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Showing 25 to 36 of 234 entries
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Doppler ultrasound predicts successful discontinuation of biological DMARDs in rheumatoid arthritis patients in clinical remission.

Rheumatology (Oxford, England)

Terslev L, Brahe CH, Hetland ML, Georgiadis S, Ellegaard K, Juul L, Huynh T, Døhn UM, Fana V, Møller T, Krabbe S, Ørnbjerg LM, Glinatsi D, Røgind H, Hansen A, Nørregaard J, Jacobsen S, Jensen DV, Manilo N, Asmussen K, Boesen M, Rastiemadabadi Z, Morsel-Carlsen L, Møller JM, Krogh NS, Østergaard M.
PMID: 33748831
Rheumatology (Oxford). 2021 Dec 01;60(12):5549-5559. doi: 10.1093/rheumatology/keab276.

OBJECTIVE: To assess the ability of ultrasound to predict successful tapering and successful discontinuation of biological DMARDs (bDMARDs) at the 2-year follow-up in RA patients in sustained remission.METHODS: Patients in sustained remission (DAS28-CRP ≤ 2.6) and with no radiographic...

Conservative treatment of perforated diverticulitis: following the latest guidelines pays dividends.

Lancet (London, England)

Toresen A, Johanssen A, Ansari OBA, Holmedal SH, Schultz JK.
PMID: 34688370
Lancet. 2021 Oct 23;398(10310):1517. doi: 10.1016/S0140-6736(21)02003-1.

No abstract available.

The US Food and Drug Administration's authorisation of Purdue's controlled-release methylphenidate for adult ADHD: comments on the regulatory practice.

Journal of the Royal Society of Medicine

Boesen K, Juhl Jørgensen K, Gøtzsche PC.
PMID: 33759627
J R Soc Med. 2021 Aug;114(8):377-380. doi: 10.1177/0141076821994535. Epub 2021 Mar 24.

No abstract available.

Thyroid Hormone Transporter Deficiency in Mice Impacts Multiple Stages of GABAergic Interneuron Development.

Cerebral cortex (New York, N.Y. : 1991)

Mayerl S, Chen J, Salveridou E, Boelen A, Darras VM, Heuer H.
PMID: 34339499
Cereb Cortex. 2022 Jan 10;32(2):329-341. doi: 10.1093/cercor/bhab211.

Cortical interneuron neurogenesis is strictly regulated and depends on the presence of thyroid hormone (TH). In particular, inhibitory interneurons expressing the calcium binding protein Parvalbumin are highly sensitive toward developmental hypothyroidism. Reduced numbers of Parvalbumin-positive interneurons are observed in...

Correction to: Cross-sectional study of medical advertisements in a national general medical journal: evidence, cost, and safe use of advertised versus comparative drugs.

Research integrity and peer review

Boesen K, Simonsen AL, Jørgensen KJ, Gøtzsche PC.
PMID: 34116717
Res Integr Peer Rev. 2021 Jun 11;6(1):10. doi: 10.1186/s41073-021-00114-6.

No abstract available.

Management of oral biofilms by nisin delivery in adhesive microdevices.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Birk SE, Mosgaard MD, Kjeldsen RB, Boisen A, Meyer RL, Nielsen LH.
PMID: 34302949
Eur J Pharm Biopharm. 2021 Oct;167:83-88. doi: 10.1016/j.ejpb.2021.07.007. Epub 2021 Jul 22.

Numerous beneficial microbes thrive in the oral cavity where they form biofilms on dental and mucosal surfaces to get access to nutrients, and to avoid being carried away with the saliva. However, biofilm formation is also a virulence factor...

High-resolution structure of native toxin A from Clostridioides difficile.

EMBO reports

Aminzadeh A, Larsen CE, Boesen T, Jørgensen R.
PMID: 34817920
EMBO Rep. 2021 Nov 24;e53597. doi: 10.15252/embr.202153597. Epub 2021 Nov 24.

