Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 13 to 24 of 24 entries
Sorted by: Best Match Show Resources per page
New-onset atrial fibrillation incidence and associated outcomes in the medical intensive care unit.

Pacing and clinical electrophysiology : PACE

Brunetti R, Zitelny E, Newman N, Bundy R, Singleton MJ, Dowell J, Dharod A, Bhave PD.
PMID: 34173671
Pacing Clin Electrophysiol. 2021 Aug;44(8):1380-1386. doi: 10.1111/pace.14301. Epub 2021 Jul 06.

BACKGROUND: In patients with critical medical illness, data regarding new-onset atrial fibrillation (NOAF) is relatively sparse. This study examines the incidence, associated risk factors, and associated outcomes of NOAF in patients in the medical intensive care unit (MICU).METHODS: This...

How To Hospital: barriers to developing a patient 'Hospital Survival Guide' to support information transfer during ward-rounds on the patient journey from admission to hospital to discharge.

BMJ open quality

Lewis S, Jones GM, Barach P, Tomos H, Davies M, Eckley B, Dowell HR, Subbe CP.
PMID: 34983802
BMJ Open Qual. 2022 Jan;11(1). doi: 10.1136/bmjoq-2021-001556.

Clinicians can enable patients to actively participate in their care but communication with patients is often poor and highly variable. The aim of this study was to explore patients' understanding of their current illness while in hospital and using...

What to do about medical students with unsatisfactory consultation skills?.

Medical teacher

Dowell J, Dent JA, Duffy R.
PMID: 16973458
Med Teach. 2006 Aug;28(5):443-6. doi: 10.1080/01421590600627516.

If it is accepted that new doctors must be 'Fit to Practice' in a standard clinical house job, they should be competent in basic communication skills. Although these skills may be assessed as part of a routine OSCE-style exam...

Receptor activity-modifying protein-directed G protein signaling specificity for the calcitonin gene-related peptide family of receptors.

The Journal of biological chemistry

Weston C, Winfield I, Harris M, Hodgson R, Shah A, Dowell SJ, Mobarec JC, Woodcock DA, Reynolds CA, Poyner DR, Watkins HA, Ladds G.
PMID: 27913664
J Biol Chem. 2016 Dec 02;291(49):25763. doi: 10.1074/jbc.A116.751362.

No abstract available.

Discovery of a Selective S1P1 Receptor Agonist Efficacious at Low Oral Dose and Devoid of Effects on Heart Rate.

ACS medicinal chemistry letters

Demont EH, Andrews BI, Bit RA, Campbell CA, Cooke JW, Deeks N, Desai S, Dowell SJ, Gaskin P, Gray JR, Haynes A, Holmes DS, Kumar U, Morse MA, Osborne GJ, Panchal T, Patel B, Perboni A, Taylor S, Watson R, Witherington J, Willis R.
PMID: 24900328
ACS Med Chem Lett. 2011 Mar 24;2(6):444-9. doi: 10.1021/ml2000214. eCollection 2011 Jun 09.

Gilenya (fingolimod, FTY720) was recently approved by the U.S. FDA for the treatment of patients with remitting relapsing multiple sclerosis (RRMS). It is a potent agonist of four of the five sphingosine 1-phosphate (S1P) G-protein-coupled receptors (S1P1 and S1P3-5)....

Towards a conception for an engineering discipline of human factors.

Ergonomics

Dowell J, Long J.
PMID: 28080937
Ergonomics. 1989 Nov;32(11):1513-1535. doi: 10.1080/00140138908966921.

This paper concerns one possible response of human factors to the need for better user interactions of computer-based systems. The paper is in two parts. Part I examines the potential for human factors to formulate engineering principles. A basic...

Correction to Discovery of Novel Adenosine Receptor Agonists That Exhibit Subtype Selectivity.

Journal of medicinal chemistry

Knight A, Hemmings JL, Winfield I, Leuenberger M, Frattini E, Frenguelli BG, Dowell SJ, Lochner M, Ladds G.
PMID: 32870678
J Med Chem. 2020 Sep 24;63(18):10531. doi: 10.1021/acs.jmedchem.0c01416. Epub 2020 Sep 01.

No abstract available.

Development of an orthotopic canine prostate cancer model expressing human GRPr.

The Prostate

Tweedle MF, Ding H, Drost WT, Dowell J, Spain J, Joseph M, Elshafae SM, Menendez MI, Gong L, Kothandaraman S, Dirksen WP, Wright CL, Bahnson R, Knopp MV, Rosol TJ.
PMID: 29992622
Prostate. 2018 Jul 11; doi: 10.1002/pros.23686. Epub 2018 Jul 11.

BACKGROUND: Ace-1 canine prostate cancer cells grow orthotopically in cyclosporine immunosuppressed laboratory beagles. We previously transfected (human Gastrin-Releasing Peptide Receptor, huGRPr) into Ace-1 cells and demonstrated receptor-targeted NIRF imaging with IR800-G-Abz4-t-BBN, an agonist to huGRPr. Herein, we used the...

THE PSYCHIATRIST AND THE EYE.

IMJ. Illinois medical journal

DRELL HJ.
PMID: 14246458
IMJ Ill Med J. 1964 Oct;126:428-30.

No abstract available.

Response to Adam et al. regarding selection methods.

Medical education

Patterson F, Knight A, Dowell J, Nicholson S, Cousans F, Cleland J.
PMID: 28244224
Med Educ. 2017 Jun;51(6):670. doi: 10.1111/medu.13251. Epub 2017 Feb 27.

No abstract available.

Chiari 1 Malformation Presenting as Central Sleep Apnea during Pregnancy: A Case Report, Treatment Considerations, and Review of the Literature.

Frontiers in neurology

St Louis EK, Jinnur P, McCarter SJ, Duwell EJ, Benarroch EE, Kantarci K, Pichelmann MA, Silber MH, Boeve BF, Olson EJ, Morgenthaler TI, Somers VK.
PMID: 25386156
Front Neurol. 2014 Oct 24;5:195. doi: 10.3389/fneur.2014.00195. eCollection 2014.

PURPOSE: Chiari malformation (CM) type-1 frequently causes obstructive or central sleep-disordered breathing (SDB) in both adults and children, although SDB is relatively rare as a presenting manifestation in the absence of other neurological symptoms. The definitive treatment of symptomatic...

BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity.

The Journal of experimental medicine

Bittner ZA, Liu X, Mateo Tortola M, Tapia-Abellán A, Shankar S, Andreeva L, Mangan M, Spalinger M, Kalbacher H, Düwell P, Lovotti M, Bosch K, Dickhöfer S, Marcu A, Stevanović S, Herster F, Cardona Gloria Y, Chang TH, Bork F, Greve CL, Löffler MW, Wolz OO, Schilling NA, Kümmerle-Deschner JB, Wagner S, Delor A, Grimbacher B, Hantschel O, Scharl M, Wu H, Latz E, Weber ANR.
PMID: 34554188
J Exp Med. 2021 Nov 01;218(11). doi: 10.1084/jem.20201656. Epub 2021 Sep 23.

Activity of the NLRP3 inflammasome, a critical mediator of inflammation, is controlled by accessory proteins, posttranslational modifications, cellular localization, and oligomerization. How these factors relate is unclear. We show that a well-established drug target, Bruton's tyrosine kinase (BTK), affects...

Showing 13 to 24 of 24 entries