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Showing 961 to 969 of 969 entries
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Prognostic Significance of Blood-Based Multi-cancer Detection in Plasma Cell-Free DNA.

Clinical cancer research : an official journal of the American Association for Cancer Research

Chen X, Dong Z, Hubbell E, Kurtzman KN, Oxnard GR, Venn O, Melton C, Clarke CA, Shaknovich R, Ma T, Meixiong G, Seiden MV, Klein EA, Fung ET, Liu MC.
PMID: 34088722
Clin Cancer Res. 2021 Aug 01;27(15):4221-4229. doi: 10.1158/1078-0432.CCR-21-0417. Epub 2021 Jun 04.

PURPOSE: We recently reported the development of a cell-free DNA (cfDNA) targeted methylation (TM)-based sequencing approach for a multi-cancer early detection (MCED) test that includes cancer signal origin prediction. Here, we evaluated the prognostic significance of cancer detection by...

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Chen X, Dong Z, Hubbell E, et al. Prognostic Significance of Blood-Based Multi-cancer Detection in Plasma Cell-Free DNA. Clin Cancer Res. 2021;27(15):4221-4229doi: 10.1158/1078-0432.CCR-21-0417.
Chen, X., Dong, Z., Hubbell, E., Kurtzman, K. N., Oxnard, G. R., Venn, O., Melton, C., Clarke, C. A., Shaknovich, R., Ma, T., Meixiong, G., Seiden, M. V., Klein, E. A., Fung, E. T., & Liu, M. C. (2021). Prognostic Significance of Blood-Based Multi-cancer Detection in Plasma Cell-Free DNA. Clinical cancer research : an official journal of the American Association for Cancer Research, 27(15), 4221-4229. https://doi.org/10.1158/1078-0432.CCR-21-0417
Chen, Xiaoji, et al. "Prognostic Significance of Blood-Based Multi-cancer Detection in Plasma Cell-Free DNA." Clinical cancer research : an official journal of the American Association for Cancer Research vol. 27,15 (2021): 4221-4229. doi: https://doi.org/10.1158/1078-0432.CCR-21-0417
Chen X, Dong Z, Hubbell E, Kurtzman KN, Oxnard GR, Venn O, Melton C, Clarke CA, Shaknovich R, Ma T, Meixiong G, Seiden MV, Klein EA, Fung ET, Liu MC. Prognostic Significance of Blood-Based Multi-cancer Detection in Plasma Cell-Free DNA. Clin Cancer Res. 2021 Aug 01;27(15):4221-4229. doi: 10.1158/1078-0432.CCR-21-0417. Epub 2021 Jun 04. PMID: 34088722.
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Goblet Cell Hyperplasia is not Epithelial-Autonomous in the Cftr Knockout Intestine.

American journal of physiology. Gastrointestinal and liver physiology

Walker NM, Liu J, Young SM, Woode RA, Clarke LL.
PMID: 34878935
Am J Physiol Gastrointest Liver Physiol. 2021 Dec 08; doi: 10.1152/ajpgi.00290.2021. Epub 2021 Dec 08.

Goblet cell hyperplasia is an important manifestation of cystic fibrosis (CF) disease in epithelial-lined organs. Explants of CF airway epithelium show normalization of goblet cell numbers; therefore we hypothesized that small intestinal enteroids from Cftr knockout (KO) mice would...

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Walker NM, Liu J, Young SM, et al. Goblet Cell Hyperplasia is not Epithelial-Autonomous in the Cftr Knockout Intestine. Am J Physiol Gastrointest Liver Physiol. 2021;doi: 10.1152/ajpgi.00290.2021.
Walker, N. M., Liu, J., Young, S. M., Woode, R. A., & Clarke, L. L. (2021). Goblet Cell Hyperplasia is not Epithelial-Autonomous in the Cftr Knockout Intestine. American journal of physiology. Gastrointestinal and liver physiology, . https://doi.org/10.1152/ajpgi.00290.2021
Walker, Nancy M, et al. "Goblet Cell Hyperplasia is not Epithelial-Autonomous in the Cftr Knockout Intestine." American journal of physiology. Gastrointestinal and liver physiology vol. (2021). doi: https://doi.org/10.1152/ajpgi.00290.2021
Walker NM, Liu J, Young SM, Woode RA, Clarke LL. Goblet Cell Hyperplasia is not Epithelial-Autonomous in the Cftr Knockout Intestine. Am J Physiol Gastrointest Liver Physiol. 2021 Dec 08; doi: 10.1152/ajpgi.00290.2021. Epub 2021 Dec 08. PMID: 34878935.
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Validation of the SCAT5 and Child SCAT5 Word-List Memory Task.

