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Differentially methylated genes in proliferative verrucous leukoplakia reveal potential malignant biomarkers for oral squamous cell carcinoma.

Oral oncology

Herreros-Pomares A, Llorens C, Soriano B, Bagan L, Moreno A, Calabuig-Fariñas S, Jantus-Lewintre E, Bagan J.
PMID: 33657465
Oral Oncol. 2021 May;116:105191. doi: 10.1016/j.oraloncology.2021.105191. Epub 2021 Feb 28.

OBJECTIVES: To explore the pathophysiology of proliferative verrucous leucoplakia (PVL) through a methylated DNA immunoprecipitation and high-throughput sequencing (MeDIP-seq) case-control study.MATERIALS AND METHODS: Oral biopsies from ten PVL patients and five healthy individuals were obtained and used to compare...

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Herreros-Pomares A, Llorens C, Soriano B, et al. Differentially methylated genes in proliferative verrucous leukoplakia reveal potential malignant biomarkers for oral squamous cell carcinoma. Oral Oncol. 2021;116:105191doi: 10.1016/j.oraloncology.2021.105191.
Herreros-Pomares, A., Llorens, C., Soriano, B., Bagan, L., Moreno, A., Calabuig-Fariñas, S., Jantus-Lewintre, E., & Bagan, J. (2021). Differentially methylated genes in proliferative verrucous leukoplakia reveal potential malignant biomarkers for oral squamous cell carcinoma. Oral oncology, 116105191. https://doi.org/10.1016/j.oraloncology.2021.105191
Herreros-Pomares, Alejandro, et al. "Differentially methylated genes in proliferative verrucous leukoplakia reveal potential malignant biomarkers for oral squamous cell carcinoma." Oral oncology vol. 116 (2021): 105191. doi: https://doi.org/10.1016/j.oraloncology.2021.105191
Herreros-Pomares A, Llorens C, Soriano B, Bagan L, Moreno A, Calabuig-Fariñas S, Jantus-Lewintre E, Bagan J. Differentially methylated genes in proliferative verrucous leukoplakia reveal potential malignant biomarkers for oral squamous cell carcinoma. Oral Oncol. 2021 May;116:105191. doi: 10.1016/j.oraloncology.2021.105191. Epub 2021 Feb 28. PMID: 33657465.
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Chemo-hydrodynamic pulsations in simple batch A + B → C systems.

The Journal of chemical physics

Budroni MA, Polo A, Upadhyay V, Bigaj A, Rongy L.
PMID: 33752375
J Chem Phys. 2021 Mar 21;154(11):114501. doi: 10.1063/5.0042560.

Spatio-temporal oscillations can be induced under batch conditions with ubiquitous bimolecular reactions in the absence of any nonlinear chemical feedback, thanks to an active interplay between the chemical process and chemically driven hydrodynamic flows. When two reactants A and...

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Budroni MA, Polo A, Upadhyay V, et al. Chemo-hydrodynamic pulsations in simple batch A + B → C systems. J Chem Phys. 2021;154(11):114501doi: 10.1063/5.0042560.
Budroni, M. A., Polo, A., Upadhyay, V., Bigaj, A., & Rongy, L. (2021). Chemo-hydrodynamic pulsations in simple batch A + B → C systems. The Journal of chemical physics, 154(11), 114501. https://doi.org/10.1063/5.0042560
Budroni, Marcello A, et al. "Chemo-hydrodynamic pulsations in simple batch A + B → C systems." The Journal of chemical physics vol. 154,11 (2021): 114501. doi: https://doi.org/10.1063/5.0042560
Budroni MA, Polo A, Upadhyay V, Bigaj A, Rongy L. Chemo-hydrodynamic pulsations in simple batch A + B → C systems. J Chem Phys. 2021 Mar 21;154(11):114501. doi: 10.1063/5.0042560. PMID: 33752375.
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How do we ensure diversity and maximise inclusion across all 10 surgical specialities?.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS

Khera B, Joseph M, Begaj A.
PMID: 34840116
J Plast Reconstr Aesthet Surg. 2021 Nov 15; doi: 10.1016/j.bjps.2021.11.031. Epub 2021 Nov 15.

