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Showing 565 to 571 of 571 entries
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Sedation and analgesia needs in methamphetamine intoxicated patients: much ado about nothing.

Injury

Chiang E, Case J, Cook MR, Schreiber M, Sorenson C, Barton C.
PMID: 34802698
Injury. 2021 Nov 01; doi: 10.1016/j.injury.2021.10.021. Epub 2021 Nov 01.

BACKGROUND: Methamphetamine (M) is a widely used, powerful sympathomimetic drug that produces significant CNS stimulation. Its use is associated with psychiatric disorders, abnormal brain chemistry, and cardiovascular disease. Pre-hospital M use is associated with increased intubation, intensive care unit...

Practical Guide for Interpreting and Reporting Cardiac PET Measurements of Myocardial Blood Flow: An Information Statement from the American Society of Nuclear Cardiology, and the Society of Nuclear Medicine and Molecular Imaging.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Bateman TM, Heller GV, Beanlands R, Calnon DA, Case J, deKemp R, DePuey EG, Di Carli M, Guler EC, Murthy VL, Rosenblatt J, Sher R, Slomka P, Ruddy TD.
PMID: 33789935
J Nucl Med. 2021 Nov;62(11):1599-1615. doi: 10.2967/jnumed.121.261989. Epub 2021 Mar 31.

No abstract available.

The Role of Real-World Evidence in FDA-Approved New Drug and Biologics License Applications.

Clinical pharmacology and therapeutics

Purpura CA, Garry EM, Honig N, Case A, Rassen JA.
PMID: 34726771
Clin Pharmacol Ther. 2022 Jan;111(1):135-144. doi: 10.1002/cpt.2474. Epub 2021 Nov 22.

The US Food and Drug Administration (FDA) is open to accepting real-world evidence (RWE) to support its assessment of medical products. However, RWE stakeholders lack a shared understanding of FDA's evidentiary expectations for the use of RWE in applications...

Vape-Associated Pulmonary Injury (VAPI) Presenting With a "Miliary" Pattern on Imaging.

Cureus

Threadcraft MA, Case R.
PMID: 33754108
Cureus. 2021 Feb 16;13(2):e13385. doi: 10.7759/cureus.13385.

Electronic (E)-cigarette use or vaping is associated with pulmonary injury. Users can present with wide-ranging symptoms, varying degrees of pulmonary injury, and respiratory distress. Lung injury secondary to vaping is associated with a variety of patterns on pulmonary imaging....

The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants.

Cell host & microbe

Liu C, Zhou D, Nutalai R, Duyvesteyn HME, Tuekprakhon A, Ginn HM, Dejnirattisai W, Supasa P, Mentzer AJ, Wang B, Case JB, Zhao Y, Skelly DT, Chen RE, Johnson SA, Ritter TG, Mason C, Malik T, Temperton N, Paterson NG, Williams MA, Hall DR, Clare DK, Howe A, Goulder PJR, Fry EE, Diamond MS, Mongkolsapaya J, Ren J, Stuart DI, Screaton GR.
PMID: 34921776
Cell Host Microbe. 2022 Jan 12;30(1):53-68.e12. doi: 10.1016/j.chom.2021.11.013. Epub 2021 Nov 27.

Alpha-B.1.1.7, Beta-B.1.351, Gamma-P.1, and Delta-B.1.617.2 variants of SARS-CoV-2 express multiple mutations in the spike protein (S). These may alter the antigenic structure of S, causing escape from natural or vaccine-induced immunity. Beta is particularly difficult to neutralize using serum...

UNOS/OPTN Data-guided Assessment of Focal Segmental Glomerulosclerosis After Kidney Transplantation and Evaluation of Immunosuppressive Protocols in a Steroid-free Center.

Transplantation direct

Kurian SM, Spierling Bagsic SR, Case J, Barrick BL, Schaffer R, Rice JC, Marsh CL.
PMID: 34386576
Transplant Direct. 2021 Aug 05;7(9):e738. doi: 10.1097/TXD.0000000000001196. eCollection 2021 Sep.

BACKGROUND: Focal segmental glomerulosclerosis (FSGS) is a common recurrent glomerulopathy associated with graft loss and patient survival after kidney transplantation (KT). However, its natural history, clinical predictors, and treatment response are still poorly understood. Steroid withdrawal regimens in KT...

Medical Schools' Willingness to Accommodate Medical Students with Sensory and Physical Disabilities: Ethical Foundations of a Functional Challenge to "Organic" Technical Standards.

McKee M, Case B, Fausone M, Zazove P, Ouellette A, Fetters MD.
UIID-AD: 4247
2016;993-1002. doi: 10.1001/journalofethics.2016.18.10.medu1-1610.

Students with sensory and physical disabilities are underrepresented in medical schools despite the availability of assistive technologies and accommodations. Unfortunately, many medical schools have adopted restrictive "organic" technical standards based on deficits rather than on the ability to do...

Showing 565 to 571 of 571 entries