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Showing 25 to 36 of 247 entries
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Determinants of CD19-positive vs CD19-negative relapse after tisagenlecleucel for B-cell acute lymphoblastic leukemia.

Leukemia

Dourthe ME, Rabian F, Yakouben K, Chevillon F, Cabannes-Hamy A, Méchinaud F, Grain A, Chaillou D, Rahal I, Caillat-Zucman S, Lesprit E, Naudin J, Roupret-Serzec J, Parquet N, Brignier A, Guérin-El Khourouj V, Lainey E, Caye-Eude A, Cavé H, Clappier E, Mathis S, Azoulay E, Dalle JH, Dhédin N, Madelaine I, Larghero J, Boissel N, Baruchel A.
PMID: 34002027
Leukemia. 2021 Dec;35(12):3383-3393. doi: 10.1038/s41375-021-01281-7. Epub 2021 May 17.

Tisagenlecleucel therapy has shown promising efficacy for relapsed/refractory (R/R) B-cell precursor acute lymphoblastic leukemia (BCP-ALL). However, relapses occur in 30-50% of patients. Determinants for CD19

Systematic assessment of the humoral response against SARS-CoV-2 in a French cohort of 283 patients with rheumatic diseases.

Joint bone spine

Gros C, Mariaggi AA, Meritet JF, André E, Boisson M, Combier A, Descamps E, Frantz C, Wanono S, Morel J, Avouac J, Rozenberg F, Miceli-Richard C, Fogel O.
PMID: 34883243
Joint Bone Spine. 2021 Dec 06;89(3):105312. doi: 10.1016/j.jbspin.2021.105312. Epub 2021 Dec 06.

OBJECTIVES: To estimate the seroprevalence of SARS-CoV-2 infection in patients with rheumatic diseases and to specify the proportion of asymptomatic and symptomatic forms of COVID-19.METHODS: We screened for SARS-CoV-2 infection among spondyloarthritis (SpA, n=143) or rheumatoid arthritis (RA, n=140)...

Ser.

Frontiers in cell and developmental biology

Wang F, Zhu C, Cai S, Boudreau A, Kim SJ, Bissell M, Shao J.
PMID: 34235154
Front Cell Dev Biol. 2021 Jun 21;9:692269. doi: 10.3389/fcell.2021.692269. eCollection 2021.

The essential actin-binding factor profilin-1 (Pfn1) is a non-classical tumor suppressor with the abilities toboth inhibit cellular proliferation and augment chemotherapy-induced apoptosis. Besides actin, Pfn1 interacts with proteins harboring the poly-L-proline (PLP) motifs. Our recent work demonstrated that both...

Comparison of image quality between spectral photon-counting CT and dual-layer CT for the evaluation of lung nodules: a phantom study.

European radiology

Si-Mohamed SA, Greffier J, Miailhes J, Boccalini S, Rodesch PA, Vuillod A, van der Werf N, Dabli D, Racine D, Rotzinger D, Becce F, Yagil Y, Coulon P, Vlassenbroek A, Boussel L, Beregi JP, Douek P.
PMID: 34185147
Eur Radiol. 2022 Jan;32(1):524-532. doi: 10.1007/s00330-021-08103-5. Epub 2021 Jun 29.

OBJECTIVES: To evaluate the image quality (IQ) of a spectral photon-counting CT (SPCCT) using filtered back projection (FBP) and hybrid iterative reconstruction (IR) algorithms (iDoseMETHODS: Two phantoms were scanned using a standard lung protocol (120 kVp, 40 mAs) with...

Reuse of medical face masks in domestic and community settings without sacrificing safety: Ecological and economical lessons from the Covid-19 pandemic.

Chemosphere

Alcaraz JP, Le Coq L, Pourchez J, Thomas D, Chazelet S, Boudry I, Barbado M, Silvent S, Dessale C, Antoine F, Guimier-Pingault C, Cortella L, Rouif S, Bardin-Monnier N, Charvet A, Dufaud O, Leclerc L, Montigaud Y, Laurent C, Verhoeven P, Joubert A, Bouhanguel A, Andres Y, Gaffé J, Martin DK, Huet C, Boisset S, Maurin M, Rumeau P, Charlot F, Richaud E, Moreau-Gaudry A, Bonneterre V, Cinquin P, Landelle C.
PMID: 34600007
Chemosphere. 2022 Feb;288:132364. doi: 10.1016/j.chemosphere.2021.132364. Epub 2021 Sep 29.

The need for personal protective equipment increased exponentially in response to the Covid-19 pandemic. To cope with the mask shortage during springtime 2020, a French consortium was created to find ways to reuse medical and respiratory masks in healthcare...

