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Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing.

Neurobiology of disease

Raposo M, Bettencourt C, Melo ARV, Ferreira AF, Alonso I, Silva P, Vasconcelos J, Kay T, Saraiva-Pereira ML, Costa MD, Vilasboas-Campos D, Bettencourt BF, Bruges-Armas J, Houlden H, Heutink P, Jardim LB, Sequeiros J, Maciel P, Lima M.
PMID: 34871736
Neurobiol Dis. 2021 Dec 03;162:105578. doi: 10.1016/j.nbd.2021.105578. Epub 2021 Dec 03.

Machado-Joseph disease (MJD/SCA3) is a neurodegenerative polyglutamine disorder exhibiting a wide spectrum of phenotypes. The abnormal size of the (CAG)n at ATXN3 explains ~55% of the age at onset variance, suggesting the involvement of other factors, namely genetic modifiers,...

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Raposo M, Bettencourt C, Melo ARV, et al. Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing. Neurobiol Dis. 2021;162:105578doi: 10.1016/j.nbd.2021.105578.
Raposo, M., Bettencourt, C., Melo, A. R. V., Ferreira, A. F., Alonso, I., Silva, P., Vasconcelos, J., Kay, T., Saraiva-Pereira, M. L., Costa, M. D., Vilasboas-Campos, D., Bettencourt, B. F., Bruges-Armas, J., Houlden, H., Heutink, P., Jardim, L. B., Sequeiros, J., Maciel, P., & Lima, M. (2021). Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing. Neurobiology of disease, 162105578. https://doi.org/10.1016/j.nbd.2021.105578
Raposo, Mafalda, et al. "Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing." Neurobiology of disease vol. 162 (2021): 105578. doi: https://doi.org/10.1016/j.nbd.2021.105578
Raposo M, Bettencourt C, Melo ARV, Ferreira AF, Alonso I, Silva P, Vasconcelos J, Kay T, Saraiva-Pereira ML, Costa MD, Vilasboas-Campos D, Bettencourt BF, Bruges-Armas J, Houlden H, Heutink P, Jardim LB, Sequeiros J, Maciel P, Lima M. Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing. Neurobiol Dis. 2021 Dec 03;162:105578. doi: 10.1016/j.nbd.2021.105578. Epub 2021 Dec 03. PMID: 34871736.
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Acute inhibition of dopamine β-hydroxylase attenuates behavioral responses to pups in adult virgin California mice (Peromyscus californicus).

Hormones and behavior

Acosta MC, Tillage RP, Weinshenker D, Saltzman W.
PMID: 34808463
Horm Behav. 2021 Nov 19;137:105086. doi: 10.1016/j.yhbeh.2021.105086. Epub 2021 Nov 19.

In biparental species, in which both parents care for their offspring, the neural and endocrine mediators of paternal behavior appear to overlap substantially with those underlying maternal behavior. Little is known, however, about the roles of classical neurotransmitters, such...

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Acosta MC, Tillage RP, Weinshenker D, et al. Acute inhibition of dopamine β-hydroxylase attenuates behavioral responses to pups in adult virgin California mice (Peromyscus californicus). Horm Behav. 2021;137:105086doi: 10.1016/j.yhbeh.2021.105086.
Acosta, M. C., Tillage, R. P., Weinshenker, D., & Saltzman, W. (2021). Acute inhibition of dopamine β-hydroxylase attenuates behavioral responses to pups in adult virgin California mice (Peromyscus californicus). Hormones and behavior, 137105086. https://doi.org/10.1016/j.yhbeh.2021.105086
Acosta, Melina C, et al. "Acute inhibition of dopamine β-hydroxylase attenuates behavioral responses to pups in adult virgin California mice (Peromyscus californicus)." Hormones and behavior vol. 137 (2021): 105086. doi: https://doi.org/10.1016/j.yhbeh.2021.105086
Acosta MC, Tillage RP, Weinshenker D, Saltzman W. Acute inhibition of dopamine β-hydroxylase attenuates behavioral responses to pups in adult virgin California mice (Peromyscus californicus). Horm Behav. 2021 Nov 19;137:105086. doi: 10.1016/j.yhbeh.2021.105086. Epub 2021 Nov 19. PMID: 34808463.
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Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing.

