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Showing 25 to 36 of 79 entries
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Selecting Target Antigens for Cancer Vaccine Development.

Vaccines

Buonaguro L, Tagliamonte M.
PMID: 33080888
Vaccines (Basel). 2020 Oct 17;8(4). doi: 10.3390/vaccines8040615.

One of the principal goals of cancer immunotherapy is the development of efficient therapeutic cancer vaccines that are able to elicit an effector as well as memory T cell response specific to tumor antigens. In recent years, the attention...

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Buonaguro L, Tagliamonte M. Selecting Target Antigens for Cancer Vaccine Development. Vaccines (Basel). 2020;8(4)doi: 10.3390/vaccines8040615.
Buonaguro, L., & Tagliamonte, M. (2020). Selecting Target Antigens for Cancer Vaccine Development. Vaccines, 8(4), . https://doi.org/10.3390/vaccines8040615
Buonaguro, Luigi, and Tagliamonte, Maria. "Selecting Target Antigens for Cancer Vaccine Development." Vaccines vol. 8,4 (2020). doi: https://doi.org/10.3390/vaccines8040615
Buonaguro L, Tagliamonte M. Selecting Target Antigens for Cancer Vaccine Development. Vaccines (Basel). 2020 Oct 17;8(4). doi: 10.3390/vaccines8040615. PMID: 33080888; PMCID: PMC7711972.
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The Role of circRNAs in Human Papillomavirus (HPV)-Associated Cancers.

Cancers

Bonelli P, Borrelli A, Tuccillo FM, Buonaguro FM, Tornesello ML.
PMID: 33803232
Cancers (Basel). 2021 Mar 09;13(5). doi: 10.3390/cancers13051173.

Circular RNAs (circRNAs) are a new class of "non-coding RNAs" that originate from non-sequential back-splicing of exons and/or introns of precursor messenger RNAs (pre-mRNAs). These molecules are generally produced at low levels in a cell-type-specific manner in mammalian tissues,...

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Bonelli P, Borrelli A, Tuccillo FM, et al. The Role of circRNAs in Human Papillomavirus (HPV)-Associated Cancers. Cancers (Basel). 2021;13(5)doi: 10.3390/cancers13051173.
Bonelli, P., Borrelli, A., Tuccillo, F. M., Buonaguro, F. M., & Tornesello, M. L. (2021). The Role of circRNAs in Human Papillomavirus (HPV)-Associated Cancers. Cancers, 13(5), . https://doi.org/10.3390/cancers13051173
Bonelli, Patrizia, et al. "The Role of circRNAs in Human Papillomavirus (HPV)-Associated Cancers." Cancers vol. 13,5 (2021). doi: https://doi.org/10.3390/cancers13051173
Bonelli P, Borrelli A, Tuccillo FM, Buonaguro FM, Tornesello ML. The Role of circRNAs in Human Papillomavirus (HPV)-Associated Cancers. Cancers (Basel). 2021 Mar 09;13(5). doi: 10.3390/cancers13051173. PMID: 33803232; PMCID: PMC7963196.
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Human Papillomavirus and Cancers.

Cancers

Tornesello ML, Buonaguro FM.
PMID: 33333750
Cancers (Basel). 2020 Dec 15;12(12). doi: 10.3390/cancers12123772.

Persistent infection with oncogenic human papillomaviruses (HPVs) is the main cause of nearly all cervical cancers as well as of a significant proportion of other malignancies arising from the mucosal squamous epithelia of the anogenital tract as well as...

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Tornesello ML, Buonaguro FM. Human Papillomavirus and Cancers. Cancers (Basel). 2020;12(12)doi: 10.3390/cancers12123772.
Tornesello, M. L., & Buonaguro, F. M. (2020). Human Papillomavirus and Cancers. Cancers, 12(12), . https://doi.org/10.3390/cancers12123772
Tornesello, Maria Lina, and Buonaguro, Franco M. "Human Papillomavirus and Cancers." Cancers vol. 12,12 (2020). doi: https://doi.org/10.3390/cancers12123772
Tornesello ML, Buonaguro FM. Human Papillomavirus and Cancers. Cancers (Basel). 2020 Dec 15;12(12). doi: 10.3390/cancers12123772. PMID: 33333750; PMCID: PMC7765250.
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Human Hepatocellular Carcinoma (HCC).

