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Showing 397 to 404 of 404 entries
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Patient-Centered Identification of Meaningful Regulatory Endpoints for Medical Devices to Treat Parkinson's Disease.

MDM policy & practice

Benz HL, Caldwell B, Ruiz JP, Saha A, Ho M, Christopher S, Bardot D, Sheehan M, Donnelly A, McLaughlin L, Mange B, Hauber AB, Gwinn K, Heetderks WJ, Sheldon M.
PMID: 34277950
MDM Policy Pract. 2021 Jul 02;6(1):23814683211021380. doi: 10.1177/23814683211021380. eCollection 2021.

No abstract available.

Amelioration of Alzheimer's disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow.

Nature biomedical engineering

Xie C, Zhuang XX, Niu Z, Ai R, Lautrup S, Zheng S, Jiang Y, Han R, Gupta TS, Cao S, Lagartos-Donate MJ, Cai CZ, Xie LM, Caponio D, Wang WW, Schmauck-Medina T, Zhang J, Wang HL, Lou G, Xiao X, Zheng W, Palikaras K, Yang G, Caldwell KA, Caldwell GA, Shen HM, Nilsen H, Lu JH, Fang EF.
PMID: 34992270
Nat Biomed Eng. 2022 Jan 06; doi: 10.1038/s41551-021-00819-5. Epub 2022 Jan 06.

A reduced removal of dysfunctional mitochondria is common to aging and age-related neurodegenerative pathologies such as Alzheimer's disease (AD). Strategies for treating such impaired mitophagy would benefit from the identification of mitophagy modulators. Here we report the combined use...

Comparison of endovascular strategy versus hybrid procedure in treatment of chronic venous obstructions involving the confluence of common femoral vein.

Journal of vascular surgery. Venous and lymphatic disorders

Piao L, Barbati ME, Shekarchian S, Jacobs MJ, Razavi M, Rass K, Jalaie H, Caldwell G, Bilandzic M, Foth M.
PMID: 34478907
J Vasc Surg Venous Lymphat Disord. 2021 Aug 31; doi: 10.1016/j.jvsv.2021.08.016. Epub 2021 Aug 31.

OBJECTIVE: Treatment of extensive chronic venous obstruction (CVO) with post-thrombotic trabeculation involving the common femoral vein with extension into the femoral vein or deep femoral vein remains a challenge and the best treatment technique for such cases is not...

A Survey of Clinical Usage of Non-steroidal Intra-Articular Therapeutics by Equine Practitioners.

Frontiers in veterinary science

Velloso Alvarez A, Boone LH, Braim AP, Taintor JS, Caldwell F, Wright JC, Wooldridge AA.
PMID: 33195592
Front Vet Sci. 2020 Oct 22;7:579967. doi: 10.3389/fvets.2020.579967. eCollection 2020.

There are several non-steroidal intra-articular therapeutics (NSIATs) available for use by equine practitioners for the treatment of performance-limiting joint-related pathology. Information is limited on perceived clinical efficacy, recommended treatment protocols, and associated complications. Our objective with this cross-sectional survey...

COVID-19 and the Forgotten Organ: Prolonged Changes to the Metabolic Output of the Gut Microbiome.

Gastroenterology

Venzon M, Cadwell K.
PMID: 34800482
Gastroenterology. 2021 Nov 17; doi: 10.1053/j.gastro.2021.11.017. Epub 2021 Nov 17.

No abstract available.

Screening for Pancreatic Ductal Adenocarcinoma: Are We Asking the Impossible?-Response.

Cancer prevention research (Philadelphia, Pa.)

Caldwell KE, Hammill CW.
PMID: 34607878
Cancer Prev Res (Phila). 2021 Oct;14(10):975-976. doi: 10.1158/1940-6207.CAPR-21-0257.

No abstract available.

Performance of the McGill Interactive Pediatric OncoGenetic Guidelines for Identifying Cancer Predisposition Syndromes.

JAMA oncology

Goudie C, Witkowski L, Cullinan N, Reichman L, Schiller I, Tachdjian M, Armstrong L, Blood KA, Brossard J, Brunga L, Cacciotti C, Caswell K, Cellot S, Clark ME, Clinton C, Coltin H, Felton K, Fernandez CV, Fleming AJ, Fuentes-Bolanos N, Gibson P, Grant R, Hammad R, Harrison LW, Irwin MS, Johnston DL, Kane S, Lafay-Cousin L, Lara-Corrales I, Larouche V, Mathews N, Meyn MS, Michaeli O, Perrier R, Pike M, Punnett A, Ramaswamy V, Say J, Somers G, Tabori U, Thibodeau ML, Toupin AK, Tucker KM, van Engelen K, Vairy S, Waespe N, Warby M, Wasserman JD, Whitlock JA, Sinnett D, Jabado N, Nathan PC, Shlien A, Kamihara J, Deyell RJ, Ziegler DS, Nichols KE, Dendukuri N, Malkin D, Villani A, Foulkes WD.
PMID: 34617981
JAMA Oncol. 2021 Dec 01;7(12):1806-1814. doi: 10.1001/jamaoncol.2021.4536.

IMPORTANCE: Prompt recognition of a child with a cancer predisposition syndrome (CPS) has implications for cancer management, surveillance, genetic counseling, and cascade testing of relatives. Diagnosis of CPS requires practitioner expertise, access to genetic testing, and test result interpretation....

Metastasis-Entrained Eosinophils Enhance Lymphocyte-Mediated Antitumor Immunity.

Cancer research

Grisaru-Tal S, Dulberg S, Beck L, Zhang C, Itan M, Hediyeh-Zadeh S, Caldwell J, Rozenberg P, Dolitzky A, Avlas S, Hazut I, Gordon Y, Shani O, Tsuriel S, Gerlic M, Erez N, Jacquelot N, Belz GT, Rothenberg ME, Davis MJ, Yu H, Geiger T, Madi A, Munitz A.
PMID: 34429328
Cancer Res. 2021 Nov 01;81(21):5555-5571. doi: 10.1158/0008-5472.CAN-21-0839. Epub 2021 Aug 24.

The recognition of the immune system as a key component of the tumor microenvironment (TME) led to promising therapeutics. Because such therapies benefit only subsets of patients, understanding the activities of immune cells in the TME is required. Eosinophils...

Showing 397 to 404 of 404 entries