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Showing 193 to 199 of 199 entries
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Strategies to sensitize cancer cells to immunotherapy.

Human vaccines & immunotherapeutics

George A, Sahin I, Carneiro BA, Dizon DS, Safran HP, El-Deiry WS.
PMID: 34019474
Hum Vaccin Immunother. 2021 Aug 03;17(8):2595-2601. doi: 10.1080/21645515.2021.1891817. Epub 2021 May 21.

Recent years have seen the emergence of immunotherapy as a promising modality for treating a variety of cancers. However, the initial data have led to the ultimate reality that such a treatment does not work effectively in all cancers,...

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George A, Sahin I, Carneiro BA, et al. Strategies to sensitize cancer cells to immunotherapy. Hum Vaccin Immunother. 2021;17(8):2595-2601doi: 10.1080/21645515.2021.1891817.
George, A., Sahin, I., Carneiro, B. A., Dizon, D. S., Safran, H. P., & El-Deiry, W. S. (2021). Strategies to sensitize cancer cells to immunotherapy. Human vaccines & immunotherapeutics, 17(8), 2595-2601. https://doi.org/10.1080/21645515.2021.1891817
George, Andrew, et al. "Strategies to sensitize cancer cells to immunotherapy." Human vaccines & immunotherapeutics vol. 17,8 (2021): 2595-2601. doi: https://doi.org/10.1080/21645515.2021.1891817
George A, Sahin I, Carneiro BA, Dizon DS, Safran HP, El-Deiry WS. Strategies to sensitize cancer cells to immunotherapy. Hum Vaccin Immunother. 2021 Aug 03;17(8):2595-2601. doi: 10.1080/21645515.2021.1891817. Epub 2021 May 21. PMID: 34019474; PMCID: PMC8475577.
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Advances in microalgal cell wall polysaccharides: a review focused on structure, production, and biological application.

Critical reviews in biotechnology

Colusse GA, Carneiro J, Duarte MER, Carvalho JC, Noseda MD.
PMID: 34320897
Crit Rev Biotechnol. 2021 Jul 28;1-16. doi: 10.1080/07388551.2021.1941750. Epub 2021 Jul 28.

Microalgae have been shown to be useful in several biotechnological fields due to their feasible cultivation and high-value biomolecules production. Several substances of interest produced by microalgae, such as: proteins, lipids, and natural colorants, have already been explored. Based...

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Colusse GA, Carneiro J, Duarte MER, et al. Advances in microalgal cell wall polysaccharides: a review focused on structure, production, and biological application. Crit Rev Biotechnol. 2021;1-16doi: 10.1080/07388551.2021.1941750.
Colusse, G. A., Carneiro, J., Duarte, M. E. R., Carvalho, J. C., & Noseda, M. D. (2021). Advances in microalgal cell wall polysaccharides: a review focused on structure, production, and biological application. Critical reviews in biotechnology, 1-16. https://doi.org/10.1080/07388551.2021.1941750
Colusse, Guilherme Augusto, et al. "Advances in microalgal cell wall polysaccharides: a review focused on structure, production, and biological application." Critical reviews in biotechnology vol. (2021): 1-16. doi: https://doi.org/10.1080/07388551.2021.1941750
Colusse GA, Carneiro J, Duarte MER, Carvalho JC, Noseda MD. Advances in microalgal cell wall polysaccharides: a review focused on structure, production, and biological application. Crit Rev Biotechnol. 2021 Jul 28;1-16. doi: 10.1080/07388551.2021.1941750. Epub 2021 Jul 28. PMID: 34320897.
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The Role of Magnetic Resonance in the Diagnosis of Chronic Exertional Compartment Syndrome.

Revista brasileira de ortopedia

Nico MAC, Carneiro BC, Zorzenoni FO, Ormond Filho AG, Guimarães JB.
PMID: 33364643
Rev Bras Ortop (Sao Paulo). 2020 Dec;55(6):673-680. doi: 10.1055/s-0040-1702961. Epub 2020 Apr 02.

Chronic compartment syndrome is a common and often underdiagnosed exercise-induced condition, accounting on average for a quarter of cases of chronic exertional pain in the leg, second only to the fracture/tibial stress syndrome spectrum. It traditionally occurs in young...