Cancers

Buonaguro L.
PMID: 33322652
Cancers (Basel). 2020 Dec 12;12(12). doi: 10.3390/cancers12123739.

Hepatocellular carcinoma (HCC) is the fifth most common cancer and accounts for 8 [...].

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Buonaguro L. Human Hepatocellular Carcinoma (HCC). Cancers (Basel). 2020;12(12)doi: 10.3390/cancers12123739.
Buonaguro, L. (2020). Human Hepatocellular Carcinoma (HCC). Cancers, 12(12), . https://doi.org/10.3390/cancers12123739
Buonaguro, Luigi. "Human Hepatocellular Carcinoma (HCC)." Cancers vol. 12,12 (2020). doi: https://doi.org/10.3390/cancers12123739
Buonaguro L. Human Hepatocellular Carcinoma (HCC). Cancers (Basel). 2020 Dec 12;12(12). doi: 10.3390/cancers12123739. PMID: 33322652; PMCID: PMC7763211.
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Induction of Rosette-to-Lumen stage embryoids using reprogramming paradigms in ESCs.

Nature communications

Langkabel J, Horne A, Bonaguro L, Holsten L, Hesse T, Knaus A, Riedel Y, Becker M, Händler K, Elmzzahi T, Bassler K, Reusch N, Yeghiazarian LH, Pecht T, Saglam A, Ulas T, Aschenbrenner AC, Kaiser F, Kubaczka C, Schultze JL, Schorle H.
PMID: 34916498
Nat Commun. 2021 Dec 16;12(1):7322. doi: 10.1038/s41467-021-27586-w.

Blastocyst-derived stem cell lines were shown to self-organize into embryo-like structures in 3D cell culture environments. Here, we provide evidence that embryo-like structures can be generated solely based on transcription factor-mediated reprogramming of embryonic stem cells in a simple...

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Langkabel J, Horne A, Bonaguro L, et al. Induction of Rosette-to-Lumen stage embryoids using reprogramming paradigms in ESCs. Nat Commun. 2021;12(1):7322doi: 10.1038/s41467-021-27586-w.
Langkabel, J., Horne, A., Bonaguro, L., Holsten, L., Hesse, T., Knaus, A., Riedel, Y., Becker, M., Händler, K., Elmzzahi, T., Bassler, K., Reusch, N., Yeghiazarian, L. H., Pecht, T., Saglam, A., Ulas, T., Aschenbrenner, A. C., Kaiser, F., Kubaczka, C., Schultze, J. L., & Schorle, H. (2021). Induction of Rosette-to-Lumen stage embryoids using reprogramming paradigms in ESCs. Nature communications, 12(1), 7322. https://doi.org/10.1038/s41467-021-27586-w
Langkabel, Jan, et al. "Induction of Rosette-to-Lumen stage embryoids using reprogramming paradigms in ESCs." Nature communications vol. 12,1 (2021): 7322. doi: https://doi.org/10.1038/s41467-021-27586-w
Langkabel J, Horne A, Bonaguro L, Holsten L, Hesse T, Knaus A, Riedel Y, Becker M, Händler K, Elmzzahi T, Bassler K, Reusch N, Yeghiazarian LH, Pecht T, Saglam A, Ulas T, Aschenbrenner AC, Kaiser F, Kubaczka C, Schultze JL, Schorle H. Induction of Rosette-to-Lumen stage embryoids using reprogramming paradigms in ESCs. Nat Commun. 2021 Dec 16;12(1):7322. doi: 10.1038/s41467-021-27586-w. PMID: 34916498.
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Novel Molecular Targets for Hepatocellular Carcinoma.

Cancers

Cavalluzzo B, Mauriello A, Ragone C, Manolio C, Tornesello ML, Buonaguro FM, Tvingsholm SA, Hadrup SR, Tagliamonte M, Buonaguro L.
PMID: 35008303
Cancers (Basel). 2021 Dec 28;14(1). doi: 10.3390/cancers14010140.

Hepatocellular carcinoma (HCC) is the third leading cause of death from cancer globally. Indeed, only a few treatments are available, most of which are effective only for the early stages of the disease. Therefore, there is an urgent needing...

