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Showing 3121 to 3126 of 3126 entries
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Impact of High-Dose Irradiation on Human iPSC-Derived Cardiomyocytes Using Multi-Electrode Arrays: Implications for the Antiarrhythmic Effects of Cardiac Radioablation.

International journal of molecular sciences

Kim JS, Choi SW, Park YG, Kim SJ, Choi CH, Cha MJ, Chang JH.
PMID: 35008778
Int J Mol Sci. 2021 Dec 29;23(1). doi: 10.3390/ijms23010351.

Cardiac radioablation is emerging as an alternative option for refractory ventricular arrhythmias. However, the immediate acute effect of high-dose irradiation on human cardiomyocytes remains poorly known. We measured the electrical activities of human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs)...

Metformin-Incorporated Gelatin/Nano-Hydroxyapatite Scaffolds Promotes Bone Regeneration in Critical Size Rat Alveolar Bone Defect Model.

International journal of molecular sciences

Fang CH, Sun CK, Lin YW, Hung MC, Lin HY, Li CH, Lin IP, Chang HC, Sun JS, Chang JZ.
PMID: 35008984
Int J Mol Sci. 2022 Jan 05;23(1). doi: 10.3390/ijms23010558.

In this study, we fabricated gelatin/nano-hydroxyapatite/metformin scaffold (GHMS) and compared its effectiveness in bone regeneration with extraction-only, Sinbone, and Bio-Oss Collagen

Levetiracetam as a sensitizer of concurrent chemoradiotherapy in newly diagnosed glioblastoma: An open-label phase 2 study.

Cancer medicine

Hwang K, Kim J, Kang SG, Jung TY, Kim JH, Kim SH, Kang SH, Hong YK, Kim TM, Kim YJ, Choi BS, Chang JH, Kim CY.
PMID: 34845868
Cancer Med. 2022 Jan;11(2):371-379. doi: 10.1002/cam4.4454. Epub 2021 Nov 30.

BACKGROUND: An open-label single-arm phase 2 study was conducted to evaluate the role of levetiracetam as a sensitizer of concurrent chemoradiotherapy (CCRT) for patients with newly diagnosed glioblastoma. This study aimed to determine the survival benefit of levetiracetam in...

Technology of deep brain stimulation: current status and future directions.

Nature reviews. Neurology

Krauss JK, Lipsman N, Aziz T, Boutet A, Brown P, Chang JW, Davidson B, Grill WM, Hariz MI, Horn A, Schulder M, Mammis A, Tass PA, Volkmann J, Lozano AM.
PMID: 33244188
Nat Rev Neurol. 2021 Feb;17(2):75-87. doi: 10.1038/s41582-020-00426-z. Epub 2020 Nov 26.

Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and dystonia, and is also under active investigation for other conditions linked to pathological circuitry,...

Clinical Comparison of Three Sample-to-Answer Systems for Detecting SARS-CoV-2 in B.1.1.7 Lineage Emergence.

Infection and drug resistance

Jian MJ, Chung HY, Chang CK, Lin JC, Yeh KM, Chen CW, Li SY, Hsieh SS, Liu MT, Yang JR, Tang SH, Perng CL, Chang FY, Shang HS.
PMID: 34429623
Infect Drug Resist. 2021 Aug 17;14:3255-3261. doi: 10.2147/IDR.S328327. eCollection 2021.

PURPOSE: Accurate molecular diagnostic assays for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, are needed for epidemiology studies and to support infection-control measures. We evaluated the analytical sensitivity and clinical performance of three...

Investigation of Bacterial Community Using 16s rRNA Amplicon Sequencing for Children with Otitis Media Effusion in Korea.

Clinical laboratory

Kim YJ, Jung HW, Choi YS, Chang HK, Kim SH, Yeo SG.
PMID: 35023671
Clin Lab. 2022 Jan 01;68(1). doi: 10.7754/Clin.Lab.2021.210507.

BACKGROUND: Recently, microbiome of otitis media with effusion (OME) was investigated using high throughput sequencing (HTS) in children to discover unbiased causal bacteria and natural otitis media microbiomes. However, there are very few studies in the Asian population, and...

Showing 3121 to 3126 of 3126 entries