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Showing 289 to 300 of 300 entries
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Imaging Spectrum of Female Genital Tuberculosis: A Comprehensive Review.

Current problems in diagnostic radiology

Aggarwal A, Das CJ, Manchanda S.
PMID: 34304946
Curr Probl Diagn Radiol. 2021 Jul 06; doi: 10.1067/j.cpradiol.2021.06.014. Epub 2021 Jul 06.

Female genital tuberculosis is a relatively uncommon form of extrapulmonary tuberculosis that is under-reported and under-recognized. The early course of the disease has fewer manifestations, resulting in late presentation with grave complications like infertility and ectopic pregnancy. Also, difficulty...

Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth.

Cancer research

Cook DR, Kang M, Martin TD, Galanko JA, Loeza GH, Trembath DG, Justilien V, Pickering KA, Vincent DF, Jarosch A, Jurmeister P, Waters AM, Hibshman PS, Campbell AD, Ford CA, Keku TO, Yeh JJ, Lee MS, Cox AD, Fields AP, Sandler RS, Sansom OJ, Sers C, Schaefer A, Der CJ.
PMID: 34737214
Cancer Res. 2021 Nov 04; doi: 10.1158/0008-5472.CAN-20-4218. Epub 2021 Nov 04.

ECT2 is an activator of RHO GTPases that is essential for cytokinesis. Additionally, ECT2 was identified as an oncoprotein when expressed ectopically in NIH/3T3 fibroblasts. However, oncogenic activation of ECT2 resulted from N-terminal truncation, and such truncated ECT2 proteins...

Enhanced defense against ferroptosis ameliorates cognitive impairment and reduces neurodegeneration in 5xFAD mice.

Free radical biology & medicine

Chen L, Dar NJ, Na R, McLane KD, Yoo K, Han X, Ran Q.
PMID: 34998934
Free Radic Biol Med. 2022 Jan 06;180:1-12. doi: 10.1016/j.freeradbiomed.2022.01.002. Epub 2022 Jan 06.

Oxidative damage including lipid peroxidation is widely reported in Alzheimer's disease (AD) with the peroxidation of phospholipids in membranes being the driver of ferroptosis, an iron-dependent oxidative form of cell death. However, the importance of ferroptosis in AD remains...

Aberrant Expression and Subcellular Localization of ECT2 Drives Colorectal Cancer Progression and Growth.

Cancer research

Cook DR, Kang M, Martin TD, Galanko JA, Loeza GH, Trembath DG, Justilien V, Pickering KA, Vincent DF, Jarosch A, Jurmeister P, Waters AM, Hibshman PS, Campbell AD, Ford CA, Keku TO, Yeh JJ, Lee MS, Cox AD, Fields AP, Sandler RS, Sansom OJ, Sers C, Schaefer A, Der CJ.
PMID: 34737214
Cancer Res. 2022 Jan 01;82(1):90-104. doi: 10.1158/0008-5472.CAN-20-4218. Epub 2021 Nov 04.

ECT2 is an activator of RHO GTPases that is essential for cytokinesis. In addition, ECT2 was identified as an oncoprotein when expressed ectopically in NIH/3T3 fibroblasts. However, oncogenic activation of ECT2 resulted from N-terminal truncation, and such truncated ECT2...

U.S. Vietnamese parents' HPV vaccine decision-making for their adolescents: an exploration of practice-, provider-, and patient-level influences.

Journal of behavioral medicine

Vu M, Bednarczyk RA, Escoffery C, Ta D, Huynh VN, Berg CJ.
PMID: 34792723
J Behav Med. 2021 Nov 18; doi: 10.1007/s10865-021-00265-3. Epub 2021 Nov 18.

U.S. Vietnamese have high cervical cancer incidence and low human papillomavirus (HPV) vaccine initiation. Using the P3 model, we explored practice-, provider-, and patient-level determinants of U.S. Vietnamese parents' HPV vaccine decision-making for their adolescents. We conducted a cross-sectional,...

The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer.

The Journal of biological chemistry

Diehl JN, Klomp JE, Snare KR, Hibshman PS, Blake DR, Kaiser ZD, Gilbert TSK, Baldelli E, Pierobon M, Papke B, Yang R, Hodge RG, Rashid NU, Petricoin EF, Herring LE, Graves LM, Cox AD, Der CJ.
PMID: 34688654
J Biol Chem. 2021 Nov;297(5):101335. doi: 10.1016/j.jbc.2021.101335. Epub 2021 Oct 22.