Clostridioides difficile infections have emerged as the leading cause of healthcare-associated infectious diarrhea. Disease symptoms are mainly caused by the virulence factors, TcdA and TcdB, which are large homologous multidomain proteins. Here, we report a 2.8 Å resolution cryo-EM...

Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers.

Nature communications

Coignard J, Lush M, Beesley J, O'Mara TA, Dennis J, Tyrer JP, Barnes DR, McGuffog L, Leslie G, Bolla MK, Adank MA, Agata S, Ahearn T, Aittomäki K, Andrulis IL, Anton-Culver H, Arndt V, Arnold N, Aronson KJ, Arun BK, Augustinsson A, Azzollini J, Barrowdale D, Baynes C, Becher H, Bermisheva M, Bernstein L, Białkowska K, Blomqvist C, Bojesen SE, Bonanni B, Borg A, Brauch H, Brenner H, Burwinkel B, Buys SS, Caldés T, Caligo MA, Campa D, Carter BD, Castelao JE, Chang-Claude J, Chanock SJ, Chung WK, Claes KBM, Clarke CL, Collée JM, Conroy DM, Czene K, Daly MB, Devilee P, Diez O, Ding YC, Domchek SM, Dörk T, Dos-Santos-Silva I, Dunning AM, Dwek M, Eccles DM, Eliassen AH, Engel C, Eriksson M, Evans DG, Fasching PA, Flyger H, Fostira F, Friedman E, Fritschi L, Frost D, Gago-Dominguez M, Gapstur SM, Garber J, Garcia-Barberan V, García-Closas M, García-Sáenz JA, Gaudet MM, Gayther SA, Gehrig A, Georgoulias V, Giles GG, Godwin AK, Goldberg MS, Goldgar DE, González-Neira A, Greene MH, Guénel P, Haeberle L, Hahnen E, Haiman CA, Håkansson N, Hall P, Hamann U, Harrington PA, Hart SN, He W, Hogervorst FBL, Hollestelle A, Hopper JL, Horcasitas DJ, Hulick PJ, Hunter DJ, Imyanitov EN, Jager A, Jakubowska A, James PA, Jensen UB, John EM, Jones ME, Kaaks R, Kapoor PM, Karlan BY, Keeman R, Khusnutdinova E, Kiiski JI, Ko YD, Kosma VM, Kraft P, Kurian AW, Laitman Y, Lambrechts D, Le Marchand L, Lester J, Lesueur F, Lindstrom T, Lopez-Fernández A, Loud JT, Luccarini C, Mannermaa A, Manoukian S, Margolin S, Martens JWM, Mebirouk N, Meindl A, Miller A, Milne RL, Montagna M, Nathanson KL, Neuhausen SL, Nevanlinna H, Nielsen FC, O'Brien KM, Olopade OI, Olson JE, Olsson H, Osorio A, Ottini L, Park-Simon TW, Parsons MT, Pedersen IS, Peshkin B, Peterlongo P, Peto J, Pharoah PDP, Phillips KA, Polley EC, Poppe B, Presneau N, Pujana MA, Punie K, Radice P, Rantala J, Rashid MU, Rennert G, Rennert HS, Robson M, Romero A, Rossing M, Saloustros E, Sandler DP, Santella R, Scheuner MT, Schmidt MK, Schmidt G, Scott C, Sharma P, Soucy P, Southey MC, Spinelli JJ, Steinsnyder Z, Stone J, Stoppa-Lyonnet D, Swerdlow A, Tamimi RM, Tapper WJ, Taylor JA, Terry MB, Teulé A, Thull DL, Tischkowitz M, Toland AE, Torres D, Trainer AH, Truong T, Tung N, Vachon CM, Vega A, Vijai J, Wang Q, Wappenschmidt B, Weinberg CR, Weitzel JN, Wendt C, Wolk A, Yadav S, Yang XR, Yannoukakos D, Zheng W, Ziogas A, Zorn KK, Park SK, Thomassen M, Offit K, Schmutzler RK, Couch FJ, Simard J, Chenevix-Trench G, Easton DF, Andrieu N, Antoniou AC.
PMID: 33990587
Nat Commun. 2021 May 14;12(1):2986. doi: 10.1038/s41467-021-23162-4.

