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Showing 25 to 36 of 43 entries
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HER2 Amplification Has no Prognostic Value in Sporadic and Hereditary Ovarian Tumours.

Hereditary cancer in clinical practice

Brozek I, Kardaś I, Ochman K, Debniak J, Stukan M, Ratajska M, Morzuch L, Emerich J, Limon J.
PMID: 20223002
Hered Cancer Clin Pract. 2006 Nov 15;4(1):39-42. doi: 10.1186/1897-4287-4-1-39.

Whereas HER2 amplification is a well-known phenomenon in breast tumours, its frequency and clinical importance in ovarian cancer have not been established. The aim of the study was to compare the frequency of HER2 amplification in hereditary (BRCA-positive) and...

Postoperative evaluation of hydronephrosis due to the way of pyeloplasy (dismembered / non-dismembered).

Central European journal of urology

Matuszewski M, Drewniak T, Juszczak K.
PMID: 24982796
Cent European J Urol. 2014;67(1):106-7. doi: 10.5173/ceju.2014.01.art25.

No abstract available.

Prognostic factors of overall survival in renal cancer patients - single oncological center study.

Central European journal of urology

Drewniak T, Sandheim M, Jakubowski J, Juszczak K, Stelmach AW.
PMID: 24707365
Cent European J Urol. 2013;66(3):283-91. doi: 10.5173/ceju.2013.03.art9. Epub 2013 Nov 18.

INTRODUCTION: The clinical course of renal cancer remains difficult to predict. Attempts to appoint new independent prognostic factors (IPFs) and comparisons of already identified ones among populations are inevitable to develop more effective prognostic instruments. The aim of this...

Dupuytren's disease and the risk of malignant neoplasms.

Hereditary cancer in clinical practice

Zyluk A, Paszkowska-Szczur K, Gupta S, Scott RJ, Lubiński J, Dębniak T.
PMID: 24598251
Hered Cancer Clin Pract. 2014 Mar 06;12(1):6. doi: 10.1186/1897-4287-12-6.

The object of this study was the investigation of the risk of occurrence of malignant neoplasms in 508 patients with Dupuytren's disease (DD) and in 2157 of their 1st degree relatives. In the first stage of the study, we...

Tailoring Properties of Resol Resin-Derived Spherical Carbons for Adsorption of Phenol from Aqueous Solution.

Molecules (Basel, Switzerland)

Sidor K, Berniak T, Łątka P, Rokicińska A, Michalik M, Kuśtrowski P.
PMID: 33808858
Molecules. 2021 Mar 19;26(6). doi: 10.3390/molecules26061736.

The polycondensation of resorcinol and formaldehyde in a water-ethanol mixture using the adapted Stöber method was used to obtain resol resins. An optimization of synthesis conditions and the use of an appropriate stabilizer (e.g., poly(vinyl alcohol)) resulted in spherical...

Variant identification in BARD1, PRDM9, RCC1, and RECQL in patients with ovarian cancer by targeted next-generation sequencing of DNA pools.

Cancer prevention research (Philadelphia, Pa.)

Suszynska M, Ratajska M, Galka-Marciniak P, Ryszkowska A, Wydra D, Debniak J, Jasiak A, Wasag B, Cybulski C, Kozlowski P.
PMID: 34906988
Cancer Prev Res (Phila). 2021 Dec 14; doi: 10.1158/1940-6207.CAPR-21-0295. Epub 2021 Dec 14.

Several ovarian cancer susceptibility genes have been discovered, but more are likely to exist. In this study, we aimed to analyze knowledge-based selected genes, i.e., BARD1, PRDM9, RCC1, and RECQL, in which pathogenic germline variants have been reported in...

Integrating Sex/Gender into Environmental Health Research: Development of a Conceptual Framework.

International journal of environmental research and public health

Bolte G, Jacke K, Groth K, Kraus U, Dandolo L, Fiedel L, Debiak M, Kolossa-Gehring M, Schneider A, Palm K.
PMID: 34831873
Int J Environ Res Public Health. 2021 Nov 18;18(22). doi: 10.3390/ijerph182212118.

There is a growing awareness about the need to comprehensively integrate sex and gender into health research in order to enhance the validity and significance of research results. An in-depth consideration of differential exposures and vulnerability is lacking, especially...

Do BARD1 Mutations Confer an Elevated Risk of Prostate Cancer?.

Cancers

Stempa K, Wokołorczyk D, Kluźniak W, Rogoża-Janiszewska E, Malińska K, Rudnicka H, Huzarski T, Gronwald J, Gliniewicz K, Dębniak T, Jakubowska A, Lener M, Tomiczek-Szwiec J, Domagała P, Suszynska M, Kozlowski P, Kluz T, Naczk M, Lubiński J, Narod SA, Akbari MR, Cybulski C, On Behalf Of The Polish Hereditary Prostate Cancer Consortium.
PMID: 34771627
Cancers (Basel). 2021 Oct 30;13(21). doi: 10.3390/cancers13215464.

The current cancer testing gene panels tend to be comprehensive rather than site-specific.

Familial malignant melanoma - overview.

Hereditary cancer in clinical practice

Debniak T.
PMID: 20233466
Hered Cancer Clin Pract. 2004 Jul 15;2(3):123-9. doi: 10.1186/1897-4287-2-3-123.

Approximately 3-15% of all malignant melanomas (MM) are familial cases. MM is a highly heterogeneous tumour type from a genetic perspective. Pedigrees with disease confined to a single generation of siblings or MM occurring among second- or third-degree relatives...

Coverage of the genetic background of breast cancer in the polish population.

Hereditary cancer in clinical practice

Serrano-Fernández P, Górski B, Debniak T, Cybulski C, Byrski T, Huzarski T, Gronwald J, Jakubowska A, Oszurek O, Lubiński J.
PMID: 20223000
Hered Cancer Clin Pract. 2006 Nov 15;4(1):25-7. doi: 10.1186/1897-4287-4-1-25.

No abstract available.

Inherited Variants in .

Cancers

Kluźniak W, Wokołorczyk D, Rusak B, Huzarski T, Kashyap A, Stempa K, Rudnicka H, Jakubowska A, Szwiec M, Morawska S, Gliniewicz K, Mordak K, Stawicka M, Jarkiewicz-Tretyn J, Cechowska M, Domagała P, Dębniak T, Lener M, Gronwald J, Lubiński J, Narod SA, Akbari MR, Cybulski C.
PMID: 31614901
Cancers (Basel). 2019 Oct 13;11(10). doi: 10.3390/cancers11101548.

Bloom Syndrome is a rare recessive disease which includes a susceptibility to various cancers. It is caused by homozygous mutations of the

Prevalence of Recurrent Mutations Predisposing to Breast Cancer in Early-Onset Breast Cancer Patients from Poland.

Cancers

Rogoża-Janiszewska E, Malińska K, Cybulski C, Jakubowska A, Gronwald J, Huzarski T, Lener M, Górski B, Kluźniak W, Rudnicka H, Akbari MR, Kashyap A, Narod SA, Lubiński J, Dębniak T, On Behalf Of The Polish Hereditary Breast Cancer Consortium.
PMID: 32824581
Cancers (Basel). 2020 Aug 17;12(8). doi: 10.3390/cancers12082321.

There are twenty recurrent mutations in six breast-cancer-predisposing genes in Poland (BRCA1, BRCA2, CHEK2, PALB2, NBN, and RECQL). The frequencies of the twenty alleles have not been measured in a large series of early-onset breast cancer patients from Poland...

Showing 25 to 36 of 43 entries