No abstract available.

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Khera B, Joseph M, Begaj A. How do we ensure diversity and maximise inclusion across all 10 surgical specialities?. J Plast Reconstr Aesthet Surg. 2021;doi: 10.1016/j.bjps.2021.11.031.
Khera, B., Joseph, M., & Begaj, A. (2021). How do we ensure diversity and maximise inclusion across all 10 surgical specialities?. Journal of plastic, reconstructive & aesthetic surgery : JPRAS, . https://doi.org/10.1016/j.bjps.2021.11.031
Khera, Bhavika, et al. "How do we ensure diversity and maximise inclusion across all 10 surgical specialities?." Journal of plastic, reconstructive & aesthetic surgery : JPRAS vol. (2021). doi: https://doi.org/10.1016/j.bjps.2021.11.031
Khera B, Joseph M, Begaj A. How do we ensure diversity and maximise inclusion across all 10 surgical specialities?. J Plast Reconstr Aesthet Surg. 2021 Nov 15; doi: 10.1016/j.bjps.2021.11.031. Epub 2021 Nov 15. PMID: 34840116.
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Antidepressant activity of Spathodea campanulata in mice and predictive affinity of spatheosides towards type A monoamine oxidase.

Cellular and molecular biology (Noisy-le-Grand, France)

Bajaj J, Dwivedi J, Sahu R, Dave V, Verma K, Joshi S, Sati B, Sharma S, Seidel V, Mishra AP.
PMID: 34817375
Cell Mol Biol (Noisy-le-grand). 2021 Jan 31;67(1):1-8. doi: 10.14715/cmb/2021.67.1.1.

The antidepressant activity of Spathodea campanulata flowers was evaluated in mice and in silico. When tested at doses of 200 and 400 mg/kg, the methanol extract of S. campanulata (MESC) showed dose-dependent antidepressant activity in the force swim test...

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Bajaj J, Dwivedi J, Sahu R, et al. Antidepressant activity of Spathodea campanulata in mice and predictive affinity of spatheosides towards type A monoamine oxidase. Cell Mol Biol (Noisy-le-grand). 2021;67(1):1-8doi: 10.14715/cmb/2021.67.1.1.
Bajaj, J., Dwivedi, J., Sahu, R., Dave, V., Verma, K., Joshi, S., Sati, B., Sharma, S., Seidel, V., & Mishra, A. P. (2021). Antidepressant activity of Spathodea campanulata in mice and predictive affinity of spatheosides towards type A monoamine oxidase. Cellular and molecular biology (Noisy-le-Grand, France), 67(1), 1-8. https://doi.org/10.14715/cmb/2021.67.1.1
Bajaj, Jitendra, et al. "Antidepressant activity of Spathodea campanulata in mice and predictive affinity of spatheosides towards type A monoamine oxidase." Cellular and molecular biology (Noisy-le-Grand, France) vol. 67,1 (2021): 1-8. doi: https://doi.org/10.14715/cmb/2021.67.1.1
Bajaj J, Dwivedi J, Sahu R, Dave V, Verma K, Joshi S, Sati B, Sharma S, Seidel V, Mishra AP. Antidepressant activity of Spathodea campanulata in mice and predictive affinity of spatheosides towards type A monoamine oxidase. Cell Mol Biol (Noisy-le-grand). 2021 Jan 31;67(1):1-8. doi: 10.14715/cmb/2021.67.1.1. PMID: 34817375.
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DNA repair enzyme NEIL3 enables a stable neural representation of space by shaping transcription in hippocampal neurons.

iScience

Kunath N, Bugaj AM, Bigonah P, Fernandez-Berrocal MS, Bjørås M, Ye J.
PMID: 34988395
iScience. 2021 Nov 18;24(12):103470. doi: 10.1016/j.isci.2021.103470. eCollection 2021 Dec 17.

DNA repair enzymes are essential for the maintenance of the neuronal genome and thereby proper brain functions. Emerging evidence links DNA repair to epigenetic gene regulation; however, its contribution to different transcriptional programs required for neuronal functions remains elusive....

