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SN38-based albumin-binding prodrug for efficient targeted cancer chemotherapy.

Journal of controlled release : official journal of the Controlled Release Society

Huang Y, Wang L, Cheng Z, Yang B, Yu J, Chen Y, Lu W.
PMID: 34619226
J Control Release. 2021 Nov 10;339:297-306. doi: 10.1016/j.jconrel.2021.09.040. Epub 2021 Oct 04.

Developing new therapeutic strategies that damage tumour cells without harming normal tissues is among the primary obstacles in chemotherapy. In this study, a novel β-glucuronidase-sensitive albumin-binding prodrug was designed and synthesized to selectively deliver the drug SN38 to tumour...

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Huang Y, Wang L, Cheng Z, et al. SN38-based albumin-binding prodrug for efficient targeted cancer chemotherapy. J Control Release. 2021;339:297-306doi: 10.1016/j.jconrel.2021.09.040.
Huang, Y., Wang, L., Cheng, Z., Yang, B., Yu, J., Chen, Y., & Lu, W. (2021). SN38-based albumin-binding prodrug for efficient targeted cancer chemotherapy. Journal of controlled release : official journal of the Controlled Release Society, 339297-306. https://doi.org/10.1016/j.jconrel.2021.09.040
Huang, Ying, et al. "SN38-based albumin-binding prodrug for efficient targeted cancer chemotherapy." Journal of controlled release : official journal of the Controlled Release Society vol. 339 (2021): 297-306. doi: https://doi.org/10.1016/j.jconrel.2021.09.040
Huang Y, Wang L, Cheng Z, Yang B, Yu J, Chen Y, Lu W. SN38-based albumin-binding prodrug for efficient targeted cancer chemotherapy. J Control Release. 2021 Nov 10;339:297-306. doi: 10.1016/j.jconrel.2021.09.040. Epub 2021 Oct 04. PMID: 34619226.
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Salmonella Pullorum lacking srfA is attenuated, immunogenic and protective in chickens.

Microbial pathogenesis

Yin J, Xiong W, Yuan X, Li S, Zhi L, Pan P, Sun W, Yu T, He Q, Cheng Z.
PMID: 34619313
Microb Pathog. 2021 Dec;161:105230. doi: 10.1016/j.micpath.2021.105230. Epub 2021 Oct 05.

Sallmonella Pullorum is a host-restricted pathogen for poultry and causes severe economic importance in many developing countries. The development of novel vaccines for Salmonella Pullorum is necessary to eradicate the prevalence of the pathogen. In our study, a srfA...

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Yin J, Xiong W, Yuan X, et al. Salmonella Pullorum lacking srfA is attenuated, immunogenic and protective in chickens. Microb Pathog. 2021;161:105230doi: 10.1016/j.micpath.2021.105230.
Yin, J., Xiong, W., Yuan, X., Li, S., Zhi, L., Pan, P., Sun, W., Yu, T., He, Q., & Cheng, Z. (2021). Salmonella Pullorum lacking srfA is attenuated, immunogenic and protective in chickens. Microbial pathogenesis, 161105230. https://doi.org/10.1016/j.micpath.2021.105230
Yin, Junlei, et al. "Salmonella Pullorum lacking srfA is attenuated, immunogenic and protective in chickens." Microbial pathogenesis vol. 161 (2021): 105230. doi: https://doi.org/10.1016/j.micpath.2021.105230
Yin J, Xiong W, Yuan X, Li S, Zhi L, Pan P, Sun W, Yu T, He Q, Cheng Z. Salmonella Pullorum lacking srfA is attenuated, immunogenic and protective in chickens. Microb Pathog. 2021 Dec;161:105230. doi: 10.1016/j.micpath.2021.105230. Epub 2021 Oct 05. PMID: 34619313.
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High glucose protects cardiomyocytes against ischaemia/reperfusion injury by suppressing myocardiocyte apoptosis via circHIPK3/miR-29b/AKT3 signalling.

