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Showing 13 to 24 of 331 entries
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[Systemic mastocytosis in childhood: report of 3 cases].

Jornal de pediatria

Fernandes EI, de Faria BC, Cartell A, dos Santos BA, Cestari TF.
PMID: 14647801
J Pediatr (Rio J). 2002 Mar-Apr;78(2):176-80.

OBJECTIVE: Mastocytosis comprises a group of diseases characterized by accumulation of mast cells on the skin, with the possibility of affecting other systems. Symptoms can be exclusively cutaneous, associated with symptoms of the organs involved or even systemic, due...

Observational study on factors related to health-promoting community activity development in primary care (frAC Project): a study protocol.

BMJ open

March S, Ripoll J, Ruiz-Giménez JL, Montaner Gomis I, Benedé Azagra CB, Elizalde Soto L, Vidal MC, Bauzà Amengual Mde L, Planas Juan T, Maria Pérez Mariano D, Llull Sarralde M, Bajo Viñas R, Jordan Martin M, Solano Villarubia C, Rodriguez Bajo M, Cordoba Victoria M, Badia Capdevila M, Serrano Ferrandez E, Bosom Diumenjo M, Zabaleta Del Olmo N, Bolívar-Ribas B, Antoñanzas Lombarte A, Bregel Cotaina S, Calvo Tocado A, Olivan Blázquez B, Magallón Botaya R, Marín Palacios P, Echauri Ozcoidi M, Perez-Jarauta MJ, Ramos M.
PMID: 22586288
BMJ Open. 2012 May 14;2(3). doi: 10.1136/bmjopen-2012-001287. Print 2012.

INTRODUCTION: According to Spanish health regulations, primary care professionals have the responsibility to carry out health-promoting community activities (CAs). However, in practice, their implementation is not as widespread as it should be. The aims of this study were to...

Orexin-1 receptor blockade dysregulates REM sleep in the presence of orexin-2 receptor antagonism.

Frontiers in neuroscience

Dugovic C, Shelton JE, Yun S, Bonaventure P, Shireman BT, Lovenberg TW.
PMID: 24592208
Front Neurosci. 2014 Feb 14;8:28. doi: 10.3389/fnins.2014.00028. eCollection 2014.

In accordance with the prominent role of orexins in the maintenance of wakefulness via activation of orexin-1 (OX1R) and orexin-2 (OX2R) receptors, various dual OX1/2R antagonists have been shown to promote sleep in animals and humans. While selective blockade...

(R)-(-)-Quinuclidin-3-ol.

Acta crystallographica. Section E, Structure reports online

Rousselin Y, Clavel A, Bonnaventure I.
PMID: 24454106
Acta Crystallogr Sect E Struct Rep Online. 2013 Oct 19;69:o1672. doi: 10.1107/S1600536813026998. eCollection 2013 Oct 19.

The structure of the title compound [alternatively called (R)-(-)-1-aza-bicyclo-[2.2.2]octan-3-ol], C7H13NO, at 100 K has hexa-gonal (P61) symmetry. The structure shows a twist along the C-N pseudo-threefold axis. In the crystal, mol-ecules are linked via O-H⋯N hydrogen bonds, forming infinite...

An air carrier flow system for the spectrophotometric determination of water in biodiesel exploiting bleaching of the cobalt chloride complex.

Talanta

Pereira AC, Reis BF, Rocha FR.
PMID: 25281068
Talanta. 2015 Jan;131:21-5. doi: 10.1016/j.talanta.2014.07.049. Epub 2014 Jul 27.

Water content is an important parameter in biodiesel quality control, as excess of this substance may lead to biofuel hydrolysis, microorganism proliferation, and alterations in the oxidative stability of the biofuel. The threshold limit is established as 200 mg...

(2E,4R,5R,6S)-2-(4,5,6-Trihy-droxy-cyclo-hex-2-en-1-yl-idene)acetonitrile.

Acta crystallographica. Section E, Structure reports online

Guedem AN, Sandjo LP, Opatz T, Schollmeyer D, Ngadjui BT.
PMID: 22969620
Acta Crystallogr Sect E Struct Rep Online. 2012 Sep 01;68:o2737. doi: 10.1107/S1600536812035313. Epub 2012 Aug 23.

