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Showing 25 to 36 of 176 entries
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The crystalline state as a dynamic system: IR microspectroscopy under electrochemical control for a [NiFe] hydrogenase.

Chemical science

Ash PA, Kendall-Price SET, Evans RM, Carr SB, Brasnett AR, Morra S, Rowbotham JS, Hidalgo R, Healy AJ, Cinque G, Frogley MD, Armstrong FA, Vincent KA.
PMID: 34745526
Chem Sci. 2021 Jun 03;12(39):12959-12970. doi: 10.1039/d1sc01734a. eCollection 2021 Oct 13.

Controlled formation of catalytically-relevant states within crystals of complex metalloenzymes represents a significant challenge to structure-function studies. Here we show how electrochemical control over single crystals of [NiFe] hydrogenase 1 (Hyd1) from

Setting for "Normal" Serum Ferritin Levels in Patients with Transfusion-Dependent Thalassemia: Our Current Strategy.

Journal of clinical medicine

Spasiano A, Meloni A, Costantini S, Quaia E, Cademartiri F, Cinque P, Pepe A, Ricchi P.
PMID: 34945281
J Clin Med. 2021 Dec 20;10(24). doi: 10.3390/jcm10245985.

This cross-sectional study aimed to establish the association between serum ferritin levels and organ iron overload (IO) and overall morbidity in transfusion-dependent thalassemia (TDT) patients. One hundred and three TDT patients (40.03 ± 9.15 years; 57.3% females) with serum...

Cerebrospinal Fluid viral load across the spectrum of untreated HIV-1 infection: a cross-sectional multi-center study.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Ulfhammer G, Edén A, Antinori A, Brew BJ, Calcagno A, Cinque P, De Zan V, Hagberg L, Lin A, Nilsson S, Oprea C, Pinnetti C, Spudich S, Trunfio M, Winston A, Price RW, Gisslén M.
PMID: 34747481
Clin Infect Dis. 2021 Nov 08; doi: 10.1093/cid/ciab943. Epub 2021 Nov 08.

BACKGROUND: The aim of this large multicenter study was to determine variations in cerebrospinal fluid (CSF) HIV-RNA in different phases of untreated HIV-1 infection and its associations with plasma HIV-RNA and other biomarkers.METHODS: Treatment naïve adults with available CSF...

hnRNPA1/UP1 Unfolds .

ACS omega

Ferino A, Marquevielle J, Choudhary H, Cinque G, Robert C, Bourdoncle A, Picco R, Mergny JL, Salgado GF, Xodo LE.
PMID: 34926957
ACS Omega. 2021 Nov 30;6(49):34092-34106. doi: 10.1021/acsomega.1c05538. eCollection 2021 Dec 14.

Recent studies have proven that the genetic landscape of pancreatic cancer is dominated by the

An interactive and low-cost full body rehabilitation framework based on 3D immersive serious games.

Journal of biomedical informatics

Avola D, Cinque L, Foresti GL, Marini MR.
PMID: 30521854
J Biomed Inform. 2019 Jan;89:81-100. doi: 10.1016/j.jbi.2018.11.012. Epub 2018 Dec 03.

Strokes, surgeries, or degenerative diseases can impair motor abilities and balance. Long-term rehabilitation is often the only way to recover, as completely as possible, these lost skills. To be effective, this type of rehabilitation should follow three main rules....

Rare Somatic MEN1 Gene Pathogenic Variant in a Patient Affected by Atypical Parathyroid Adenoma.

International journal of endocrinology

Cinque L, Pugliese F, Clemente C, Castellana S, Leone MP, de Martino D, Balsamo T, Battista C, Biagini T, Graziano P, Castori M, Scillitani A, Guarnieri V.
PMID: 32411220
Int J Endocrinol. 2020 Apr 27;2020:2080797. doi: 10.1155/2020/2080797. eCollection 2020.

OBJECTIVE: Atypical parathyroid adenoma is a rare neoplasm, showing atypical histological features intermediate between classic benign adenoma and the rarest parathyroid carcinoma, whose the clinical behaviour and outcome is not yet understood or predictable. Up to date only two...

