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Showing 25 to 36 of 228 entries
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Site-specific detection of protein secondary structure using 2D IR dihedral indexing: a proposed assembly mechanism of oligomeric hIAPP.

Chemical science

Maj M, Lomont JP, Rich KL, Alperstein AM, Zanni MT.
PMID: 29619202
Chem Sci. 2017 Nov 03;9(2):463-474. doi: 10.1039/c7sc03789a. eCollection 2018 Jan 14.

Human islet amyloid polypeptide (hIAPP) aggregates into fibrils through oligomers that have been postulated to contain α-helices as well as β-sheets. We employ a site-specific isotope labeling strategy that is capable of detecting changes in dihedral angles when used...

Visible light amination/Smiles cascade: access to phthalazine derivatives.

Chemical science

Brachet E, Marzo L, Selkti M, König B, Belmont P.
PMID: 30155150
Chem Sci. 2016 Aug 01;7(8):5002-5006. doi: 10.1039/c6sc01095d. Epub 2016 May 06.

We report the synthesis of various phthalazines

Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota.

Scientific reports

Harach T, Marungruang N, Duthilleul N, Cheatham V, Mc Coy KD, Frisoni G, Neher JJ, Fåk F, Jucker M, Lasser T, Bolmont T.
PMID: 28176819
Sci Rep. 2017 Feb 08;7:41802. doi: 10.1038/srep41802.

Alzheimer's disease is the most common form of dementia in the western world, however there is no cure available for this devastating neurodegenerative disorder. Despite clinical and experimental evidence implicating the intestinal microbiota in a number of brain disorders,...

An Original L-shape, Tunable N-Heterocyclic Carbene Platform for Efficient Gold(I) Catalysis.

Angewandte Chemie (International ed. in English)

Tang Y, Benaissa I, Huynh M, Vendier L, Lugan N, Bastin S, Belmont P, César V, Michelet V.
PMID: 30957361
Angew Chem Int Ed Engl. 2019 Jun 11;58(24):7977-7981. doi: 10.1002/anie.201901090. Epub 2019 May 08.

The synthesis and characterization of original NHC ligands based on an imidazo[1,5-a]pyridin-3-ylidene (IPy) scaffold functionalized with a flanking barbituric heterocycle is described as well as their use as tunable ligands for efficient gold-catalyzed C-N, C-O, and C-C bond formations....

Advances in edge diffraction algorithms.

Journal of the Optical Society of America. A, Optics, image science, and vision

Harness A, Shaklan S, Cash W, Dumont P.
PMID: 29400876
J Opt Soc Am A Opt Image Sci Vis. 2018 Feb 01;35(2):275-285. doi: 10.1364/JOSAA.35.000275.

Starshade external occulters are a leading technology that provide the starlight suppression needed to directly image and spectroscopically characterize Earth-sized exoplanets in the habitable zone of nearby stars. A high-priority technology area identified in need of development for a...

Local order and cluster formation in model fluids with competing interactions: a simulation and theoretical study.

Physical chemistry chemical physics : PCCP

Bomont JM, Costa D, Bretonnet JL.
PMID: 32096535
Phys Chem Chem Phys. 2020 Mar 04;22(9):5355-5365. doi: 10.1039/c9cp06710h.

In a preliminary study [Phys. Chem. Chem. Phys., 2017, 19, 15247], we have recently documented an elusive mechanism underlying the cluster formation in model fluids with microscopic competing interactions (hard-sphere two-Yukawa). This mechanism consists in a tiny rearrangement of...

Nightside condensation of iron in an ultrahot giant exoplanet.