The crystal structure of the title compound, C(8)H(9)NO(3), is characterized by a complex three-dimensional hydrogen-bond network in which every mol-ecule is connected to six symmetry-related neighbours.

Author Correction: The interferon-inducible isoform of NCOA7 inhibits endosome-mediated viral entry.

Nature microbiology

Doyle T, Moncorgé O, Bonaventure B, Pollpeter D, Lussignol M, Tauziet M, Apolonia L, Catanese MT, Goujon C, Malim MH.
PMID: 30670794
Nat Microbiol. 2019 Mar;4(3):539. doi: 10.1038/s41564-019-0366-0.

In the version of Supplementary Fig. 5a originally published with this Letter, the authors mistakenly duplicated images of LAMP1 staining in place of CD63 staining; this has now been amended to the correct version shown below.

Sepsis by .

Case reports in infectious diseases

Caserza L, Piatti G, Bonaventura A, Liberale L, Carbone F, Dallegri F, Ottonello L, Gustinetti G, Del Bono V, Montecucco F.
PMID: 29318064
Case Rep Infect Dis. 2017;2017:2527980. doi: 10.1155/2017/2527980. Epub 2017 Nov 26.

No abstract available.

Behavioural thermoregulation via microhabitat selection of winter sleeping areas in an endangered primate: implications for habitat conservation.

Royal Society open science

Campbell LAD, Tkaczynski PJ, Mouna M, Derrou A, Oukannou L, Majolo B, van Lavieren E.
PMID: 30662730
R Soc Open Sci. 2018 Dec 05;5(12):181113. doi: 10.1098/rsos.181113. eCollection 2018 Dec.

Strategic microhabitat selection allows animals in seasonally cold environments to reduce homeostatic energy costs, particularly overnight when thermoregulatory demands are greatest. Suitable sleeping areas may therefore represent important resources for winter survival. Knowledge of microhabitat use and potential impacts...

Re-evaluation of Adrenocorticotropic Hormone and Melanocyte Stimulating Hormone Activation of GPR139 .

Frontiers in pharmacology

Nepomuceno D, Kuei C, Dvorak C, Lovenberg T, Liu C, Bonaventure P.
PMID: 29599718
Front Pharmacol. 2018 Mar 02;9:157. doi: 10.3389/fphar.2018.00157. eCollection 2018.

It is now well established that GPR139, a G-protein coupled receptor exclusively expressed in the brain and pituitary, is activated by the essential amino acids L-tryptophan (L-Trp) and L-phenylalanine (L-Phe) via G

Effects of diazoxide in multiple sclerosis: A randomized, double-blind phase 2 clinical trial.

Neurology(R) neuroimmunology & neuroinflammation

Villoslada P, Rovira A, Montalban X, Arroyo R, Paul F, Meca-Lallana V, Ramo C, Fernandez O, Saiz A, Garcia-Merino A, Ramió-Torrentà L, Casanova B, Oreja-Guevara C, Muñoz D, Martinez-Rodriguez JE, Lensch E, Prieto JM, Meuth SG, Nuñez X, Campás C, Pugliese M.
PMID: 26405686
Neurol Neuroimmunol Neuroinflamm. 2015 Sep 10;2(5):e147. doi: 10.1212/NXI.0000000000000147. eCollection 2015 Oct.

OBJECTIVE: The aim of this study was to test the safety of diazoxide and to search for signs of efficacy in patients with relapsing-remitting multiple sclerosis (RRMS).METHODS: In this multicenter, randomized, placebo-controlled, double-blind trial (treatment allocation was concealed), 102...

GPR139 and Dopamine D2 Receptor Co-express in the Same Cells of the Brain and May Functionally Interact.

Frontiers in neuroscience

Wang L, Lee G, Kuei C, Yao X, Harrington A, Bonaventure P, Lovenberg TW, Liu C.
PMID: 30971885
Front Neurosci. 2019 Mar 26;13:281. doi: 10.3389/fnins.2019.00281. eCollection 2019.

GPR139, a G

Showing 13 to 24 of 331 entries