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Showing 13 to 24 of 122 entries
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Sustained, complete response to pexidartinib in a patient with CSF1R-mutated Erdheim-Chester disease.

American journal of hematology

Abeykoon JP, Lasho TL, Dasari S, Rech KL, Ranatunga WK, Manske MK, Tischer A, Ravindran A, Young JR, Tobin WO, Flanagan EP, Nowakowski KE, Ruan GJ, Shah MV, Bennani NN, Vassallo R, Ryu JH, Koster MJ, Davidge-Pitts CJ, Patnaik MM, Wu X, Witzig TE, Goyal G, Go RS.
PMID: 34978715
Am J Hematol. 2022 Jan 03; doi: 10.1002/ajh.26441. Epub 2022 Jan 03.

Erdheim-Chester disease (ECD) is a histiocytic neoplasm that predominantly harbors mitogen-activated protein kinase (MAPK) pathway variants. MAPK inhibitors typically are effective treatments, but mutations outside the MAPK pathway, such as CSF1R variants, may cause refractory ECD. We describe a...

DiODe v2: Unambiguous and Fully-Automated Detection of Directional DBS Lead Orientation.

Brain sciences

Dembek TA, Hellerbach A, Jergas H, Eichner M, Wirths J, Dafsari HS, Barbe MT, Hunsche S, Visser-Vandewalle V, Treuer H.
PMID: 34827449
Brain Sci. 2021 Oct 31;11(11). doi: 10.3390/brainsci11111450.

Directional deep brain stimulation (DBS) leads are now widely used, but the orientation of directional leads needs to be taken into account when relating DBS to neuroanatomy. Methods that can reliably and unambiguously determine the orientation of directional DBS...

Targeted Detection of SARS-CoV-2 Nucleocapsid Sequence Variants by Mass Spectrometric Analysis of Tryptic Peptides.

Journal of proteome research

Maus A, Renuse S, Kemp J, Madugundu AK, Vanderboom PM, Blommel J, Jerde C, Dasari S, Kipp BR, Singh RJ, Grebe SK, Pandey A.
PMID: 34779632
J Proteome Res. 2022 Jan 07;21(1):142-150. doi: 10.1021/acs.jproteome.1c00613. Epub 2021 Nov 15.

COVID-19 vaccines are becoming more widely available, but accurate and rapid testing remains a crucial tool for slowing the spread of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus. Although the quantitative reverse transcription-polymerase chain reaction (qRT-PCR) remains the...

MASS-FIX for the detection of monoclonal proteins and light chain N-glycosylation in routine clinical practice: a cross-sectional study of 6315 patients.

Blood cancer journal

Mellors PW, Dasari S, Kohlhagen MC, Kourelis T, Go RS, Muchtar E, Gertz MA, Kumar SK, Buadi FK, Willrich MAV, Lust JA, Kapoor P, Lacy MQ, Dingli D, Hwa Y, Fonder A, Hobbs M, Hayman S, Warsame R, Leung NR, Lin Y, Gonsalves W, Siddiqui M, Kyle RA, Rajkumar SV, Murray DL, Dispenzieri A.
PMID: 33664227
Blood Cancer J. 2021 Mar 04;11(3):50. doi: 10.1038/s41408-021-00444-0.

Immunoenrichment-based matrix assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS), termed MASS-FIX, offers several advantages over immunofixation for the detection and isotyping of serum monoclonal protein, including superior sensitivity and specificity, the ability to differentiate therapeutic monoclonal antibodies, and...

Thalamic Deep Brain Stimulation in Essential Tremor Plus Is as Effective as in Essential Tremor.

Brain sciences

Steffen JK, Jergas H, Petry-Schmelzer JN, Dembek TA, Thies T, Jost ST, Dafsari HS, Kessler J, Wirths J, Fink GR, Visser-Vandewalle V, Barbe MT.
PMID: 33322350
Brain Sci. 2020 Dec 11;10(12). doi: 10.3390/brainsci10120970.

The new essential tremor (ET) classification defined ET-plus (ET-p) as an ET subgroup with additional neurological signs besides action tremor. While deep brain stimulation (DBS) is effective in ET, there are no studies specifically addressing DBS effects in ET-p....

Impaired Muscle Mitochondrial Function in Familial Partial Lipodystrophy.

The Journal of clinical endocrinology and metabolism

Simha V, Lanza IR, Dasari S, Klaus KA, Le Brasseur N, Vuckovic I, Laurenti MC, Cobelli C, Port JD, Nair KS.
PMID: 34614176
J Clin Endocrinol Metab. 2021 Oct 06; doi: 10.1210/clinem/dgab725. Epub 2021 Oct 06.

BACKGROUND: Familial Partial Lipodystrophy (FPL), Dunnigan variety is characterized by skeletal muscle hypertrophy and insulin resistance besides fat loss from the extremities. The cause for the muscle hypertrophy, and its functional consequences is not known.OBJECTIVE: To compare muscle strength...

