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Showing 5293 to 5304 of 5304 entries
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Clinical Significance of Frailty on Treatment Outcome in Nongeriatric Patients With Head and Neck Cancer and Esophageal Cancer Undergoing Curative-Intent Concurrent Chemoradiotherapy.

Cancer control : journal of the Moffitt Cancer Center

Chou WC, Lai CC, Hung CY, Hsueh SW, Yeh KY, Lu CH, Tsang NM, Chang PH, Ho YW, Chen SY, Lin YC, Hung YS.
PMID: 34994207
Cancer Control. 2022 Jan-Dec;29:10732748211045276. doi: 10.1177/10732748211045276.

BACKGROUND: Whether the prevalence of frailty and its clinical significance are relevant to treatment outcomes in younger (aged < 65 years) cancer patients remains uncertain. This study aimed to evaluate the impact of frailty on treatment outcomes in younger...

Impact of High-Dose Irradiation on Human iPSC-Derived Cardiomyocytes Using Multi-Electrode Arrays: Implications for the Antiarrhythmic Effects of Cardiac Radioablation.

International journal of molecular sciences

Kim JS, Choi SW, Park YG, Kim SJ, Choi CH, Cha MJ, Chang JH.
PMID: 35008778
Int J Mol Sci. 2021 Dec 29;23(1). doi: 10.3390/ijms23010351.

Cardiac radioablation is emerging as an alternative option for refractory ventricular arrhythmias. However, the immediate acute effect of high-dose irradiation on human cardiomyocytes remains poorly known. We measured the electrical activities of human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs)...

Metformin-Incorporated Gelatin/Nano-Hydroxyapatite Scaffolds Promotes Bone Regeneration in Critical Size Rat Alveolar Bone Defect Model.

International journal of molecular sciences

Fang CH, Sun CK, Lin YW, Hung MC, Lin HY, Li CH, Lin IP, Chang HC, Sun JS, Chang JZ.
PMID: 35008984
Int J Mol Sci. 2022 Jan 05;23(1). doi: 10.3390/ijms23010558.

In this study, we fabricated gelatin/nano-hydroxyapatite/metformin scaffold (GHMS) and compared its effectiveness in bone regeneration with extraction-only, Sinbone, and Bio-Oss Collagen

Age-Stratified Risk of Dementia in Parkinson's Disease: A Nationwide, Population-Based, Retrospective Cohort Study in Taiwan.

Frontiers in neurology

Chang TY, Yang CP, Chen YH, Lin CH, Chang MH.
PMID: 35002917
Front Neurol. 2021 Dec 24;12:748096. doi: 10.3389/fneur.2021.748096. eCollection 2021.

No abstract available.

Levetiracetam as a sensitizer of concurrent chemoradiotherapy in newly diagnosed glioblastoma: An open-label phase 2 study.

Cancer medicine

Hwang K, Kim J, Kang SG, Jung TY, Kim JH, Kim SH, Kang SH, Hong YK, Kim TM, Kim YJ, Choi BS, Chang JH, Kim CY.
PMID: 34845868
Cancer Med. 2022 Jan;11(2):371-379. doi: 10.1002/cam4.4454. Epub 2021 Nov 30.

BACKGROUND: An open-label single-arm phase 2 study was conducted to evaluate the role of levetiracetam as a sensitizer of concurrent chemoradiotherapy (CCRT) for patients with newly diagnosed glioblastoma. This study aimed to determine the survival benefit of levetiracetam in...

PGC1α is required for the renoprotective effect of lncRNA Tug1 in vivo and links Tug1 with urea cycle metabolites.

Cell reports

Li L, Long J, Mise K, Galvan DL, Overbeek PA, Tan L, Kumar SV, Chan WK, Lorenzi PL, Chang BH, Danesh FR.
PMID: 34380028
Cell Rep. 2021 Aug 10;36(6):109510. doi: 10.1016/j.celrep.2021.109510.

lncRNA taurine-upregulated gene 1 (Tug1) is a promising therapeutic target in the progression of diabetic nephropathy (DN), but the molecular basis of its protection remains poorly understood. Here, we generate a triple-mutant diabetic mouse model coupled with metabolomic profiling...

