recognised directly by recipient T cells. In this review, we discuss the two principle theories which have been...

Colorectal Cancer with Residual Polyp of Origin: A Model of Malignant Transformation.

Translational oncology

Druliner BR, Rashtak S, Ruan X, Bae T, Vasmatzis N, O'Brien D, Johnson R, Felmlee-Devine D, Washechek-Aletto J, Basu N, Liu H, Smyrk T, Abyzov A, Boardman LA.
PMID: 27567950
Transl Oncol. 2016 Aug;9(4):280-6. doi: 10.1016/j.tranon.2016.06.002. Epub 2016 Jul 09.

The majority of colorectal cancers (CRCs) arise from adenomatous polyps. In this study, we sought to present the underrecognized CRC with the residual polyp of origin (CRC RPO+) as an entity to be utilized as a model to study...

Showing 25 to 36 of 171 entries