Journal of neurotrauma

Shapiro JS, Hearps S, Rausa VC, Anderson V, Anderson N, Pugh R, Chau T, Clarke C, Davis GA, Fabiano F, Fan F, Parkin GM, Takagi M, Babl FE.
PMID: 33765839
J Neurotrauma. 2021 May 10; doi: 10.1089/neu.2020.7414. Epub 2021 May 10.

The Sports Concussion Assessment Tool-5th Edition (SCAT5) and the child version (Child SCAT5) are the current editions of the SCAT and have updated the memory testing component from previous editions. This study aimed to validate this new memory component...

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Shapiro JS, Hearps S, Rausa VC, et al. Validation of the SCAT5 and Child SCAT5 Word-List Memory Task. J Neurotrauma. 2021;doi: 10.1089/neu.2020.7414.
Shapiro, J. S., Hearps, S., Rausa, V. C., Anderson, V., Anderson, N., Pugh, R., Chau, T., Clarke, C., Davis, G. A., Fabiano, F., Fan, F., Parkin, G. M., Takagi, M., & Babl, F. E. (2021). Validation of the SCAT5 and Child SCAT5 Word-List Memory Task. Journal of neurotrauma, . https://doi.org/10.1089/neu.2020.7414
Shapiro, Jesse S, et al. "Validation of the SCAT5 and Child SCAT5 Word-List Memory Task." Journal of neurotrauma vol. (2021). doi: https://doi.org/10.1089/neu.2020.7414
Shapiro JS, Hearps S, Rausa VC, Anderson V, Anderson N, Pugh R, Chau T, Clarke C, Davis GA, Fabiano F, Fan F, Parkin GM, Takagi M, Babl FE. Validation of the SCAT5 and Child SCAT5 Word-List Memory Task. J Neurotrauma. 2021 May 10; doi: 10.1089/neu.2020.7414. Epub 2021 May 10. PMID: 33765839.
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Prognostic Significance of Preoperative Tumor Markers in Pseudomyxoma Peritonei from Low-Grade Appendiceal Mucinous Neoplasm: a Study from the US HIPEC Collaborative.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

Nizam W, Fackche N, Pessoa B, Kubi B, Cloyd JM, Grotz T, Fournier K, Dineen S, Veerapong J, Baumgartner JM, Clarke C, Patel SH, Wilson GC, Lambert L, Abbott DE, Vande Walle KA, Lee B, Raoof M, Maithel SK, Russell MC, Zaidi MY, Johnston FM, Greer JB.
PMID: 34506026
J Gastrointest Surg. 2021 Sep 10; doi: 10.1007/s11605-021-05075-1. Epub 2021 Sep 10.

BACKGROUND: Tumor markers are commonly utilized in the diagnostic evaluation, treatment decision making, and surveillance of appendiceal tumors. In this study, we aimed to determine the prognostic significance of elevated preoperative tumor markers in patients with pseudomyxoma peritonei secondary...

