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Showing 661 to 670 of 670 entries
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Designing nanoformulation for the nose-to-brain delivery in Parkinson's disease: Advancements and barrier.

Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology

Kiran P, Debnath SK, Neekhra S, Pawar V, Khan A, Dias F, Pallod S, Srivastava R.
PMID: 34825510
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2021 Nov 25;e1768. doi: 10.1002/wnan.1768. Epub 2021 Nov 25.

Parkinson's disease (PD), a neurodegenerative disorder characterized by the degeneration of dopaminergic neurons, which results in the loss of motor activity. In the management of PD, the primary aim is to increase the dopamine content in the brain either...

Emerging roles for the autophagy machinery in extracellular vesicle biogenesis and secretion.

FASEB bioAdvances

Leidal AM, Debnath J.
PMID: 33977236
FASEB Bioadv. 2021 Mar 02;3(5):377-386. doi: 10.1096/fba.2020-00138. eCollection 2021 May.

Autophagy classically functions to maintain cell health during stressful conditions by targeting cytosolic components for degradation and recycling via lysosomal pathways. However, accumulating evidence also supports roles for autophagy-related genes (ATGs) in non-degradative processes including cellular secretion. Here, we...

Complete mitochondrial genome annotation of the giant intestinal fluke, .

Mitochondrial DNA. Part B, Resources

Biswal DK, Konhar R, Debnath M, Tandon V.
PMID: 34395880
Mitochondrial DNA B Resour. 2016 Sep 01;1(1):693-695. doi: 10.1080/23802359.2016.1222249. eCollection 2016.

The complete mitogenome sequences of the intestinal fluke

Surface Chemistry- and Intracellular Trafficking-Dependent Autophagy Induction by Iron Oxide Nanoparticles.

ACS applied bio materials

Panja P, Debnath K, Jana NR, Jana NR.
PMID: 35021826
ACS Appl Bio Mater. 2020 Sep 21;3(9):5974-5983. doi: 10.1021/acsabm.0c00640. Epub 2020 Aug 17.

Autophagy is a cellular self-clearance process for maintaining regular cytoplasmic function, and modulation of autophagy can influence cytotoxicity, apoptosis, and clearance of toxic amyloid fibril. In a recent work, functional nanoparticles are used to modulate autophagy. However, the role...

Bioprospecting of indigenous biosurfactant-producing oleophilic bacteria for green remediation: an eco-sustainable approach for the management of petroleum contaminated soil.

3 Biotech

Bharali P, Bashir Y, Ray A, Dutta N, Mudoi P, Alemtoshi, Sorhie V, Vishwakarma V, Debnath P, Konwar BK.
PMID: 34966636
3 Biotech. 2022 Jan;12(1):13. doi: 10.1007/s13205-021-03068-0. Epub 2021 Dec 09.

In the present study, the efficiency of four different strains of

Quercetin Encapsulated Polymer Nanoparticle for Inhibiting Intracellular Polyglutamine Aggregation.

ACS applied bio materials

Debnath K, Jana NR, Jana NR.
PMID: 35021530
ACS Appl Bio Mater. 2019 Dec 16;2(12):5298-5305. doi: 10.1021/acsabm.9b00518. Epub 2019 Sep 03.

Quercetin is a dietary flavonoid that shows effective neuroprotective action in cellular and animal models of Alzheimer's disease and Huntington's disease. However, its therapeutic application is limited due to low water solubility and cytotoxicity at the working concentration in...

HIV-1 gp120 Antagonists Also Inhibit HIV-1 Reverse Transcriptase by Bridging the NNRTI and NRTI Sites.

Journal of medicinal chemistry

Losada N, Ruiz FX, Curreli F, Gruber K, Pilch A, Das K, Debnath AK, Arnold E.
PMID: 34735153
J Med Chem. 2021 Nov 25;64(22):16530-16540. doi: 10.1021/acs.jmedchem.1c01104. Epub 2021 Nov 04.

HIV-1 infection is typically treated using ≥2 drugs, including at least one HIV-1 reverse transcriptase (RT) inhibitor. Drugs targeting RT comprise nucleos(t)ide RT inhibitors (NRTIs) and non-nucleoside RT inhibitors (NNRTIs). NRTI-triphosphates bind at the polymerase active site and, following...

Investigating the Efficacy of Adhesive Tape for Drilling Carbon Fibre Reinforced Polymers.

Materials (Basel, Switzerland)

Prakash C, Pramanik A, Basak AK, Dong Y, Debnath S, Shankar S, Singh S, Wu LY, Zheng HY.
PMID: 33808311
Materials (Basel). 2021 Mar 30;14(7). doi: 10.3390/ma14071699.

In the present research work, an effort has been made to explore the potential of using the adhesive tapes while drilling CFRPs. The input parameters, such as drill bit diameter, point angle, Scotch tape layers, spindle speed, and feed...

Accuracy of cholera rapid diagnostic tests: a systematic review and meta-analysis.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Muzembo BA, Kitahara K, Debnath A, Okamoto K, Miyoshi SI.
PMID: 34506946
Clin Microbiol Infect. 2021 Sep 15; doi: 10.1016/j.cmi.2021.08.027. Epub 2021 Sep 15.

BACKGROUND: Cholera is an acute diarrheal disease caused by Vibrio cholerae O1 or O139. Cholera rapid diagnostic tests (RDTs) are widely used to screen for cholera cases. However, their accuracy has not been systematically reviewed.OBJECTIVES: To evaluate the diagnostic...

Taking a mixed-methods approach to collision investigation: AcciMap, STAMP-CAST and PCM.

Applied ergonomics

Hamim OF, Hasanat-E-Rabbi S, Debnath M, Hoque MS, McIlroy RC, Plant KL, Stanton NA.
PMID: 34808534
Appl Ergon. 2021 Nov 19;100:103650. doi: 10.1016/j.apergo.2021.103650. Epub 2021 Nov 19.

Recently, ergonomics and safety researchers have turned their attention towards applying combinations of sociotechnical methods rather than using single methods in isolation. In the current research, a mixed-method approach combining two systems-based methods, Accimaps and the Systems Theoretic Accident...

Showing 661 to 670 of 670 entries