A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-23162-4.

International Multi-Site Initiative to Develop an MRI-Inclusive Nomogram for Side-Specific Prediction of Extraprostatic Extension of Prostate Cancer.

Cancers

Wibmer AG, Kattan MW, Alessandrino F, Baur ADJ, Boesen L, Franco FB, Bonekamp D, Campa R, Cash H, Catalá V, Crouzet S, Dinnoo S, Eastham J, Fennessy FM, Ghabili K, Hohenfellner M, Levi AW, Ji X, Løgager V, Margolis DJ, Moldovan PC, Panebianco V, Penzkofer T, Puech P, Radtke JP, Rouvière O, Schlemmer HP, Sprenkle PC, Tempany CM, Vilanova JC, Weinreb J, Hricak H, Shukla-Dave A.
PMID: 34071842
Cancers (Basel). 2021 May 27;13(11). doi: 10.3390/cancers13112627.

BACKGROUND: To develop an international, multi-site nomogram for side-specific prediction of extraprostatic extension (EPE) of prostate cancer based on clinical, biopsy, and magnetic resonance imaging- (MRI) derived data.METHODS: Ten institutions from the USA and Europe contributed clinical and side-specific...

Association of fatal myocardial infarction with past level of physical activity: a pooled analysis of cohort studies.

European journal of preventive cardiology

Hansen KW, Peytz N, Blokstra A, Bojesen SE, Celis-Morales C, Chrysohoou C, Clays E, De Bacquer D, Galatius S, Gray SR, Ho F, Kavousi M, Koolhaas CM, Kouvari M, Løchen ML, Marques-Vidal P, Osler M, Panagiotakos D, Pell JP, Sulo G, Tell GS, Vassiliou V, Verschuren WMM, Prescott E.
PMID: 33564885
Eur J Prev Cardiol. 2021 Dec 20;28(14):1590-1598. doi: 10.1093/eurjpc/zwaa146.

AIMS: To assess the association between past level of physical activity (PA) and risk for death during the acute phase of myocardial infarction (MI) in a pooled analysis of cohort studies.METHODS AND RESULTS: European cohorts including participants with a...

Childhood ADHD and treatment outcome: the role of maternal functioning.

Child and adolescent psychiatry and mental health

Rasmussen PD, Storebø OJ, Shmueli-Goetz Y, Bojesen AB, Simonsen E, Bilenberg N.
PMID: 29983736
Child Adolesc Psychiatry Ment Health. 2018 Jun 14;12:31. doi: 10.1186/s13034-018-0234-3. eCollection 2018.

BACKGROUND: Relatively little is known about the role of maternal functioning in terms of attention deficit hyperactivity disorder (ADHD) symptoms, attachment style and resilience as predictive factors for treatment outcome when offspring are diagnosed with ADHD.OBJECTIVE: To investigate whether...

Pyrolytic carbon resonators for micromechanical thermal analysis.

Microsystems & nanoengineering

Nguyen LQ, Larsen PE, Larsen T, Goswami SB, Villanueva LG, Boisen A, Keller SS.
PMID: 31646000
Microsyst Nanoeng. 2019 Oct 21;5:58. doi: 10.1038/s41378-019-0094-x. eCollection 2019.

Thermal analysis is essential for the characterization of polymers and drugs. However, the currently established methods require a large amount of sample. Here, we present pyrolytic carbon resonators as promising tools for micromechanical thermal analysis (MTA) of nanograms of...

Showing 25 to 36 of 234 entries