Neurobiology of disease

Raposo M, Bettencourt C, Melo ARV, Ferreira AF, Alonso I, Silva P, Vasconcelos J, Kay T, Saraiva-Pereira ML, Costa MD, Vilasboas-Campos D, Bettencourt BF, Bruges-Armas J, Houlden H, Heutink P, Jardim LB, Sequeiros J, Maciel P, Lima M.
PMID: 34871736
Neurobiol Dis. 2021 Dec 03;162:105578. doi: 10.1016/j.nbd.2021.105578. Epub 2021 Dec 03.

Machado-Joseph disease (MJD/SCA3) is a neurodegenerative polyglutamine disorder exhibiting a wide spectrum of phenotypes. The abnormal size of the (CAG)n at ATXN3 explains ~55% of the age at onset variance, suggesting the involvement of other factors, namely genetic modifiers,...

Cite
Raposo M, Bettencourt C, Melo ARV, et al. Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing. Neurobiol Dis. 2021;162:105578doi: 10.1016/j.nbd.2021.105578.
Raposo, M., Bettencourt, C., Melo, A. R. V., Ferreira, A. F., Alonso, I., Silva, P., Vasconcelos, J., Kay, T., Saraiva-Pereira, M. L., Costa, M. D., Vilasboas-Campos, D., Bettencourt, B. F., Bruges-Armas, J., Houlden, H., Heutink, P., Jardim, L. B., Sequeiros, J., Maciel, P., & Lima, M. (2021). Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing. Neurobiology of disease, 162105578. https://doi.org/10.1016/j.nbd.2021.105578
Raposo, Mafalda, et al. "Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing." Neurobiology of disease vol. 162 (2021): 105578. doi: https://doi.org/10.1016/j.nbd.2021.105578
Raposo M, Bettencourt C, Melo ARV, Ferreira AF, Alonso I, Silva P, Vasconcelos J, Kay T, Saraiva-Pereira ML, Costa MD, Vilasboas-Campos D, Bettencourt BF, Bruges-Armas J, Houlden H, Heutink P, Jardim LB, Sequeiros J, Maciel P, Lima M. Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing. Neurobiol Dis. 2021 Dec 03;162:105578. doi: 10.1016/j.nbd.2021.105578. Epub 2021 Dec 03. PMID: 34871736.
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[No title available]

Journal of neurology, neurosurgery, and psychiatry

Oliveira FPM, Walker Z, Walker RWH, Attems J, Castanheira JC, Silva Â, Oliveira C, Vaz S, Silva M, Costa DC.
PMID: 33542085
J Neurol Neurosurg Psychiatry. 2021 Feb 04; doi: 10.1136/jnnp-2020-324606. Epub 2021 Feb 04.

PURPOSE: The aim of this study was to re-evaluate the differentiation of patients with dementia with Lewy bodies (DLB) from Alzheimer's disease (AD) and Parkinson's disease (PD) using a quantitative analysis of METHODS: Thirty-six patients with in vivo RESULTS:...

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Oliveira FPM, Walker Z, Walker RWH, et al. . J Neurol Neurosurg Psychiatry. 2021;doi: 10.1136/jnnp-2020-324606.
Oliveira, F. P. M., Walker, Z., Walker, R. W. H., Attems, J., Castanheira, J. C., Silva, �. �., Oliveira, C., Vaz, S., Silva, M., & Costa, D. C. (2021). . Journal of neurology, neurosurgery, and psychiatry, . https://doi.org/10.1136/jnnp-2020-324606
Oliveira, Francisco P M, et al. "." Journal of neurology, neurosurgery, and psychiatry vol. (2021). doi: https://doi.org/10.1136/jnnp-2020-324606
Oliveira FPM, Walker Z, Walker RWH, Attems J, Castanheira JC, Silva Â, Oliveira C, Vaz S, Silva M, Costa DC. . J Neurol Neurosurg Psychiatry. 2021 Feb 04; doi: 10.1136/jnnp-2020-324606. Epub 2021 Feb 04. PMID: 33542085.
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Annato extract and β-carotene modulate the production of reactive oxygen species/nitric oxide in neutrophils from diabetic rats.

