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Showing 169 to 179 of 179 entries
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Nematic twist-bend phase in an external field.

Proceedings of the National Academy of Sciences of the United States of America

Pająk G, Longa L, Chrzanowska A.
PMID: 30309960
Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10303-E10312. doi: 10.1073/pnas.1721786115. Epub 2018 Oct 11.

The response of the nematic twist-bend ([Formula: see text]) phase to an applied field can provide important insight into the structure of this liquid and may bring us closer to understanding mechanisms generating mirror symmetry breaking in a fluid...

Nanotechnology for a Sustainable Future: Addressing Global Challenges with the International Network4Sustainable Nanotechnology.

ACS nano

Pokrajac L, Abbas A, Chrzanowski W, Dias GM, Eggleton BJ, Maguire S, Maine E, Malloy T, Nathwani J, Nazar L, Sips A, Sone J, van den Berg A, Weiss PS, Mitra S.
PMID: 34910476
ACS Nano. 2021 Dec 28;15(12):18608-18623. doi: 10.1021/acsnano.1c10919. Epub 2021 Dec 15.

Nanotechnology has important roles to play in international efforts in sustainability. We discuss how current and future capabilities in nanotechnology align with and support the United Nations' Sustainable Development Goals. We argue that, as a field, we can accelerate...

Feasibility of Cobalt-Free Nanostructured WC Cutting Inserts for Machining of a TiC/Fe Composite.

Materials (Basel, Switzerland)

Gevorkyan E, Rucki M, Sałaciński T, Siemiątkowski Z, Nerubatskyi V, Kucharczyk W, Chrzanowski J, Gutsalenko Y, Nejman M.
PMID: 34205711
Materials (Basel). 2021 Jun 21;14(12). doi: 10.3390/ma14123432.

The paper presents results of investigations on the binderless nanostructured tungsten carbide (WC) cutting tools fabrication and performance. The scientific novelty includes the description of some regularities of the powder consolidation under electric current and the subsequent possibility to...

Cardiovascular risk factors among cancer patients qualified for systemic treatment. Analysis of a cardiovascular disease-free cohort from the Polish multicentre study ONCOECHO.

Archives of medical science : AMS

Nowakowska M, Płońska-Gościniak E, Szyszka A, Chrzanowski Ł, Krakowska M, Potemski P, Mizia-Stec K, Gąsior Z, Bodys A, Siński M, Gościńska-Szmagała A, Gościniak P, Różewicz M, Zaborska B, Braksator W, Kosior D, Kasprzak JD.
PMID: 33224328
Arch Med Sci. 2020 Nov 02;16(6):1295-1303. doi: 10.5114/aoms.2020.100401. eCollection 2020.

INTRODUCTION: Cancer therapies are currently more efficient at increasing the survival of patients (pts) with cancer. Unfortunately, the cardiovascular (CV) complications of cancer therapies may adversely affect improving results of treatment. The aim of the study was to evaluate...

Can the Hole-Board Test Predict a Rat's Exploratory Behavior in a Free-Exploration Test?.

Animals : an open access journal from MDPI

Pisula W, Modlinska K, Goncikowska K, Chrzanowska A.
PMID: 33918826
Animals (Basel). 2021 Apr 09;11(4). doi: 10.3390/ani11041068.

This study focuses on the rat activity in a hole-board setting that we considered a type of exploratory behavior. The general hypothesis is based on the claim that a motivational mechanism is central to both the response to novelty...

The Cytotoxic Effect of Copper (II) Complexes with Halogenated 1,3-Disubstituted Arylthioureas on Cancer and Bacterial Cells.

International journal of molecular sciences

Chrzanowska A, Drzewiecka-Antonik A, Dobrzyńska K, Stefańska J, Pietrzyk P, Struga M, Bielenica A.
PMID: 34768844
Int J Mol Sci. 2021 Oct 22;22(21). doi: 10.3390/ijms222111415.

A series of eight copper (II) complexes with 3-(4-chloro-3-nitrophenyl)thiourea were designed and synthesized. The cytotoxic activity of all compounds was assessed in three human cancer cell lines (SW480, SW620, PC3) and human normal keratinocytes (HaCaT). The complexes

Distinct Signaling Functions of Rap1 Isoforms in NO Release From Endothelium.

Frontiers in cell and developmental biology

Kosuru R, Singh B, Lakshmikanthan S, Nishijima Y, Vasquez-Vivar J, Zhang DX, Chrzanowska M.
PMID: 34222255
Front Cell Dev Biol. 2021 Jun 17;9:687598. doi: 10.3389/fcell.2021.687598. eCollection 2021.

Small GTPase Rap1 plays a prominent role in endothelial cell (EC) homeostasis by promoting NO release. Endothelial deletion of the two highly homologous Rap1 isoforms, Rap1A and Rap1B, leads to endothelial dysfunction

Made by cells for cells - extracellular vesicles as next-generation mainstream medicines.

Journal of cell science

Phan TH, Kim SY, Rudge C, Chrzanowski W.
PMID: 35019142
J Cell Sci. 2022 Jan 01;135(1). doi: 10.1242/jcs.259166. Epub 2022 Jan 12.

Current medicine has only taken us so far in reducing disease and tissue damage. Extracellular vesicles (EVs), which are membranous nanostructures produced naturally by cells, have been hailed as a next-generation medicine. EVs deliver various biomolecules, including proteins, lipids...

Compritol solid lipid nanoparticle formulations enhance the protective effect of betulinic acid derivatives in human Müller cells against oxidative injury.

Experimental eye research

Cheng Z, Li Y, Wang K, Zhu X, Tharkar P, Shu W, Zhang T, Zeng S, Zhu L, Murray M, Chrzanowski W, Zhou F.
PMID: 34953864
Exp Eye Res. 2021 Dec 23;215:108906. doi: 10.1016/j.exer.2021.108906. Epub 2021 Dec 23.

Müller cells maintain homeostatic functions in the retina. Their dysfunction leads to irreversible retinal diseases. Oxidative injury is a leading cause of retinal cytotoxicity. Our previous studies reported several betulinic acid (BA) derivatives can protect Müller cells from oxidative...

Myocardial Viability Assessment Before Surgical Revascularization in Ischemic Cardiomyopathy: JACC Review Topic of the Week.

Journal of the American College of Cardiology

Panza JA, Chrzanowski L, Bonow RO.
PMID: 34474740
J Am Coll Cardiol. 2021 Sep 07;78(10):1068-1077. doi: 10.1016/j.jacc.2021.07.004.

Ischemic cardiomyopathy results from the combination of scar with fibrosis replacement and areas of dysfunctional but viable myocardium that may improve contractile function with revascularization. Observational studies reported that only patients with substantial amounts of myocardial viability had better...

Attrition in Graduate School Versus Other Health Professional Programs: Etiologies and Solutions.

Medical science educator

Chrzanowski SM, Poudyal R.
PMID: 34457484
Med Sci Educ. 2018 Dec 19;29(1):329-331. doi: 10.1007/s40670-018-00673-2. eCollection 2019 Mar.

Data suggests significantly higher attrition rates of graduate students compared to other health professional programs. Several key differences exist between the training paradigm of Ph.D. programs and other health professional fields, such as the dynamics of group training, differences...

Showing 169 to 179 of 179 entries