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Nico MAC, Carneiro BC, Zorzenoni FO, et al. The Role of Magnetic Resonance in the Diagnosis of Chronic Exertional Compartment Syndrome. Rev Bras Ortop (Sao Paulo). 2020;55(6):673-680doi: 10.1055/s-0040-1702961.
Nico, M. A. C., Carneiro, B. C., Zorzenoni, F. O., Ormond Filho, A. G., & Guimarães, J. B. (2020). The Role of Magnetic Resonance in the Diagnosis of Chronic Exertional Compartment Syndrome. Revista brasileira de ortopedia, 55(6), 673-680. https://doi.org/10.1055/s-0040-1702961
Nico, Marcelo Astolfi Caetano, et al. "The Role of Magnetic Resonance in the Diagnosis of Chronic Exertional Compartment Syndrome." Revista brasileira de ortopedia vol. 55,6 (2020): 673-680. doi: https://doi.org/10.1055/s-0040-1702961
Nico MAC, Carneiro BC, Zorzenoni FO, Ormond Filho AG, Guimarães JB. The Role of Magnetic Resonance in the Diagnosis of Chronic Exertional Compartment Syndrome. Rev Bras Ortop (Sao Paulo). 2020 Dec;55(6):673-680. doi: 10.1055/s-0040-1702961. Epub 2020 Apr 02. PMID: 33364643; PMCID: PMC7748934.
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Combination of ONC201 and TLY012 induces selective, synergistic apoptosis in vitro and significantly delays PDAC xenograft growth in vivo.

Cancer biology & therapy

Jhaveri AV, Zhou L, Ralff MD, Lee YS, Navaraj A, Carneiro BA, Safran H, Prabhu VV, Ross EA, Lee S, El-Deiry WS.
PMID: 34856854
Cancer Biol Ther. 2021 Dec 02;1-12. doi: 10.1080/15384047.2021.1976567. Epub 2021 Dec 02.

The five-year survival rate for pancreatic ductal adenocarcinoma (PDAC) has remained a dismal 9% for approximately 40 years with an urgent need for novel therapeutic interventions. ONC201 is the founding member of the imipridone class, comprised of orally bioavailable...

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Jhaveri AV, Zhou L, Ralff MD, et al. Combination of ONC201 and TLY012 induces selective, synergistic apoptosis in vitro and significantly delays PDAC xenograft growth in vivo. Cancer Biol Ther. 2021;1-12doi: 10.1080/15384047.2021.1976567.
Jhaveri, A. V., Zhou, L., Ralff, M. D., Lee, Y. S., Navaraj, A., Carneiro, B. A., Safran, H., Prabhu, V. V., Ross, E. A., Lee, S., & El-Deiry, W. S. (2021). Combination of ONC201 and TLY012 induces selective, synergistic apoptosis in vitro and significantly delays PDAC xenograft growth in vivo. Cancer biology & therapy, 1-12. https://doi.org/10.1080/15384047.2021.1976567
Jhaveri, Aakash V, et al. "Combination of ONC201 and TLY012 induces selective, synergistic apoptosis in vitro and significantly delays PDAC xenograft growth in vivo." Cancer biology & therapy vol. (2021): 1-12. doi: https://doi.org/10.1080/15384047.2021.1976567
Jhaveri AV, Zhou L, Ralff MD, Lee YS, Navaraj A, Carneiro BA, Safran H, Prabhu VV, Ross EA, Lee S, El-Deiry WS. Combination of ONC201 and TLY012 induces selective, synergistic apoptosis in vitro and significantly delays PDAC xenograft growth in vivo. Cancer Biol Ther. 2021 Dec 02;1-12. doi: 10.1080/15384047.2021.1976567. Epub 2021 Dec 02. PMID: 34856854.
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Association of Skeletal Muscle and Cardiovascular Risk Factors in Patients with Lower Extremity Arterial Disease.

Annals of vascular surgery

Ferreira J, Carneiro AL, Vila I, Cunha C, Silva CR, Longatto-Filho A, Mesquita A, Cotter J, Mansilha A, Correia-Neves M, Cunha P.
PMID: 34688875
Ann Vasc Surg. 2021 Oct 21; doi: 10.1016/j.avsg.2021.08.037. Epub 2021 Oct 21.

BACKGROUND: Sarcopenia is defined as low muscle mass, with low muscle strength or low physical performance. The skeletal muscle mass (or density) and strength are inversely associated with cardiovascular risk factors. We aim to determine the relationship between skeletal...

