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Showing 1045 to 1050 of 1050 entries
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Author response to: Personal protective equipment impairs pulmonary gas exchange causing systemic hypercapnia-hypoxaemia and cerebral hyperperfusion-induced cephalalgia.

The British journal of surgery

James OP, Stacey B, Hopkins L, Robinson DBT, Luton O, Williams IM, Egan RJ, Bailey DM, Lewis WG.
PMID: 34738110
Br J Surg. 2021 Dec 01;108(12):e412. doi: 10.1093/bjs/znab369.

No abstract available.

Cardiac Transthyretin Amyloidosis: Hidden in Plain Sight.

Case reports in medicine

Logothetis CN, Fernandez J, Laber DA.
PMID: 34917152
Case Rep Med. 2021 Dec 07;2021:2551964. doi: 10.1155/2021/2551964. eCollection 2021.

Amyloidosis is an underappreciated medical condition with symptoms camouflaging as common medical comorbidities leading to its underdiagnosis due to its systemic involvement. Despite common misconceptions, amyloidosis and its systemic comorbidities are more prevalent and treatable than previously acknowledged by...

Jumping at a chance to control cerebral blood flow in astronauts.

Experimental physiology

Bailey DM, Ainslie PN, Petersen L, Zu Eulenburg P.
PMID: 33998091
Exp Physiol. 2021 Jul;106(7):1407-1409. doi: 10.1113/EP089648. Epub 2021 May 27.

No abstract available.

Multiparametric magnetic resonance imaging to characterize cabotegravir long-acting formulation depot kinetics in healthy adult volunteers.

British journal of clinical pharmacology

Jucker BM, Fuchs EJ, Lee S, Damian V, Galette P, Janiczek R, Macura KJ, Jacobs MA, Weld ED, Solaiyappan M, D'Amico R, Shaik JS, Bakshi K, Han K, Ford S, Margolis D, Spreen W, Gupta MK, Hendrix CW, Patel P.
PMID: 34240449
Br J Clin Pharmacol. 2021 Jul 08; doi: 10.1111/bcp.14977. Epub 2021 Jul 08.

AIM: Cabotegravir long-acting (LA) intramuscular (IM) injection is being investigated for HIV preexposure prophylaxis due to its potent antiretroviral activity and infrequent dosing requirement. A subset of healthy adult volunteers participating in a Phase I study assessing cabotegravir tissue...

Roles of steroid receptors in the lung and COVID-19.

Essays in biochemistry

Leach DA, Brooke GN, Bevan CL.
PMID: 34328182
Essays Biochem. 2021 Dec 17;65(6):1025-1038. doi: 10.1042/EBC20210005.

COVID-19 symptoms and mortality are largely due to its devastating effects in the lungs. The disease is caused by the SARS (Severe Acute Respiratory Syndrome)-CoV-2 coronavirus, which requires host cell proteins such as ACE2 (angiotensin-converting enzyme 2) and TMPRSS2...

A novel fluorescent c-met targeted imaging agent for intra-operative colonic tumour mapping: Translation from the laboratory into a clinical trial.

Surgical oncology

Armstrong GR, Khot MI, Portal C, West NP, Perry SL, Maisey TI, Tiernan JP, Hughes TA, Tolan DJ, Jayne DG.
PMID: 34839199
Surg Oncol. 2021 Nov 20;40:101679. doi: 10.1016/j.suronc.2021.101679. Epub 2021 Nov 20.

BACKGROUND: The c-Met protein is overexpressed in many gastrointestinal cancers. We explored EMI-137, a novel c-Met targeting fluorescent probe, for application in fluorescence-guided colon surgery, in HT-29 colorectal cancer (CRC) cell line and an in vivo murine model.METHODS: HT-29...

Showing 1045 to 1050 of 1050 entries