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Showing 25 to 36 of 188 entries
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Antitumor activity of novel POLA1-HDAC11 dual inhibitors.

European journal of medicinal chemistry

Dallavalle S, Musso L, Cincinelli R, Darwiche N, Gervasoni S, Vistoli G, Guglielmi MB, La Porta I, Pizzulo M, Modica E, Prosperi F, Signorino G, Colelli F, Cardile F, Fucci A, D'Andrea EL, Riccio A, Pisano C.
PMID: 34772529
Eur J Med Chem. 2022 Jan 15;228:113971. doi: 10.1016/j.ejmech.2021.113971. Epub 2021 Nov 03.

Hybrid molecules targeting simultaneously DNA polymerase α (POLA1) and histone deacetylases (HDACs) were designed and synthesized to exploit a potential synergy of action. Among a library of screened molecules, MIR002 and GEM144 showed antiproliferative activity at nanomolar concentrations on...

Delayed Gastric Emptying After Multivisceral Resection for Retroperitoneal Sarcoma.

Annals of surgical oncology

Baia M, Conti L, Pasquali S, Sarre-Lazcano C, Abatini C, Cioffi SPB, Della Valle S, Greco G, Vigorito R, Casirati A, Proto P, Gavazzi C, Gronchi A, Fiore M.
PMID: 35031920
Ann Surg Oncol. 2022 Jan 15; doi: 10.1245/s10434-021-11154-z. Epub 2022 Jan 15.

INTRODUCTION: Delayed gastric emptying (DGE) is a common complication in surgery, but incidence and relevance following multivisceral resection are unknown.METHODS: Data from 100 consecutive patients treated for primary retroperitoneal sarcoma (RPS) were analyzed from our institutional prospectively maintained database...

Zebrafish .

Zebrafish

Meneghetti G, Skobo T, Chrisam M, Fontana CM, Facchinello N, Nazio F, Cecconi F, Bonaldo P, Dalla Valle L.
PMID: 32320344
Zebrafish. 2020 Apr 22; doi: 10.1089/zeb.2020.1860. Epub 2020 Apr 22.

In zebrafish, two paralogous genes, activating molecule in beclin-1 (BECN1)-regulated autophagy

Quantitative Ultrafast Electron-Temperature Dynamics in Photo-Excited Au Nanoparticles.

Small (Weinheim an der Bergstrasse, Germany)

Sygletou M, Benedetti S, Ferrera M, Pierantozzi GM, Cucini R, Della Valle G, Carrara P, De Vita A, di Bona A, Torelli P, Catone D, Panaccione G, Canepa M, Bisio F.
PMID: 34061425
Small. 2021 Jul;17(26):e2100050. doi: 10.1002/smll.202100050. Epub 2021 Jun 01.

The femtosecond evolution of the electronic temperature of laser-excited gold nanoparticles is measured, by means of ultrafast time-resolved photoemission spectroscopy induced by extreme-ultraviolet radiation pulses. The temperature of the electron gas is deduced by recording and fitting high-resolution photo...

Recent advances in the synthesis of naturally occurring tetronic acids.

Bioorganic chemistry

Princiotto S, Jayasinghe L, Dallavalle S.
PMID: 34929518
Bioorg Chem. 2021 Dec 13;119:105552. doi: 10.1016/j.bioorg.2021.105552. Epub 2021 Dec 13.

During the last decades the interest towards natural products containing the tetronic acid moiety augmented significantly, due to their challenging structures and to the wide range of biological activities they display. This increasing enthusiasm has led to noteworthy advances...

Performance of Comprehensive Complication Index and Clavien-Dindo Complication Scoring System in Liver Surgery for Hepatocellular Carcinoma.

Cancers

Giani A, Cipriani F, Famularo S, Donadon M, Bernasconi DP, Ardito F, Fazio F, Nicolini D, Perri P, Giuffrida M, Pontarolo N, Zanello M, Lai Q, Conci S, Molfino S, Germani P, Pinotti E, Romano M, La Barba G, Ferrari C, Patauner S, Manzoni A, Sciannamea I, Fumagalli L, Troci A, Ferraro V, Floridi A, Memeo R, Crespi M, Chiarelli M, Antonucci A, Zimmitti G, Frena A, Percivale A, Ercolani G, Zanus G, Zago M, Tarchi P, Baiocchi GL, Ruzzenente A, Rossi M, Jovine E, Maestri M, Dalla Valle R, Grazi G, Vivarelli M, Ferrero A, Giuliante F, Torzilli G, Aldrighetti L, Gianotti L, Romano F, Ciulli C, Braga M, Ratti F, Costa G, Razionale F, Russolillo N, Marinelli L, De Peppo V, Cremaschi E, Calabrese F, Larghi Laureiro Z, Lazzari G, Cosola D, Montuori M, Salvador L, Cucchetti A, Franceschi A, Ciola M, Sega V, Calcagno P, Pennacchi L, Tedeschi M.
PMID: 33371419
Cancers (Basel). 2020 Dec 21;12(12). doi: 10.3390/cancers12123868.