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Kunath N, Bugaj AM, Bigonah P, et al. DNA repair enzyme NEIL3 enables a stable neural representation of space by shaping transcription in hippocampal neurons. iScience. 2021;24(12):103470doi: 10.1016/j.isci.2021.103470.
Kunath, N., Bugaj, A. M., Bigonah, P., Fernandez-Berrocal, M. S., Bjørås, M., & Ye, J. (2021). DNA repair enzyme NEIL3 enables a stable neural representation of space by shaping transcription in hippocampal neurons. iScience, 24(12), 103470. https://doi.org/10.1016/j.isci.2021.103470
Kunath, Nicolas, et al. "DNA repair enzyme NEIL3 enables a stable neural representation of space by shaping transcription in hippocampal neurons." iScience vol. 24,12 (2021): 103470. doi: https://doi.org/10.1016/j.isci.2021.103470
Kunath N, Bugaj AM, Bigonah P, Fernandez-Berrocal MS, Bjørås M, Ye J. DNA repair enzyme NEIL3 enables a stable neural representation of space by shaping transcription in hippocampal neurons. iScience. 2021 Nov 18;24(12):103470. doi: 10.1016/j.isci.2021.103470. eCollection 2021 Dec 17. PMID: 34988395; PMCID: PMC8710552.
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TransRadial versus transUlnar artery approach for elective invasive percutaneous coronary interventions: a randomized trial on the feasibility and safety with ultrasonographic outcome - RAUL study.

Postepy w kardiologii interwencyjnej = Advances in interventional cardiology

Gralak-Lachowska D, Lewandowski PJ, Maciejewski P, Ramotowski B, Budaj A, Stec S.
PMID: 33598009
Postepy Kardiol Interwencyjnej. 2020 Dec;16(4):376-383. doi: 10.5114/aic.2020.101761. Epub 2020 Dec 29.

INTRODUCTION: Transradial access (TRA) for coronary angiography (CAG) and percutaneous coronary intervention (PCI) is superior to transfemoral access (TFA). Transulnar access (TUA) is an alternative to TRA.AIM: To compare the efficacy and safety of TRA vs. TUA in patients...

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Gralak-Lachowska D, Lewandowski PJ, Maciejewski P, et al. TransRadial versus transUlnar artery approach for elective invasive percutaneous coronary interventions: a randomized trial on the feasibility and safety with ultrasonographic outcome - RAUL study. Postepy Kardiol Interwencyjnej. 2020;16(4):376-383doi: 10.5114/aic.2020.101761.
Gralak-Lachowska, D., Lewandowski, P. J., Maciejewski, P., Ramotowski, B., Budaj, A., & Stec, S. (2020). TransRadial versus transUlnar artery approach for elective invasive percutaneous coronary interventions: a randomized trial on the feasibility and safety with ultrasonographic outcome - RAUL study. Postepy w kardiologii interwencyjnej = Advances in interventional cardiology, 16(4), 376-383. https://doi.org/10.5114/aic.2020.101761
Gralak-Lachowska, Dagmara, et al. "TransRadial versus transUlnar artery approach for elective invasive percutaneous coronary interventions: a randomized trial on the feasibility and safety with ultrasonographic outcome - RAUL study." Postepy w kardiologii interwencyjnej = Advances in interventional cardiology vol. 16,4 (2020): 376-383. doi: https://doi.org/10.5114/aic.2020.101761
Gralak-Lachowska D, Lewandowski PJ, Maciejewski P, Ramotowski B, Budaj A, Stec S. TransRadial versus transUlnar artery approach for elective invasive percutaneous coronary interventions: a randomized trial on the feasibility and safety with ultrasonographic outcome - RAUL study. Postepy Kardiol Interwencyjnej. 2020 Dec;16(4):376-383. doi: 10.5114/aic.2020.101761. Epub 2020 Dec 29. PMID: 33598009; PMCID: PMC7863831.
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Ultrasound to the Rescue: Management of Looped Guidewire during Hemodialysis Catheter Insertion in the Left Internal Jugular Vein.

