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Showing 145 to 146 of 146 entries
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Fluoroquinolones: With great power comes great risk.

Nursing

Kidd T, Mitchell S, Dehays J, Wibberley E.
PMID: 34879046
Nursing. 2021 Dec 07; doi: 10.1097/01.NURSE.0000800076.32210.46. Epub 2021 Dec 07.

ABSTRACT: Fluoroquinolones (FQs) are highly effective, well-tolerated, broad-spectrum antibiotics, making them desirable treatment options for infections. However, their adverse reactions as well as recent trends in antibiotic susceptibility must be considered. This article discusses the spectrum of activity and...

L-DOPA regulates α-synuclein accumulation in experimental parkinsonism.

Neuropathology and applied neurobiology

Deffains M, Canron MH, Teil M, Li Q, Dehay B, Bezard E, Fernagut PO.
PMID: 33275784
Neuropathol Appl Neurobiol. 2021 Jun;47(4):532-543. doi: 10.1111/nan.12678. Epub 2020 Dec 16.

AIMS: Widespread accumulation of misfolded α-synuclein aggregates is a key feature of Parkinson's disease (PD). Although the pattern and extent of α-synuclein accumulation through PD brains is known, the impact of chronic dopamine-replacement therapy (the gold-standard pharmacological treatment of...

Showing 145 to 146 of 146 entries