Oncogenic KRAS drives cancer growth by activating diverse signaling networks, not all of which have been fully delineated. We set out to establish a system-wide profile of the KRAS-regulated kinase signaling network (kinome) in KRAS-mutant pancreatic ductal adenocarcinoma (PDAC)....

Correction: Structural basis for plant plasma membrane protein dynamics and organization into functional nanodomains.

eLife

Gronnier J, Crowet JM, Habenstein B, Nasir MN, Bayle V, Hosy E, Platre MP, Gouguet PB, Raffaele S, Martinez D, Grelard A, Loquet A, Simon-Plas F, Gerbeau-Pissot P, Der C, Bayer EM, Jaillais Y, Deleu M, Germain V, Lins L, Mongrand S.
PMID: 33502314
Elife. 2021 Jan 27;10. doi: 10.7554/eLife.66677.

No abstract available.

Surfactant free synthesis of cationic nano-vesicles: A safe triple drug loaded vehicle for the topical treatment of cutaneous leishmaniasis.

Nanomedicine : nanotechnology, biology, and medicine

Khalid S, Salman S, Iqbal K, Rehman FU, Ullah I, Satoskar AR, Khan GM, Dar MJ.
PMID: 34748957
Nanomedicine. 2021 Nov 05;40:102490. doi: 10.1016/j.nano.2021.102490. Epub 2021 Nov 05.

The basic aim of the study was to develop and evaluate the triple drug loaded cationic nano-vesicles (cNVs), where miltefosine was used as a replacement of surfactant (apart from its anti-leishmanial role), in addition to meglumine antimoniate (MAM) and...

Enhanced defense against ferroptosis ameliorates cognitive impairment and reduces neurodegeneration in 5xFAD mice.

Free radical biology & medicine

Chen L, Dar NJ, Na R, McLane KD, Yoo K, Han X, Ran Q.
PMID: 34998934
Free Radic Biol Med. 2022 Jan 06;180:1-12. doi: 10.1016/j.freeradbiomed.2022.01.002. Epub 2022 Jan 06.

Oxidative damage including lipid peroxidation is widely reported in Alzheimer's disease (AD) with the peroxidation of phospholipids in membranes being the driver of ferroptosis, an iron-dependent oxidative form of cell death. However, the importance of ferroptosis in AD remains...

Enhanced defense against ferroptosis ameliorates cognitive impairment and reduces neurodegeneration in 5xFAD mice.

Free radical biology & medicine

Chen L, Dar NJ, Na R, McLane KD, Yoo K, Han X, Ran Q.
PMID: 34998934
Free Radic Biol Med. 2022 Jan 05; doi: 10.1016/j.freeradbiomed.2022.01.002. Epub 2022 Jan 05.

Oxidative damage including lipid peroxidation is widely reported in Alzheimer's disease (AD) with the peroxidation of phospholipids in membranes being the driver of ferroptosis, an iron-dependent oxidative form of cell death. However, the importance of ferroptosis in AD remains...

Obstructive Jaundice Secondary to Peribiliary Cyst Within the Common Hepatic Duct.

The American surgeon

Gartland RM, Landino SM, Liang NE, Day CJ, Berger DL.
PMID: 33283523
Am Surg. 2020 Dec 07;3134820973359. doi: 10.1177/0003134820973359. Epub 2020 Dec 07.

No abstract available.

Investigation into Small Molecule Isomeric Glucuronide Metabolite Differentiation Using .

Journal of the American Society for Mass Spectrometry

Connolly JRFB, Munoz-Muriedas J, Lapthorn C, Higton D, Vissers JPC, Webb A, Beaumont C, Dear GJ.
PMID: 34296869
J Am Soc Mass Spectrom. 2021 Aug 04;32(8):1976-1986. doi: 10.1021/jasms.0c00427. Epub 2021 Jul 23.

Identifying isomeric metabolites remains a challenging and time-consuming process with both sensitivity and unambiguous structural assignment typically only achieved through the combined use of LC-MS and NMR. Ion mobility mass spectrometry (IMMS) has the potential to produce timely and...

Showing 289 to 300 of 300 entries