Journal of medical ultrasound

Bajaj J, Khan MS.
PMID: 34729332
J Med Ultrasound. 2020 Nov 09;29(3):209-211. doi: 10.4103/JMU.JMU_99_20. eCollection 2021.

Hemodialysis catheters are commonly placed in the major central vein for the purpose of dialysis. Coiling or looping of guidewire is a rare but reported complication of a central vascular catheter insertion. We report a case in which we...

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Bajaj J, Khan MS. Ultrasound to the Rescue: Management of Looped Guidewire during Hemodialysis Catheter Insertion in the Left Internal Jugular Vein. J Med Ultrasound. 2020;29(3):209-211doi: 10.4103/JMU.JMU_99_20.
Bajaj, J., & Khan, M. S. (2021). Ultrasound to the Rescue: Management of Looped Guidewire during Hemodialysis Catheter Insertion in the Left Internal Jugular Vein. Journal of medical ultrasound, 29(3), 209-211. https://doi.org/10.4103/JMU.JMU_99_20
Bajaj, Jhanvi, and Khan, Mohammed Saif. "Ultrasound to the Rescue: Management of Looped Guidewire during Hemodialysis Catheter Insertion in the Left Internal Jugular Vein." Journal of medical ultrasound vol. 29,3 (2021): 209-211. doi: https://doi.org/10.4103/JMU.JMU_99_20
Bajaj J, Khan MS. Ultrasound to the Rescue: Management of Looped Guidewire during Hemodialysis Catheter Insertion in the Left Internal Jugular Vein. J Med Ultrasound. 2020 Nov 09;29(3):209-211. doi: 10.4103/JMU.JMU_99_20. eCollection 2021. PMID: 34729332; PMCID: PMC8515631.
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An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia.

Nature cancer

Bajaj J, Hamilton M, Shima Y, Chambers K, Spinler K, Van Nostrand EL, Yee BA, Blue SM, Chen M, Rizzeri D, Chuah C, Oehler VG, Broome HE, Sasik R, Scott-Browne J, Rao A, Yeo GW, Reya T.
PMID: 34109316
Nat Cancer. 2020 Apr;1(4):410-422. doi: 10.1038/s43018-020-0054-2. Epub 2020 Apr 20.

Aggressive myeloid leukemias such as blast crisis chronic myeloid leukemia and acute myeloid leukemia remain highly lethal. Here we report a genome-wide in vivo CRISPR screen to identify new dependencies in this disease. Among these, RNA-binding proteins (RBPs) in...

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Bajaj J, Hamilton M, Shima Y, et al. An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia. Nat Cancer. 2020;1(4):410-422doi: 10.1038/s43018-020-0054-2.
Bajaj, J., Hamilton, M., Shima, Y., Chambers, K., Spinler, K., Van Nostrand, E. L., Yee, B. A., Blue, S. M., Chen, M., Rizzeri, D., Chuah, C., Oehler, V. G., Broome, H. E., Sasik, R., Scott-Browne, J., Rao, A., Yeo, G. W., & Reya, T. (2020). An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia. Nature cancer, 1(4), 410-422. https://doi.org/10.1038/s43018-020-0054-2
Bajaj, Jeevisha, et al. "An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia." Nature cancer vol. 1,4 (2020): 410-422. doi: https://doi.org/10.1038/s43018-020-0054-2
Bajaj J, Hamilton M, Shima Y, Chambers K, Spinler K, Van Nostrand EL, Yee BA, Blue SM, Chen M, Rizzeri D, Chuah C, Oehler VG, Broome HE, Sasik R, Scott-Browne J, Rao A, Yeo GW, Reya T. An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia. Nat Cancer. 2020 Apr;1(4):410-422. doi: 10.1038/s43018-020-0054-2. Epub 2020 Apr 20. PMID: 34109316; PMCID: PMC8186448.
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Medical students' mental burden and experiences of voluntary work in COVID-19 patient support and treatment services: a qualitative analysis.

GMS journal for medical education

Nikendei C, Dinger-Ehrenthal U, Schumacher F, Bugaj TJ, Cranz A, Friedrich HC, Herpertz SC, Terhoeven V.
PMID: 34957325
GMS J Med Educ. 2021 Nov 15;38(7):Doc120. doi: 10.3205/zma001516. eCollection 2021.

