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Showing 277 to 283 of 283 entries
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Effectiveness of Systematic Echocardiographic Screening for Rheumatic Heart Disease in Nepalese Schoolchildren: A Cluster Randomized Clinical Trial.

JAMA cardiology

Karki P, Uranw S, Bastola S, Mahato R, Shrestha NR, Sherpa K, Dhungana S, Odutayo A, Gurung K, Pandey N, Agrawal K, Shah P, Rothenbühler M, Jüni P, Pilgrim T.
PMID: 33471029
JAMA Cardiol. 2021 Apr 01;6(4):420-426. doi: 10.1001/jamacardio.2020.7050.

IMPORTANCE: Echocardiographic screening allows for early detection of subclinical stages of rheumatic heart disease among children in endemic regions.OBJECTIVE: To investigate the effectiveness of systematic echocardiographic screening in combination with secondary antibiotic prophylaxis on the prevalence of rheumatic heart...

Improvement preclinical and clinical skills for dental preparations using assisted training software.

European journal of dental education : official journal of the Association for Dental Education in Europe

Jorquera G, Sánchez JP, Sampaio CS, Atria P, Fernández E.
PMID: 33471391
Eur J Dent Educ. 2021 Nov;25(4):856-863. doi: 10.1111/eje.12665. Epub 2021 Feb 03.

INTRODUCTION: Digital workflow is currently available for different fields of dentistry. Additionally, to clinical use, digital technology is focused on the education and training of students. The objective of this study was to show the potential benefit of the...

Impact of Fluoroalkylation on the n-Type Charge Transport of Two Naphthodithiophene Diimide Derivatives.

Molecules (Basel, Switzerland)

Ricci G, Canola S, Dai Y, Fazzi D, Negri F.
PMID: 34299394
Molecules. 2021 Jul 06;26(14). doi: 10.3390/molecules26144119.

In this work, we investigate two recently synthesized naphthodithiophene diimide (NDTI) derivatives featuring promising n-type charge transport properties. We analyze the charge transport pathways and model charge mobility with the non-adiabatic hopping mechanism using the Marcus-Levich-Jortner rate constant formulation,...

Transcriptional characterization of the glial response due to chronic neural implantation of flexible microprobes.

Biomaterials

Joseph K, Kirsch M, Johnston M, Münkel C, Stieglitz T, Haas CA, Hofmann UG.
PMID: 34736153
Biomaterials. 2021 Dec;279:121230. doi: 10.1016/j.biomaterials.2021.121230. Epub 2021 Oct 29.

Long term implantation of (micro-)probes into neural tissue causes unique and disruptive responses. In this study, we investigate the transcriptional trajectory of glial cells responding to chronic implantation of 380 μm flexible micro-probes for up to 18 weeks. Transcriptomic...

Sensitive and specific serodiagnosis of tegumentary leishmaniasis using a new chimeric protein based on specific B-cell epitopes of Leishmania antigenic proteins.

Microbial pathogenesis

Galvani NC, Machado AS, Lage DP, Martins VT, de Oliveira D, Freitas CS, Vale DL, Fernandes BB, Oliveira-da-Silva JA, Reis TAR, Santos TTO, Ramos FF, Bandeira RS, Ludolf F, Tavares GSV, Guimarães NS, Tupinambás U, Chávez-Fumagalli MA, Humbert MV, Gonçalves DU, Christodoulides M, Machado-de-Ávila RA, Coelho EAF.
PMID: 34883228
Microb Pathog. 2021 Dec 06;162:105341. doi: 10.1016/j.micpath.2021.105341. Epub 2021 Dec 06.

Serological tests used for the diagnosis of tegumentary leishmaniasis (TL) presents problems, mainly related to their variable sensitivity and/or specificity, which can be caused by low levels of antileishmanial antibodies or by presence of cross-reactive diseases, respectively. In this...

Disease Phenotypes and Mechanisms of iPSC-Derived Cardiomyocytes From Brugada Syndrome Patients With a Loss-of-Function SCN5A Mutation.

Frontiers in cell and developmental biology

Li W, Stauske M, Luo X, Wagner S, Vollrath M, Mehnert CS, Schubert M, Cyganek L, Chen S, Hasheminasab SM, Wulf G, El-Armouche A, Maier LS, Hasenfuss G, Guan K.
PMID: 33195263
Front Cell Dev Biol. 2020 Oct 22;8:592893. doi: 10.3389/fcell.2020.592893. eCollection 2020.

Brugada syndrome (BrS) is one of the major causes of sudden cardiac death in young people, while the underlying mechanisms are not completely understood. Here, we investigated the pathophysiological phenotypes and mechanisms using induced pluripotent stem cell (iPSC)-derived cardiomyocytes...

Sensitive and specific serodiagnosis of tegumentary leishmaniasis using a new chimeric protein based on specific B-cell epitopes of Leishmania antigenic proteins.

Microbial pathogenesis

Galvani NC, Machado AS, Lage DP, Martins VT, de Oliveira D, Freitas CS, Vale DL, Fernandes BB, Oliveira-da-Silva JA, Reis TAR, Santos TTO, Ramos FF, Bandeira RS, Ludolf F, Tavares GSV, Guimarães NS, Tupinambás U, Chávez-Fumagalli MA, Humbert MV, Gonçalves DU, Christodoulides M, Machado-de-Ávila RA, Coelho EAF.
PMID: 34883228
Microb Pathog. 2021 Dec 06;162:105341. doi: 10.1016/j.micpath.2021.105341. Epub 2021 Dec 06.

Serological tests used for the diagnosis of tegumentary leishmaniasis (TL) presents problems, mainly related to their variable sensitivity and/or specificity, which can be caused by low levels of antileishmanial antibodies or by presence of cross-reactive diseases, respectively. In this...

Showing 277 to 283 of 283 entries