Donor-Derived ALECT2 Amyloidosis and Recurrent Fibrillary Glomerulonephritis in a Transplant Allograft.

Kidney medicine

Nasr SH, Chavez O, Dasari S, Theis JD, Vrana JA, Fatima H, Fu L, Baliga RS, McPhail ED.
PMID: 34136788
Kidney Med. 2021 Feb 16;3(3):433-437. doi: 10.1016/j.xkme.2020.11.019. eCollection 2021.

The occurrence of renal amyloidosis and fibrillary glomerulonephritis in the same biopsy specimen is exceptional and poses a diagnostic challenge. We describe the case of a non-Hispanic White patient with end-stage kidney disease due to fibrillary glomerulonephritis who received...

Optical Microangiography and Progressive Retinal Nerve Fiber Layer Loss in Primary Open Angle Glaucoma.

American journal of ophthalmology

Rao HL, Dasari S, Puttaiah NK, Pradhan ZS, Moghimi S, Mansouri K, Webers CAB, Weinreb RN.
PMID: 34320375
Am J Ophthalmol. 2022 Jan;233:171-179. doi: 10.1016/j.ajo.2021.07.023. Epub 2021 Jul 25.

PURPOSE: To evaluate the association between optical microangiography (OMAG) measurements and progressive retinal nerve fiber layer (RNFL) loss in primary open angle glaucoma (POAG).DESIGN: Prospective case series.METHODS: Sixty-four eyes of 40 patients with POAG (108 quadrants) with mild to...

Predictors of short-term impulsive and compulsive behaviour after subthalamic stimulation in Parkinson disease.

Journal of neurology, neurosurgery, and psychiatry

Sauerbier A, Loehrer P, Jost ST, Heil S, Petry-Schmelzer JN, Herberg J, Bachon P, Aloui S, Gronostay A, Klingelhoefer L, Baldermann JC, Huys D, Nimsky C, Barbe MT, Fink GR, Martinez-Martin P, Ray Chaudhuri K, Visser-Vandewalle V, Timmermann L, Weintraub D, Dafsari HS.
PMID: 34510000
J Neurol Neurosurg Psychiatry. 2021 Dec;92(12):1313-1318. doi: 10.1136/jnnp-2021-326131. Epub 2021 Sep 11.

BACKGROUND: The effects of subthalamic stimulation (subthalamic nucleus-deep brain stimulation, STN-DBS) on impulsive and compulsive behaviours (ICB) in Parkinson's disease (PD) are understudied.OBJECTIVE: To investigate clinical predictors of STN-DBS effects on ICB.METHODS: In this prospective, open-label, multicentre study in...

Erratum. TFAM Enhances Fat Oxidation and Attenuates High-Fat Diet-Induced Insulin Resistance in Skeletal Muscle. Diabetes 2019;68:1552-1564.

Diabetes

Koh JH, Johnson ML, Dasari S, LeBrasseur NK, Vuckovic I, Henderson GC, Cooper SA, Manjunatha S, Ruegsegger GN, Shulman GI, Lanza IR, Nair KS.
PMID: 32532806
Diabetes. 2020 Aug;69(8):1854. doi: 10.2337/db20-er08a. Epub 2020 Jun 12.

No abstract available.

Referenced scans improve the repeatability of optical coherence tomography angiography measurements in normal and glaucoma eyes.

The British journal of ophthalmology

Rao HL, Dasari S, Riyazuddin M, Lavanya R, P NK, Pradhan ZS, Moghimi S, Mansouri K, Webers CAB, Weinreb RN.
PMID: 32962991
Br J Ophthalmol. 2021 Nov;105(11):1542-1547. doi: 10.1136/bjophthalmol-2020-316480. Epub 2020 Sep 22.

AIM: To compare the repeatability of peripapillary perfusion density and flux index measurements on referenced and non-referenced optical microangiography (OMAG) scans in normal, glaucoma suspect and glaucoma eyes.METHODS: In a cross-sectional study, 48 eyes (33 subjects) underwent three repeat,...

Somatostatin-derived amyloidosis: a novel type of amyloidosis associated with well-differentiated somatostatin-producing neuroendocrine tumours.

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis

Van Treeck BJ, Dasari S, Kurtin PJ, Theis JD, Nasr SH, Zhang L, Yasir S, Graham RP, McPhail ED, Said S.
PMID: 34541974
Amyloid. 2021 Sep 20;1-6. doi: 10.1080/13506129.2021.1979512. Epub 2021 Sep 20.

OBJECTIVE: To report the clinicopathologic and proteomic characteristics of a novel form of amyloidosis derived from the precursor protein somatostatin.MATERIALS AND METHODS: Cases were identified by searching the Mayo Clinic amyloid liquid chromatography and tandem mass spectrometry (LC-MS/MS) typing...

Showing 13 to 24 of 122 entries