No abstract available.

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Nikendei C, Dinger-Ehrenthal U, Schumacher F, et al. Medical students' mental burden and experiences of voluntary work in COVID-19 patient support and treatment services: a qualitative analysis. GMS J Med Educ. 2021;38(7):Doc120doi: 10.3205/zma001516.
Nikendei, C., Dinger-Ehrenthal, U., Schumacher, F., Bugaj, T. J., Cranz, A., Friedrich, H. C., Herpertz, S. C., & Terhoeven, V. (2021). Medical students' mental burden and experiences of voluntary work in COVID-19 patient support and treatment services: a qualitative analysis. GMS journal for medical education, 38(7), Doc120. https://doi.org/10.3205/zma001516
Nikendei, Christoph, et al. "Medical students' mental burden and experiences of voluntary work in COVID-19 patient support and treatment services: a qualitative analysis." GMS journal for medical education vol. 38,7 (2021): Doc120. doi: https://doi.org/10.3205/zma001516
Nikendei C, Dinger-Ehrenthal U, Schumacher F, Bugaj TJ, Cranz A, Friedrich HC, Herpertz SC, Terhoeven V. Medical students' mental burden and experiences of voluntary work in COVID-19 patient support and treatment services: a qualitative analysis. GMS J Med Educ. 2021 Nov 15;38(7):Doc120. doi: 10.3205/zma001516. eCollection 2021. PMID: 34957325; PMCID: PMC8675374.
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N-Arylation of Diketopyrrolopyrroles with Aryl Triflates.

Chemistry, an Asian journal

Gutkowski K, Skonieczny K, Bugaj M, Jacquemin D, Gryko DT.
PMID: 32154982
Chem Asian J. 2020 Apr 17;15(8):1369-1375. doi: 10.1002/asia.202000129. Epub 2020 Mar 24.

A new methodology for the double N-arylation of diketopyrrolopyrroles with aryl triflates has been developed. It is now possible to prepare diketopyrrolopyrroles bearing N-substituents derived from naphthalene, anthracene and coumarin in two steps from commercially available phenols. This represents...

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Gutkowski K, Skonieczny K, Bugaj M, et al. N-Arylation of Diketopyrrolopyrroles with Aryl Triflates. Chem Asian J. 2020;15(8):1369-1375doi: 10.1002/asia.202000129.
Gutkowski, K., Skonieczny, K., Bugaj, M., Jacquemin, D., & Gryko, D. T. (2020). N-Arylation of Diketopyrrolopyrroles with Aryl Triflates. Chemistry, an Asian journal, 15(8), 1369-1375. https://doi.org/10.1002/asia.202000129
Gutkowski, Krzysztof, et al. "N-Arylation of Diketopyrrolopyrroles with Aryl Triflates." Chemistry, an Asian journal vol. 15,8 (2020): 1369-1375. doi: https://doi.org/10.1002/asia.202000129
Gutkowski K, Skonieczny K, Bugaj M, Jacquemin D, Gryko DT. N-Arylation of Diketopyrrolopyrroles with Aryl Triflates. Chem Asian J. 2020 Apr 17;15(8):1369-1375. doi: 10.1002/asia.202000129. Epub 2020 Mar 24. PMID: 32154982.
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NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice.

Communications biology

Hildrestrand GA, Rolseth V, Kunath N, Suganthan R, Jensen V, Bugaj AM, Fernandez-Berrocal MS, Sikko SB, Vetlesen S, Kuśnierczyk A, Olsen AK, Gützkow KB, Rowe AD, Wang W, Moldestad O, Syrstad MD, Slupphaug G, Eide L, Klungland A, Sætrom P, Luna L, Ye J, Scheffler K, Bjørås M.
PMID: 34857879
Commun Biol. 2021 Dec 02;4(1):1354. doi: 10.1038/s42003-021-02864-x.

Oxidative DNA damage in the brain has been implicated in neurodegeneration and cognitive decline. DNA glycosylases initiate base excision repair (BER), the main pathway for oxidative DNA base lesion repair. NEIL1 and NEIL3 DNA glycosylases affect cognition in mice,...