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Nizam W, Fackche N, Pessoa B, et al. Prognostic Significance of Preoperative Tumor Markers in Pseudomyxoma Peritonei from Low-Grade Appendiceal Mucinous Neoplasm: a Study from the US HIPEC Collaborative. J Gastrointest Surg. 2021;doi: 10.1007/s11605-021-05075-1.
Nizam, W., Fackche, N., Pessoa, B., Kubi, B., Cloyd, J. M., Grotz, T., Fournier, K., Dineen, S., Veerapong, J., Baumgartner, J. M., Clarke, C., Patel, S. H., Wilson, G. C., Lambert, L., Abbott, D. E., Vande Walle, K. A., Lee, B., Raoof, M., Maithel, S. K., Russell, M. C., Zaidi, M. Y., Johnston, F. M., & Greer, J. B. (2021). Prognostic Significance of Preoperative Tumor Markers in Pseudomyxoma Peritonei from Low-Grade Appendiceal Mucinous Neoplasm: a Study from the US HIPEC Collaborative. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, . https://doi.org/10.1007/s11605-021-05075-1
Nizam, Wasay, et al. "Prognostic Significance of Preoperative Tumor Markers in Pseudomyxoma Peritonei from Low-Grade Appendiceal Mucinous Neoplasm: a Study from the US HIPEC Collaborative." Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract vol. (2021). doi: https://doi.org/10.1007/s11605-021-05075-1
Nizam W, Fackche N, Pessoa B, Kubi B, Cloyd JM, Grotz T, Fournier K, Dineen S, Veerapong J, Baumgartner JM, Clarke C, Patel SH, Wilson GC, Lambert L, Abbott DE, Vande Walle KA, Lee B, Raoof M, Maithel SK, Russell MC, Zaidi MY, Johnston FM, Greer JB. Prognostic Significance of Preoperative Tumor Markers in Pseudomyxoma Peritonei from Low-Grade Appendiceal Mucinous Neoplasm: a Study from the US HIPEC Collaborative. J Gastrointest Surg. 2021 Sep 10; doi: 10.1007/s11605-021-05075-1. Epub 2021 Sep 10. PMID: 34506026.
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Randomized Phase II and Biomarker Study of Pembrolizumab plus Bevacizumab versus Pembrolizumab Alone for Patients with Recurrent Glioblastoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Nayak L, Molinaro AM, Peters K, Clarke JL, Jordan JT, de Groot J, Nghiemphu L, Kaley T, Colman H, McCluskey C, Gaffey S, Smith TR, Cote DJ, Severgnini M, Yearley JH, Zhao Q, Blumenschein WM, Duda DG, Muzikansky A, Jain RK, Wen PY, Reardon DA.
PMID: 33199490
Clin Cancer Res. 2021 Feb 15;27(4):1048-1057. doi: 10.1158/1078-0432.CCR-20-2500. Epub 2020 Nov 16.

PURPOSE: VEGF is upregulated in glioblastoma and may contribute to immunosuppression. We performed a phase II study of pembrolizumab alone or with bevacizumab in recurrent glioblastoma.PATIENTS AND METHODS: Eighty bevacizumab-naïve patients with recurrent glioblastoma were randomized to pembrolizumab with...

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Nayak L, Molinaro AM, Peters K, et al. Randomized Phase II and Biomarker Study of Pembrolizumab plus Bevacizumab versus Pembrolizumab Alone for Patients with Recurrent Glioblastoma. Clin Cancer Res. 2020;27(4):1048-1057doi: 10.1158/1078-0432.CCR-20-2500.
Nayak, L., Molinaro, A. M., Peters, K., Clarke, J. L., Jordan, J. T., de Groot, J., Nghiemphu, L., Kaley, T., Colman, H., McCluskey, C., Gaffey, S., Smith, T. R., Cote, D. J., Severgnini, M., Yearley, J. H., Zhao, Q., Blumenschein, W. M., Duda, D. G., Muzikansky, A., Jain, R. K., Wen, P. Y., & Reardon, D. A. (2021). Randomized Phase II and Biomarker Study of Pembrolizumab plus Bevacizumab versus Pembrolizumab Alone for Patients with Recurrent Glioblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research, 27(4), 1048-1057. https://doi.org/10.1158/1078-0432.CCR-20-2500
Nayak, Lakshmi, et al. "Randomized Phase II and Biomarker Study of Pembrolizumab plus Bevacizumab versus Pembrolizumab Alone for Patients with Recurrent Glioblastoma." Clinical cancer research : an official journal of the American Association for Cancer Research vol. 27,4 (2021): 1048-1057. doi: https://doi.org/10.1158/1078-0432.CCR-20-2500
Nayak L, Molinaro AM, Peters K, Clarke JL, Jordan JT, de Groot J, Nghiemphu L, Kaley T, Colman H, McCluskey C, Gaffey S, Smith TR, Cote DJ, Severgnini M, Yearley JH, Zhao Q, Blumenschein WM, Duda DG, Muzikansky A, Jain RK, Wen PY, Reardon DA. Randomized Phase II and Biomarker Study of Pembrolizumab plus Bevacizumab versus Pembrolizumab Alone for Patients with Recurrent Glioblastoma. Clin Cancer Res. 2021 Feb 15;27(4):1048-1057. doi: 10.1158/1078-0432.CCR-20-2500. Epub 2020 Nov 16. PMID: 33199490; PMCID: PMC8284901.
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Inhibition of miR-99a-5p prevents allergen-driven airway exacerbations without compromising type-2 memory responses in the intestine following helminth infection.