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Cavalluzzo B, Mauriello A, Ragone C, et al. Novel Molecular Targets for Hepatocellular Carcinoma. Cancers (Basel). 2021;14(1)doi: 10.3390/cancers14010140.
Cavalluzzo, B., Mauriello, A., Ragone, C., Manolio, C., Tornesello, M. L., Buonaguro, F. M., Tvingsholm, S. A., Hadrup, S. R., Tagliamonte, M., & Buonaguro, L. (2021). Novel Molecular Targets for Hepatocellular Carcinoma. Cancers, 14(1), . https://doi.org/10.3390/cancers14010140
Cavalluzzo, Beatrice, et al. "Novel Molecular Targets for Hepatocellular Carcinoma." Cancers vol. 14,1 (2021). doi: https://doi.org/10.3390/cancers14010140
Cavalluzzo B, Mauriello A, Ragone C, Manolio C, Tornesello ML, Buonaguro FM, Tvingsholm SA, Hadrup SR, Tagliamonte M, Buonaguro L. Novel Molecular Targets for Hepatocellular Carcinoma. Cancers (Basel). 2021 Dec 28;14(1). doi: 10.3390/cancers14010140. PMID: 35008303; PMCID: PMC8750630.
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Clinical assessment of endothelial function in heart failure with preserved ejection fraction: A meta-analysis with meta-regressions.

European journal of clinical investigation

Ambrosino P, Papa A, Buonauro A, Mosella M, Calcaterra I, Spedicato GA, Maniscalco M, Di Minno MND.
PMID: 33749828
Eur J Clin Invest. 2021 Aug;51(8):e13552. doi: 10.1111/eci.13552. Epub 2021 May 22.

BACKGROUND: Endothelial dysfunction is a key mechanism in the development of cardiac remodelling and diastolic dysfunction in heart failure with preserved ejection fraction (HFpEF). Flow-mediated (FMD) and nitrate-mediated dilation (NMD) are noninvasive methods to assess endothelial function. We performed...

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Ambrosino P, Papa A, Buonauro A, et al. Clinical assessment of endothelial function in heart failure with preserved ejection fraction: A meta-analysis with meta-regressions. Eur J Clin Invest. 2021;51(8):e13552doi: 10.1111/eci.13552.
Ambrosino, P., Papa, A., Buonauro, A., Mosella, M., Calcaterra, I., Spedicato, G. A., Maniscalco, M., & Di Minno, M. N. D. (2021). Clinical assessment of endothelial function in heart failure with preserved ejection fraction: A meta-analysis with meta-regressions. European journal of clinical investigation, 51(8), e13552. https://doi.org/10.1111/eci.13552
Ambrosino, Pasquale, et al. "Clinical assessment of endothelial function in heart failure with preserved ejection fraction: A meta-analysis with meta-regressions." European journal of clinical investigation vol. 51,8 (2021): e13552. doi: https://doi.org/10.1111/eci.13552
Ambrosino P, Papa A, Buonauro A, Mosella M, Calcaterra I, Spedicato GA, Maniscalco M, Di Minno MND. Clinical assessment of endothelial function in heart failure with preserved ejection fraction: A meta-analysis with meta-regressions. Eur J Clin Invest. 2021 Aug;51(8):e13552. doi: 10.1111/eci.13552. Epub 2021 May 22. PMID: 33749828.
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Long-term memory T cells as preventive anticancer immunity elicited by TuA-derived heteroclitic peptides.

Journal of translational medicine

Mauriello A, Cavalluzzo B, Manolio C, Ragone C, Luciano A, Barbieri A, Tornesello ML, Buonaguro FM, Tagliamonte M, Buonaguro L.
PMID: 34952611
J Transl Med. 2021 Dec 24;19(1):526. doi: 10.1186/s12967-021-03194-6.

The host's immune system may be primed against antigens during the lifetime (e.g. microorganisms antigens-MoAs), and swiftly recalled upon growth of a tumor expressing antigens similar in sequence and structure. C57BL/6 mice were immunized in a preventive setting with...

