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Showing 25 to 36 of 43 entries
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COVID-19 heralds a new epistemology of science for the public good.

History and philosophy of the life sciences

Caniglia G, Jaeger C, Schernhammer E, Steiner G, Russo F, Renn J, Schlosser P, Laubichler MD.
PMID: 33864155
Hist Philos Life Sci. 2021 Apr 16;43(2):59. doi: 10.1007/s40656-021-00413-7.

COVID-19 has revealed that science needs to learn how to better deal with the irreducible uncertainty that comes with global systemic risks as well as with the social responsibility of science towards the public good. Further developing the epistemological...

[Considerations on negative P wave in VL].

Folia cardiologica

CANIGGIA A.
PMID: 13060386
Folia Cardiol. 1953 Feb;12(1):13-21.

No abstract available.

Microglia Polarization, Gene-Environment Interactions and Wnt/β-Catenin Signaling: Emerging Roles of Glia-Neuron and Glia-Stem/Neuroprogenitor Crosstalk for Dopaminergic Neurorestoration in Aged Parkinsonian Brain.

Frontiers in aging neuroscience

L'Episcopo F, Tirolo C, Serapide MF, Caniglia S, Testa N, Leggio L, Vivarelli S, Iraci N, Pluchino S, Marchetti B.
PMID: 29483868
Front Aging Neurosci. 2018 Feb 12;10:12. doi: 10.3389/fnagi.2018.00012. eCollection 2018.

Neuroinflammatory processes are recognized key contributory factors in Parkinson's disease (PD) physiopathology. While the causes responsible for the progressive loss of midbrain dopaminergic (mDA) neuronal cell bodies in the subtantia nigra pars compacta are poorly understood, aging, genetics, environmental...

Italian wolves (.

International journal for parasitology. Parasites and wildlife

Poglayen G, Gori F, Morandi B, Galuppi R, Fabbri E, Caniglia R, Milanesi P, Galaverni M, Randi E, Marchesi B, Deplazes P.
PMID: 28180084
Int J Parasitol Parasites Wildl. 2017 Jan 18;6(1):1-7. doi: 10.1016/j.ijppaw.2017.01.001. eCollection 2017 Apr.

After centuries of massive decline, the recovery of the wolf (

Modeling normativity in sustainability: a comparison of the sustainable development goals, the Paris agreement, and the papal encyclical.

Sustainability science

Schmieg G, Meyer E, Schrickel I, Herberg J, Caniglia G, Vilsmaier U, Laubichler M, Hörl E, Lang D.
PMID: 30147791
Sustain Sci. 2018;13(3):785-796. doi: 10.1007/s11625-017-0504-7. Epub 2017 Oct 29.

The idea of sustainability is intrinsically normative. Thus, understanding the role of normativity in sustainability discourses is crucial for further developing sustainability science. In this article, we analyze three important documents that aim to advance sustainability and explore how...

Mycophenolate mofetil and Sirolimus as second or further line treatment in children with chronic refractory Primitive or Secondary Autoimmune Cytopenias: a single centre experience.

British journal of haematology

Miano M, Scalzone M, Perri K, Palmisani E, Caviglia I, Micalizzi C, Svahn J, Calvillo M, Banov L, Terranova P, Lanza T, Dufour C, Fioredda F.
PMID: 26058843
Br J Haematol. 2015 Oct;171(2):247-253. doi: 10.1111/bjh.13533. Epub 2015 Jun 08.

The management of refractory autoimmune cytopenias in childhood is challenging due to the lack of established evidence on escalating treatments. The long-term efficacy of immunosuppressive drugs was evaluated in children with refractory autoimmune cytopenias referred to the Haematology Unit...

Guidelines for the management of bacterial and fungal infections during chemotherapy for pediatric acute leukemia or solid tumors: what is available in 2010?.

