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Showing 25 to 36 of 134 entries
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The Living with Pulmonary Fibrosis questionnaire in progressive fibrosing interstitial lung disease.

ERJ open research

Swigris J, Cutts K, Male N, Baldwin M, Rohr KB, Bushnell DM.
PMID: 34046493
ERJ Open Res. 2021 May 24;7(2). doi: 10.1183/23120541.00145-2020. eCollection 2021 Apr.

The Living with Idiopathic Pulmonary Fibrosis (L-IPF) questionnaire was developed with substantial input from patients with idiopathic pulmonary fibrosis (IPF) to assess symptoms and health-related quality of life (HRQoL). Because IPF is the prototypical chronic fibrosing interstitial lung disease...

Increased Levels of IL-16 in the Central Nervous System during Neuroinflammation Are Associated with Infiltrating Immune Cells and Resident Glial Cells.

Biology

Hridi SU, Barbour M, Wilson C, Franssen AJ, Harte T, Bushell TJ, Jiang HR.
PMID: 34071825
Biology (Basel). 2021 May 27;10(6). doi: 10.3390/biology10060472.

Interleukin (IL)-16, a CD4

SiPP (Stroke in Pregnancy and Postpartum): A prospective, observational, international, multicentre study on pathophysiological mechanisms, clinical profile, management and outcome of cerebrovascular diseases in pregnant and postpartum women.

European stroke journal

Lorenzano S, Kremer C, Pavlovic A, Jovanovic DR, Sandset EC, Christensen H, Bushnell C, Arsovska A, Sprigg N, Roffe C, Ijäs P, Gdovinova Z, Alexandrov A, Zedde M, Tassi R, Acciaresi M, Lantz M, Sunnerhagen K, Zarkov M, Rantanen K, Perren F, Iversen HK, Kruuse C, Slowik A, Palazzo P, Korv J, Fromm A, Lovrencic-Huzjan A, Korompoki E, Fonseca AC, Gall SL, Brunner F, Caso V, Sacco S.
PMID: 32637653
Eur Stroke J. 2020 Jun;5(2):193-203. doi: 10.1177/2396987319893512. Epub 2019 Dec 06.

RATIONALE: Cerebrovascular diseases associated with pregnancy and postpartum period are uncommon; however, they can have an important impact on health of both women and foetus or newborn.AIMS: To evaluate the frequency, characteristics and management of cerebrovascular events in pregnant/postpartum...

Gold nanoparticles and tilt pairs to assess protein flexibility by cryo-electron microscopy.

Ultramicroscopy

Jagota M, Townshend RJL, Kang LW, Bushnell DA, Dror RO, Kornberg RD, Azubel M.
PMID: 34062386
Ultramicroscopy. 2021 Aug;227:113302. doi: 10.1016/j.ultramic.2021.113302. Epub 2021 May 04.

A computational method was developed to recover the three-dimensional coordinates of gold nanoparticles specifically attached to a protein complex from tilt-pair images collected by electron microscopy. The program was tested on a simulated dataset and applied to a real...

Consistently High Agreement Between Independent Raters of Niemann-Pick Type C1 Clinical Severity Scale in Phase 2/3 Trial.

Pediatric neurology

Farhat N, Bailey L, Friedmann K, Bushnell DM, Rodriguez D, Berry-Kravis E, Porter FD.
PMID: 34952292
Pediatr Neurol. 2021 Nov 29;127:32-38. doi: 10.1016/j.pediatrneurol.2021.11.009. Epub 2021 Nov 29.

BACKGROUND: Niemann-Pick disease, type C1 (NPC1) is a rare neurodegenerative genetic disorder characterized by impaired intracellular transport of cholesterol and other lipids. The Niemann-Pick Disease, type C1 Severity Scale (NPC-SS) was developed to quantify neurological progression of NPC; it...

Patient Factors Associated With Attendance at a Comprehensive Postacute Stroke Visit: Insight From the Vanguard Site.

Archives of rehabilitation research and clinical translation

Halladay J, Bushnell C, Psioda M, Jones S, Lycan S, Condon C, Xenakis J, Prvu-Bettger J.
PMID: 33543066
Arch Rehabil Res Clin Transl. 2019 Dec 21;2(1):100037. doi: 10.1016/j.arrct.2019.100037. eCollection 2020 Mar.

