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Showing 13 to 24 of 45 entries
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Modulation of GABAergic transmission in development and neurodevelopmental disorders: investigating physiology and pathology to gain therapeutic perspectives.

Frontiers in cellular neuroscience

Deidda G, Bozarth IF, Cancedda L.
PMID: 24904277
Front Cell Neurosci. 2014 May 22;8:119. doi: 10.3389/fncel.2014.00119. eCollection 2014.

During mammalian ontogenesis, the neurotransmitter GABA is a fundamental regulator of neuronal networks. In neuronal development, GABAergic signaling regulates neural proliferation, migration, differentiation, and neuronal-network wiring. In the adult, GABA orchestrates the activity of different neuronal cell-types largely interconnected,...

High-Resolution X-Ray Tomography: A 3D Exploration Into the Skeletal Architecture in Mouse Models Submitted to Microgravity Constraints.

Frontiers in physiology

Giuliani A, Mazzoni S, Ruggiu A, Canciani B, Cancedda R, Tavella S.
PMID: 29593553
Front Physiol. 2018 Mar 06;9:181. doi: 10.3389/fphys.2018.00181. eCollection 2018.

Bone remodeling process consists in a slow building phase and in faster resorption with the objective to maintain a functional skeleton locomotion to counteract the Earth gravity. Thus, during spaceflights, the skeleton does not act against gravity, with a...

Culture Medium Supplements Derived from Human Platelet and Plasma: Cell Commitment and Proliferation Support.

Frontiers in bioengineering and biotechnology

Muraglia A, Nguyen VT, Nardini M, Mogni M, Coviello D, Dozin B, Strada P, Baldelli I, Formica M, Cancedda R, Mastrogiacomo M.
PMID: 29209609
Front Bioeng Biotechnol. 2017 Nov 20;5:66. doi: 10.3389/fbioe.2017.00066. eCollection 2017.

Present cell culture medium supplements, in most cases based on animal sera, are not fully satisfactory especially for the

Megavoltage Radiotherapy for the Treatment of Degenerative Joint Disease in Dogs: Results of a Preliminary Experience in an Italian Radiotherapy Centre.

Frontiers in veterinary science

Rossi F, Cancedda S, Leone VF, Rohrer Bley C, Laganga P.
PMID: 29692993
Front Vet Sci. 2018 Apr 10;5:74. doi: 10.3389/fvets.2018.00074. eCollection 2018.

The aim of the study was to evaluate the efficacy and toxicity of a low-dose radiotherapy treatment in dogs with osteoarthritis (OA). Inclusion criteria were dogs affected by OA of one or multiple joints, with lameness, previously treated with...

Mice Drawer System: phase c/d development and perspective.

Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology

Cancedda R, Pignataro S, Alberici G, Tenconi C.
PMID: 15002603
J Gravit Physiol. 2002 Jul;9(1):P337-8.

MDS (Mice Drawer System) is the Facility that will support the research on board the International Space Station (ISS). Funded by ASI with Laben as industrial Prime Contractor, MDS will also permit its utilisation for other research programs with...

Liver proteome dataset of .

Data in brief

Ghisaura S, Melis R, Biosa G, Pagnozzi D, Slavski H, Uzzau S, Anedda R, Addis MF.
PMID: 31528672
Data Brief. 2019 Aug 19;26:104419. doi: 10.1016/j.dib.2019.104419. eCollection 2019 Oct.

We report the proteomic dataset of livers from

Human Articular Chondrocytes Regulate Immune Response by Affecting Directly T Cell Proliferation and Indirectly Inhibiting Monocyte Differentiation to Professional Antigen-Presenting Cells.

Frontiers in immunology

Pereira RC, Martinelli D, Cancedda R, Gentili C, Poggi A.
PMID: 27822208
Front Immunol. 2016 Oct 24;7:415. doi: 10.3389/fimmu.2016.00415. eCollection 2016.

Autologous chondrocyte implantation is the current gold standard cell therapy for cartilage lesions. However, in some instances, the heavily compromised health of the patient can either impair or limit the recovery of the autologous chondrocytes and a satisfactory outcome...

Restoring neuronal chloride homeostasis with anti-NKCC1 gene therapy rescues cognitive deficits in a mouse model of Down syndrome.

Molecular therapy : the journal of the American Society of Gene Therapy

Parrini M, Naskar S, Alberti M, Colombi I, Morelli G, Rocchi A, Nanni M, Piccardi F, Charles S, Ronzitti G, Mingozzi F, Contestabile A, Cancedda L.
PMID: 34058387
Mol Ther. 2021 Oct 06;29(10):3072-3092. doi: 10.1016/j.ymthe.2021.05.023. Epub 2021 May 29.

A common feature of diverse brain disorders is the alteration of GABA-mediated inhibition because of aberrant, intracellular chloride homeostasis induced by changes in the expression and/or function of chloride transporters. Notably, pharmacological inhibition of the chloride importer NKCC1 is...

Hierarchy of qualities in global health partnerships: a path towards equity and sustainability.

BMJ global health

Schriger S, Binagwaho A, Keetile M, Kerry V, Mubiligi JM, Ramogola-Masire D, Roland M, Barg FK, Cancedda C.
PMID: 34969686
BMJ Glob Health. 2021 Dec;6(12). doi: 10.1136/bmjgh-2021-007132.

Despite the exponential growth of global health partnerships (GHPs) over the past 20 years, evidence for their effectiveness remains limited. Furthermore, many partnerships are dysfunctional as a result of inequitable partnership benefits, low trust and accountability and poor evaluation...

Hierarchy of qualities in global health partnerships: a path towards equity and sustainability.

BMJ global health

Schriger S, Binagwaho A, Keetile M, Kerry V, Mubiligi JM, Ramogola-Masire D, Roland M, Barg FK, Cancedda C.
PMID: 34969686
BMJ Glob Health. 2021 Dec;6(12). doi: 10.1136/bmjgh-2021-007132.

Despite the exponential growth of global health partnerships (GHPs) over the past 20 years, evidence for their effectiveness remains limited. Furthermore, many partnerships are dysfunctional as a result of inequitable partnership benefits, low trust and accountability and poor evaluation...

Oleosin Cor a 15 is a novel allergen for Italian hazelnut allergic children.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology

Nebbia S, Lamberti C, Cirrincione S, Acquadro A, Abbà S, Ciuffo M, Torello Marinoni D, Manfredi M, Marengo E, Calzedda R, Monti G, Cavallarin L, Giuffrida MG.
PMID: 34146442
Pediatr Allergy Immunol. 2021 Nov;32(8):1743-1755. doi: 10.1111/pai.13579. Epub 2021 Jul 05.

BACKGROUND: Hazelnut allergy, which is characterized by symptoms that range from mild to severe, is one of the most common allergies in children throughout Europe, and an accurate diagnosis of this allergy is therefore essential. However, lipophilic allergens, such...

Tau Biomarkers in Dementia: Positron Emission Tomography Radiopharmaceuticals in Tauopathy Assessment and Future Perspective.

International journal of molecular sciences

Ricci M, Cimini A, Camedda R, Chiaravalloti A, Schillaci O.
PMID: 34884804
Int J Mol Sci. 2021 Nov 30;22(23). doi: 10.3390/ijms222313002.

Abnormal accumulation of Tau protein is closely associated with neurodegeneration and cognitive impairment and it is a biomarker of neurodegeneration in the dementia field, especially in Alzheimer's disease (AD); therefore, it is crucial to be able to assess the...

Showing 13 to 24 of 45 entries