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Hildrestrand GA, Rolseth V, Kunath N, et al. NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice. Commun Biol. 2021;4(1):1354doi: 10.1038/s42003-021-02864-x.
Hildrestrand, G. A., Rolseth, V., Kunath, N., Suganthan, R., Jensen, V., Bugaj, A. M., Fernandez-Berrocal, M. S., Sikko, S. B., Vetlesen, S., Kuśnierczyk, A., Olsen, A. K., Gützkow, K. B., Rowe, A. D., Wang, W., Moldestad, O., Syrstad, M. D., Slupphaug, G., Eide, L., Klungland, A., Sætrom, P., Luna, L., Ye, J., Scheffler, K., & Bjørås, M. (2021). NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice. Communications biology, 4(1), 1354. https://doi.org/10.1038/s42003-021-02864-x
Hildrestrand, Gunn A, et al. "NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice." Communications biology vol. 4,1 (2021): 1354. doi: https://doi.org/10.1038/s42003-021-02864-x
Hildrestrand GA, Rolseth V, Kunath N, Suganthan R, Jensen V, Bugaj AM, Fernandez-Berrocal MS, Sikko SB, Vetlesen S, Kuśnierczyk A, Olsen AK, Gützkow KB, Rowe AD, Wang W, Moldestad O, Syrstad MD, Slupphaug G, Eide L, Klungland A, Sætrom P, Luna L, Ye J, Scheffler K, Bjørås M. NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice. Commun Biol. 2021 Dec 02;4(1):1354. doi: 10.1038/s42003-021-02864-x. PMID: 34857879; PMCID: PMC8639745.
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Basilar Invagination and Atlantoaxial Dislocation: Reduction, Deformity Correction and Realignment Using the DCER (Distraction, Compression, Extension, and Reduction) Technique With Customized Instrumentation and Implants.

Neurospine

Sarat Chandra P, Bajaj J, Singh PK, Garg K, Agarwal D.
PMID: 31261462
Neurospine. 2019 Jun;16(2):231-250. doi: 10.14245/ns.1938194.097. Epub 2019 Jun 30.

OBJECTIVE: The technique of distraction, compression, extension, and reduction (DCER) is effective to reduce, realign, and relieve cranio-spinal compression through posterior only approach.METHODS: Study included all patients with atlantoaxial dislocation and basilar invagination (BI) with occipitalized C1 arch. Study...

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Sarat Chandra P, Bajaj J, Singh PK, et al. Basilar Invagination and Atlantoaxial Dislocation: Reduction, Deformity Correction and Realignment Using the DCER (Distraction, Compression, Extension, and Reduction) Technique With Customized Instrumentation and Implants. Neurospine. 2019;16(2):231-250doi: 10.14245/ns.1938194.097.
Sarat Chandra, P., Bajaj, J., Singh, P. K., Garg, K., & Agarwal, D. (2019). Basilar Invagination and Atlantoaxial Dislocation: Reduction, Deformity Correction and Realignment Using the DCER (Distraction, Compression, Extension, and Reduction) Technique With Customized Instrumentation and Implants. Neurospine, 16(2), 231-250. https://doi.org/10.14245/ns.1938194.097
Sarat Chandra, P, et al. "Basilar Invagination and Atlantoaxial Dislocation: Reduction, Deformity Correction and Realignment Using the DCER (Distraction, Compression, Extension, and Reduction) Technique With Customized Instrumentation and Implants." Neurospine vol. 16,2 (2019): 231-250. doi: https://doi.org/10.14245/ns.1938194.097
Sarat Chandra P, Bajaj J, Singh PK, Garg K, Agarwal D. Basilar Invagination and Atlantoaxial Dislocation: Reduction, Deformity Correction and Realignment Using the DCER (Distraction, Compression, Extension, and Reduction) Technique With Customized Instrumentation and Implants. Neurospine. 2019 Jun;16(2):231-250. doi: 10.14245/ns.1938194.097. Epub 2019 Jun 30. PMID: 31261462; PMCID: PMC6603831.
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