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Showing 109 to 115 of 115 entries
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Prospective Evaluation of Radiculitis following Bone Morphogenetic Protein-2 Use for Transforaminal Interbody Arthrodesis in Spine Surgery.

Asian spine journal

Sebastian AS, Wanderman NR, Currier BL, Pichelmann MA, Treder VM, Fogelson JL, Clarke MJ, Nassr AN.
PMID: 30866616
Asian Spine J. 2019 Mar 15;13(4):544-555. doi: 10.31616/asj.2018.0277. Print 2019 Aug.

STUDY DESIGN: Prospective observational cohort study.PURPOSE: This study aims to evaluate the safety and efficacy of bone morphogenetic protein-2 (BMP-2) in transforaminal lumbar interbody fusion (TLIF) with regard to postoperative radiculitis.OVERVIEW OF LITERATURE: Bone morphogenetic protein (BMP) is being...

Membrane compartmentalisation of the ubiquitin system.

Seminars in cell & developmental biology

Rusilowicz-Jones EV, Brazel AJ, Frigenti F, Urbé S, Clague MJ.
PMID: 34895815
Semin Cell Dev Biol. 2021 Dec 08; doi: 10.1016/j.semcdb.2021.11.016. Epub 2021 Dec 08.

We now have a comprehensive inventory of ubiquitin system components. Understanding of any system also needs an appreciation of how components are organised together. Quantitative proteomics has provided us with a census of their relative populations in several model...

Benchmarking a highly selective USP30 inhibitor for enhancement of mitophagy and pexophagy.

Life science alliance

Rusilowicz-Jones EV, Barone FG, Lopes FM, Stephen E, Mortiboys H, Urbé S, Clague MJ.
PMID: 34844982
Life Sci Alliance. 2021 Nov 29;5(2). doi: 10.26508/lsa.202101287. Print 2022 Feb.

The deubiquitylase USP30 is an actionable target considered for treatment of conditions associated with defects in the PINK1-PRKN pathway leading to mitophagy. We provide a detailed cell biological characterization of a benzosulphonamide molecule, compound 39, that has previously been...

Redox Chemistry and the Role of Trapped Molecular O.

Journal of the American Chemical Society

Sharpe R, House RA, Clarke MJ, Förstermann D, Marie JJ, Cibin G, Zhou KJ, Playford HY, Bruce PG, Islam MS.
PMID: 33321041
J Am Chem Soc. 2020 Dec 30;142(52):21799-21809. doi: 10.1021/jacs.0c10270. Epub 2020 Dec 15.

In the search for high energy density cathodes for next-generation lithium-ion batteries, the disordered rocksalt oxyfluorides are receiving significant attention due to their high capacity and lower voltage hysteresis compared with ordered Li-rich layered compounds. However, a deep understanding...

Trends in U.S. Insulin Use and Glucose Monitoring for People with Diabetes: 2009-2018.

Journal of diabetes science and technology

Perez-Nieves M, Juneja R, Fan L, Meadows E, Lage MJ, Eby EL.
PMID: 34218716
J Diabetes Sci Technol. 2021 Jul 05;19322968211028268. doi: 10.1177/19322968211028268. Epub 2021 Jul 05.

BACKGROUND: The delivery and administration of insulin has undergone many changes over the years. This research examines U.S. trends in insulin use among people with type 1 diabetes (T1D) or type 2 diabetes (T2D) in the U.S. from 2009...

Teaching about Health Disparities: Pedagogy, Curriculum, and Learning Theory.

The American journal of bioethics : AJOB

Clarke MJ, Laughlin-Tommaso S, Seegmiller Renner A.
PMID: 34399675
Am J Bioeth. 2021 Sep;21(9):18-20. doi: 10.1080/15265161.2021.1952340.

No abstract available.

Time to Failure on Oral Glucose-Lowering Agents for Patients with Type 2 Diabetes: A Retrospective Cohort Study.

Diabetes therapy : research, treatment and education of diabetes and related disorders

Boye KS, Lage MJ, Kiljański J.
PMID: 33837921
Diabetes Ther. 2021 May;12(5):1463-1474. doi: 10.1007/s13300-021-01051-9. Epub 2021 Apr 10.

INTRODUCTION: Research has shown that glycemic control is associated with lower rates of microvascular and long-term cardiovascular complications. In the analyses reported here, we examined treatment failure on oral glucose-lowering agents (GLAs), defined as having sustained hemoglobin A1c (HbA1c)...

Showing 109 to 115 of 115 entries