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Mauriello A, Cavalluzzo B, Manolio C, et al. Long-term memory T cells as preventive anticancer immunity elicited by TuA-derived heteroclitic peptides. J Transl Med. 2021;19(1):526doi: 10.1186/s12967-021-03194-6.
Mauriello, A., Cavalluzzo, B., Manolio, C., Ragone, C., Luciano, A., Barbieri, A., Tornesello, M. L., Buonaguro, F. M., Tagliamonte, M., & Buonaguro, L. (2021). Long-term memory T cells as preventive anticancer immunity elicited by TuA-derived heteroclitic peptides. Journal of translational medicine, 19(1), 526. https://doi.org/10.1186/s12967-021-03194-6
Mauriello, Angela, et al. "Long-term memory T cells as preventive anticancer immunity elicited by TuA-derived heteroclitic peptides." Journal of translational medicine vol. 19,1 (2021): 526. doi: https://doi.org/10.1186/s12967-021-03194-6
Mauriello A, Cavalluzzo B, Manolio C, Ragone C, Luciano A, Barbieri A, Tornesello ML, Buonaguro FM, Tagliamonte M, Buonaguro L. Long-term memory T cells as preventive anticancer immunity elicited by TuA-derived heteroclitic peptides. J Transl Med. 2021 Dec 24;19(1):526. doi: 10.1186/s12967-021-03194-6. PMID: 34952611.
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Molecular and phylogenetic analysis of HIV-1 variants circulating among injecting drug users in Mashhad-Iran.

Infectious agents and cancer

Naderi HR, Tagliamonte M, Tornesello ML, Ciccozzi M, Rezza G, Farid R, Buonaguro FM, Buonaguro L.
PMID: 17150133
Infect Agent Cancer. 2006 Sep 19;1:4. doi: 10.1186/1750-9378-1-4.

Genetic and phylogenetic information on the HIV-1 epidemic in Middle-East Countries, and in particular in Iran, are extremely limited. By March 2004, the Iranian Ministry of Health officially reported a cumulative number of 6'532 HIV positive individuals and 214...

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Naderi HR, Tagliamonte M, Tornesello ML, et al. Molecular and phylogenetic analysis of HIV-1 variants circulating among injecting drug users in Mashhad-Iran. Infect Agent Cancer. 2006;1:4doi: 10.1186/1750-9378-1-4.
Naderi, H. R., Tagliamonte, M., Tornesello, M. L., Ciccozzi, M., Rezza, G., Farid, R., Buonaguro, F. M., & Buonaguro, L. (2006). Molecular and phylogenetic analysis of HIV-1 variants circulating among injecting drug users in Mashhad-Iran. Infectious agents and cancer, 14. https://doi.org/10.1186/1750-9378-1-4
Naderi, H R, et al. "Molecular and phylogenetic analysis of HIV-1 variants circulating among injecting drug users in Mashhad-Iran." Infectious agents and cancer vol. 1 (2006): 4. doi: https://doi.org/10.1186/1750-9378-1-4
Naderi HR, Tagliamonte M, Tornesello ML, Ciccozzi M, Rezza G, Farid R, Buonaguro FM, Buonaguro L. Molecular and phylogenetic analysis of HIV-1 variants circulating among injecting drug users in Mashhad-Iran. Infect Agent Cancer. 2006 Sep 19;1:4. doi: 10.1186/1750-9378-1-4. PMID: 17150133; PMCID: PMC1635003.
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Extracellular vesicles produced by primary human keratinocytes in response to TLR agonists induce stimulus-specific responses in antigen-presenting cells.

Cellular signalling

Papayannakos CJ, DeVoti JA, Israr M, Alsudani H, Bonagura V, Steinberg BM.
PMID: 33781846
Cell Signal. 2021 Jul;83:109994. doi: 10.1016/j.cellsig.2021.109994. Epub 2021 Mar 27.

Cells can communicate through the extracellular vesicles (EVs) they secrete. Pathogen associated molecular patterns (PAMPs), alter the biophysical and communicative properties of EVs released from cells, but the functional consequences of these changes are unknown. Characterization of keratinocyte-derived EVs...