Journal of cellular and molecular medicine

Cheng N, Jin C, Jin P, Zhu D, Hou Z.
PMID: 33951290
J Cell Mol Med. 2021 May 05; doi: 10.1111/jcmm.16527. Epub 2021 May 05.

High glucose promoted expression of AKT3, a direct target gene of miR-29b, by regulating circHIPK3 that functioned as ceRNA to sponge and down-regulate miR-29b. As a potential target gene of miR-29b, AKT3 plays a crucial role in the pathogenesis...

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Cheng N, Jin C, Jin P, et al. High glucose protects cardiomyocytes against ischaemia/reperfusion injury by suppressing myocardiocyte apoptosis via circHIPK3/miR-29b/AKT3 signalling. J Cell Mol Med. 2021;doi: 10.1111/jcmm.16527.
Cheng, N., Jin, C., Jin, P., Zhu, D., & Hou, Z. (2021). High glucose protects cardiomyocytes against ischaemia/reperfusion injury by suppressing myocardiocyte apoptosis via circHIPK3/miR-29b/AKT3 signalling. Journal of cellular and molecular medicine, . https://doi.org/10.1111/jcmm.16527
Cheng, Nan, et al. "High glucose protects cardiomyocytes against ischaemia/reperfusion injury by suppressing myocardiocyte apoptosis via circHIPK3/miR-29b/AKT3 signalling." Journal of cellular and molecular medicine vol. (2021). doi: https://doi.org/10.1111/jcmm.16527
Cheng N, Jin C, Jin P, Zhu D, Hou Z. High glucose protects cardiomyocytes against ischaemia/reperfusion injury by suppressing myocardiocyte apoptosis via circHIPK3/miR-29b/AKT3 signalling. J Cell Mol Med. 2021 May 05; doi: 10.1111/jcmm.16527. Epub 2021 May 05. PMID: 33951290; PMCID: PMC8406489.
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Effects of fertilizer practice on fungal and actinobacterial cellulolytic community with different humified particle-size fractions in double-cropping field.

Scientific reports

Tang H, Li C, Xu Y, Cheng K, Shi L, Wen L, Li W, Xiao X.
PMID: 34531457
Sci Rep. 2021 Sep 16;11(1):18441. doi: 10.1038/s41598-021-97975-0.

Cellulose plays an important role in maintaining or improving soil carbon (C) cycling and soil fertility of paddy field. There had close relationship between functional cellulose genes (cbhI and GH48) with characterize of soil organic matter chemical components (fulvic...

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Tang H, Li C, Xu Y, et al. Effects of fertilizer practice on fungal and actinobacterial cellulolytic community with different humified particle-size fractions in double-cropping field. Sci Rep. 2021;11(1):18441doi: 10.1038/s41598-021-97975-0.
Tang, H., Li, C., Xu, Y., Cheng, K., Shi, L., Wen, L., Li, W., & Xiao, X. (2021). Effects of fertilizer practice on fungal and actinobacterial cellulolytic community with different humified particle-size fractions in double-cropping field. Scientific reports, 11(1), 18441. https://doi.org/10.1038/s41598-021-97975-0
Tang, Haiming, et al. "Effects of fertilizer practice on fungal and actinobacterial cellulolytic community with different humified particle-size fractions in double-cropping field." Scientific reports vol. 11,1 (2021): 18441. doi: https://doi.org/10.1038/s41598-021-97975-0
Tang H, Li C, Xu Y, Cheng K, Shi L, Wen L, Li W, Xiao X. Effects of fertilizer practice on fungal and actinobacterial cellulolytic community with different humified particle-size fractions in double-cropping field. Sci Rep. 2021 Sep 16;11(1):18441. doi: 10.1038/s41598-021-97975-0. PMID: 34531457; PMCID: PMC8446020.
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Study of the Correlation Between the Ratio of Diastolic to Systolic Durations and Echocardiography Measurements and Its Application to the Classification of Heart Failure Phenotypes.