Pediatric reports

Castagnola E, Caviglia I, Haupt R.
PMID: 21647280
Pediatr Rep. 2011 Feb 24;3(1):e7. doi: 10.4081/pr.2011.e7.

Febrile episodes and infections represent important complications during antineoplastic chemotherapy for pediatric neoplastic diseases. In the last years many international association published guidelines for the management of these complications in adults, but no document of this type was prepared...

Combining Bayesian genetic clustering and ecological niche modeling: Insights into wolf intraspecific genetic structure.

Ecology and evolution

Milanesi P, Caniglia R, Fabbri E, Puopolo F, Galaverni M, Holderegger R.
PMID: 30519439
Ecol Evol. 2018 Oct 30;8(22):11224-11234. doi: 10.1002/ece3.4594. eCollection 2018 Nov.

The distribution of intraspecific genetic variation and how it relates to environmental factors is of increasing interest to researchers in macroecology and biogeography. Recent studies investigated the relationships between the environment and patterns of intraspecific genetic variation across species...

Ceramide-Induced Lysosomal Biogenesis and Exocytosis in Early-Onset Preeclampsia Promotes Exosomal Release of SMPD1 Causing Endothelial Dysfunction.

Frontiers in cell and developmental biology

Ermini L, Farrell A, Alahari S, Ausman J, Park C, Sallais J, Melland-Smith M, Porter T, Edson M, Nevo O, Litvack M, Post M, Caniggia I.
PMID: 34017832
Front Cell Dev Biol. 2021 May 04;9:652651. doi: 10.3389/fcell.2021.652651. eCollection 2021.

Aberrant ceramide build-up in preeclampsia, a serious disorder of pregnancy, causes exuberant autophagy-mediated trophoblast cell death. The significance of ceramide accumulation for lysosomal biogenesis in preeclampsia is unknown. Here we report that lysosome formation is markedly increased in trophoblast...

Boosting Antioxidant Self-defenses by Grafting Astrocytes Rejuvenates the Aged Microenvironment and Mitigates Nigrostriatal Toxicity in Parkinsonian Brain .

Frontiers in aging neuroscience

Serapide MF, L'Episcopo F, Tirolo C, Testa N, Caniglia S, Giachino C, Marchetti B.
PMID: 32226376
Front Aging Neurosci. 2020 Mar 12;12:24. doi: 10.3389/fnagi.2020.00024. eCollection 2020.

Astrocyte (As) bidirectional dialog with neurons plays a fundamental role in major homeostatic brain functions, particularly providing metabolic support and antioxidant self-defense against reactive oxygen (ROS) and nitrogen species (RNS)

JMJD6 Dysfunction Due to Iron Deficiency in Preeclampsia Disrupts Fibronectin Homeostasis Resulting in Diminished Trophoblast Migration.

Frontiers in cell and developmental biology

Alahari S, Farrell A, Ermini L, Park C, Sallais J, Roberts S, Gillmore T, Litvack M, Post M, Caniggia I.
PMID: 34055782
Front Cell Dev Biol. 2021 May 12;9:652607. doi: 10.3389/fcell.2021.652607. eCollection 2021.

The mechanisms contributing to excessive fibronectin in preeclampsia, a pregnancy-related disorder, remain unknown. Herein, we investigated the role of JMJD6, an O

JMJD6 Dysfunction Due to Iron Deficiency in Preeclampsia Disrupts Fibronectin Homeostasis Resulting in Diminished Trophoblast Migration.

Frontiers in cell and developmental biology

Alahari S, Farrell A, Ermini L, Park C, Sallais J, Roberts S, Gillmore T, Litvack M, Post M, Caniggia I.
PMID: 34055782
Front Cell Dev Biol. 2021 May 12;9:652607. doi: 10.3389/fcell.2021.652607. eCollection 2021.

The mechanisms contributing to excessive fibronectin in preeclampsia, a pregnancy-related disorder, remain unknown. Herein, we investigated the role of JMJD6, an O

Showing 25 to 36 of 43 entries