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Showing 25 to 36 of 1051 entries
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Patients with chronic lymphocytic leukemia and complex karyotype show an adverse outcome even in absence of .

Oncotarget

Puiggros A, Collado R, Calasanz MJ, Ortega M, Ruiz-Xivillé N, Rivas-Delgado A, Luño E, González T, Navarro B, García-Malo M, Valiente A, Hernández JÁ, Ardanaz MT, Piñan MÁ, Blanco ML, Hernández-Sánchez M, Batlle-López A, Salgado R, Salido M, Ferrer A, Abrisqueta P, Gimeno E, Abella E, Ferrá C, Terol MJ, Ortuño F, Costa D, Moreno C, Carbonell F, Bosch F, Delgado J, Espinet B.
PMID: 28903342
Oncotarget. 2017 Apr 21;8(33):54297-54303. doi: 10.18632/oncotarget.17350. eCollection 2017 Aug 15.

Genomic complexity identified by chromosome banding analysis (CBA) predicts a worse clinical outcome in CLL patients treated either with standard or new treatments. Herein, we analyzed the clinical impact of complex karyotypes (CK) with or without high-risk FISH deletions...

Rationale-based therapeutic combinations with PI3K inhibitors in cancer treatment.

Molecular & cellular oncology

Castel P, Toska E, Zumsteg ZS, Carmona FJ, Elkabets M, Bosch A, Scaltriti M.
PMID: 27308344
Mol Cell Oncol. 2014 Oct 29;1(3):e963447. doi: 10.4161/23723548.2014.963447. eCollection 2014.

The PI3K/AKT/mTOR signaling is important for cell proliferation, survival, and metabolism. Hyperactivation of this pathway is one of the most common signaling abnormalities observed in cancer and a substantial effort has recently been made to develop molecules targeting this...

Fourteen polymorphic microsatellite markers for the threatened Arnica montana (Asteraceae).

Applications in plant sciences

Duwe VK, Ismail SA, Buser A, Sossai E, Borsch T, Muller LA.
PMID: 25606354
Appl Plant Sci. 2015 Jan 05;3(1). doi: 10.3732/apps.1400091. eCollection 2015 Jan.

PREMISE OF THE STUDY: Microsatellite markers were developed to investigate population genetic structure in the threatened species Arnica montana. •METHODS AND RESULTS: Fourteen microsatellite markers with di-, tetra-, and hexanucleotide repeat motifs were developed for A. montana using 454...

Worldwide variations in artificial skyglow.

Scientific reports

Kyba CC, Tong KP, Bennie J, Birriel I, Birriel JJ, Cool A, Danielsen A, Davies TW, Outer PN, Edwards W, Ehlert R, Falchi F, Fischer J, Giacomelli A, Giubbilini F, Haaima M, Hesse C, Heygster G, Hölker F, Inger R, Jensen LJ, Kuechly HU, Kuehn J, Langill P, Lolkema DE, Nagy M, Nievas M, Ochi N, Popow E, Posch T, Puschnig J, Ruhtz T, Schmidt W, Schwarz R, Schwope A, Spoelstra H, Tekatch A, Trueblood M, Walker CE, Weber M, Welch DL, Zamorano J, Gaston KJ.
PMID: 25673335
Sci Rep. 2015 Feb 12;5:8409. doi: 10.1038/srep08409.

Despite constituting a widespread and significant environmental change, understanding of artificial nighttime skyglow is extremely limited. Until now, published monitoring studies have been local or regional in scope, and typically of short duration. In this first major international compilation...

FIB/SEM technology and high-throughput 3D reconstruction of dendritic spines and synapses in GFP-labeled adult-generated neurons.

Frontiers in neuroanatomy

Bosch C, Martínez A, Masachs N, Teixeira CM, Fernaud I, Ulloa F, Pérez-Martínez E, Lois C, Comella JX, DeFelipe J, Merchán-Pérez A, Soriano E.
PMID: 26052271
Front Neuroanat. 2015 May 21;9:60. doi: 10.3389/fnana.2015.00060. eCollection 2015.

The fine analysis of synaptic contacts is usually performed using transmission electron microscopy (TEM) and its combination with neuronal labeling techniques. However, the complex 3D architecture of neuronal samples calls for their reconstruction from serial sections. Here we show...

Fluorescence Detection from Single Dendrimers with Multiple Chromophores.