International journal of general medicine

Cheng L, Liao K, Wang Y, Lv F, Guo X, Zheng Y, Qin J.
PMID: 34531677
Int J Gen Med. 2021 Sep 10;14:5493-5503. doi: 10.2147/IJGM.S324319. eCollection 2021.

BACKGROUND: This study aimed to investigate the correlation between the ratio of diastolic to systolic durations (D/S) and echocardiographic parameters of patients with chronic heart failure (CHF) and evaluate whether the D/S can be used as a supplementary biomarker...

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Cheng L, Liao K, Wang Y, et al. Study of the Correlation Between the Ratio of Diastolic to Systolic Durations and Echocardiography Measurements and Its Application to the Classification of Heart Failure Phenotypes. Int J Gen Med. 2021;14:5493-5503doi: 10.2147/IJGM.S324319.
Cheng, L., Liao, K., Wang, Y., Lv, F., Guo, X., Zheng, Y., & Qin, J. (2021). Study of the Correlation Between the Ratio of Diastolic to Systolic Durations and Echocardiography Measurements and Its Application to the Classification of Heart Failure Phenotypes. International journal of general medicine, 145493-5503. https://doi.org/10.2147/IJGM.S324319
Cheng, Lifang, et al. "Study of the Correlation Between the Ratio of Diastolic to Systolic Durations and Echocardiography Measurements and Its Application to the Classification of Heart Failure Phenotypes." International journal of general medicine vol. 14 (2021): 5493-5503. doi: https://doi.org/10.2147/IJGM.S324319
Cheng L, Liao K, Wang Y, Lv F, Guo X, Zheng Y, Qin J. Study of the Correlation Between the Ratio of Diastolic to Systolic Durations and Echocardiography Measurements and Its Application to the Classification of Heart Failure Phenotypes. Int J Gen Med. 2021 Sep 10;14:5493-5503. doi: 10.2147/IJGM.S324319. eCollection 2021. PMID: 34531677; PMCID: PMC8439664.
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Impaired static postural control correlates to the contraction ability of trunk muscle in young adults with chronic non-specific low back pain: A cross-sectional study.

Gait & posture

Wang H, Zheng J, Fan Z, Luo Z, Wu Y, Cheng X, Yang J, Zhang S, Yu Q, Lo WLA, Wang C.
PMID: 34823100
Gait Posture. 2021 Nov 19;92:44-50. doi: 10.1016/j.gaitpost.2021.11.021. Epub 2021 Nov 19.

INTRODUCTION: Patients with chronic non-specific low back pain (CNSLBP) were found with impaired postural control in previous studies. Since the trunk muscle take important efforts on core stability, the study aimed to examine the relationships of postural control during...

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Wang H, Zheng J, Fan Z, et al. Impaired static postural control correlates to the contraction ability of trunk muscle in young adults with chronic non-specific low back pain: A cross-sectional study. Gait Posture. 2021;92:44-50doi: 10.1016/j.gaitpost.2021.11.021.
Wang, H., Zheng, J., Fan, Z., Luo, Z., Wu, Y., Cheng, X., Yang, J., Zhang, S., Yu, Q., Lo, W. L. A., & Wang, C. (2021). Impaired static postural control correlates to the contraction ability of trunk muscle in young adults with chronic non-specific low back pain: A cross-sectional study. Gait & posture, 9244-50. https://doi.org/10.1016/j.gaitpost.2021.11.021
Wang, Hongjiang, et al. "Impaired static postural control correlates to the contraction ability of trunk muscle in young adults with chronic non-specific low back pain: A cross-sectional study." Gait & posture vol. 92 (2021): 44-50. doi: https://doi.org/10.1016/j.gaitpost.2021.11.021
Wang H, Zheng J, Fan Z, Luo Z, Wu Y, Cheng X, Yang J, Zhang S, Yu Q, Lo WLA, Wang C. Impaired static postural control correlates to the contraction ability of trunk muscle in young adults with chronic non-specific low back pain: A cross-sectional study. Gait Posture. 2021 Nov 19;92:44-50. doi: 10.1016/j.gaitpost.2021.11.021. Epub 2021 Nov 19. PMID: 34823100.
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Na.