Journal of clinical biochemistry and nutrition

Rossoni-Júnior JV, Araújo GR, Pádua Bda C, Chaves MM, Pedrosa ML, Silva ME, Costa DC.
PMID: 22573917
J Clin Biochem Nutr. 2012 May;50(3):177-83. doi: 10.3164/jcbn.11-49. Epub 2011 Dec 07.

Annatto has been identified as carotenoids that have antioxidative effects. It is well known that one of the key elements in the development of diabetic complications is oxidative stress. The immune system is especially vulnerable to oxidative damage because...

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Rossoni-Júnior JV, Araújo GR, Pádua Bda C, et al. Annato extract and β-carotene modulate the production of reactive oxygen species/nitric oxide in neutrophils from diabetic rats. J Clin Biochem Nutr. 2011;50(3):177-83doi: 10.3164/jcbn.11-49.
Rossoni-Júnior, J. V., Araújo, G. R., Pádua, B. d. a. . C., Chaves, M. M., Pedrosa, M. L., Silva, M. E., & Costa, D. C. (2012). Annato extract and β-carotene modulate the production of reactive oxygen species/nitric oxide in neutrophils from diabetic rats. Journal of clinical biochemistry and nutrition, 50(3), 177-83. https://doi.org/10.3164/jcbn.11-49
Rossoni-Júnior, Joamyr Victor, et al. "Annato extract and β-carotene modulate the production of reactive oxygen species/nitric oxide in neutrophils from diabetic rats." Journal of clinical biochemistry and nutrition vol. 50,3 (2012): 177-83. doi: https://doi.org/10.3164/jcbn.11-49
Rossoni-Júnior JV, Araújo GR, Pádua Bda C, Chaves MM, Pedrosa ML, Silva ME, Costa DC. Annato extract and β-carotene modulate the production of reactive oxygen species/nitric oxide in neutrophils from diabetic rats. J Clin Biochem Nutr. 2012 May;50(3):177-83. doi: 10.3164/jcbn.11-49. Epub 2011 Dec 07. PMID: 22573917; PMCID: PMC3334368.
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Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing.

Neurobiology of disease

Raposo M, Bettencourt C, Melo ARV, Ferreira AF, Alonso I, Silva P, Vasconcelos J, Kay T, Saraiva-Pereira ML, Costa MD, Vilasboas-Campos D, Bettencourt BF, Bruges-Armas J, Houlden H, Heutink P, Jardim LB, Sequeiros J, Maciel P, Lima M.
PMID: 34871736
Neurobiol Dis. 2021 Dec 03;162:105578. doi: 10.1016/j.nbd.2021.105578. Epub 2021 Dec 03.

Machado-Joseph disease (MJD/SCA3) is a neurodegenerative polyglutamine disorder exhibiting a wide spectrum of phenotypes. The abnormal size of the (CAG)n at ATXN3 explains ~55% of the age at onset variance, suggesting the involvement of other factors, namely genetic modifiers,...

Cite
Raposo M, Bettencourt C, Melo ARV, et al. Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing. Neurobiol Dis. 2021;162:105578doi: 10.1016/j.nbd.2021.105578.
Raposo, M., Bettencourt, C., Melo, A. R. V., Ferreira, A. F., Alonso, I., Silva, P., Vasconcelos, J., Kay, T., Saraiva-Pereira, M. L., Costa, M. D., Vilasboas-Campos, D., Bettencourt, B. F., Bruges-Armas, J., Houlden, H., Heutink, P., Jardim, L. B., Sequeiros, J., Maciel, P., & Lima, M. (2021). Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing. Neurobiology of disease, 162105578. https://doi.org/10.1016/j.nbd.2021.105578
Raposo, Mafalda, et al. "Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing." Neurobiology of disease vol. 162 (2021): 105578. doi: https://doi.org/10.1016/j.nbd.2021.105578
Raposo M, Bettencourt C, Melo ARV, Ferreira AF, Alonso I, Silva P, Vasconcelos J, Kay T, Saraiva-Pereira ML, Costa MD, Vilasboas-Campos D, Bettencourt BF, Bruges-Armas J, Houlden H, Heutink P, Jardim LB, Sequeiros J, Maciel P, Lima M. Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing. Neurobiol Dis. 2021 Dec 03;162:105578. doi: 10.1016/j.nbd.2021.105578. Epub 2021 Dec 03. PMID: 34871736.
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Showing 229 to 234 of 234 entries