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Showing 433 to 436 of 436 entries
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Intracellular AGR2 transduces PGE2 stimuli to promote epithelial-mesenchymal transition and metastasis of colorectal cancer.

Cancer letters

Zhang H, Chi J, Hu J, Ji T, Luo Z, Zhou C, Huang L, Dai Z, Li J, Wang G, Wang L, Wang Z.
PMID: 34216690
Cancer Lett. 2021 Oct 10;518:180-195. doi: 10.1016/j.canlet.2021.06.025. Epub 2021 Jun 30.

Human anterior gradient homolog 2 (AGR2) reportedly acts as an oncogene in multiple types of cancers. As a secreted protein, the oncogenic roles of extracellular AGR2 have been the focus of the increasing number of studies. In contrast, the...

Dexamethasone Versus Prednisone or Prednisolone for Acute Pediatric Asthma Exacerbations in the Emergency Department: A Meta-Analysis.

Pediatric emergency care

Cai KJ, Su SQ, Wang YG, Zeng YM.
PMID: 32149991
Pediatr Emerg Care. 2021 Dec 01;37(12):e1139-e1144. doi: 10.1097/PEC.0000000000001926.

OBJECTIVE: This study evaluates the efficacy and tolerability of dexamethasone (DEX) as an alternative to prednisone/prednisolone (PRED) for the treatment of pediatric asthma exacerbations in emergency department (ED).METHODS: Fixed-effects meta-analyses of selected endpoints were performed by using data taken...

Prevalence of suicidal ideation and suicide attempt among patients with traumatic brain injury: A meta-analysis.

Journal of affective disorders

Chen F, Chi J, Niu F, Gao Q, Mei F, Zhao L, Hu K, Zhao B, Ma B.
PMID: 34995702
J Affect Disord. 2022 Jan 04;300:349-357. doi: 10.1016/j.jad.2022.01.024. Epub 2022 Jan 04.

BACKGROUND: Suicidality is common among patients with traumatic brain injury (TBI). This meta-analysis aimed to assess the prevalence of suicidal ideation (SI) and suicide attempt (SA) in TBI patients.METHODS: Databases including PubMed, Cochrane Library, Embase, CINAHL, Web of Science,...

Population pharmacokinetic model-guided optimization of intravenous voriconazole dosing regimens in critically ill patients with liver dysfunction.

Pharmacotherapy

Lin XB, Lui KY, Guo PH, Liu XM, Liang T, Hu XG, Tong L, Wu JJ, Xia YZ, Chen P, Zhong GP, Chen X, Cai CJ.
PMID: 34655497
Pharmacotherapy. 2022 Jan;42(1):23-33. doi: 10.1002/phar.2634. Epub 2021 Oct 25.

STUDY OBJECTIVES: This study aimed to establish a population pharmacokinetic (PPK) model of intravenous voriconazole (VRC) in critically ill patients with liver dysfunction and to explore the optimal dosing strategies in specific clinical scenarios for invasive fungal infections (IFIs)...

Showing 433 to 436 of 436 entries