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Showing 25 to 36 of 224 entries
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Interest to consider re-challenging by cetuximab and platinum containing regimen in recurrent Head and Neck Cancer.

Oncotarget

Borel C, Regnier-Gavier O, Carinato H, Guihard S, Antoni D, Demarchi M, Sirlin F, Exinger D, Petit-Jean E, Thiery A, Bronner G, Schultz P, Flesch H, Frasie V, Prébay D, Petit T, Jung AC, Burgy M, Coliat P.
PMID: 30680071
Oncotarget. 2018 Dec 25;9(101):37581-37588. doi: 10.18632/oncotarget.26506. eCollection 2018 Dec 25.

BACKGROUND: The EXTREME protocol is the standard of care for recurrent or metastatic head and neck squamous-cell carcinoma (R/M HNSCC) in first line. Beyond the first-line except immunotherapy, poor efficacy was reported by second-line chemotherapy. Re-challenge strategies based on...

Configuration Space Analysis of the Specific Rotation of Helicenes.

The journal of physical chemistry. A

Aharon T, Caricato M.
PMID: 31042386
J Phys Chem A. 2019 May 23;123(20):4406-4418. doi: 10.1021/acs.jpca.9b01823. Epub 2019 May 10.

In this work, we present an analysis of a series of helicene molecules to determine the driving forces for their large specific rotation, [α]

Towards precision medicine: The application of omics technologies in asthma management.

F1000Research

Scelfo C, Galeone C, Bertolini F, Caminati M, Ruggiero P, Facciolongo N, Menzella F.
PMID: 29904594
F1000Res. 2018 Apr 04;7:423. doi: 10.12688/f1000research.14309.1. eCollection 2018.

Asthma is a chronic obstructive respiratory disease characterised by bronchial inflammation. Its biological and clinical features have been widely explored and a number of pharmacological treatments are currently available. Currently several aspects of asthma pathophysiological background remain unclear, and...

Origin invariant full optical rotation tensor in the length dipole gauge without London atomic orbitals.

The Journal of chemical physics

Caricato M, Balduf T.
PMID: 34266245
J Chem Phys. 2021 Jul 14;155(2):024118. doi: 10.1063/5.0053450.

We present an origin-invariant approach to compute the full optical rotation tensor (Buckingham/Dunn tensor) in the length dipole gauge without recourse to London atomic orbitals, called LG(OI). The LG(OI) approach is simpler and less computationally demanding than the more...

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EJNMMI research

Sollini M, Bartoli F, Cavinato L, Ieva F, Ragni A, Marciano A, Zanca R, Galli L, Paiar F, Pasqualetti F, Erba PA.
PMID: 34837532
EJNMMI Res. 2021 Nov 27;11(1):119. doi: 10.1186/s13550-021-00858-8.

BACKGROUND: The role of image-derived biomarkers in recurrent oligometastatic Prostate Cancer (PCa) is unexplored. This paper aimed to evaluate [METHODS: PCa patients eligible for [RESULTS: [CONCLUSIONS: We found a comparable heterogeneity between patients with up to five lesions and...

Scarless Total Breast Reconstruction with a Fat-augmented Latissimus Dorsi Flap.

Plastic and reconstructive surgery. Global open

Maitani K, Tomita K, Taminato M, Kubo T.
PMID: 34703717
Plast Reconstr Surg Glob Open. 2021 Oct 22;9(10):e3887. doi: 10.1097/GOX.0000000000003887. eCollection 2021 Oct.

Total breast reconstruction with a fat-augmented latissimus dorsi flap (F-LDF) is a breakthrough approach that surmounts the shortcomings of the latissimus dorsi flap (LDF), such as volume insufficiency. Unlike the abdominal flap, the LDF can be harvested as a...

Human Cytomegalovirus Replication and Infection-Induced Syncytia Formation in Labial, Foreskin, and Fetal Lung Fibroblasts.

Viruses

Aguiar A, Galinato M, Bradley Silva M, Toth B, McVoy MA, Hertel L.
PMID: 34960624
Viruses. 2021 Nov 24;13(12). doi: 10.3390/v13122355.

Only a handful of cell types, including fibroblasts, epithelial, and endothelial cells, can support human cytomegalovirus (CMV) replication in vitro, in striking contrast to the situation in vivo. While the susceptibility of epithelial and endothelial cells to CMV infection...

Benchmark Study of Ground-State Raman Spectra in Conjugated Molecules.

Journal of chemical theory and computation

Barclay MS, Elles CG, Caricato M.
PMID: 31790252
J Chem Theory Comput. 2020 Jan 14;16(1):612-620. doi: 10.1021/acs.jctc.9b00960. Epub 2019 Dec 16.

In this work, we compare calculated and experimental off-resonance Raman spectra for a series of substituted benzene and thiophene derivatives in the ground state. We benchmark a variety of approximate density functionals following the "Jacob's Ladder" hierarchy of chemical...

Radiographic evaluation of humeral head reconstruction with stemmed and stemless spherical implants compared with stemless elliptical head implants.

JSES international

Cavinatto L, Khatib O, Martusiewicz A, Koueiter DM, Wiater BP, Wiater JM.
PMID: 34505101
JSES Int. 2021 May 23;5(5):889-893. doi: 10.1016/j.jseint.2021.04.015. eCollection 2021 Sep.

BACKGROUND: The purpose of this study was to compare the accuracy of anatomic reconstruction of three different humeral head designs after anatomic total shoulder arthroplasty.METHODS: Postoperative radiographs of 117 patients who underwent anatomic total shoulder arthroplasty with three different...

Prevalence of severe asthma according to the drug regulatory agency perspective: An Italian experience.

The World Allergy Organization journal

Vianello A, Caminati M, Andretta M, Menti AM, Tognella S, Senna G, Degli Esposti L.
PMID: 31193146
World Allergy Organ J. 2019 May 10;12(4):100032. doi: 10.1016/j.waojou.2019.100032. eCollection 2019.

No abstract available.

Identification of remodeled collagen fibers in tumor stroma by FTIR Micro-spectroscopy: A new approach to recognize the colon carcinoma.

Biochimica et biophysica acta. Molecular basis of disease

De Santis S, Porcelli F, Sotgiu G, Crescenzi A, Ceccucci A, Verri M, Caricato M, Taffon C, Orsini M.
PMID: 34600082
Biochim Biophys Acta Mol Basis Dis. 2022 Jan 01;1868(1):166279. doi: 10.1016/j.bbadis.2021.166279. Epub 2021 Sep 30.

The tumor stroma plays a pivotal role in colon cancer genesis and progression. It was observed that collagen fibers in the extracellular matrix (ECM) of cancer stroma, undergo a strong remodeling. These fibrous proteins result more aligned and compact...

Organization, Clinical and Management Indicators on the First Year of Activity of an Outpatient Clinic Dedicated to the Diagnosis and Treatment of Severe Asthma in Italy.

Journal of asthma and allergy

Tognella S, Micheletto C, Roggeri A, Polese G, Artioli D, Senna G, Caminati M, Roggeri DP.
PMID: 34413653
J Asthma Allergy. 2021 Aug 13;14:1011-1018. doi: 10.2147/JAA.S309740. eCollection 2021.

PURPOSE: A Regional Technical Commission was set in 2017 by Veneto region (Italy) to provide opinions and recommendations on drug prescriptions and to implement treatment-pathway guidelines for severe asthma. In this observational study, we describe the first structured, integrated,...

Showing 25 to 36 of 224 entries