Neuroscience letters

Farhat E, Devereaux MEM, Cheng H, Weber JM, Pamenter ME.
PMID: 34530116
Neurosci Lett. 2021 Nov 01;764:136244. doi: 10.1016/j.neulet.2021.136244. Epub 2021 Sep 14.

Matching ATP supply and demand is key to neuronal hypoxia-tolerance and failure to achieve this balance leads to excitotoxic cell death in most adult mammalian brains. Ion pumping is the most energy-demanding process in the brain and some hypoxia-tolerant...

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Farhat E, Devereaux MEM, Cheng H, et al. Na. Neurosci Lett. 2021;764:136244doi: 10.1016/j.neulet.2021.136244.
Farhat, E., Devereaux, M. E. M., Cheng, H., Weber, J. M., & Pamenter, M. E. (2021). Na. Neuroscience letters, 764136244. https://doi.org/10.1016/j.neulet.2021.136244
Farhat, Elie, et al. "Na." Neuroscience letters vol. 764 (2021): 136244. doi: https://doi.org/10.1016/j.neulet.2021.136244
Farhat E, Devereaux MEM, Cheng H, Weber JM, Pamenter ME. Na. Neurosci Lett. 2021 Nov 01;764:136244. doi: 10.1016/j.neulet.2021.136244. Epub 2021 Sep 14. PMID: 34530116.
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Organic Photocathode Supported by Copper Nanosheets Array for Overall Water Splitting.

Chemistry (Weinheim an der Bergstrasse, Germany)

Zhang R, Sun X, Zheng L, Diao L, Chen F, Li Y, Wang S, Wang Y, Wang W, Lu F, Dong H, Liu H, Cheng Y.
PMID: 34859914
Chemistry. 2021 Dec 03;e202103495. doi: 10.1002/chem.202103495. Epub 2021 Dec 03.

The Z-scheme overall solar water splitting is a mimic of natural photosynthesis to convert solar energy into chemical energy. Since the energy levels of most organic semiconductors match well with the hydrogen evolution potential, they have great application prospects...

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Zhang R, Sun X, Zheng L, et al. Organic Photocathode Supported by Copper Nanosheets Array for Overall Water Splitting. Chemistry. 2021;e202103495doi: 10.1002/chem.202103495.
Zhang, R., Sun, X., Zheng, L., Diao, L., Chen, F., Li, Y., Wang, S., Wang, Y., Wang, W., Lu, F., Dong, H., Liu, H., & Cheng, Y. (2021). Organic Photocathode Supported by Copper Nanosheets Array for Overall Water Splitting. Chemistry (Weinheim an der Bergstrasse, Germany), e202103495. https://doi.org/10.1002/chem.202103495
Zhang, Rui, et al. "Organic Photocathode Supported by Copper Nanosheets Array for Overall Water Splitting." Chemistry (Weinheim an der Bergstrasse, Germany) vol. (2021): e202103495. doi: https://doi.org/10.1002/chem.202103495
Zhang R, Sun X, Zheng L, Diao L, Chen F, Li Y, Wang S, Wang Y, Wang W, Lu F, Dong H, Liu H, Cheng Y. Organic Photocathode Supported by Copper Nanosheets Array for Overall Water Splitting. Chemistry. 2021 Dec 03;e202103495. doi: 10.1002/chem.202103495. Epub 2021 Dec 03. PMID: 34859914.
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Compact integrator design for short-distance sharp and unconventional geometric irradiance tailoring.

