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Showing 13 to 24 of 85 entries
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Synthesis of Tailored Perfluoro Unsaturated Monomers for Potential Applications in Proton Exchange Membrane Preparation.

Molecules (Basel, Switzerland)

Monopoli A, Casiello M, Cotugno P, Milella A, Palumbo F, Fracassi F, Nacci A.
PMID: 34577063
Molecules. 2021 Sep 15;26(18). doi: 10.3390/molecules26185592.

The aim of the present work is the synthesis and characterization of new perfluorinated monomers bearing, similarly to Nafion

Randomized Phase II Trial of Sipuleucel-T with or without Radium-223 in Men with Bone-metastatic Castration-resistant Prostate Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Marshall CH, Fu W, Wang H, Park JC, DeWeese TL, Tran PT, Song DY, King S, Afful M, Hurrelbrink J, Manogue C, Cotogno P, Moldawer NP, Barata PC, Drake CG, Posadas EM, Armstrong AJ, Sartor O, Antonarakis ES.
PMID: 33451978
Clin Cancer Res. 2021 Mar 15;27(6):1623-1630. doi: 10.1158/1078-0432.CCR-20-4476. Epub 2021 Jan 15.

PURPOSE: To investigate whether radium-223 increases peripheral immune responses to sipuleucel-T in men with bone-predominant, minimally symptomatic metastatic castration-resistant prostate cancer (mCRPC).PATIENTS AND METHODS: A total of 32 patients were randomized 1:1 in this open-label, phase II multicenter trial....

Disruption of the Phosphate Transporter Pit1 in Hepatocytes Improves Glucose Metabolism and Insulin Signaling by Modulating the USP7/IRS1 Interaction.

Cell reports

Forand A, Koumakis E, Rousseau A, Sassier Y, Journe C, Merlin JF, Leroy C, Boitez V, Codogno P, Friedlander G, Cohen I.
PMID: 27829160
Cell Rep. 2016 Nov 08;17(7):1905. doi: 10.1016/j.celrep.2016.10.039.

No abstract available.

Activated Carbon from Palm Date Seeds for CO.

International journal of environmental research and public health

Alazmi A, Nicolae SA, Modugno P, Hasanov BE, Titirici MM, Costa PMFJ.
PMID: 34831898
Int J Environ Res Public Health. 2021 Nov 19;18(22). doi: 10.3390/ijerph182212142.

The process of carbon dioxide capture and storage is seen as a critical strategy to mitigate the so-called greenhouse effect and the planetary climate changes associated with it. In this study, we investigated the CO

ATG4D is the main ATG8 delipidating enzyme in mammalian cells and protects against cerebellar neurodegeneration.

Cell death and differentiation

Tamargo-Gómez I, Martínez-García GG, Suárez MF, Rey V, Fueyo A, Codina-Martínez H, Bretones G, Caravia XM, Morel E, Dupont N, Cabo R, Tomás-Zapico C, Souquere S, Pierron G, Codogno P, López-Otín C, Fernández ÁF, Mariño G.
PMID: 33795848
Cell Death Differ. 2021 Sep;28(9):2651-2672. doi: 10.1038/s41418-021-00776-1. Epub 2021 Apr 01.

Despite the great advances in autophagy research in the last years, the specific functions of the four mammalian Atg4 proteases (ATG4A-D) remain unclear. In yeast, Atg4 mediates both Atg8 proteolytic activation, and its delipidation. However, it is not clear...

Incidence and risk factors for potentially suboptimal serum concentrations of vancomycin during cardiac surgery.

World journal of cardiology

Cotogni P, Barbero C, Rinaldi M.
PMID: 30510640
World J Cardiol. 2018 Nov 26;10(11):234-241. doi: 10.4330/wjc.v10.i11.234.

AIM: To investigate the incidence and risk factors for vancomycin concentrations less than 10 mg/L during cardiac surgery.METHODS: In this prospective study, patients undergoing cardiac surgery received a single dose of 1000 mg of vancomycin. Multiple arterial samples were...

The Advantages of Clinical Nutrition Use in Oncologic Patients in Italy: Real World Insights.

Healthcare (Basel, Switzerland)

Pedrazzoli P, Caccialanza R, Cotogni P, Degli Esposti L, Perrone V, Sangiorgi D, Di Costanzo F, Gavazzi C, Santoro A, Pinto C.
PMID: 32384639
Healthcare (Basel). 2020 May 06;8(2). doi: 10.3390/healthcare8020125.

This retrospective observational study aimed to provide insights on the use of clinical nutrition (CN) (enteral and parenteral feeding) and outcomes in an Italian real-world setting. The data source comes from administrative databases of 10 Italian Local Health Units....

In-Hospital Palliative Care: Should We Need to Reconsider What Role Hospitals Should Have in Patients with End-Stage Disease or Advanced Cancer?.

Journal of clinical medicine

Cotogni P, Saini A, De Luca A.
PMID: 29385757
J Clin Med. 2018 Jan 30;7(2). doi: 10.3390/jcm7020018.

Traditionally, palliative care (PC) systems focused on the needs of advanced cancer patients, but most patients needing PC have end-stage organ diseases. Similarly, PC models focus on the needs of patients in hospices or at home; however, in most...

ER-driven membrane contact sites: Evolutionary conserved machineries for stress response and autophagy regulation?.

Communicative & integrative biology

Molino D, Nascimbeni AC, Giordano F, Codogno P, Morel E.
PMID: 29259731
Commun Integr Biol. 2017 Dec 13;10(5):e1401699. doi: 10.1080/19420889.2017.1401699. eCollection 2017.

Endoplasmic Reticulum (ER), spreading in the whole cell cytoplasm, is a central player in eukaryotic cell homeostasis, from plants to mammals. Beside crucial functions, such as membrane lipids and proteins synthesis and outward transport, the ER is able to...

Autophagosomal membranes assemble at ER-plasma membrane contact sites.

Molecular & cellular oncology

Nascimbeni AC, Codogno P, Morel E.
PMID: 29057312
Mol Cell Oncol. 2017 Jul 25;4(5):e1356431. doi: 10.1080/23723556.2017.1356431. eCollection 2017.

The biogenesis of autophagosome, the double membrane bound organelle related to macro-autophagy, is a complex event requiring numerous key-proteins and membrane remodeling events. Our recent findings identify the extended synaptotagmins, crucial tethers of Endoplasmic Reticulum-plasma membrane contact sites, as...

Chronic consumption of fructose rich soft drinks alters tissue lipids of rats.

Diabetology & metabolic syndrome

Botezelli JD, Dalia RA, Reis IM, Barbieri RA, Rezende TM, Pelarigo JG, Codogno J, Gonçalves R, Mello MA.
PMID: 20573247
Diabetol Metab Syndr. 2010 Jun 23;2:43. doi: 10.1186/1758-5996-2-43.

BACKGROUND: Fructose-based diets are apparently related to the occurrence of several metabolic dysfunctions, but the effects of the consumption of high amounts of fructose on body tissues have not been well described. The aim of this study was to...

Heck reactions with palladium nanoparticles in ionic liquids: coupling of aryl chlorides with deactivated olefins.

Angewandte Chemie (International ed. in English)

Calò V, Nacci A, Monopoli A, Cotugno P.
PMID: 19603441
Angew Chem Int Ed Engl. 2009;48(33):6101-3. doi: 10.1002/anie.200902337.

No abstract available.

Showing 13 to 24 of 85 entries