Angewandte Chemie (International ed. in English)

Gensch T, Hofkens J, Heirmann A, Tsuda K, Verheijen W, Vosch T, Christ T, Basché T, Müllen K, De Schryver FC.
PMID: 10649347
Angew Chem Int Ed Engl. 1999 Dec 16;38(24):3752-3756. doi: 10.1002/(sici)1521-3773(19991216)38:24<3752::aid-anie3752>3.0.co;2-y.

The differences in the fluorescence behavior of a polyphenylene dendrimer with eight peryleneimides chromophores (1) and a single hexaphenylperyleneimide chromophore have been investigated at a single-molecule level through the combination of ultrasensitive fluorescence detection and microscopy.

Dissociation of 70 S E. coli ribosomes induced by a ribosomal factor (DF). Electrophoretic studies of the ribosomal particles.

FEBS letters

J Talens, Kalousek F, Bosch L.
PMID: 11945527
FEBS Lett. 1970 Dec 23;12(1):4-8. doi: 10.1016/0014-5793(70)80580-4.

The dissociation of purified 70 S.E. coli ribosomes, induced by the dissociation factor DF, has been studied by submitting the reaction mixtures to electrophoresis on polyacrylamide gels. The electrophoretic analysis of the ribosome mixtures revealed a heterogeneity which escaped...

Generation and intermolecular reactions of 2-indolylacyl radicals.

Organic letters

Bennasar ML, Roca T, Griera R, Bosch J.
PMID: 11405689
Org Lett. 2001 May 31;3(11):1697-700. doi: 10.1021/ol0100576.

The generation of 2-indolylacyl radicals from the corresponding phenyl selenoesters, aldehydes, and alpha-keto carboxylic acids and the scope of their participation in intermolecular addition reactions to carbon-carbon double bonds have been studied. Whereas the phenyl selenoester method has provided...

Dark-bright solitons in inhomogeneous Bose-Einstein condensates.

Physical review letters

Busch T, Anglin JR.
PMID: 11461449
Phys Rev Lett. 2001 Jul 02;87(1):010401. doi: 10.1103/PhysRevLett.87.010401. Epub 2001 Jun 15.

We investigate dark-bright vector solitary wave solutions to the coupled nonlinear Schrödinger equations which describe an inhomogeneous two-species Bose-Einstein condensate. While these structures are well known in nonlinear fiber optics, we show that spatial inhomogeneity strongly affects their motion,...

Electrophilic Oxidative Additions upon 1,4-Dihydropyridines.

The Journal of organic chemistry

Lavilla R, Coll O, Kumar R, Bosch J.
PMID: 11672145
J Org Chem. 1998 Apr 17;63(8):2728-2730. doi: 10.1021/jo971947v.

No abstract available.

One- and two-dimensional silver-coordination networks containing pi-sandwiched silver-silver interactions.

Inorganic chemistry

Bosch E, Barnes CL.
PMID: 11978124
Inorg Chem. 2002 May 06;41(9):2543-7. doi: 10.1021/ic010795q.

The self-assembly of coordination networks from reaction of 2,4,6-trimesityl-1,3,5-triazine and silver(I) trifluoroacetate is described. A one-dimensional linear polymer is formed from solutions deficient in silver while a two-dimensional, graphite-like sheet is formed from solutions containing 3 equiv of silver...

Palladium(0)-Catalyzed Heteroarylation of 2- and 3-Indolylzinc Derivatives. An Efficient General Method for the Preparation of (2-Pyridyl)indoles and Their Application to Indole Alkaloid Synthesis.

The Journal of organic chemistry

Amat M, Hadida S, Pshenichnyi G, Bosch J.
PMID: 11671699
J Org Chem. 1997 May 16;62(10):3158-3175. doi: 10.1021/jo962169u.

Palladium(0)-catalyzed coupling of (1-(benzenesulfonyl)-2-indolyl)zinc chloride (1) and (1-(tert-butyldimethylsilyl)-3-indolyl)zinc chloride (6) with diversely substituted (alkyl, methoxy, methoxycarbonyl, nitro, hydroxy) 2-halopyridines gives the corresponding 2- and 3-(2-pyridyl)indoles [4 and 7 (or 8), respectively] in excellent yields. A series of other 3-(heteroaryl)indoles...

Showing 25 to 36 of 1051 entries