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Papayannakos CJ, DeVoti JA, Israr M, et al. Extracellular vesicles produced by primary human keratinocytes in response to TLR agonists induce stimulus-specific responses in antigen-presenting cells. Cell Signal. 2021;83:109994doi: 10.1016/j.cellsig.2021.109994.
Papayannakos, C. J., DeVoti, J. A., Israr, M., Alsudani, H., Bonagura, V., & Steinberg, B. M. (2021). Extracellular vesicles produced by primary human keratinocytes in response to TLR agonists induce stimulus-specific responses in antigen-presenting cells. Cellular signalling, 83109994. https://doi.org/10.1016/j.cellsig.2021.109994
Papayannakos, Christopher J, et al. "Extracellular vesicles produced by primary human keratinocytes in response to TLR agonists induce stimulus-specific responses in antigen-presenting cells." Cellular signalling vol. 83 (2021): 109994. doi: https://doi.org/10.1016/j.cellsig.2021.109994
Papayannakos CJ, DeVoti JA, Israr M, Alsudani H, Bonagura V, Steinberg BM. Extracellular vesicles produced by primary human keratinocytes in response to TLR agonists induce stimulus-specific responses in antigen-presenting cells. Cell Signal. 2021 Jul;83:109994. doi: 10.1016/j.cellsig.2021.109994. Epub 2021 Mar 27. PMID: 33781846; PMCID: PMC8091864.
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Classification of weakly carcinogenic human papillomavirus types: addressing the limits of epidemiology at the borderline.

Infectious agents and cancer

Schiffman M, Clifford G, Buonaguro FM.
PMID: 19486508
Infect Agent Cancer. 2009 Jun 01;4:8. doi: 10.1186/1750-9378-4-8.

Virtually all cases of cervical cancer are caused by persistent infections with a restricted set of human papillomaviruses (HPV). Some HPV types, like HPV16 and HPV18, are clear and powerful carcinogens. However, the categorization of the most weakly carcinogenic...

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Schiffman M, Clifford G, Buonaguro FM. Classification of weakly carcinogenic human papillomavirus types: addressing the limits of epidemiology at the borderline. Infect Agent Cancer. 2009;4:8doi: 10.1186/1750-9378-4-8.
Schiffman, M., Clifford, G., & Buonaguro, F. M. (2009). Classification of weakly carcinogenic human papillomavirus types: addressing the limits of epidemiology at the borderline. Infectious agents and cancer, 48. https://doi.org/10.1186/1750-9378-4-8
Schiffman, Mark, et al. "Classification of weakly carcinogenic human papillomavirus types: addressing the limits of epidemiology at the borderline." Infectious agents and cancer vol. 4 (2009): 8. doi: https://doi.org/10.1186/1750-9378-4-8
Schiffman M, Clifford G, Buonaguro FM. Classification of weakly carcinogenic human papillomavirus types: addressing the limits of epidemiology at the borderline. Infect Agent Cancer. 2009 Jun 01;4:8. doi: 10.1186/1750-9378-4-8. PMID: 19486508; PMCID: PMC2694995.
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Gene Therapy of Glioblastoma Multiforme with a Bicistronic Retroviral Vector Expressing Human IL-2 and HSV-tK.

Methods in molecular medicine

Palù G, Pizzato M, Bonaguro R, Colombo F.
PMID: 21390827
Methods Mol Med. 2000;35:511-22. doi: 10.1385/1-59259-086-1:511.

Gene therapy of cancer includes strategies for augmentation of immunotherapeutic and chemoterapeutic approaches. These strategies mainly involve ex vivo and in vivo cytokine gene transfer, drug sensitization with genes for prodrug delivery, and the use of drug-resistance genes for...

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Palù G, Pizzato M, Bonaguro R, et al. Gene Therapy of Glioblastoma Multiforme with a Bicistronic Retroviral Vector Expressing Human IL-2 and HSV-tK. Methods Mol Med. 2000;35:511-22doi: 10.1385/1-59259-086-1:511.
Palù, G., Pizzato, M., Bonaguro, R., & Colombo, F. (2000). Gene Therapy of Glioblastoma Multiforme with a Bicistronic Retroviral Vector Expressing Human IL-2 and HSV-tK. Methods in molecular medicine, 35511-22. https://doi.org/10.1385/1-59259-086-1:511
Palù, G, et al. "Gene Therapy of Glioblastoma Multiforme with a Bicistronic Retroviral Vector Expressing Human IL-2 and HSV-tK." Methods in molecular medicine vol. 35 (2000): 511-22. doi: https://doi.org/10.1385/1-59259-086-1:511
Palù G, Pizzato M, Bonaguro R, Colombo F. Gene Therapy of Glioblastoma Multiforme with a Bicistronic Retroviral Vector Expressing Human IL-2 and HSV-tK. Methods Mol Med. 2000;35:511-22. doi: 10.1385/1-59259-086-1:511. PMID: 21390827.
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Showing 25 to 36 of 79 entries