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Showing 97 to 104 of 104 entries
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MYC regulates metabolism through vesicular transfer of glycolytic kinases.

Open biology

Tsakaneli A, Carregari VC, Morini M, Eva A, Cangemi G, Chayka O, Makarov E, Bibbò S, Capone E, Sala G, De Laurenzi V, Poon E, Chesler L, Pieroni L, Larsen MR, Palmisano G, Sala A.
PMID: 34847775
Open Biol. 2021 Dec;11(12):210276. doi: 10.1098/rsob.210276. Epub 2021 Dec 01.

Amplification of the proto-oncogene

The transcription factor XBP1 in memory and cognition: Implications in Alzheimer disease.

Molecular medicine (Cambridge, Mass.)

Cissé M, Duplan E, Checler F.
PMID: 28079229
Mol Med. 2017 Feb;22:905-917. doi: 10.2119/molmed.2016.00229. Epub 2017 Jan 04.

X-box binding protein 1 (XBP1) is a unique basic region leucine zipper transcription factor isolated two decades ago in a search for regulators of major histocompatibility complex class II gene expression. XBP1 is a very complex protein regulating many...

MT5-MMP Promotes Alzheimer's Pathogenesis in the Frontal Cortex of 5xFAD Mice and APP Trafficking .

Frontiers in molecular neuroscience

Baranger K, Bonnet AE, Girard SD, Paumier JM, García-González L, Elmanaa W, Bernard A, Charrat E, Stephan D, Bauer C, Moschke K, Lichtenthaler SF, Roman FS, Checler F, Khrestchatisky M, Rivera S.
PMID: 28119565
Front Mol Neurosci. 2017 Jan 10;9:163. doi: 10.3389/fnmol.2016.00163. eCollection 2016.

We previously reported that deficiency of membrane-type five matrix metalloproteinase (MT5-MMP) prevents amyloid pathology in the cortex and hippocampus of 5xFAD mice, and ameliorates the functional outcome. We have now investigated whether the integrity of another important area affected...

MYC regulates metabolism through vesicular transfer of glycolytic kinases.

Open biology

Tsakaneli A, Carregari VC, Morini M, Eva A, Cangemi G, Chayka O, Makarov E, Bibbò S, Capone E, Sala G, De Laurenzi V, Poon E, Chesler L, Pieroni L, Larsen MR, Palmisano G, Sala A.
PMID: 34847775
Open Biol. 2021 Dec;11(12):210276. doi: 10.1098/rsob.210276. Epub 2021 Dec 01.

Amplification of the proto-oncogene

Multi-Polygenic Analysis of Nicotine Dependence in Individuals of European Ancestry.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco

Risner VA, Benca-Bachman CE, Bertin L, Smith AK, Kaprio J, McGeary JE, Chesler E, Knopik VS, Friedman NP, Palmer RHC.
PMID: 34008017
Nicotine Tob Res. 2021 Nov 05;23(12):2102-2109. doi: 10.1093/ntr/ntab105.

INTRODUCTION: Heritability estimates of nicotine dependence (ND) range from 40% to 70%, but discovery GWAS of ND are underpowered and have limited predictive utility. In this work, we leverage genetically correlated traits and diseases to increase the accuracy of...

Frequency and Prognostic Impact of .

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Bellini A, Pötschger U, Bernard V, Lapouble E, Baulande S, Ambros PF, Auger N, Beiske K, Bernkopf M, Betts DR, Bhalshankar J, Bown N, de Preter K, Clément N, Combaret V, Font de Mora J, George SL, Jiménez I, Jeison M, Marques B, Martinsson T, Mazzocco K, Morini M, Mühlethaler-Mottet A, Noguera R, Pierron G, Rossing M, Taschner-Mandl S, Van Roy N, Vicha A, Chesler L, Balwierz W, Castel V, Elliott M, Kogner P, Laureys G, Luksch R, Malis J, Popovic-Beck M, Ash S, Delattre O, Valteau-Couanet D, Tweddle DA, Ladenstein R, Schleiermacher G.
PMID: 34115544
J Clin Oncol. 2021 Oct 20;39(30):3377-3390. doi: 10.1200/JCO.21.00086. Epub 2021 Jun 11.

PURPOSE: In neuroblastoma (NB), the ALK receptor tyrosine kinase can be constitutively activated through activating point mutations or genomic amplification. We studied MATERIALS AND METHODS: Diagnostic tumor samples were available from 1,092 HR-NBL1/SIOPEN patients to determine RESULTS: Genomic CONCLUSION:...

Novel combination of bioactive agents in bilayered dermal patches provides superior wound healing.

Nanomedicine : nanotechnology, biology, and medicine

Pillai MM, Dandia H, Checker R, Rokade S, Sharma D, Tayalia P.
PMID: 34838992
Nanomedicine. 2021 Nov 26;40:102495. doi: 10.1016/j.nano.2021.102495. Epub 2021 Nov 26.

In present study, multifunctional bilayered dermal patches with antibacterial, antioxidant and anti-inflammatory properties were developed using solvent casting or electrospinning methods and compared for performance. Top layer was made up of polycaprolactone (PCL) and chitosan (CS) while bottom layer...

Resolution of chemical shift anisotropy in .

Journal of magnetic resonance (San Diego, Calif. : 1997)

Kehl A, Hiller M, Hecker F, Tkach I, Dechert S, Bennati M, Meyer A.
PMID: 34749036
J Magn Reson. 2021 Dec;333:107091. doi: 10.1016/j.jmr.2021.107091. Epub 2021 Oct 18.

Pulsed

Showing 97 to 104 of 104 entries