Symptom burden, quality of life, functioning and emotional distress in survivors of human papillomavirus associated oropharyngeal cancer: An Australian cohort.

Oral oncology

McDowell L, Casswell G, Bressel M, Drosdowsky A, Rischin D, Coleman A, Shrestha S, D'Costa I, Fua T, Tiong A, Liu C, Gough K.
PMID: 34653749
Oral Oncol. 2021 Nov;122:105560. doi: 10.1016/j.oraloncology.2021.105560. Epub 2021 Oct 13.

BACKGROUND: This cross-sectional study examines patient-reported outcomes and functioning-based subgroups in human papillomavirus-associated oropharyngeal cancer survivors treated with chemoradiotherapy ≥12 months prior.METHOD: Survivors completed EORTC QLQ-C30, MDASI-HN and PROMIS-Emotional distress questionnaires. Subgroups were identified via two-step clustering of QLQ-C30...

Brain response to food odors is not associated with body mass index and obesity-related metabolic health measures.

Appetite

Poessel M, Morys F, Breuer N, Villringer A, Hummel T, Horstmann A.
PMID: 34715246
Appetite. 2022 Jan 01;168:105774. doi: 10.1016/j.appet.2021.105774. Epub 2021 Oct 29.

Smell perception plays a role in eating behavior and might be involved in the development of obesity. In fact, olfactory function is impaired in obesity and might depend on metabolic health factors. To date, the underlying neural mechanisms remain...

Performance of Spectral Photon-Counting Coronary CT Angiography and Comparison with Energy-Integrating-Detector CT: Objective Assessment with Model Observer.

Diagnostics (Basel, Switzerland)

Rotzinger DC, Racine D, Becce F, Lahoud E, Erhard K, Si-Mohamed SA, Greffier J, Viry A, Boussel L, Meuli RA, Yagil Y, Monnin P, Douek PC.
PMID: 34943611
Diagnostics (Basel). 2021 Dec 16;11(12). doi: 10.3390/diagnostics11122376.

AIMS: To evaluate spectral photon-counting CT's (SPCCT) objective image quality characteristics in vitro, compared with standard-of-care energy-integrating-detector (EID) CT.METHODS: We scanned a thorax phantom with a coronary artery module at 10 mGy on a prototype SPCCT and a clinical...

Shedding light on those who provide support.

eLife

Loissel E.
PMID: 33226339
Elife. 2020 Nov 23;9. doi: 10.7554/eLife.64739.

An eLife survey explores the experiences of those in the research community who support colleagues struggling with their mental health.

Reduced Olfactory Bulb Volume in Obesity and Its Relation to Metabolic Health Status.

Frontiers in human neuroscience

Poessel M, Breuer N, Joshi A, Pampel A, Villringer A, Hummel T, Horstmann A.
PMID: 33328935
Front Hum Neurosci. 2020 Nov 27;14:586998. doi: 10.3389/fnhum.2020.586998. eCollection 2020.

Smell perception plays an important role in eating behavior and might be involved in body weight gain. Since a body of literature implies that olfactory perception and function is hampered in obesity, we here investigate neuroanatomical correlates of this...

A conventional-to-spectral CT image translation augmentation workflow for robust contrast injection-independent organ segmentation.

Medical physics

Lartaud PJ, Dupont C, Hallé D, Schleef A, Dessouky R, Vlachomitrou AS, Rouet JM, Nempont O, Boussel L.
PMID: 34689353
Med Phys. 2021 Oct 24; doi: 10.1002/mp.15310. Epub 2021 Oct 24.

PURPOSE: In computed tomography (CT) cardiovascular imaging, the numerous contrast injection protocols used to enhance structures make it difficult to gather training datasets for deep learning applications supporting diverse protocols. Moreover, creating annotations on noncontrast scans is extremely tedious....

Lack of Durable Remission with Conventional-Dose Total Skin Electron Therapy for the Management of Sezary Syndrome and Multiply Relapsed Mycosis Fungoides.

Cancers

Campbell BA, Ryan G, McCormack C, Tangas E, Bressel M, Twigger R, Buelens O, van der Weyden C, Prince HM.
PMID: 31717353
Cancers (Basel). 2019 Nov 08;11(11). doi: 10.3390/cancers11111758.

Mycosis fungoides (MF) and Sezary syndrome (SS) are multi-relapsing, morbid, cutaneous T-cell lymphomas. Optimal treatment sequencing remains undefined. Total skin electron therapy (TSE) is a highly technical, skin-directed treatment, uniquely producing symptom-free and treatment-free intervals. Recent publications favour low-dose...

Showing 25 to 36 of 247 entries