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Showing 25 to 36 of 45 entries
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GABAergic control of neurite outgrowth and remodeling during development and adult neurogenesis: general rules and differences in diverse systems.

Frontiers in cellular neuroscience

Sernagor E, Chabrol F, Bony G, Cancedda L.
PMID: 20428495
Front Cell Neurosci. 2010 Apr 14;4:11. doi: 10.3389/fncel.2010.00011. eCollection 2010.

During development, Gamma-aminobutyric acidergic (GABAergic) neurons mature at early stages, long before excitatory neurons. Conversely, GABA reuptake transporters become operative later than glutamate transporters. GABA is therefore not removed efficiently from the extracellular domain and it can exert significant...

High-Resolution X-Ray Techniques as New Tool to Investigate the 3D Vascularization of Engineered-Bone Tissue.

Frontiers in bioengineering and biotechnology

Bukreeva I, Fratini M, Campi G, Pelliccia D, Spanò R, Tromba G, Brun F, Burghammer M, Grilli M, Cancedda R, Cedola A, Mastrogiacomo M.
PMID: 26442248
Front Bioeng Biotechnol. 2015 Sep 07;3:133. doi: 10.3389/fbioe.2015.00133. eCollection 2015.

The understanding of structure-function relationships in normal and pathologic mammalian tissues is at the basis of a tissue engineering (TE) approach for the development of biological substitutes to restore or improve tissue function. In this framework, it is interesting...

A low-field Nuclear Magnetic Resonance dataset of whole milk during coagulation and syneresis.

Data in brief

Curti E, Pardu A, Del Vigo S, Sanna R, Anedda R.
PMID: 31667283
Data Brief. 2019 Sep 16;26:104520. doi: 10.1016/j.dib.2019.104520. eCollection 2019 Oct.

We report the relaxometric dataset obtained on renneted milk during syneresis by Time-Domain Nuclear Magnetic Resonance spectroscopy (TD-NMR). Data were obtained on cow's milk provided by two different producers in two different lactation seasons (April and October) and on...

Publisher Correction: Cortical-like mini-columns of neuronal cells on zinc oxide nanowire surfaces.

Scientific reports

Onesto V, Villani M, Narducci R, Malara N, Imbrogno A, Allione M, Costa N, Coppedè N, Zappettini A, Cannistraci CV, Cancedda L, Amato F, Di Fabrizio E, Gentile F.
PMID: 32620912
Sci Rep. 2020 Jul 03;10(1):11035. doi: 10.1038/s41598-020-67584-4.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Bayesian Analysis of Three Methods for Diagnosis of Cystic Echinococcosis in Sheep.

Pathogens (Basel, Switzerland)

Bonelli P, Loi F, Cancedda MG, Peruzzu A, Antuofermo E, Pintore E, Piseddu T, Garippa G, Masala G.
PMID: 32992621
Pathogens. 2020 Sep 27;9(10). doi: 10.3390/pathogens9100796.

Diagnosis of cystic echinococcosis (CE) in sheep is essentially based on necropsy findings. Clinical symptoms can be easily overlooked, while the use of immunological tests is still not recommended for an intra vitam diagnosis. This study assessed the performances...

Proteomic dataset of Paracentrotus lividus gonads of different sexes and at different maturation stages.

Data in brief

Ghisaura S, Loi B, Biosa G, Baroli M, Pagnozzi D, Roggio T, Uzzau S, Anedda R, Addis MF.
PMID: 27508229
Data Brief. 2016 Jun 29;8:824-7. doi: 10.1016/j.dib.2016.06.037. eCollection 2016 Sep.

We report the proteomic dataset of gonads from wild Paracentrotus lividus related to the research article entitled "Proteomic changes occurring along gonad maturation in the edible sea urchin Paracentrotus lividus" [1]. Gonads of three individuals per sex in the...

Biomechanical evaluation of cell-loaded and cell-free hydroxyapatite implants for the reconstruction of segmental bone defects.

Journal of materials science. Materials in medicine

Chistolini P, Ruspantini I, Bianco P, Corsi A, Cancedda R, Quarto R.
PMID: 15347943
J Mater Sci Mater Med. 1999 Dec;10(12):739-42. doi: 10.1023/a:1008939524807.

Porous hydroxyapatite (HA) scaffoldings are currently used in tissue engineering for bone reconstruction. When this osteoconductive biomaterial is combined with osteoprogenitor cells, it acquires osteoinductive features which accelerate and improve bone formation in vivo. The aim of our study...

The Regenerative Role of the Fetal and Adult Stem Cell Secretome.

Journal of clinical medicine

Bollini S, Gentili C, Tasso R, Cancedda R.
PMID: 26237150
J Clin Med. 2013 Dec 17;2(4):302-27. doi: 10.3390/jcm2040302.

For a long time, the stem cell regenerative paradigm has been based on the assumption that progenitor cells play a critical role in tissue repair by means of their plasticity and differentiation potential. However, recent works suggest that the...

Platelet Lysate Activates Human Subcutaneous Adipose Tissue Cells by Promoting Cell Proliferation and Their Paracrine Activity Toward Epidermal Keratinocytes.

Frontiers in bioengineering and biotechnology

Romaldini A, Mastrogiacomo M, Cancedda R, Descalzi F.
PMID: 30622945
Front Bioeng Biotechnol. 2018 Dec 21;6:203. doi: 10.3389/fbioe.2018.00203. eCollection 2018.

Skin chronic wounds are non-healing ulcerative defects, which arise in association with a morbidity state, such as diabetes and vascular insufficiency or as the consequence of systemic factors including advanced age. Platelet Rich Plasma, a platelet-rich blood fraction, can...

Pharmacological tools to target NKCC1 in brain disorders.

Trends in pharmacological sciences

Savardi A, Borgogno M, De Vivo M, Cancedda L.
PMID: 34620512
Trends Pharmacol Sci. 2021 Dec;42(12):1009-1034. doi: 10.1016/j.tips.2021.09.005. Epub 2021 Oct 04.

The chloride importer NKCC1 and the chloride exporter KCC2 are key regulators of neuronal chloride concentration. A defective NKCC1/KCC2 expression ratio is associated with several brain disorders. Preclinical/clinical studies have shown that NKCC1 inhibition by the United States FDA-approved...

Cation-coupled chloride cotransporters: chemical insights and disease implications.

Trends in chemistry

Portioli C, Ruiz Munevar MJ, De Vivo M, Cancedda L.
PMID: 34604727
Trends Chem. 2021 Oct;3(10):832-849. doi: 10.1016/j.trechm.2021.05.004.

Cation-coupled chloride cotransporters (CCCs) modulate the transport of sodium and/or potassium cations coupled with chloride anions across the cell membrane. CCCs thus help regulate intracellular ionic concentration and consequent cell volume homeostasis. This has been largely exploited in the...

Discovery of a Small Molecule Drug Candidate for Selective NKCC1 Inhibition in Brain Disorders.

Chem

Savardi A, Borgogno M, Narducci R, La Sala G, Ortega JA, Summa M, Armirotti A, Bertorelli R, Contestabile A, De Vivo M, Cancedda L.
PMID: 32818158
Chem. 2020 Aug 06;6(8):2073-2096. doi: 10.1016/j.chempr.2020.06.017.

Aberrant expression ratio of Cl

Showing 25 to 36 of 45 entries