Diagnostic accuracy of dried blood spots for serology of vaccine-preventable diseases: a systematic review.

Expert review of vaccines

Holroyd TA, Schiaffino F, Chang RH, Wanyiri JW, Saldanha IJ, Gross M, Moss WJ, Hayford K.
PMID: 34852211
Expert Rev Vaccines. 2022 Jan 12;1-16. doi: 10.1080/14760584.2022.2013821. Epub 2022 Jan 12.

INTRODUCTION: Venous serum and plasma are optimal specimens for serological testing but may be logistically infeasible. Dried blood spots (DBS) are a feasible alternative, provided results are adequately sensitive and specific. We aimed to assess the diagnostic accuracy of...

Recovery Profiles of Sevoflurane and Desflurane with or without M-Entropy Guidance in Obese Patients: A Randomized Controlled Trial.

Journal of clinical medicine

Wu YM, Su YH, Huang SY, Lo PH, Chen JT, Chang HC, Yang YL, Cherng YG, Wu HL, Tai YH.
PMID: 35011903
J Clin Med. 2021 Dec 29;11(1). doi: 10.3390/jcm11010162.

Obesity increases the risk of prolonged emergence from general anesthesia due to the delayed release of anesthetic agents from body fat. This trial aimed to evaluate the effects of sevoflurane and desflurane along with anesthetic depth monitoring on emergence...

First report of an adult female patient with endobronchial inflammatory myofibroblastic tumor in Taiwan: A case report.

Thoracic cancer

Lin YT, Huang SH, Chang CH, Hsu PC, Wang CW, Lee CS.
PMID: 34520108
Thorac Cancer. 2021 Oct;12(20):2807-2810. doi: 10.1111/1759-7714.14104. Epub 2021 Sep 14.

An inflammatory myofibroblastic tumor (IMT) of the respiratory system is an uncommon disease. In Taiwan, there is a lack of previous studies on tracheobronchial IMT. The tumor is characterized by overexpression of anaplastic lymphoma receptor tyrosine kinase (ALK)-1. Surgical...

Acute heart failure with dilated cardiomyopathy as the first manifestation of eosinophilic granulomatosis with polyangiitis.

Journal of the European Academy of Dermatology and Venereology : JEADV

Chen YT, Liu WS, Su KY, Hsu YH, Chang CH.
PMID: 34553425
J Eur Acad Dermatol Venereol. 2022 Feb;36(2):e125-e128. doi: 10.1111/jdv.17693. Epub 2021 Oct 02.

No abstract available.

Investigation of Bacterial Community Using 16s rRNA Amplicon Sequencing for Children with Otitis Media Effusion in Korea.

Clinical laboratory

Kim YJ, Jung HW, Choi YS, Chang HK, Kim SH, Yeo SG.
PMID: 35023671
Clin Lab. 2022 Jan 01;68(1). doi: 10.7754/Clin.Lab.2021.210507.

BACKGROUND: Recently, microbiome of otitis media with effusion (OME) was investigated using high throughput sequencing (HTS) in children to discover unbiased causal bacteria and natural otitis media microbiomes. However, there are very few studies in the Asian population, and...

Measuring patient views of physician communication skills: Development and testing of the Communication Assessment Tool.

Krupat E, Makoul G, Chang CH.
UIID-AD: 546
2007;67:333-342. doi: 10.1016/j.pec.2007.05.005.

Objective: Interpersonal and communication skills have been identified as a core competency that must be demonstrated by physicians. We developed and tested a tool that can be used by patients to assess the interpersonal and communication skills of physicians-in-training...

Showing 5293 to 5304 of 5304 entries