Nature

Ehrenreich D, Lovis C, Allart R, Zapatero Osorio MR, Pepe F, Cristiani S, Rebolo R, Santos NC, Borsa F, Demangeon O, Dumusque X, González Hernández JI, Casasayas-Barris N, Ségransan D, Sousa S, Abreu M, Adibekyan V, Affolter M, Allende Prieto C, Alibert Y, Aliverti M, Alves D, Amate M, Avila G, Baldini V, Bandy T, Benz W, Bianco A, Bolmont É, Bouchy F, Bourrier V, Broeg C, Cabral A, Calderone G, Pallé E, Cegla HM, Cirami R, Coelho JMP, Conconi P, Coretti I, Cumani C, Cupani G, Dekker H, Delabre B, Deiries S, D'Odorico V, Di Marcantonio P, Figueira P, Fragoso A, Genolet L, Genoni M, Génova Santos R, Hara N, Hughes I, Iwert O, Kerber F, Knudstrup J, Landoni M, Lavie B, Lizon JL, Lendl M, Lo Curto G, Maire C, Manescau A, Martins CJAP, Mégevand D, Mehner A, Micela G, Modigliani A, Molaro P, Monteiro M, Monteiro M, Moschetti M, Müller E, Nunes N, Oggioni L, Oliveira A, Pariani G, Pasquini L, Poretti E, Rasilla JL, Redaelli E, Riva M, Santana Tschudi S, Santin P, Santos P, Segovia Milla A, Seidel JV, Sosnowska D, Sozzetti A, Spanò P, Suárez Mascareño A, Tabernero H, Tenegi F, Udry S, Zanutta A, Zerbi F.
PMID: 32161364
Nature. 2020 Apr;580(7805):597-601. doi: 10.1038/s41586-020-2107-1. Epub 2020 Mar 11.

Ultrahot giant exoplanets receive thousands of times Earth's insolation

A semianalytical "reverse" approach to link structure and microscopic interactions in two-Yukawa competing fluids.

The Journal of chemical physics

Bretonnet JL, Bomont JM, Costa D.
PMID: 30579317
J Chem Phys. 2018 Dec 21;149(23):234907. doi: 10.1063/1.5047448.

We study theoretically a prototype hard-sphere two-Yukawa model with competing interactions, under thermodynamic conditions associated with the formation of clusters. We adopt the analytically solvable random phase approximation and show that this theory predicts reasonably well the structure of...

Formation of CrSi and CrSi2 upon annealing of Cr overlayers on Si(111).

Physical review. B, Condensed matter

Bolmont D, Gewinner G, Peruchetti JC, Pirri C, Wetzel P.
PMID: 9940806
Phys Rev B Condens Matter. 1987 Apr 15;35(11):5880-5883. doi: 10.1103/physrevb.35.5880.

No abstract available.

Probing the Co coordination at the Si/CoSi2(111) interface by photoemission.

Physical review. B, Condensed matter

Bolmont D, Gewinner G, Haderbache L, Peruchetti JC, Pirri C, Wetzel P.
PMID: 9948140
Phys Rev B Condens Matter. 1989 Jun 15;39(17):12704-12707. doi: 10.1103/physrevb.39.12704.

No abstract available.

Surface states and reconstruction of epitaxial sqrt 3 x sqrt 3 R30 degrees Er silicide on Si(111).

Physical review. B, Condensed matter

Bolmont D, Gewinner G, Pirri C, Saintenoy S, Wetzel P.
PMID: 9975191
Phys Rev B Condens Matter. 1994 Oct 15;50(15):10886-10892. doi: 10.1103/physrevb.50.10886.

No abstract available.

From Immune Dysregulations to Therapeutic Perspectives in Myelodysplastic Syndromes: A Review.

Diagnostics (Basel, Switzerland)

Comont T, Treiner E, Vergez F.
PMID: 34829329
Diagnostics (Basel). 2021 Oct 26;11(11). doi: 10.3390/diagnostics11111982.

The pathophysiology of myelodysplastic syndromes (MDSs) is complex and often includes immune dysregulation of both the innate and adaptive immune systems. Whereas clonal selection mainly involves smoldering inflammation, a cellular immunity dysfunction leads to increased apoptosis and blast proliferation....

Showing 25 to 36 of 228 entries