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Showing 25 to 32 of 32 entries
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The neuroprotective steroid progesterone promotes mitochondrial uncoupling, reduces cytosolic calcium and augments stress resistance in yeast cells.

Microbial cell (Graz, Austria)

Stekovic S, Ruckenstuhl C, Royer P, Winkler-Hermaden C, Carmona-Gutierrez D, Fröhlich KU, Kroemer G, Madeo F.
PMID: 28660203
Microb Cell. 2017 May 31;4(6):191-199. doi: 10.15698/mic2017.06.577.

The steroid hormone progesterone is not only a crucial sex hormone, but also serves as a neurosteroid, thus playing an important role in brain function. Epidemiological data suggest that progesterone improves the recovery of patients after traumatic brain injury....

Guidelines and recommendations on yeast cell death nomenclature.

Microbial cell (Graz, Austria)

Carmona-Gutierrez D, Bauer MA, Zimmermann A, Aguilera A, Austriaco N, Ayscough K, Balzan R, Bar-Nun S, Barrientos A, Belenky P, Blondel M, Braun RJ, Breitenbach M, Burhans WC, Büttner S, Cavalieri D, Chang M, Cooper KF, Côrte-Real M, Costa V, Cullin C, Dawes I, Dengjel J, Dickman MB, Eisenberg T, Fahrenkrog B, Fasel N, Fröhlich KU, Gargouri A, Giannattasio S, Goffrini P, Gourlay CW, Grant CM, Greenwood MT, Guaragnella N, Heger T, Heinisch J, Herker E, Herrmann JM, Hofer S, Jiménez-Ruiz A, Jungwirth H, Kainz K, Kontoyiannis DP, Ludovico P, Manon S, Martegani E, Mazzoni C, Megeney LA, Meisinger C, Nielsen J, Nyström T, Osiewacz HD, Outeiro TF, Park HO, Pendl T, Petranovic D, Picot S, Polčic P, Powers T, Ramsdale M, Rinnerthaler M, Rockenfeller P, Ruckenstuhl C, Schaffrath R, Segovia M, Severin FF, Sharon A, Sigrist SJ, Sommer-Ruck C, Sousa MJ, Thevelein JM, Thevissen K, Titorenko V, Toledano MB, Tuite M, Vögtle FN, Westermann B, Winderickx J, Wissing S, Wölfl S, Zhang ZJ, Zhao RY, Zhou B, Galluzzi L, Kroemer G, Madeo F.
PMID: 29354647
Microb Cell. 2018 Jan 01;5(1):4-31. doi: 10.15698/mic2018.01.607.

Elucidating the biology of yeast in its full complexity has major implications for science, medicine and industry. One of the most critical processes determining yeast life and physiology is cel-lular demise. However, the investigation of yeast cell death is...

Murals meet microbes: at the crossroads of microbiology and cultural heritage.

Microbial cell (Graz, Austria)

Bauer MA, Kainz K, Ruckenstuhl C, Madeo F, Carmona-Gutierrez D.
PMID: 34909431
Microb Cell. 2021 Dec 06;8(12):276-279. doi: 10.15698/mic2021.12.765. eCollection 2021 Dec 06.

Our cultural heritage consists of manifold cultural expressions and represents a defining feature of our societies that needs to be further inherited to future generations. Even though humankind always fought a daily struggle for survival, at the same time,...

Digesting the crisis: autophagy and coronaviruses.

Microbial cell (Graz, Austria)

Carmona-Gutierrez D, Bauer MA, Zimmermann A, Kainz K, Hofer SJ, Kroemer G, Madeo F.
PMID: 32391393
Microb Cell. 2020 May 04;7(5):119-128. doi: 10.15698/mic2020.05.715.

Autophagy is a catabolic pathway with multifaceted roles in cellular homeostasis. This process is also involved in the antiviral response at multiple levels, including the direct elimination of intruding viruses (virophagy), the presentation of viral antigens, the fitness of...

The ups and downs of caloric restriction and fasting: from molecular effects to clinical application.

EMBO molecular medicine

Hofer SJ, Carmona-Gutierrez D, Mueller MI, Madeo F.
PMID: 34779138
EMBO Mol Med. 2022 Jan 11;14(1):e14418. doi: 10.15252/emmm.202114418. Epub 2021 Nov 15.

Age-associated diseases are rising to pandemic proportions, exposing the need for efficient and low-cost methods to tackle these maladies at symptomatic, behavioral, metabolic, and physiological levels. While nutrition and health are closely intertwined, our limited understanding of how diet...

Ethanolamine: A novel anti-aging agent.

Molecular & cellular oncology

Rockenfeller P, Carmona-Gutierrez D, Pietrocola F, Kroemer G, Madeo F.
PMID: 27308532
Mol Cell Oncol. 2015 Mar 19;3(1):e1019023. doi: 10.1080/23723556.2015.1019023. eCollection 2016 Jan.

Ethanolamine (Etn) is a naturally occurring aminoalcohol necessary for synthesis of the phospholipid phosphatidylethanolamine (PE), a major component of biological membranes. We recently reported that Etn treatment increases cellular PE levels, thereby inducing cytoprotective autophagy and protecting against aging...

When death was young: an ancestral apoptotic network in bacteria.

Molecular cell

Carmona-Gutierrez D, Kroemer G, Madeo F.
PMID: 22681882
Mol Cell. 2012 Jun 08;46(5):552-4. doi: 10.1016/j.molcel.2012.05.032.

In this issue of Molecular Cell, Dwyer et al. (2012) characterize a RecA-dependent and ClpXP-regulated pathway that controls the acquisition of several apoptotic markers upon bactericidal treatment of prokaryotes, placing the hypothetical origin of apoptosis further downstream in evolution.

The ups and downs of caloric restriction and fasting: from molecular effects to clinical application.

EMBO molecular medicine

Hofer SJ, Carmona-Gutierrez D, Mueller MI, Madeo F.
PMID: 34779138
EMBO Mol Med. 2022 Jan 11;14(1):e14418. doi: 10.15252/emmm.202114418. Epub 2021 Nov 15.

Age-associated diseases are rising to pandemic proportions, exposing the need for efficient and low-cost methods to tackle these maladies at symptomatic, behavioral, metabolic, and physiological levels. While nutrition and health are closely intertwined, our limited understanding of how diet...

Showing 25 to 32 of 32 entries