OBJECTIVE: To understand the patient-influenced activities and characteristics associated with return to a single postacute care transitional care clinic visit in a cohort of patients cared for at the test health system site of the larger Comprehensive Post-Acute Stroke...

Role of epigenetics in unicellular to multicellular transition in Dictyostelium.

Genome biology

Wang SY, Pollina EA, Wang IH, Pino LK, Bushnell HL, Takashima K, Fritsche C, Sabin G, Garcia BA, Greer PL, Greer EL.
PMID: 33947439
Genome Biol. 2021 May 04;22(1):134. doi: 10.1186/s13059-021-02360-9.

BACKGROUND: The evolution of multicellularity is a critical event that remains incompletely understood. We use the social amoeba, Dictyostelium discoideum, one of the rare organisms that readily transits back and forth between both unicellular and multicellular stages, to examine...

Differential effects of morphine on pain and temperature perception in human volunteers.

European journal of pain (London, England)

Morin C, Duncan GH, Lavigne G, Boily JG, Bushnell MC.
PMID: 10700347
Eur J Pain. 1999 Jun;3(3):193-204. doi: 10.1053/eujp.1999.0131.

Electrophysiological and behavioral evidence suggests that morphine may have a differential effect on nociceptive and thermal pathways. In this study, we explored the perceptual consequences of these differential actions by examining the effect of a low morphine dose (0.08...

Signal detection behavior in humans and rats: a comparison with matched tasks.

Behavioural processes

Bushnell PJ, Benignus VA, Case MW.
PMID: 12915002
Behav Processes. 2003 Aug 29;64(1):121-129. doi: 10.1016/s0376-6357(03)00146-3.

Animal models of human cognitive processes are essential for studying the neurobiological mechanisms of these processes and for developing therapies for intoxication and neurodegenerative diseases. A discrete-trial signal detection task was developed for assessing sustained attention in rats; a...

Density Functional Theory Study of the Capture and Release of Carbon Dioxide by Benzyl-Disulfide, -Diselenide, and -Ditelluride.

The journal of physical chemistry. A

Harris D, Bushnell E.
PMID: 30908046
J Phys Chem A. 2019 Apr 18;123(15):3383-3388. doi: 10.1021/acs.jpca.9b01862. Epub 2019 Apr 04.

Rising levels of CO

Corrigendum: Double-flow focused liquid injector for efficient serial femtosecond crystallography.

Scientific reports

Oberthuer D, Knoška J, Wiedorn MO, Beyerlein KR, Bushnell DA, Kovaleva EG, Heymann M, Gumprecht L, Kirian RA, Barty A, Mariani V, Tolstikova A, Adriano L, Awel S, Barthelmess M, Dörner K, Xavier PL, Yefanov O, James DR, Nelson G, Wang D, Calvey G, Chen Y, Schmidt A, Szczepek M, Frielingsdorf S, Lenz O, Snell E, Robinson PJ, Šarler B, Belšak G, Maček M, Wilde F, Aquila A, Boutet S, Liang M, Hunter MS, Scheerer P, Lipscomb JD, Weierstall U, Kornberg RD, Spence JCH, Pollack L, Chapman HN, Bajt S.
PMID: 28635955
Sci Rep. 2017 Jun 21;7:46846. doi: 10.1038/srep46846.

This corrects the article DOI: 10.1038/srep44628.

Effects of Triflusal and Clopidogrel on the Secondary Prevention of Stroke Based on Cytochrome P450 2C19 Genotyping.

Journal of stroke

Han SW, Kim YJ, Ahn SH, Seo WK, Yu S, Oh SH, Nam HS, Choi HY, Yoon SS, Kim SH, Lee JY, Lee JH, Hwang YH, Lee KO, Jung YH, Lee J, Sohn SI, Kim YN, Lee KA, Bushnell CD, Lee KY.
PMID: 29037010
J Stroke. 2017 Sep;19(3):356-364. doi: 10.5853/jos.2017.01249. Epub 2017 Sep 29.

BACKGROUND AND PURPOSE: To compare the efficacy and safety of antiplatelet agents for the secondary prevention of ischemic stroke based on cytochrome P450 2C19 (CYP2C19) polymorphisms.METHODS: This study was a prospective, multicenter, randomized, parallel-group, open-label, blind genotype trial. First...

Showing 25 to 36 of 134 entries