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Showing 49 to 56 of 56 entries
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Impact of intracoronary optical coherence tomography in routine clinical practice: A contemporary cohort study.

Cardiovascular revascularization medicine : including molecular interventions

Häner JD, Duband B, Ueki Y, Otsuka T, Combaret N, Siontis GCM, Bär S, Stortecky S, Motreff P, Losdat S, Windecker S, Souteyrand G, Räber L.
PMID: 34340915
Cardiovasc Revasc Med. 2021 Jul 27; doi: 10.1016/j.carrev.2021.07.024. Epub 2021 Jul 27.

BACKGROUND/PURPOSE: Guidelines recommend intracoronary optical coherence tomography (OCT) to assess stent failure and guide percutaneous coronary intervention (PCI) but OCT may be useful for other indications in routine clinical practice.METHODS/MATERIALS: We conducted an international registry of OCT cases at...

Oxygen uptake kinetics during treadmill walking in adolescents with clinically stable cystic fibrosis.

Physiotherapy theory and practice

Combret Y, Medrinal C, Prieur G, Robledo Quesada A, Gillot T, Gravier FE, Bonnevie T, Lamia B, Le Roux P, Reychler G.
PMID: 33390080
Physiother Theory Pract. 2021 Jan 04;1-9. doi: 10.1080/09593985.2020.1868029. Epub 2021 Jan 04.

No abstract available.

Prehabilitation sessions can be provided more frequently in a shortened regimen with similar or better efficacy in people with non-small cell lung cancer: a randomised trial.

Journal of physiotherapy

Gravier FE, Smondack P, Boujibar F, Prieur G, Medrinal C, Combret Y, Muir JF, Baste JM, Cuvelier A, Debeaumont D, Bonnevie T.
PMID: 34952813
J Physiother. 2022 Jan;68(1):43-50. doi: 10.1016/j.jphys.2021.12.010. Epub 2021 Dec 21.

QUESTION: In people with non-small cell lung cancer, what is the effect of condensing 15 prehabilitation sessions into a 3-week regimen compared with a 5-week regimen?DESIGN: Randomised controlled trial with concealed allocation, intention-to-treat analysis and blinded assessment of the...

Association of cabozantinib pharmacokinetics, progression and toxicity in metastatic renal cell carcinoma patients: results from a pharmacokinetics/pharmacodynamics study.

ESMO open

Cerbone L, Combarel D, Geraud A, Auclin E, Foulon S, Alves Costa Silva C, Colomba E, Carril L, Derosa L, Flippot R, Mir O, Khoudour N, Blanchet B, Escudier B, Paci A, Albiges L.
PMID: 34864351
ESMO Open. 2021 Dec 01;6(6):100312. doi: 10.1016/j.esmoop.2021.100312. Epub 2021 Dec 01.

BACKGROUND: Cabozantinib is a tyrosine kinase inhibitor with a substantial efficacy in metastatic renal cell carcinoma, and is associated with a challenging toxicity profile leading to frequent drug discontinuations. Whereas an exposure/safety relationship was demonstrated for this drug, an...

Targeted Therapy of .

Clinical cancer research : an official journal of the American Association for Cancer Research

Chen J, Nelson C, Wong M, Tee AE, Liu PY, La T, Fletcher JI, Kamili A, Mayoh C, Bartenhagen C, Trahair TN, Xu N, Jayatilleke N, Wong M, Peng H, Atmadibrata B, Cheung BB, Lan Q, Bryan TM, Mestdagh P, Vandesompele J, Combaret V, Boeva V, Wang JY, Janoueix-Lerosey I, Cowley MJ, MacKenzie KL, Dolnikov A, Li J, Polly P, Marshall GM, Reddel RR, Norris MD, Haber M, Fischer M, Zhang XD, Pickett HA, Liu T.
PMID: 33310889
Clin Cancer Res. 2021 Mar 01;27(5):1438-1451. doi: 10.1158/1078-0432.CCR-20-3044. Epub 2020 Dec 11.

EXPERIMENTAL DESIGN: Anticancer agents exerting the best synergistic anticancer effects with BET bromodomain inhibitors were identified by screening an FDA-approved oncology drug library. The synergistic effects of the BET bromodomain inhibitor OTX015 and the proteasome inhibitor carfilzomib were examined...

Frequency and Prognostic Impact of .

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Bellini A, Pötschger U, Bernard V, Lapouble E, Baulande S, Ambros PF, Auger N, Beiske K, Bernkopf M, Betts DR, Bhalshankar J, Bown N, de Preter K, Clément N, Combaret V, Font de Mora J, George SL, Jiménez I, Jeison M, Marques B, Martinsson T, Mazzocco K, Morini M, Mühlethaler-Mottet A, Noguera R, Pierron G, Rossing M, Taschner-Mandl S, Van Roy N, Vicha A, Chesler L, Balwierz W, Castel V, Elliott M, Kogner P, Laureys G, Luksch R, Malis J, Popovic-Beck M, Ash S, Delattre O, Valteau-Couanet D, Tweddle DA, Ladenstein R, Schleiermacher G.
PMID: 34115544
J Clin Oncol. 2021 Oct 20;39(30):3377-3390. doi: 10.1200/JCO.21.00086. Epub 2021 Jun 11.

PURPOSE: In neuroblastoma (NB), the ALK receptor tyrosine kinase can be constitutively activated through activating point mutations or genomic amplification. We studied MATERIALS AND METHODS: Diagnostic tumor samples were available from 1,092 HR-NBL1/SIOPEN patients to determine RESULTS: Genomic CONCLUSION:...

[Contribution of optical coherence tomography in the management of intrastent restenosis].

Annales de cardiologie et d'angeiologie

Mouyen T, Combaret N, Souteyrand G.
PMID: 34756601
Ann Cardiol Angeiol (Paris). 2021 Dec;70(6):451-456. doi: 10.1016/j.ancard.2021.10.010. Epub 2021 Oct 29.

Intrastent restenosis (ISR) remains a common problem in interventional cardiology. Angiographic data are limited in assessing ISR. Optical coherence tomography (OCT) is a high-resolution endocoronary imaging technique. It allows individualization of the stent struts and thus reveals stent under-expansion...

Chronic Plasma Exposure to Kinase Inhibitors in Patients with Oncogene-Addicted Non-Small Cell Lung Cancer.

Cancers

Geraud A, Mezquita L, Auclin E, Combarel D, Delahousse J, Gougis P, Massard C, Jovelet C, Caramella C, Adam J, Naltet C, Lavaud P, Gazzah A, Lacroix L, Rouleau E, Vasseur D, Mir O, Planchard D, Paci A, Besse B.
PMID: 33327482
Cancers (Basel). 2020 Dec 14;12(12). doi: 10.3390/cancers12123758.

Kinase inhibitors (KI) have dramatically improved the outcome of treatment in patients with non-small cell lung cancer (NSCLC), which harbors an oncogene addiction. This study assesses KI plasma levels and their clinical relevance in patients chronically exposed to KIs....

Showing 49 to 56 of 56 entries