Mucosal immunology

Entwistle L, Aegerter H, Czieso S, Amaniti E, Guidi R, Sesay A, Nikolov N, Chakravaty P, Huynh A, Mills J, Flanagan S, Hambro S, Nunez V, Cao Y, Clarke C, Martzall A, Leong L, Wilson D, Austin C, Wilson M.
PMID: 33846533
Mucosal Immunol. 2021 Jul;14(4):912-922. doi: 10.1038/s41385-021-00401-x. Epub 2021 Apr 12.

Acute exacerbations (AE) of asthma, remain one of the biggest concerns for patients living with asthma. As such, identifying the causes, the molecular mechanisms involved and new therapeutic interventions to prevent AE is a high priority. Immunity to intestinal...

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Entwistle L, Aegerter H, Czieso S, et al. Inhibition of miR-99a-5p prevents allergen-driven airway exacerbations without compromising type-2 memory responses in the intestine following helminth infection. Mucosal Immunol. 2021;14(4):912-922doi: 10.1038/s41385-021-00401-x.
Entwistle, L., Aegerter, H., Czieso, S., Amaniti, E., Guidi, R., Sesay, A., Nikolov, N., Chakravaty, P., Huynh, A., Mills, J., Flanagan, S., Hambro, S., Nunez, V., Cao, Y., Clarke, C., Martzall, A., Leong, L., Wilson, D., Austin, C., & Wilson, M. (2021). Inhibition of miR-99a-5p prevents allergen-driven airway exacerbations without compromising type-2 memory responses in the intestine following helminth infection. Mucosal immunology, 14(4), 912-922. https://doi.org/10.1038/s41385-021-00401-x
Entwistle, Lewis, et al. "Inhibition of miR-99a-5p prevents allergen-driven airway exacerbations without compromising type-2 memory responses in the intestine following helminth infection." Mucosal immunology vol. 14,4 (2021): 912-922. doi: https://doi.org/10.1038/s41385-021-00401-x
Entwistle L, Aegerter H, Czieso S, Amaniti E, Guidi R, Sesay A, Nikolov N, Chakravaty P, Huynh A, Mills J, Flanagan S, Hambro S, Nunez V, Cao Y, Clarke C, Martzall A, Leong L, Wilson D, Austin C, Wilson M. Inhibition of miR-99a-5p prevents allergen-driven airway exacerbations without compromising type-2 memory responses in the intestine following helminth infection. Mucosal Immunol. 2021 Jul;14(4):912-922. doi: 10.1038/s41385-021-00401-x. Epub 2021 Apr 12. PMID: 33846533; PMCID: PMC8222002.
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Plant-Produced Vaccines: Future Applications in Aquaculture.

Frontiers in plant science

Su H, Yakovlev IA, van Eerde A, Su J, Clarke JL.
PMID: 34456958
Front Plant Sci. 2021 Aug 12;12:718775. doi: 10.3389/fpls.2021.718775. eCollection 2021.

Aquaculture has undergone rapid development in the past decades. It provides a large part of high-quality protein food for humans, and thus, a sustainable aquaculture industry is of great importance for the worldwide food supply and economy. Along with...

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Su H, Yakovlev IA, van Eerde A, et al. Plant-Produced Vaccines: Future Applications in Aquaculture. Front Plant Sci. 2021;12:718775doi: 10.3389/fpls.2021.718775.
Su, H., Yakovlev, I. A., van Eerde, A., Su, J., & Clarke, J. L. (2021). Plant-Produced Vaccines: Future Applications in Aquaculture. Frontiers in plant science, 12718775. https://doi.org/10.3389/fpls.2021.718775
Su, Hang, et al. "Plant-Produced Vaccines: Future Applications in Aquaculture." Frontiers in plant science vol. 12 (2021): 718775. doi: https://doi.org/10.3389/fpls.2021.718775
Su H, Yakovlev IA, van Eerde A, Su J, Clarke JL. Plant-Produced Vaccines: Future Applications in Aquaculture. Front Plant Sci. 2021 Aug 12;12:718775. doi: 10.3389/fpls.2021.718775. eCollection 2021. PMID: 34456958; PMCID: PMC8397579.
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Broadening Participation in Computing: K12-Community-College-University-Graduate Pathways.