Applied optics

Liu Y, Cheng D, Hou Q, Chen H, Feng Z, Yang T, Wang Y.
PMID: 33983169
Appl Opt. 2021 May 10;60(14):4165-4176. doi: 10.1364/AO.422384.

A compact microlens array (MLA) integral homogenizer composed of a projection MLA, a condenser MLA, and a subimage array mask based on Kohler illumination is presented herein. By adopting the optimal design of an aspheric projection sublens, a short-distance...

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Liu Y, Cheng D, Hou Q, et al. Compact integrator design for short-distance sharp and unconventional geometric irradiance tailoring. Appl Opt. 2021;60(14):4165-4176doi: 10.1364/AO.422384.
Liu, Y., Cheng, D., Hou, Q., Chen, H., Feng, Z., Yang, T., & Wang, Y. (2021). Compact integrator design for short-distance sharp and unconventional geometric irradiance tailoring. Applied optics, 60(14), 4165-4176. https://doi.org/10.1364/AO.422384
Liu, Yue, et al. "Compact integrator design for short-distance sharp and unconventional geometric irradiance tailoring." Applied optics vol. 60,14 (2021): 4165-4176. doi: https://doi.org/10.1364/AO.422384
Liu Y, Cheng D, Hou Q, Chen H, Feng Z, Yang T, Wang Y. Compact integrator design for short-distance sharp and unconventional geometric irradiance tailoring. Appl Opt. 2021 May 10;60(14):4165-4176. doi: 10.1364/AO.422384. PMID: 33983169.
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Systemic Immune-Inflammation Index Predicts Delayed Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage.

Neurosurgery

Geraghty JR, Lung TJ, Hirsch Y, Katz EA, Cheng T, Saini NS, Pandey DK, Testai FD.
PMID: 34560777
Neurosurgery. 2021 Nov 18;89(6):1071-1079. doi: 10.1093/neuros/nyab354.

BACKGROUND: Delayed cerebral vasospasm is a feared complication of aneurysmal subarachnoid hemorrhage (SAH).OBJECTIVE: To investigate the relationship of systemic inflammation, measured using the systemic immune-inflammation (SII) index, with delayed angiographic or sonographic vasospasm. We hypothesize that early elevations in...

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Geraghty JR, Lung TJ, Hirsch Y, et al. Systemic Immune-Inflammation Index Predicts Delayed Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage. Neurosurgery. 2021;89(6):1071-1079doi: 10.1093/neuros/nyab354.
Geraghty, J. R., Lung, T. J., Hirsch, Y., Katz, E. A., Cheng, T., Saini, N. S., Pandey, D. K., & Testai, F. D. (2021). Systemic Immune-Inflammation Index Predicts Delayed Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage. Neurosurgery, 89(6), 1071-1079. https://doi.org/10.1093/neuros/nyab354
Geraghty, Joseph R, et al. "Systemic Immune-Inflammation Index Predicts Delayed Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage." Neurosurgery vol. 89,6 (2021): 1071-1079. doi: https://doi.org/10.1093/neuros/nyab354
Geraghty JR, Lung TJ, Hirsch Y, Katz EA, Cheng T, Saini NS, Pandey DK, Testai FD. Systemic Immune-Inflammation Index Predicts Delayed Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage. Neurosurgery. 2021 Nov 18;89(6):1071-1079. doi: 10.1093/neuros/nyab354. PMID: 34560777; PMCID: PMC8600162.
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A fundamental theoretical study on the different effect of electroporation on tumor blood vessels and normal blood vessels.

Bioelectrochemistry (Amsterdam, Netherlands)

Lv Y, Feng Z, Chen S, Cheng X, Zhang J, Yao C.
PMID: 34902663
Bioelectrochemistry. 2021 Dec 02;144:108010. doi: 10.1016/j.bioelechem.2021.108010. Epub 2021 Dec 02.