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Ferreira J, Carneiro AL, Vila I, et al. Association of Skeletal Muscle and Cardiovascular Risk Factors in Patients with Lower Extremity Arterial Disease. Ann Vasc Surg. 2021;doi: 10.1016/j.avsg.2021.08.037.
Ferreira, J., Carneiro, A. L., Vila, I., Cunha, C., Silva, C. R., Longatto-Filho, A., Mesquita, A., Cotter, J., Mansilha, A., Correia-Neves, M., & Cunha, P. (2021). Association of Skeletal Muscle and Cardiovascular Risk Factors in Patients with Lower Extremity Arterial Disease. Annals of vascular surgery, . https://doi.org/10.1016/j.avsg.2021.08.037
Ferreira, Joana, et al. "Association of Skeletal Muscle and Cardiovascular Risk Factors in Patients with Lower Extremity Arterial Disease." Annals of vascular surgery vol. (2021). doi: https://doi.org/10.1016/j.avsg.2021.08.037
Ferreira J, Carneiro AL, Vila I, Cunha C, Silva CR, Longatto-Filho A, Mesquita A, Cotter J, Mansilha A, Correia-Neves M, Cunha P. Association of Skeletal Muscle and Cardiovascular Risk Factors in Patients with Lower Extremity Arterial Disease. Ann Vasc Surg. 2021 Oct 21; doi: 10.1016/j.avsg.2021.08.037. Epub 2021 Oct 21. PMID: 34688875.
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Assessing the effects of PMM2 variants on protein stability.

Molecular genetics and metabolism

Quelhas D, Carneiro J, Lopes-Marques M, Jaeken J, Martins E, Rocha JF, Teixeira Carla SS, Ferreira CR, Sousa SF, Azevedo L.
PMID: 34863624
Mol Genet Metab. 2021 Dec;134(4):344-352. doi: 10.1016/j.ymgme.2021.11.002. Epub 2021 Nov 08.

Phosphomannomutase 2 deficiency, PMM2-CDG, is the most frequent disorder of protein N-glycosylation. It is an autosomal recessive disease with a broad clinical and biochemical phenotype. Trying to predict the impact of novel variants is often a challenge due to...

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Quelhas D, Carneiro J, Lopes-Marques M, et al. Assessing the effects of PMM2 variants on protein stability. Mol Genet Metab. 2021;134(4):344-352doi: 10.1016/j.ymgme.2021.11.002.
Quelhas, D., Carneiro, J., Lopes-Marques, M., Jaeken, J., Martins, E., Rocha, J. F., Teixeira Carla, S. S., Ferreira, C. R., Sousa, S. F., & Azevedo, L. (2021). Assessing the effects of PMM2 variants on protein stability. Molecular genetics and metabolism, 134(4), 344-352. https://doi.org/10.1016/j.ymgme.2021.11.002
Quelhas, D, et al. "Assessing the effects of PMM2 variants on protein stability." Molecular genetics and metabolism vol. 134,4 (2021): 344-352. doi: https://doi.org/10.1016/j.ymgme.2021.11.002
Quelhas D, Carneiro J, Lopes-Marques M, Jaeken J, Martins E, Rocha JF, Teixeira Carla SS, Ferreira CR, Sousa SF, Azevedo L. Assessing the effects of PMM2 variants on protein stability. Mol Genet Metab. 2021 Dec;134(4):344-352. doi: 10.1016/j.ymgme.2021.11.002. Epub 2021 Nov 08. PMID: 34863624.
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Individual variation in susceptibility or exposure to SARS-CoV-2 lowers the herd immunity threshold.

medRxiv : the preprint server for health sciences

Gomes MGM, Aguas R, King JG, Langwig KE, Souto-Maior C, Carneiro J, Penha-Gonçalves C, Gonçalves G, Ferreira MU.
PMID: 32511451
medRxiv. 2021 Aug 01; doi: 10.1101/2020.04.27.20081893.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began to spread in late 2019, gradually depleting susceptible populations and causing the incidence of new infections to decline over time. Variation in individual susceptibility or exposure to infection exacerbated this effect....

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Gomes MGM, Aguas R, King JG, et al. Individual variation in susceptibility or exposure to SARS-CoV-2 lowers the herd immunity threshold. medRxiv. 2021;doi: 10.1101/2020.04.27.20081893.
Gomes, M. G. M., Aguas, R., King, J. G., Langwig, K. E., Souto-Maior, C., Carneiro, J., Penha-Gonçalves, C., Gonçalves, G., & Ferreira, M. U. (2021). Individual variation in susceptibility or exposure to SARS-CoV-2 lowers the herd immunity threshold. medRxiv : the preprint server for health sciences, . https://doi.org/10.1101/2020.04.27.20081893
Gomes, M Gabriela M, et al. "Individual variation in susceptibility or exposure to SARS-CoV-2 lowers the herd immunity threshold." medRxiv : the preprint server for health sciences vol. (2021). doi: https://doi.org/10.1101/2020.04.27.20081893
Gomes MGM, Aguas R, King JG, Langwig KE, Souto-Maior C, Carneiro J, Penha-Gonçalves C, Gonçalves G, Ferreira MU. Individual variation in susceptibility or exposure to SARS-CoV-2 lowers the herd immunity threshold. medRxiv. 2021 Aug 01; doi: 10.1101/2020.04.27.20081893. PMID: 32511451; PMCID: PMC7239079.
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Showing 193 to 199 of 199 entries