Ieee, Biskup S, Clarke L, Adrion WR, Boisvert D, Fountain J, Grocer P, Mackler S, Peterfreund AR, Rath KA, Smith A, Snyder DD, Wiens A.
UIID-AD: 859
2008;1742-1747.

The Commonwealth Alliance for Information Technology Education (CAITE) is designing and carrying out comprehensive programs that address under-representation in information technology (IT). CAITE focuses on women and minorities in groups that are underrepresented in most aspects of the Massachusetts...

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Ieee, Biskup S, Clarke L, et al. Broadening Participation in Computing: K12-Community-College-University-Graduate Pathways. 2008;1742-1747
Ieee, Biskup, S., Clarke, L., Adrion, W. R., Boisvert, D., Fountain, J., Grocer, P., Mackler, S., Peterfreund, A. R., Rath, K. A., Smith, A., Snyder, D. D., & Wiens, A. (2008). Broadening Participation in Computing: K12-Community-College-University-Graduate Pathways. 1742-1747.
Ieee, et al. "Broadening Participation in Computing: K12-Community-College-University-Graduate Pathways." vol. (2008): 1742-1747.
Ieee, Biskup S, Clarke L, Adrion WR, Boisvert D, Fountain J, Grocer P, Mackler S, Peterfreund AR, Rath KA, Smith A, Snyder DD, Wiens A. Broadening Participation in Computing: K12-Community-College-University-Graduate Pathways. 2008;1742-1747. UIID-AD: 859.
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The functional spectrum of low-frequency coding variation.

Marth GT, Yu FL, Indap AR, Garimella K, Gravel S, Leong WF, Tyler-Smith C, Bainbridge M, Blackwell T, Zheng-Bradley X, Chen Y, Challis D, Clarke L, Ball EV, Cibulskis K, Cooper DN, Fulton B, Hartl C, Koboldt D, Muzny D, Smith R, Sougnez C, Stewart C, Ward A, Yu J, Xue YL, Altshuler D, Bustamante CD, Clark AG, Daly M, DePristo M, Flicek P, Gabriel S, Mardis E, Palotie A, Gibbs R, Genomes Project.
UIID-AD: 715
2011;12. doi: 10.1186/gb-2011-12-9-r84.

Background: Rare coding variants constitute an important class of human genetic variation, but are underrepresented in current databases that are based on small population samples. Recent studies show that variants altering amino acid sequence and protein function are enriched...

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Marth GT, Yu FL, Indap AR, et al. The functional spectrum of low-frequency coding variation. 2011;12doi: 10.1186/gb-2011-12-9-r84.
Marth, G. T., Yu, F. L., Indap, A. R., Garimella, K., Gravel, S., Leong, W. F., Tyler-Smith, C., Bainbridge, M., Blackwell, T., Zheng-Bradley, X., Chen, Y., Challis, D., Clarke, L., Ball, E. V., Cibulskis, K., Cooper, D. N., Fulton, B., Hartl, C., Koboldt, D., Muzny, D., Smith, R., Sougnez, C., Stewart, C., Ward, A., Yu, J., Xue, Y. L., Altshuler, D., Bustamante, C. D., Clark, A. G., Daly, M., DePristo, M., Flicek, P., Gabriel, S., Mardis, E., Palotie, A., Gibbs, R., & Genomes, P. r. o. j. e. c. t. (2011). The functional spectrum of low-frequency coding variation. 12. https://doi.org/10.1186/gb-2011-12-9-r84
Marth, G T, et al. "The functional spectrum of low-frequency coding variation." vol. 12 (2011). doi: https://doi.org/10.1186/gb-2011-12-9-r84
Marth GT, Yu FL, Indap AR, Garimella K, Gravel S, Leong WF, Tyler-Smith C, Bainbridge M, Blackwell T, Zheng-Bradley X, Chen Y, Challis D, Clarke L, Ball EV, Cibulskis K, Cooper DN, Fulton B, Hartl C, Koboldt D, Muzny D, Smith R, Sougnez C, Stewart C, Ward A, Yu J, Xue YL, Altshuler D, Bustamante CD, Clark AG, Daly M, DePristo M, Flicek P, Gabriel S, Mardis E, Palotie A, Gibbs R, Genomes Project. The functional spectrum of low-frequency coding variation. 2011;12. doi: 10.1186/gb-2011-12-9-r84. UIID-AD: 715.
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Showing 961 to 969 of 969 entries