Electroporation achieved by the application of pulsed electric field is successfully used for clinical tumor ablation. Electrochemotherapy (ECT) and irreversible electroporation (IRE), which are two protocols based on electroporation, have been shown to ablate only tumor cells while preserving...

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Lv Y, Feng Z, Chen S, et al. A fundamental theoretical study on the different effect of electroporation on tumor blood vessels and normal blood vessels. Bioelectrochemistry. 2021;144:108010doi: 10.1016/j.bioelechem.2021.108010.
Lv, Y., Feng, Z., Chen, S., Cheng, X., Zhang, J., & Yao, C. (2021). A fundamental theoretical study on the different effect of electroporation on tumor blood vessels and normal blood vessels. Bioelectrochemistry (Amsterdam, Netherlands), 144108010. https://doi.org/10.1016/j.bioelechem.2021.108010
Lv, Yanpeng, et al. "A fundamental theoretical study on the different effect of electroporation on tumor blood vessels and normal blood vessels." Bioelectrochemistry (Amsterdam, Netherlands) vol. 144 (2021): 108010. doi: https://doi.org/10.1016/j.bioelechem.2021.108010
Lv Y, Feng Z, Chen S, Cheng X, Zhang J, Yao C. A fundamental theoretical study on the different effect of electroporation on tumor blood vessels and normal blood vessels. Bioelectrochemistry. 2021 Dec 02;144:108010. doi: 10.1016/j.bioelechem.2021.108010. Epub 2021 Dec 02. PMID: 34902663.
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A kinome screen reveals that Nemo-like kinase is a key suppressor of hepatic gluconeogenesis.

Cell metabolism

Ji YX, Wang Y, Li PL, Cai L, Wang XM, Bai L, Liu Z, Tian H, Tian S, Zhang P, Zhang XJ, Cheng X, Yuan Y, She ZG, Hu Y, Li H.
PMID: 33951476
Cell Metab. 2021 Jun 01;33(6):1171-1186.e9. doi: 10.1016/j.cmet.2021.04.006. Epub 2021 May 04.

Antihyperglycemic therapy is an important priority for the treatment of type 2 diabetes (T2D). Excessive hepatic glucose production (HGP) is a major cause of fasting hyperglycemia. Therefore, a better understanding of its regulation would be important to develop effective...

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Ji YX, Wang Y, Li PL, et al. A kinome screen reveals that Nemo-like kinase is a key suppressor of hepatic gluconeogenesis. Cell Metab. 2021;33(6):1171-1186.e9doi: 10.1016/j.cmet.2021.04.006.
Ji, Y. X., Wang, Y., Li, P. L., Cai, L., Wang, X. M., Bai, L., Liu, Z., Tian, H., Tian, S., Zhang, P., Zhang, X. J., Cheng, X., Yuan, Y., She, Z. G., Hu, Y., & Li, H. (2021). A kinome screen reveals that Nemo-like kinase is a key suppressor of hepatic gluconeogenesis. Cell metabolism, 33(6), 1171-1186.e9. https://doi.org/10.1016/j.cmet.2021.04.006
Ji, Yan-Xiao, et al. "A kinome screen reveals that Nemo-like kinase is a key suppressor of hepatic gluconeogenesis." Cell metabolism vol. 33,6 (2021): 1171-1186.e9. doi: https://doi.org/10.1016/j.cmet.2021.04.006
Ji YX, Wang Y, Li PL, Cai L, Wang XM, Bai L, Liu Z, Tian H, Tian S, Zhang P, Zhang XJ, Cheng X, Yuan Y, She ZG, Hu Y, Li H. A kinome screen reveals that Nemo-like kinase is a key suppressor of hepatic gluconeogenesis. Cell Metab. 2021 Jun 01;33(6):1171-1186.e9. doi: 10.1016/j.cmet.2021.04.006. Epub 2021 May 04. PMID: 33951476.
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Showing 9985 to 9996 of 30724 entries