BACKGROUND: We aimed to assess the ability of comprehensive complication index (CCI) and Clavien-Dindo complication (CDC) scale to predict excessive length of hospital stay (e-LOS) in patients undergoing liver resection for hepatocellular carcinoma.METHODS: Patients were identified from an Italian...

Optical tuning of dielectric nanoantennas for thermo-optically reconfigurable nonlinear metasurfaces.

Optics letters

Celebrano M, Rocco D, Gandolfi M, Zilli A, Rusconi F, Tognazzi A, Mazzanti A, Ghirardini L, Pogna EAA, Carletti L, Baratto C, Marino G, Gigli C, Biagioni P, Duò L, Cerullo G, Leo G, Della Valle G, Finazzi M, De Angelis C.
PMID: 33988608
Opt Lett. 2021 May 15;46(10):2453-2456. doi: 10.1364/OL.420790.

We demonstrate optically tunable control of second-harmonic generation in all-dielectric nanoantennas: by using a control beam that is absorbed by the nanoresonator, we thermo-optically change the refractive index of the radiating element to modulate the amplitude of the second-harmonic...

Curative versus palliative treatments for recurrent hepatocellular carcinoma: a multicentric weighted comparison.

HPB : the official journal of the International Hepato Pancreato Biliary Association

Famularo S, Donadon M, Cipriani F, Bernasconi DP, LaBarba G, Dominioni T, Iaria M, Molfino S, Conci S, Ferrari C, Garatti M, Delvecchio A, Troci A, Patauner S, Frassani S, Cosimelli M, Zanus G, Giuliante F, Jovine E, Valsecchi MG, Grazi G, Antonucci A, Frena A, Crespi M, Memeo R, Zimmitti G, Griseri G, Ruzzenente A, Baiocchi G, DallaValle R, Maestri M, Ercolani G, Aldrighetti L, Torzilli G, Romano F.
PMID: 33144053
HPB (Oxford). 2021 Jun;23(6):889-898. doi: 10.1016/j.hpb.2020.10.007. Epub 2020 Nov 02.

BACKGROUND: Management of recurrence after surgery for hepatocellular carcinoma (rHCC) is still a debate. The aim was to compare the Survival after Recurrence (SAR) of curative (surgery or thermoablation) versus palliative (TACE or Sorafenib) treatments for patients with rHCC.METHODS:...

Technical feasibility and short-term outcomes of laparoscopic isolated caudate lobe resection: an IgoMILS (Italian Group of Minimally Invasive Liver Surgery) registry-based study.

Surgical endoscopy

Ruzzenente A, Ciangherotti A, Aldrighetti L, Ettorre GM, De Carlis L, Ferrero A, Dalla Valle R, Tisone G, Guglielmi A.
PMID: 33788031
Surg Endosc. 2022 Feb;36(2):1490-1499. doi: 10.1007/s00464-021-08434-w. Epub 2021 Mar 31.

BACKGROUND: Although isolated caudate lobe (CL) liver resection is not a contraindication for minimally invasive liver surgery (MILS), feasibility and safety of the procedure are still poorly investigated. To address this gap, we evaluate data on the Italian prospective...

High-performance UV detector made of ultra-long ZnO bridging nanowires.

Nanotechnology

Li Y, Della Valle F, Simonnet M, Yamada I, Delaunay JJ.
PMID: 19417317
Nanotechnology. 2009 Jan 28;20(4):045501. doi: 10.1088/0957-4484/20/4/045501. Epub 2008 Dec 18.

A nanowatt UV photoconductive detector made up of ultra-long (approximately 100 microm) ZnO bridging nanowires has been fabricated by a single-step chemical vapor deposition (CVD) process. The electrodes, forming comb-shaped thick ZnO layers, and the sensing elements, consisting of...

Knockout of the .

International journal of molecular sciences

Theodoridi A, Dinarello A, Badenetti L, Pavlidis M, Dalla Valle L, Tsalafouta A.
PMID: 34830405
Int J Mol Sci. 2021 Nov 20;22(22). doi: 10.3390/ijms222212525.

The Hsd11b2 enzyme converts cortisol into its inactive form, cortisone and regulates cortisol levels, in particular in response to stress. Taking advantage of CRISPR/Cas9 technology, we generated a

Worksite Energy Cost Assessment in Non-surgical versus Surgical Medical Residency Programs.

The international journal of occupational and environmental medicine

Della Valle E, Sirico F, Cacciatore F, Palermi S, Marcantonio R, Spera R.
PMID: 31586386
Int J Occup Environ Med. 2019 Oct;10(4):216-217. doi: 10.15171/ijoem.2019.1617.

No abstract available.

Showing 25 to 36 of 188 entries