Polyamorphism Mirrors Polymorphism in the Liquid-Liquid Transition of a Molecular Liquid.

Journal of the American Chemical Society

Walton F, Bolling J, Farrell A, MacEwen J, Syme CD, Jiménez MG, Senn HM, Wilson C, Cinque G, Wynne K.
PMID: 32249557
J Am Chem Soc. 2020 Apr 22;142(16):7591-7597. doi: 10.1021/jacs.0c01712. Epub 2020 Apr 13.

Liquid-liquid transitions between two amorphous phases in a single-component liquid have courted controversy. All known examples of liquid-liquid transitions in molecular liquids have been observed in the supercooled state, suggesting an intimate connection with vitrification and locally favored structures...

Infrared spectra of micro-structured samples with microPhotoacoustic spectroscopy and synchrotron radiation.

The Analyst

Michaelian KH, Frogley MD, Cinque G, Quaroni L.
PMID: 31868866
Analyst. 2020 Feb 17;145(4):1483-1490. doi: 10.1039/c9an01281h.

Photoacoustic spectroscopy (PAS) measures the photon absorption spectrum of a sample through detection of the acoustic wave generated by the photothermal effect as one modulates the intensity of the incident radiation at each wavelength. We have recently demonstrated the...

Novel Pathogenic Variants of the AIRE Gene in Two Autoimmune Polyendocrine Syndrome Type I Cases with Atypical Presentation: Role of the NGS in Diagnostic Pathway and Review of the Literature.

Biomedicines

Cinque L, Angeletti C, Orrico A, Castellana S, Ferrito L, Ciuoli C, Mazza T, Castori M, Guarnieri V.
PMID: 33352647
Biomedicines. 2020 Dec 19;8(12). doi: 10.3390/biomedicines8120631.

No abstract available.

A light CNN for detecting COVID-19 from CT scans of the chest.

Pattern recognition letters

Polsinelli M, Cinque L, Placidi G.
PMID: 33041409
Pattern Recognit Lett. 2020 Dec;140:95-100. doi: 10.1016/j.patrec.2020.10.001. Epub 2020 Oct 03.

Computer Tomography (CT) imaging of the chest is a valid diagnosis tool to detect COVID-19 promptly and to control the spread of the disease. In this work we propose a light Convolutional Neural Network (CNN) design, based on the...

Rapid discovery of diverse neutralizing SARS-CoV-2 antibodies from large-scale synthetic phage libraries.

mAbs

Yuan TZ, Garg P, Wang L, Willis JR, Kwan E, Hernandez AGL, Tuscano E, Sever EN, Keane E, Soto C, Mucker EM, Fouch ME, Davidson E, Doranz BJ, Kailasan S, Aman MJ, Li H, Hooper JW, Saphire EO, Crowe JE, Liu Q, Axelrod F, Sato AK.
PMID: 34967699
MAbs. 2022 Jan-Dec;14(1):2002236. doi: 10.1080/19420862.2021.2002236.

Coronavirus disease 2019 (COVID-19) is an evolving global public health crisis in need of therapeutic options. Passive immunization of monoclonal antibodies (mAbs) represents a promising therapeutic strategy capable of conferring immediate protection from SARS-CoV-2 infection. Herein, we describe the...

Probing active galactic nuclei with H2O megamasers.

Proceedings of the National Academy of Sciences of the United States of America

Moran J, Greenhill L, Herrnstein J, Diamond P, Miyoshi M, Nakai N, Inque M.
PMID: 11607612
Proc Natl Acad Sci U S A. 1995 Dec 05;92(25):11427-33. doi: 10.1073/pnas.92.25.11427.

We describe the characteristics of the rapidly rotating molecular disk in the nucleus of the mildly active galaxy NGC4258. The morphology and kinematics of the disk are delineated by the point-like watervapor emission sources at 1.35-cm wavelength. High angular...

Showing 25 to 36 of 176 entries